{"id":"https://openalex.org/W4415327100","doi":"https://doi.org/10.1016/j.ahj.2025.107291","title":"Distal versus conventional radial large-bore access for percutaneous coronary intervention of complex coronary lesions: Rationale and design of the DISCO COMPLEX randomized superiority trial","display_name":"Distal versus conventional radial large-bore access for percutaneous coronary intervention of complex coronary lesions: Rationale and design of the DISCO COMPLEX randomized superiority trial","publication_year":2025,"publication_date":"2025-10-18","ids":{"openalex":"https://openalex.org/W4415327100","doi":"https://doi.org/10.1016/j.ahj.2025.107291","pmid":"https://pubmed.ncbi.nlm.nih.gov/41115584"},"language":"en","primary_location":{"id":"doi:10.1016/j.ahj.2025.107291","doi":"https://doi.org/10.1016/j.ahj.2025.107291","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ahj.2025.107291","pdf_url":null,"source":{"id":"https://openalex.org/S46995015","display_name":"American Heart Journal","issn_l":"0002-8703","issn":["0002-8703","1097-6744"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Heart Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","datacite","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.ahj.2025.107291","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020480277","display_name":"Juan F. Iglesias","orcid":"https://orcid.org/0000-0002-1669-6036","observed_orcids":["https://orcid.org/0000-0002-1669-6036"]},"institutions":[{"id":"https://openalex.org/I4210106256","display_name":"University Hospital of Geneva","ror":"https://ror.org/01m1pv723","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210106256"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"Juan F. Iglesias","raw_affiliation_strings":["Department of Cardiology, Geneva University Hospitals, Geneva, Switzerland. Electronic address: juanfernando.iglesias@hug.ch"],"raw_orcid":"https://orcid.org/0000-0002-1669-6036","affiliations":[{"raw_affiliation_string":"Department of Cardiology, Geneva University Hospitals, Geneva, Switzerland. Electronic address: juanfernando.iglesias@hug.ch","institution_ids":["https://openalex.org/I4210106256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005839736","display_name":"Gregor Leibundgut","orcid":"https://orcid.org/0000-0002-0122-5397","observed_orcids":["https://orcid.org/0000-0002-0122-5397"]},"institutions":[{"id":"https://openalex.org/I2802542264","display_name":"University Hospital of Basel","ror":"https://ror.org/04k51q396","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802542264"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Gregor Leibundgut","raw_affiliation_strings":["Department of Cardiology, Basel University Hospital, Basel, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Basel University Hospital, Basel, Switzerland","institution_ids":["https://openalex.org/I2802542264"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051530432","display_name":"Dik Heg","orcid":"https://orcid.org/0000-0002-8766-7945","observed_orcids":["https://orcid.org/0000-0002-8766-7945"]},"institutions":[{"id":"https://openalex.org/I118564535","display_name":"University of Bern","ror":"https://ror.org/02k7v4d05","country_code":"CH","type":"education","lineage":["https://openalex.org/I118564535"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Dik Heg","raw_affiliation_strings":["Department of Clinical Research, University of Bern, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Research, University of Bern, Switzerland","institution_ids":["https://openalex.org/I118564535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083935922","display_name":"Gabriele Luigi Gasparini","orcid":"https://orcid.org/0000-0003-3653-9553","observed_orcids":["https://orcid.org/0000-0003-3653-9553"]},"institutions":[{"id":"https://openalex.org/I4210163047","display_name":"IRCCS Humanitas Research Hospital","ror":"https://ror.org/05d538656","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210163047"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Gabriele L. Gasparini","raw_affiliation_strings":["Cardio Center, IRCCS Humanitas Research Hospital, Rozzano-Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardio Center, IRCCS Humanitas Research Hospital, Rozzano-Milan, Italy","institution_ids":["https://openalex.org/I4210163047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015980094","display_name":"Grigorios Tsigkas","orcid":"https://orcid.org/0000-0002-2779-0765","observed_orcids":["https://orcid.org/0000-0002-2779-0765"]},"institutions":[{"id":"https://openalex.org/I2801754460","display_name":"General University Hospital of Patras","ror":"https://ror.org/03c3d1v10","country_code":"GR","type":"healthcare","lineage":["https://openalex.org/I2801754460"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Grigorios Tsigkas","raw_affiliation_strings":["Department of Cardiology, Patras University Hospital of Patras, Patras, Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Patras University Hospital of Patras, Patras, Greece","institution_ids":["https://openalex.org/I2801754460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025572937","display_name":"Claudiu Ungureanu","orcid":"https://orcid.org/0000-0002-1583-5882","observed_orcids":["https://orcid.org/0000-0002-1583-5882"]},"institutions":[{"id":"https://openalex.org/I4210107246","display_name":"H\u00f4pital de