{"id":"https://openalex.org/W4415475703","doi":"https://doi.org/10.1681/asn.2025nbzbkyjy","title":"A Stable Aneurysm, an Unstable Kidney: A Case of Biopsy-Proven Atheroembolic Disease","display_name":"A Stable Aneurysm, an Unstable Kidney: A Case of Biopsy-Proven Atheroembolic Disease","publication_year":2025,"publication_date":"2025-10-01","ids":{"openalex":"https://openalex.org/W4415475703","doi":"https://doi.org/10.1681/asn.2025nbzbkyjy"},"language":"en","primary_location":{"id":"doi:10.1681/asn.2025nbzbkyjy","doi":"https://doi.org/10.1681/asn.2025nbzbkyjy","is_oa":false,"landing_page_url":"https://doi.org/10.1681/asn.2025nbzbkyjy","pdf_url":null,"source":{"id":"https://openalex.org/S115693375","display_name":"Journal of the American Society of Nephrology","issn_l":"1046-6673","issn":["1046-6673","1533-3450"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315620","host_organization_name":"American Society of Nephrology","host_organization_lineage":["https://openalex.org/P4310315620"],"host_organization_lineage_names":["American Society of Nephrology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Society of Nephrology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5092924249","display_name":"Nosagie Ohonba","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1320796813","display_name":"Mount Sinai Health System","ror":"https://ror.org/04kfn4587","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1320796813"]},{"id":"https://openalex.org/I2800099964","display_name":"Overlook Medical Center","ror":"https://ror.org/05resfq34","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800099964","https://openalex.org/I67339987"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nosagie Ohonba","raw_affiliation_strings":["Mount Sinai Health System, New York, New York, United States;","Overlook Medical Center, Summit, New Jersey, United States;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mount Sinai Health System, New York, New York, United States;","institution_ids":["https://openalex.org/I1320796813"]},{"raw_affiliation_string":"Overlook Medical Center, Summit, New Jersey, United States;","institution_ids":["https://openalex.org/I2800099964"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Dhwanil G. Patel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800099964","display_name":"Overlook Medical Center","ror":"https://ror.org/05resfq34","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800099964","https://openalex.org/I67339987"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dhwanil G. Patel","raw_affiliation_strings":["Overlook Medical Center, Summit, New Jersey, United States;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Overlook Medical Center, Summit, New Jersey, United States;","institution_ids":["https://openalex.org/I2800099964"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031554195","display_name":"Miroslav Sekulic","orcid":"https://orcid.org/0000-0002-7938-1816","observed_orcids":["https://orcid.org/0000-0002-7938-1816"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Miroslav Sekulic","raw_affiliation_strings":["New York-Presbyterian/Columbia University Irving Medical Center, New York, New York, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York-Presbyterian/Columbia University Irving Medical Center, New York, New York, United States","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5116104318","display_name":"Paige Seepaulsingh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800099964","display_name":"Overlook Medical Center","ror":"https://ror.org/05resfq34","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800099964","https://openalex.org/I67339987"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paige Seepaulsingh","raw_affiliation_strings":["Overlook Medical Center, Summit, New Jersey, United States;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Overlook Medical Center, Summit, New Jersey, United States;","institution_ids":["https://openalex.org/I2800099964"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112749718","display_name":"Marlin Mousa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800099964","display_name":"Overlook Medical Center","ror":"https://ror.org/05resfq34","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800099964","https://openalex.org/I67339987"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marlin