{"id":"https://openalex.org/W4415328283","doi":"https://doi.org/10.7759/cureus.94876","title":"An Uncommon Presentation of Growing Teratoma Syndrome in a Patient Treated for Testicular Immature Teratoma: A Case Report","display_name":"An Uncommon Presentation of Growing Teratoma Syndrome in a Patient Treated for Testicular Immature Teratoma: A Case Report","publication_year":2025,"publication_date":"2025-10-18","ids":{"openalex":"https://openalex.org/W4415328283","doi":"https://doi.org/10.7759/cureus.94876","pmid":"https://pubmed.ncbi.nlm.nih.gov/41257105","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12622764"},"language":"en","primary_location":{"id":"doi:10.7759/cureus.94876","doi":"https://doi.org/10.7759/cureus.94876","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.94876","pdf_url":"https://www.cureus.com/articles/383537-an-uncommon-presentation-of-growing-teratoma-syndrome-in-a-patient-treated-for-testicular-immature-teratoma-a-case-report.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.cureus.com/articles/383537-an-uncommon-presentation-of-growing-teratoma-syndrome-in-a-patient-treated-for-testicular-immature-teratoma-a-case-report.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111868107","display_name":"Manal Lyagoubi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108110","display_name":"Mohamed I University","ror":"https://ror.org/01ejxf797","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210108110"]},{"id":"https://openalex.org/I4210141296","display_name":"Centre Hospitalo-Universitaire Mohammed VI d'Oujda","ror":"https://ror.org/04bmqy315","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210141296"]}],"countries":["MA"],"is_corresponding":true,"raw_author_name":"Manal Lyagoubi","raw_affiliation_strings":["Pathology Department, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pathology Department, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR","institution_ids":["https://openalex.org/I4210108110","https://openalex.org/I4210141296"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017199974","display_name":"Nadir Miry","orcid":"https://orcid.org/0000-0002-0564-3166","observed_orcids":["https://orcid.org/0000-0002-0564-3166"]},"institutions":[{"id":"https://openalex.org/I4210108110","display_name":"Mohamed I University","ror":"https://ror.org/01ejxf797","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210108110"]},{"id":"https://openalex.org/I4210141296","display_name":"Centre Hospitalo-Universitaire Mohammed VI d'Oujda","ror":"https://ror.org/04bmqy315","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210141296"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Nadir Miry","raw_affiliation_strings":["Pathology Department, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pathology Department, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR","institution_ids":["https://openalex.org/I4210108110","https://openalex.org/I4210141296"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015951266","display_name":"Nassira Karich","orcid":"https://orcid.org/0000-0002-7477-6317","observed_orcids":["https://orcid.org/0000-0002-7477-6317"]},"institutions":[{"id":"https://openalex.org/I4210108110","display_name":"Mohamed I University","ror":"https://ror.org/01ejxf797","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210108110"]},{"id":"https://openalex.org/I4210141296","display_name":"Centre Hospitalo-Universitaire Mohammed VI d'Oujda","ror":"https://ror.org/04bmqy315","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210141296"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Nassira Karich","raw_affiliation_strings":["Pathology Department, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pathology Department, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR","institution_ids":["https://openalex.org/I4210108110","https://openalex.org/I4210141296"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045015184","display_name":"Anass Haloui","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108110","display_name":"Mohamed I University","ror":"https://ror.org/01ejxf797","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210108110"]},{"id":"https://openalex.org/I4210141296","display_name":"Centre Hospitalo-Universitaire Mohammed VI d'Oujda","ror":"https://ror.org/04bmqy315","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210141296"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Anass Haloui","raw_affiliation_strings":["Pathology Department, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pathology