Jolimont","ror":"https://ror.org/01jn2rz36","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I4210107246"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Claudiu Ungureanu","raw_affiliation_strings":["Cardiovascular Department, Jolimont Hospital, La Louvi\u00e8re, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Department, Jolimont Hospital, La Louvi\u00e8re, Belgium","institution_ids":["https://openalex.org/I4210107246"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008812207","display_name":"Giuseppe Colletti","orcid":"https://orcid.org/0000-0002-6147-0925","observed_orcids":["https://orcid.org/0000-0002-6147-0925"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Giuseppe Colletti","raw_affiliation_strings":["Cardiovascular Department, Clinique Saint Joseph, Vivalia, Arlon, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Department, Clinique Saint Joseph, Vivalia, Arlon, Belgium","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059812150","display_name":"Sophie Degrauwe","orcid":"https://orcid.org/0000-0002-2484-0835","observed_orcids":["https://orcid.org/0000-0002-2484-0835"]},"institutions":[{"id":"https://openalex.org/I4210106256","display_name":"University Hospital of Geneva","ror":"https://ror.org/01m1pv723","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210106256"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Sophie Degrauwe","raw_affiliation_strings":["Department of Cardiology, Geneva University Hospitals, Geneva, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Geneva University Hospitals, Geneva, Switzerland","institution_ids":["https://openalex.org/I4210106256"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005228981","display_name":"Panagiotis Xaplanteris","orcid":"https://orcid.org/0000-0002-8741-1720","observed_orcids":["https://orcid.org/0000-0002-8741-1720"]},"institutions":[{"id":"https://openalex.org/I132053463","display_name":"Universit\u00e9 Libre de Bruxelles","ror":"https://ror.org/01r9htc13","country_code":"BE","type":"education","lineage":["https://openalex.org/I132053463"]},{"id":"https://openalex.org/I4210154425","display_name":"Centre Hospitalier Universitaire de Saint-Pierre","ror":"https://ror.org/05cmp5q80","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I4210154425"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Panagiotis Xaplanteris","raw_affiliation_strings":["Department of Cardiology, Universit\u00e9 Libre de Bruxelles (ULB), Centre Hospitalier Universitaire Saint-Pierre, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Universit\u00e9 Libre de Bruxelles (ULB), Centre Hospitalier Universitaire Saint-Pierre, Brussels, Belgium","institution_ids":["https://openalex.org/I132053463","https://openalex.org/I4210154425"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046918388","display_name":"Karsten Schenke","orcid":"https://orcid.org/0000-0002-0030-0623","observed_orcids":["https://orcid.org/0000-0002-0030-0623"]},"institutions":[{"id":"https://openalex.org/I4210123162","display_name":"Agaplesion Bethesda Krankenhaus","ror":"https://ror.org/02xwjjw58","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210123162"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Karsten Schenke","raw_affiliation_strings":["Agaplesion Bethesda Krankenhaus Bergdorf, Hamburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Agaplesion Bethesda Krankenhaus Bergdorf, Hamburg, Germany","institution_ids":["https://openalex.org/I4210123162"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040336427","display_name":"Alexandru Achim","orcid":"https://orcid.org/0000-0002-5540-3478","observed_orcids":["https://orcid.org/0000-0002-5540-3478"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alexandru Achim","raw_affiliation_strings":["Department of Cardiology, Heart Institute Niculae St\u0103ncioiu Cluj-Napoca, Cluj-Napoca, Romania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Heart Institute Niculae St\u0103ncioiu Cluj-Napoca, Cluj-Napoca, Romania","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041556534","display_name":"Maarten A.H. van Leeuwen","orcid":"https://orcid.org/0000-0002-9609-3728","observed_orcids":["https://orcid.org/0000-0002-9609-3728","https://orcid.org/0000-0002-4264-4280"]},"institutions":[{"id":"https://openalex.org/I4210146510","display_name":"Isala","ror":"https://ror.org/046a2wj10","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210146510"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Maarten AH van Leeuwen","raw_affiliation_strings":["Department of Cardiology, Isala Heart Center, Zwolle, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Isala Heart Center, Zwolle, the Netherlands","institution_ids":["https://openalex.org/I4210146510"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Maia Muresan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I118564535","display_name":"University of Bern","ror":"https://ror.org/02k7v4d05","country_code":"CH","type":"education","lineage":["https://openalex.org/I118564535"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Maia Muresan","raw_affiliation_strings":["Department of Clinical Research, University of Bern, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Research, University of Bern, Switzerland","institution_ids":["https://openalex.org/I118564535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106852512","display_name":"Shigeru