{"id":"https://openalex.org/W4415475359","doi":"https://doi.org/10.1681/asn.202520y42za7","title":"Risk of Kidney Failure by Diagnosis and Histology in Diabetes","display_name":"Risk of Kidney Failure by Diagnosis and Histology in Diabetes","publication_year":2025,"publication_date":"2025-10-01","ids":{"openalex":"https://openalex.org/W4415475359","doi":"https://doi.org/10.1681/asn.202520y42za7"},"language":"en","primary_location":{"id":"doi:10.1681/asn.202520y42za7","doi":"https://doi.org/10.1681/asn.202520y42za7","is_oa":false,"landing_page_url":"https://doi.org/10.1681/asn.202520y42za7","pdf_url":null,"source":{"id":"https://openalex.org/S115693375","display_name":"Journal of the American Society of Nephrology","issn_l":"1046-6673","issn":["1046-6673","1533-3450"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315620","host_organization_name":"American Society of Nephrology","host_organization_lineage":["https://openalex.org/P4310315620"],"host_organization_lineage_names":["American Society of Nephrology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Society of Nephrology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046793050","display_name":"Katherine R. Tuttle","orcid":"https://orcid.org/0000-0002-2235-0103","observed_orcids":["https://orcid.org/0000-0002-2235-0103"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Katherine R. Tuttle","raw_affiliation_strings":["Providence Health and Services, Spokane, Washington, United States;","University of Washington School of Medicine, Seattle, Washington, United States;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Providence Health and Services, Spokane, Washington, United States;","institution_ids":[]},{"raw_affiliation_string":"University of Washington School of Medicine, Seattle, Washington, United States;","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010248787","display_name":"Lindsey M. Kornowske","orcid":"https://orcid.org/0009-0005-5852-1209","observed_orcids":["https://orcid.org/0009-0005-5852-1209"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lindsey M. Kornowske","raw_affiliation_strings":["Providence Health and Services, Spokane, Washington, United States;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Providence Health and Services, Spokane, Washington, United States;","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061317769","display_name":"Jonathan E. Zuckerman","orcid":"https://orcid.org/0000-0001-9758-2147","observed_orcids":["https://orcid.org/0000-0001-9758-2147"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonathan E. Zuckerman","raw_affiliation_strings":["University of California Los Angeles David Geffen School of Medicine, Los Angeles, California, United States;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California Los Angeles David Geffen School of Medicine, Los Angeles, California, United States;","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5125534383","display_name":"Leonid Shpaner","orcid":"https://orcid.org/0009-0007-5311-8095","observed_orcids":["https://orcid.org/0009-0007-5311-8095"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leonid Shpaner","raw_affiliation_strings":["University of California Los Angeles David Geffen School of Medicine, Los Angeles, California, United States;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California Los Angeles David Geffen School of Medicine, Los Angeles, California, United States;","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029948058","display_name":"Panayiotis Petousis","orcid":"https://orcid.org/0000-0002-0696-608X","observed_orcids":["https://orcid.org/0000-0002-0696-608X"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Panayiotis Petousis","raw_affiliation_strings":["University of California Los Angeles David Geffen School of Medicine, Los Angeles, California, United States;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California Los Angeles David Geffen School of Medicine, Los Angeles, California, United States;","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080390560","display_name":"Cynthia C. Nast","orcid":"https://orcid.org/0000-0001-8243-9073","observed_orcids":["https://orcid.org/0000-0001-8243-9073"]},"institutions":[{"id":"https://openalex.org/I1282927834","display_name":"Cedars-Sinai