Mousa","raw_affiliation_strings":["Overlook Medical Center, Summit, New Jersey, United States;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Overlook Medical Center, Summit, New Jersey, United States;","institution_ids":["https://openalex.org/I2800099964"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.36714966,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"36","issue":"10S","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13657","display_name":"Aortic Thrombus and Embolism","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13657","display_name":"Aortic Thrombus and Embolism","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11625","display_name":"Abdominal vascular conditions and treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12067","display_name":"Renal and Vascular Pathologies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/atheroembolic-renal-disease","display_name":"atheroembolic renal disease","score":0.996999979019165},{"id":"https://openalex.org/keywords/cholesterol-crystal-embolism","display_name":"cholesterol embolism","score":0.9919999837875366},{"id":"https://openalex.org/keywords/abdominal-aortic-aneurysm-repair","display_name":"abdominal aortic aneurysm repair","score":0.9399999976158142},{"id":"https://openalex.org/keywords/endovascular-repair","display_name":"endovascular repair","score":0.7009999752044678},{"id":"https://openalex.org/keywords/kidney-biopsy","display_name":"renal biopsy","score":0.6940000057220459},{"id":"https://openalex.org/keywords/acute-kidney-injury","display_name":"acute kidney injury","score":0.7070000171661377},{"id":"https://openalex.org/keywords/arteriolosclerosis","display_name":"arteriolosclerosis","score":0.6980000138282776},{"id":"https://openalex.org/keywords/iatrogenic-embolism","display_name":"iatrogenic embolism","score":0.6980000138282776},{"id":"https://openalex.org/keywords/postoperative-renal-function-decline","display_name":"postoperative renal function decline","score":0.5099999904632568},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.3190000057220459},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.6079999804496765},{"id":"https://openalex.org/keywords/anticoagulation","display_name":"anticoagulation","score":0.6499999761581421},{"id":"https://openalex.org/keywords/supportive-management","display_name":"supportive management","score":0.3799999952316284},{"id":"https://openalex.org/keywords/dialysis-avoidance","display_name":"dialysis avoidance","score":0.5640000104904175}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5533999800682068},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.47690001130104065},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.4456000030040741},{"id":"https://openalex.org/C2776356786","wikidata":"https://www.wikidata.org/wiki/Q1048573","display_name":"Tubulopathy","level":3,"score":0.3321000039577484},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.31360000371932983},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.29179999232292175},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2847999930381775},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.27390000224113464},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.2549999952316284},{"id":"https://openalex.org/C2777466421","wikidata":"https://www.wikidata.org/wiki/Q1266890","display_name":"Vascular disease","level":2,"score":0.2526000142097473}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1681/asn.2025nbzbkyjy","doi":"https://doi.org/10.1681/asn.2025nbzbkyjy","is_oa":false,"landing_page_url":"https://doi.org/10.1681/asn.2025nbzbkyjy","pdf_url":null,"source":{"id":"https://openalex.org/S115693375","display_name":"Journal of the American Society of Nephrology","issn_l":"1046-6673","issn":["1046-6673","1533-3450"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315620","host_organization_name":"American Society of Nephrology","host_organization_lineage":["https://openalex.org/P4310315620"],"host_organization_lineage_names":["American Society of Nephrology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Society of