Saito","orcid":"https://orcid.org/0000-0002-8940-3708","observed_orcids":["https://orcid.org/0000-0002-8940-3708"]},"institutions":[{"id":"https://openalex.org/I4210151342","display_name":"Shonan Kamakura General Hospital","ror":"https://ror.org/03xz3hj66","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210151342"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shigeru Saito","raw_affiliation_strings":["Department of Cardiology, Shonan Kamakura General Hospital, Kanagawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Shonan Kamakura General Hospital, Kanagawa, Japan","institution_ids":["https://openalex.org/I4210151342"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012217159","display_name":"Gregory Angelo Sgueglia","orcid":"https://orcid.org/0000-0001-9680-7412","observed_orcids":["https://orcid.org/0000-0001-9680-7412"]},"institutions":[{"id":"https://openalex.org/I4210143032","display_name":"St. Eugenio Hospital","ror":"https://ror.org/03h1gw307","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210143032"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Gregory A. Sgueglia","raw_affiliation_strings":["Division of Cardiology, Sant'Eugenio Hospital, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Sant'Eugenio Hospital, Rome, Italy","institution_ids":["https://openalex.org/I4210143032"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034792349","display_name":"Adel Aminian","orcid":"https://orcid.org/0000-0002-4667-9181","observed_orcids":["https://orcid.org/0000-0002-4667-9181"]},"institutions":[{"id":"https://openalex.org/I4210152698","display_name":"Grand Charleroi Hospital","ror":"https://ror.org/05ma41w62","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I4210152698"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Adel Aminian","raw_affiliation_strings":["Department of Cardiology, Centre Hospitalier Universitaire de Charleroi, Charleroi, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Centre Hospitalier Universitaire de Charleroi, Charleroi, Belgium","institution_ids":["https://openalex.org/I4210152698"]}]}],"institutions":[],"countries_distinct_count":7,"institutions_distinct_count":13,"corresponding_author_ids":["https://openalex.org/A5020480277"],"corresponding_institution_ids":["https://openalex.org/I4210106256"],"apc_list":{"value":4070,"currency":"USD","value_usd":4070},"apc_paid":{"value":4070,"currency":"USD","value_usd":4070},"fwci":1.5909,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.80193134,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"292","issue":null,"first_page":"107291","last_page":"107291"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11554","display_name":"Vascular Procedures and Complications","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11554","display_name":"Vascular Procedures and Complications","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10641","display_name":"Central Venous Catheters and Hemodialysis","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/distal-radial-access","display_name":"distal transradial access","score":0.9639999866485596},{"id":"https://openalex.org/keywords/transradial-access","display_name":"transradial access","score":0.9679999947547913},{"id":"https://openalex.org/keywords/complex-coronary-lesions","display_name":"complex coronary lesions","score":0.8899999856948853},{"id":"https://openalex.org/keywords/radial-artery-occlusion","display_name":"radial artery occlusion","score":0.8859999775886536},{"id":"https://openalex.org/keywords/percutaneous-coronary-intervention","display_name":"percutaneous coronary intervention","score":0.8429999947547913},{"id":"https://openalex.org/keywords/chronic-total-occlusion","display_name":"chronic total occlusion","score":0.8389999866485596},{"id":"https://openalex.org/keywords/left-main-coronary-artery-disease","display_name":"left main coronary artery disease","score":0.777999997138977},{"id":"https://openalex.org/keywords/bifurcation-lesions","display_name":"bifurcation lesions","score":0.8579999804496765},{"id":"https://openalex.org/keywords/hand-function","display_name":"hand function","score":0.6880000233650208},{"id":"https://openalex.org/keywords/dash-questionnaire","display_name":"DASH questionnaire","score":0.8370000123977661}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9894999861717224},{"id":"https://openalex.org/C2780400711","wikidata":"https://www.wikidata.org/wiki/Q2008344","display_name":"Percutaneous coronary intervention","level":3,"score":0.718999981880188},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5534999966621399},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.5421000123023987},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5088000297546387},{"id":"https://openalex.org/C2780813298","wikidata":"https://www.wikidata.org/wiki/Q2071287","display_name":"Percutaneous","level":2,"score":0.45989999175071716},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.385699987411499},{"id":"https://openalex.org/C2780665704","wikidata":"https://www.wikidata.org/wiki/Q959298","display_name":"Intervention (counseling)","level":2,"score":0.37389999628067017},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.3434000015258789},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.2759000062942505},{"id":"https://openalex.org/C45393284","wikidata":"https://www.wikidata.org/wiki/Q191012","display_name":"Conventional