Medical Center","ror":"https://ror.org/02pammg90","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834"]},{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cynthia C. Nast","raw_affiliation_strings":["Cedars-Sinai, Los Angeles, California, United States;","University of California Los Angeles David Geffen School of Medicine, Los Angeles, California, United States;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cedars-Sinai, Los Angeles, California, United States;","institution_ids":["https://openalex.org/I1282927834"]},{"raw_affiliation_string":"University of California Los Angeles David Geffen School of Medicine, Los Angeles, California, United States;","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009102261","display_name":"Susanne B. Nicholas","orcid":"https://orcid.org/0000-0003-3535-9120","observed_orcids":["https://orcid.org/0000-0003-3535-9120"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susanne B. Nicholas","raw_affiliation_strings":["University of California Los Angeles David Geffen School of Medicine, Los Angeles, California, United States;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California Los Angeles David Geffen School of Medicine, Los Angeles, California, United States;","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051133604","display_name":"Keith C. Norris","orcid":"https://orcid.org/0000-0003-3071-0700","observed_orcids":["https://orcid.org/0000-0003-3071-0700"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Keith C. Norris","raw_affiliation_strings":["University of California Los Angeles David Geffen School of Medicine, Los Angeles, California, United States;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California Los Angeles David Geffen School of Medicine, Los Angeles, California, United States;","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057626833","display_name":"Cami R. Jones","orcid":"https://orcid.org/0009-0007-3382-5753","observed_orcids":["https://orcid.org/0009-0007-3382-5753"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Cami R. Jones","raw_affiliation_strings":["Providence Health and Services, Spokane, Washington, United States;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Providence Health and Services, Spokane, Washington, United States;","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053504850","display_name":"Chakradhari Inampudi","orcid":"https://orcid.org/0000-0003-2940-6330","observed_orcids":["https://orcid.org/0000-0003-2940-6330"]},"institutions":[{"id":"https://openalex.org/I153297377","display_name":"Medical University of South Carolina","ror":"https://ror.org/012jban78","country_code":"US","type":"education","lineage":["https://openalex.org/I153297377"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chakradhari Inampudi","raw_affiliation_strings":["Medical University of South Carolina, Charleston, South Carolina, United States;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical University of South Carolina, Charleston, South Carolina, United States;","institution_ids":["https://openalex.org/I153297377"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004818333","display_name":"Kenn B. Daratha","orcid":"https://orcid.org/0000-0002-9194-4140","observed_orcids":["https://orcid.org/0000-0002-9194-4140"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kenn B. Daratha","raw_affiliation_strings":["Providence Health and Services, Spokane, Washington, United States;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Providence Health and Services, Spokane, Washington, United States;","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067920675","display_name":"Marino A. Bruce","orcid":"https://orcid.org/0000-0002-0643-1640","observed_orcids":["https://orcid.org/0000-0002-0643-1640"]},"institutions":[{"id":"https://openalex.org/I2801525821","display_name":"University of Houston System","ror":"https://ror.org/040vwpm13","country_code":"US","type":"education","lineage":["https://openalex.org/I2801525821"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marino A. Bruce","raw_affiliation_strings":["University of Houston System, Houston, Texas, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Houston System, Houston, Texas, United