Department, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR","institution_ids":["https://openalex.org/I4210108110","https://openalex.org/I4210141296"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5066713730","display_name":"Amal Bennani","orcid":"https://orcid.org/0000-0001-5293-3636","observed_orcids":["https://orcid.org/0000-0001-5293-3636"]},"institutions":[{"id":"https://openalex.org/I4210108110","display_name":"Mohamed I University","ror":"https://ror.org/01ejxf797","country_code":"MA","type":"education","lineage":["https://openalex.org/I4210108110"]},{"id":"https://openalex.org/I4210141296","display_name":"Centre Hospitalo-Universitaire Mohammed VI d'Oujda","ror":"https://ror.org/04bmqy315","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210141296"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Amal Bennani","raw_affiliation_strings":["Pathology Department, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pathology Department, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda, MAR","institution_ids":["https://openalex.org/I4210108110","https://openalex.org/I4210141296"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5111868107"],"corresponding_institution_ids":["https://openalex.org/I4210108110","https://openalex.org/I4210141296"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"17","issue":"10","first_page":"e94876","last_page":"e94876"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11069","display_name":"Testicular diseases and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11069","display_name":"Testicular diseases and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12183","display_name":"Teratomas and Epidermoid Cysts","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10550","display_name":"Ovarian cancer diagnosis and treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/growing-teratoma-syndrome","display_name":"growing teratoma syndrome","score":0.9980000257492065},{"id":"https://openalex.org/keywords/immature-teratoma","display_name":"immature teratoma","score":0.8349999785423279},{"id":"https://openalex.org/keywords/testicular-germ-cell-tumors","display_name":"testicular germ cell tumors","score":0.9380000233650208},{"id":"https://openalex.org/keywords/nonseminomatous-germ-cell-tumors","display_name":"non-seminoma","score":0.9229999780654907},{"id":"https://openalex.org/keywords/mature-teratoma","display_name":"mature teratoma","score":0.824999988079071},{"id":"https://openalex.org/keywords/post-chemotherapy-complications","display_name":"post-chemotherapy complications","score":0.7929999828338623},{"id":"https://openalex.org/keywords/lymphadenopathy","display_name":"lymphadenopathy","score":0.7239999771118164},{"id":"https://openalex.org/keywords/tumor-marker-normalization","display_name":"tumor marker normalization","score":0.7289999723434448},{"id":"https://openalex.org/keywords/surgical-excision","display_name":"surgical excision","score":0.828000009059906},{"id":"https://openalex.org/keywords/multidisciplinary-follow-up","display_name":"multidisciplinary follow-up","score":0.9100000262260437}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9790999889373779},{"id":"https://openalex.org/C2778889167","wikidata":"https://www.wikidata.org/wiki/Q6004750","display_name":"Immature teratoma","level":4,"score":0.7483999729156494},{"id":"https://openalex.org/C2777601897","wikidata":"https://www.wikidata.org/wiki/Q3409113","display_name":"Presentation (obstetrics)","level":2,"score":0.7245000004768372},{"id":"https://openalex.org/C2776057878","wikidata":"https://www.wikidata.org/wiki/Q200741","display_name":"Teratoma","level":2,"score":0.6680999994277954},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.6103000044822693},{"id":"https://openalex.org/C2776938808","wikidata":"https://www.wikidata.org/wiki/Q1737977","display_name":"Germ cell tumors","level":3,"score":0.578000009059906},{"id":"https://openalex.org/C2910174135","wikidata":"https://www.wikidata.org/wiki/Q200741","display_name":"Mature teratoma","level":3,"score":0.4659999907016754},{"id":"https://openalex.org/C2780849966","wikidata":"https://www.wikidata.org/wiki/Q170758","display_name":"Lymph node","level":2,"score":0.436599999666214},{"id":"https://openalex.org/C2779122487","wikidata":"https://www.wikidata.org/wiki/Q281579","display_name":"Germ cell","level":3,"score":0.4207000136375427},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.41339999437332153},{"id":"https://openalex.org/C3019796121","wikidata":"https://www.wikidata.org/wiki/Q5048356","display_name":"Case