Nephrology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2002089363","https://openalex.org/W4391274601","https://openalex.org/W2946973191","https://openalex.org/W2290021261","https://openalex.org/W7208726715","https://openalex.org/W2264772472","https://openalex.org/W2887601950","https://openalex.org/W1898453426","https://openalex.org/W2038627766","https://openalex.org/W2128702615"],"abstract_inverted_index":{"Introduction:":[0],"Atheroembolic":[1],"renal":[2,92,109,146,167,308],"disease":[3,60,267],"(AERD)":[4],"is":[5,32,155,182,259,276,315],"a":[6,39,64,75,228,237],"systemic":[7,204],"manifestation":[8],"of":[9,41,77,131,203,222,242,286],"cholesterol":[10,115,158,252],"crystal":[11,116,159],"embolism,":[12],"often":[13],"underdiagnosed":[14],"due":[15],"to":[16,80,201,301],"its":[17],"insidious":[18],"onset":[19],"and":[20,31,61,100,121,138,149,177,213,256,268,284,317],"nonspecific":[21],"presentation.":[22],"It":[23],"typically":[24],"occurs":[25],"after":[26],"vascular":[27,173,288],"procedures":[28],"or":[29,106],"anticoagulation":[30,281],"associated":[33],"with":[34,56,63,90,124,136,261,306],"high":[35],"morbidity.":[36],"We":[37],"present":[38],"case":[40,216,297],"biopsy-confirmed":[42],"AERD":[43,154,303],"following":[44,143],"endovascular":[45,69],"abdominal":[46],"aortic":[47,101],"aneurysm":[48],"(AAA)":[49],"repair.":[50,70],"Case":[51],"Description:":[52],"A":[53,108],"69-year-old":[54],"man":[55],"hypertension,":[57,212],"coronary":[58],"artery":[59,98],"AAA":[62],"penetrating":[65],"ulcer":[66],"underwent":[67],"successful":[68],"His":[71],"creatinine":[72,230],"rose":[73],"from":[74,161],"baseline":[76],"1.0":[78],"mg/dL":[79,82],"1.8":[81],"at":[83,111,184,272],"discharge.":[84],"4":[85],"months":[86,240],"later,":[87],"he":[88,150],"presented":[89],"worsening":[91],"function":[93,147],"(creatinine":[94],"4.82":[95],"mg/dL).":[96],"Renal":[97],"duplex":[99],"imaging":[102,314],"ruled":[103],"out":[104],"stenosis":[105],"endoleak.":[107],"biopsy":[110],"that":[112,233],"time,":[113],"revealed":[114],"emboli":[117],"involving":[118],"small":[119,166],"arteries":[120,255],"glomeruli,":[122],"along":[123],"severe":[125],"arteriolosclerosis.":[126],"These":[127],"findings":[128],"were":[129],"suggestive":[130],"AERD.":[132,223],"He":[133],"was":[134],"managed":[135],"antihypertensives":[137],"supportive":[139],"care.":[140],"Over":[141],"the":[142,218,225,243,299],"months,":[144],"his":[145],"stabilized,":[148,234],"avoided":[151],"dialysis.":[152],"Discussion:":[153],"caused":[156],"by":[157,236],"embolization":[160],"ulcerated":[162],"atherosclerotic":[163],"plaques":[164],"into":[165],"arteries.":[168],"Common":[169],"iatrogenic":[170],"triggers":[171],"include":[172,208],"surgery,":[174],"catheterization,":[175],"thrombolysis,":[176],"anticoagulation.":[178],"Incidence":[179],"post-aortic":[180],"surgery":[181],"estimated":[183],"1-4%,":[185],"but":[186],"autopsy":[187],"studies":[188],"suggest":[189],"subclinical":[190],"rates":[191],"may":[192],"be":[193],"higher.":[194],"The":[195],"kidneys":[196],"are":[197],"involved":[198],"in":[199,254,304],"up":[200],"50%":[202],"cases.":[205],"Risk":[206],"factors":[207],"age,":[209],"male":[210],"sex,":[211],"atherosclerosis.":[214],"This":[215,296],"underscores":[217],"delayed,":[219],"progressive":[220,307],"nature":[221],"Notably,":[224],"patient":[226],"had":[227],"brief":[229],"rise":[231],"post-surgery":[232],"followed":[235],"late":[238],"surge":[239],"later\u2014typical":[241],"disease's":[244],"biphasic":[245],"pattern.":[246],"Definitive":[247],"diagnosis":[248],"requires":[249],"biopsy,":[250],"showing":[251],"clefts":[253],"arterioles.":[257],"Prognosis":[258],"poor,":[260],"over":[262],"40%":[263],"developing":[264],"end-stage":[265],"kidney":[266],"mortality":[269],"nearing":[270],"60%":[271],"one":[273],"year.":[274],"Management":[275],"supportive:":[277],"blood":[278],"pressure":[279],"control,":[280],"cessation,":[282],"statins,":[283],"avoidance":[285],"further":[287],"insult.":[289],"Steroids":[290],"have":[291],"not":[292],"shown":[293],"consistent":[294],"benefit.":[295],"highlights":[298],"need":[300],"recognize":[302],"patients":[305],"failure":[309],"post-vascular":[310],"interventions,":[311],"especially":[312],"when":[313],"unrevealing":[316],"urinalysis":[318],"lacks":[319],"active":[320],"sediment.":[321]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2025-10-23T00:00:00"}