States","institution_ids":["https://openalex.org/I2801525821"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005596615","display_name":"Radica Z. Alicic","orcid":"https://orcid.org/0000-0002-5437-5700","observed_orcids":["https://orcid.org/0000-0002-5437-5700"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Radica Z. Alicic","raw_affiliation_strings":["Providence Health and Services, Spokane, Washington, United States;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Providence Health and Services, Spokane, Washington, United States;","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.3324998,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"36","issue":"10S","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/failure","display_name":"failure","score":0.7839999794960022},{"id":"https://openalex.org/keywords/diabetic-nephropathy","display_name":"diabetic nephropathy","score":0.9890000224113464},{"id":"https://openalex.org/keywords/renal-biopsy-histology","display_name":"renal biopsy histology","score":0.8579999804496765},{"id":"https://openalex.org/keywords/kidney-failure-risk-prediction","display_name":"kidney failure risk prediction","score":0.652999997138977},{"id":"https://openalex.org/keywords/nodular-sclerosis","display_name":"nodular sclerosis","score":0.6119999885559082},{"id":"https://openalex.org/keywords/arteriolar-hyalinosis","display_name":"arteriolar hyalinosis","score":0.8999999761581421},{"id":"https://openalex.org/keywords/global-glomerulosclerosis","display_name":"global glomerulosclerosis","score":0.9449999928474426},{"id":"https://openalex.org/keywords/social-determinants-of-health","display_name":"social determinants of health","score":0.8989999890327454},{"id":"https://openalex.org/keywords/social-vulnerability-index","display_name":"Social Vulnerability Index","score":0.8080000281333923},{"id":"https://openalex.org/keywords/estimated-glomerular-filtration-rate","display_name":"estimated glomerular filtration rate","score":0.8109999895095825},{"id":"https://openalex.org/keywords/urine-protein-creatinine-ratio","display_name":"urine protein-to-creatinine ratio","score":0.9309999942779541},{"id":"https://openalex.org/keywords/hba1c","display_name":"HbA1c","score":0.777999997138977},{"id":"https://openalex.org/keywords/competing-risk-of-death","display_name":"competing risk of death","score":0.6620000004768372},{"id":"https://openalex.org/keywords/diabetes-complications","display_name":"diabetes complications","score":0.5899999737739563},{"id":"https://openalex.org/keywords/kidney-transplantation","display_name":"kidney transplantation","score":0.4269999861717224},{"id":"https://openalex.org/keywords/dialysis","display_name":"dialysis","score":0.996999979019165}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8884999752044678},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.7044000029563904},{"id":"https://openalex.org/C57742111","wikidata":"https://www.wikidata.org/wiki/Q7168","display_name":"Histology","level":2,"score":0.6904000043869019},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.48399999737739563},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.4657000005245209},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.4609000086784363},{"id":"https://openalex.org/C54847362","wikidata":"https://www.wikidata.org/wiki/Q177635","display_name":"Nephrology","level":2,"score":0.3582000136375427},{"id":"https://openalex.org/C2779922275","wikidata":"https://www.wikidata.org/wiki/Q1129105","display_name":"Diabetic nephropathy","level":3,"score":0.313400000333786},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.29820001125335693},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2946999967098236},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.29100000858306885},{"id":"https://openalex.org/C2781184683","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Nephropathy","level":3,"score":0.2671999931335449},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.2572000026702881}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1681/asn.202520y42za7","doi":"https://doi.org/10.1681/asn.202520y42za7","is_oa":false,"landing_page_url":"https://doi.org/10.1681/asn.202520y42za7","pdf_url":null,"source":{"id":"https://openalex.org/S115693375","display_name":"Journal