presentation","level":2,"score":0.37689998745918274},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3587000072002411},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.31189998984336853},{"id":"https://openalex.org/C3020501284","wikidata":"https://www.wikidata.org/wiki/Q849359","display_name":"Multidisciplinary team","level":2,"score":0.30889999866485596},{"id":"https://openalex.org/C3019864225","wikidata":"https://www.wikidata.org/wiki/Q5867482","display_name":"Combination chemotherapy","level":3,"score":0.2863999903202057},{"id":"https://openalex.org/C2779066085","wikidata":"https://www.wikidata.org/wiki/Q9384","display_name":"Testicle","level":2,"score":0.28110000491142273},{"id":"https://openalex.org/C447327","wikidata":"https://www.wikidata.org/wiki/Q1639798","display_name":"Index case","level":3,"score":0.27320000529289246},{"id":"https://openalex.org/C2776611710","wikidata":"https://www.wikidata.org/wiki/Q16888295","display_name":"Induction chemotherapy","level":3,"score":0.2703999876976013},{"id":"https://openalex.org/C61434518","wikidata":"https://www.wikidata.org/wiki/Q932510","display_name":"General surgery","level":1,"score":0.25110000371932983}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.7759/cureus.94876","doi":"https://doi.org/10.7759/cureus.94876","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.94876","pdf_url":"https://www.cureus.com/articles/383537-an-uncommon-presentation-of-growing-teratoma-syndrome-in-a-patient-treated-for-testicular-immature-teratoma-a-case-report.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:11430842","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12622764","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:41257105","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41257105","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"Case Reports"},{"id":"pmh:oai:pubmedcentral.nih.gov:12622764","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12622764/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.7759/cureus.94876","doi":"https://doi.org/10.7759/cureus.94876","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.94876","pdf_url":"https://www.cureus.com/articles/383537-an-uncommon-presentation-of-growing-teratoma-syndrome-in-a-patient-treated-for-testicular-immature-teratoma-a-case-report.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4415328283.pdf","grobid_xml":"https://content.openalex.org/works/W4415328283.grobid-xml"},"referenced_works_count":13,"referenced_works":["https://openalex.org/W186377130","https://openalex.org/W1791416231","https://openalex.org/W2035773560","https://openalex.org/W2039945054","https://openalex.org/W2052981456","https://openalex.org/W2076172260","https://openalex.org/W2196766354","https://openalex.org/W2947904453","https://openalex.org/W3127603645","https://openalex.org/W3190726929","https://openalex.org/W4212847299","https://openalex.org/W4368358910","https://openalex.org/W4399354773"],"related_works":["https://openalex.org/W2947542760","https://openalex.org/W4220884708","https://openalex.org/W4411110610","https://openalex.org/W4416728814","https://openalex.org/W2973044110","https://openalex.org/W4412713846","https://openalex.org/W2511532365","https://openalex.org/W1997806472","https://openalex.org/W3126565034","https://openalex.org/W4404712386"],"abstract_inverted_index":{"Growing":[0],"teratoma":[1,22,48],"syndrome":[2],"(GTS)":[3],"is":[4,29],"an":[5,46],"uncommon":[6],"post-chemotherapy":[7],"event":[8],"in":[9,88],"non-seminomatous":[10],"germ":[11],"cell":[12],"tumors":[13],"and":[14,95,107],"presents":[15],"as":[16,68],"enlarging":[17,62],"masses":[18,65],"composed":[19],"of":[20,41,49,79,84,100],"mature":[21,69],"despite":[23],"normalized":[24,58],"markers.":[25],"As":[26],"systemic":[27],"therapy":[28],"generally":[30],"ineffective,":[31],"treatment":[32],"focuses":[33],"on":[34],"surgical":[35],"excision.":[36],"We":[37],"report":[38],"the":[39,50,77,97],"case":[40,75],"a":[42,81],"30-year-old":[43],"male":[44],"with":[45,57,72,90],"immature":[47,91],"right":[51],"testis":[52],"who,":[53],"after":[54],"completing":[55],"chemotherapy":[56,94],"tumor":[59],"markers,":[60],"developed":[61],"lymph":[63],"node":[64],"histologically":[66],"confirmed":[67],"teratoma,":[70],"consistent":[71],"GTS.":[73],"This":[74],"highlights":[76],"importance":[78],"maintaining":[80],"high":[82],"index":[83],"suspicion":[85],"for":[86],"GTS":[87],"patients":[89],"teratomas":[92],"undergoing":[93],"underscores":[96],"critical":[98],"role":[99],"multidisciplinary":[101],"follow-up":[102],"to":[103],"ensure":[104],"timely":[105],"diagnosis":[106],"effective":[108],"management.":[109]},"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2025-10-19T00:00:00"}