of the American Society of Nephrology","issn_l":"1046-6673","issn":["1046-6673","1533-3450"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315620","host_organization_name":"American Society of Nephrology","host_organization_lineage":["https://openalex.org/P4310315620"],"host_organization_lineage_names":["American Society of Nephrology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Society of Nephrology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4396996832","https://openalex.org/W7116692190","https://openalex.org/W2750688429","https://openalex.org/W7222313900","https://openalex.org/W4396992788","https://openalex.org/W2590169485","https://openalex.org/W4403812361","https://openalex.org/W4312172941","https://openalex.org/W3019754359","https://openalex.org/W2956462305"],"abstract_inverted_index":{"Background:":[0],"Risk":[1],"of":[2,109,115,121,136,206,248,258,286],"kidney":[3,23,35,47,83,94,116,171,207,287],"failurewith":[4],"diabetic":[5],"nephropathy":[6],"(DN)":[7],"versus":[8],"another":[9],"diagnosis":[10,17,30,60],"(non-DN)":[11],"or":[12,93,252],"mixed-DN":[13,185,253],"(DN":[14],"and":[15,31,51,61,64,66,96,103,131,145,189,235,268,274,284],"non-DN)":[16],"is":[18],"unknown.":[19],"This":[20],"study":[21,39,125],"evaluated":[22],"biopsies":[24],"from":[25,71,78],"patients":[26,41,249],"with":[27,42,118,178,250,271],"diabetes":[28,43],"for":[29,59,82,170,197],"histology":[32],"to":[33],"predict":[34],"failure.":[36],"Methods:":[37],"The":[38,124,163,202,260],"included":[40],"who":[44],"had":[45,132],"a":[46,133],"biopsy":[48,79],"at":[49],"Providence":[50],"UCLA":[52],"Health":[53],"systems":[54],"in":[55,175,245],"2015-2017.":[56],"Pathology":[57],"reports":[58],"histologic":[62],"features,":[63],"demographic":[65],"clinical":[67,272],"data":[68],"were":[69,76,199,212,264],"extracted":[70],"electronic":[72],"health":[73],"records.":[74],"Patients":[75],"followed":[77,183],"through":[80],"2023":[81],"failure":[84,117,172,208,243,288],"(estimated":[85],"glomerular":[86],"filtration":[87],"rate-eGFR":[88],"<15":[89],"mL/min/1.73":[90,143],"m2,":[91],"dialysis,":[92],"transplant)":[95],"death.":[97,122],"Cumulative":[98],"incidence":[99,283],"(CMI)":[100],"was":[101,128,141,153,159,173],"estimated":[102],"SHapley":[104],"Additive":[105],"exPlanations":[106],"(SHAP)":[107],"analysis":[108],"random":[110],"survival":[111],"forests":[112],"ranked":[113],"predictors":[114,205,263,285],"competing":[119],"risk":[120],"Results:":[123],"population":[126],"(N=477)":[127],"54%":[129],"male":[130],"mean\u00b1SD":[134],"age":[135],"60\u00b112":[137],"years.":[138,162],"Baseline":[139],"eGFR":[140],"38\u00b126":[142],"m2":[144],"median":[146],"(interquartile":[147],"range)":[148],"urine":[149],"protein-to-creatinine":[150],"ratio":[151],"(UPCR)":[152],"5":[154],"(2-9)":[155],"g/g.":[156],"Median":[157],"follow-up":[158],"6.4":[160],"(5.2-7.5)":[161],"2-year":[164],"CMI":[165],"(95%":[166],"confidence":[167],"interval":[168],"[CI])":[169],"highest":[174],"the":[176],"group":[177],"DN":[179,233,251,269],"(n=192;":[180],"60%":[181],"[53%-67%]),":[182],"by":[184],"(n=181;":[186],"53%":[187],"[45%-60%]),":[188],"non-DN":[190],"(n=104;":[191],"39%":[192],"[29%-48%],":[193],"Figure":[194],"A).":[195],"CMIs":[196],"death":[198],"much":[200],"lower.":[201],"top":[203],"10":[204],"(SHAP":[209],"C-index":[210],"0.23)":[211],"lower":[213],"eGFR,":[214],"nodular":[215],"sclerosis,":[216],"younger":[217],"age,":[218],"higher":[219,223,227,231],"social":[220,275],"vulnerability":[221],"index,":[222,230],"UPCR,":[224],"arteriolar":[225],"hyalinosis,":[226],"body":[228],"mass":[229],"HbA1c,":[232],"diagnosis,":[234],">50%":[236],"global":[237],"glomerulosclerosis":[238],"(Figure":[239],"B).":[240],"Conclusion:":[241],"Kidney":[242],"occurred":[244],"over":[246],"half":[247],"diagnoses":[254],"within":[255],"2":[256],"years":[257],"biopsy.":[259],"most":[261],"important":[262],"specific":[265],"histological":[266],"features":[267],"along":[270],"characteristics":[273],"determinants.":[276],"Funding:":[277],"Commercial":[278],"Support":[279],"-":[280],"Goldfinch":[281],"BioCumulative":[282]},"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2025-10-23T00:00:00"}