PCI","level":3,"score":0.258899986743927},{"id":"https://openalex.org/C2994432733","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary disease","level":3,"score":0.2531000077724457},{"id":"https://openalex.org/C2781274984","wikidata":"https://www.wikidata.org/wiki/Q3559674","display_name":"Interventional cardiology","level":2,"score":0.2508000135421753},{"id":"https://openalex.org/C3018906752","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary heart disease","level":2,"score":0.2506999969482422}],"mesh":[{"descriptor_ui":"D000074099","descriptor_name":"Equivalence Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015337","descriptor_name":"Multicenter Studies as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017023","descriptor_name":"Coronary Angiography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017534","descriptor_name":"Radial Artery","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D062645","descriptor_name":"Percutaneous Coronary Intervention","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D062645","descriptor_name":"Percutaneous Coronary Intervention","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.ahj.2025.107291","doi":"https://doi.org/10.1016/j.ahj.2025.107291","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ahj.2025.107291","pdf_url":null,"source":{"id":"https://openalex.org/S46995015","display_name":"American Heart Journal","issn_l":"0002-8703","issn":["0002-8703","1097-6744"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Heart Journal","raw_type":"journal-article"},{"id":"pmid:41115584","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41115584","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American heart journal","raw_type":"Journal Article"},{"id":"doi:10.48620/92043","doi":"https://doi.org/10.48620/92043","is_oa":true,"landing_page_url":"https://doi.org/10.48620/92043","pdf_url":null,"source":{"id":"https://openalex.org/S7407053152","display_name":"Open Access CRIS of the University of Bern","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"}],"best_oa_location":{"id":"doi:10.1016/j.ahj.2025.107291","doi":"https://doi.org/10.1016/j.ahj.2025.107291","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ahj.2025.107291","pdf_url":null,"source":{"id":"https://openalex.org/S46995015","display_name":"American Heart Journal","issn_l":"0002-8703","issn":["0002-8703","1097-6744"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Heart Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Study Protocol","id":"https://openalex.org/study-designs/study-protocol"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320307770","display_name":"AstraZeneca","ror":"https://ror.org/04r9x1a08"},{"id":"https://openalex.org/F4320323829","display_name":"H\u00f4pitaux Universitaires de Gen\u00e8ve","ror":"https://ror.org/01m1pv723"},{"id":"https://openalex.org/F4320325270","display_name":"Terumo","ror":null},{"id":"https://openalex.org/F4320333258","display_name":"Abbott Pharmaceuticals","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W1986309799","https://openalex.org/W2122779695","https://openalex.org/W2133099183","https://openalex.org/W2513770930","https://openalex.org/W2586646046","https://openalex.org/W2591455118","https://openalex.org/W2610867018","https://openalex.org/W2808265769","https://openalex.org/W2897984440","https://openalex.org/W2946783015","https://openalex.org/W2983805592","https://openalex.org/W3092110254","https://openalex.org/W3122220979","https://openalex.org/W3133210967","https://openalex.org/W3160388790","https://openalex.org/W3195759423","https://openalex.org/W4200152734","https://openalex.org/W4229371777","https://openalex.org/W4280503595","https://openalex.org/W4280644170","https://openalex.org/W4293452265","https://openalex.org/W4304693617","https://openalex.org/W4309494744","https://openalex.org/W4386153206","https://openalex.org/W4392351685","https://openalex.org/W4400840511","https://openalex.org/W4402064302","https://openalex.org/W4408017014","https://openalex.org/W4409030151","https://openalex.org/W4410419414"],"related_works":["https://openalex.org/W4417525271","https://openalex.org/W4411298910","https://openalex.org/W3206790856","https://openalex.org/W3045310162","https://openalex.org/W4403445411","https://openalex.org/W4416567368","https://openalex.org/W3160388790","https://openalex.org/W4311989056","https://openalex.org/W7203664554","https://openalex.org/W4403682212"],"abstract_inverted_index":{"\u2022":[0,14,27,44,60],"DRA":[1,19,36,50,69,107,128,173,214,252,339],"is":[2,25,30,48,51,63,146,211,215,245,253,326],"a":[3,86,157,169,178,204,246,292],"valid":[4],"alternative":[5,88],"to":[6,53,89,217,222,256,261,277,290,299,333],"conventional":[7,90,175,218,257,341],"TRA":[8,38,54,71,176,219,258,342],"for":[9,20,94,133,187],"coronary":[10,95,99,135,189,360],"angiography":[11,96,114],"and":[12,97,161,270],"PCI.":[13],"Randomized":[15],"evidence":[16,105],"on":[17,106,310],"large-bore":[18,35,68,138,172,213,251,338],"patients":[21,111,130,184,296,320,348],"undergoing":[22,112,131,185,349],"complex":[23,41,73,134,188,201,350],"PCI":[24,42,74,117,132,186,351],"scarce.":[26],"DISCO":[28,61,144,284,324],"COMPLEX":[29,62,145,241,285,325],"an":[31,147],"investigator-initiated":[32],"RCT":[33,66],"of":[34,127,225,266,282,294,315,337],"vs.":[37,70],"in":[39,55,72,168,182,263,280,343],"708":[40,183,295],"patients.":[43],"The":[45,124,164,208,238,287,305],"primary":[46,209],"hypothesis":[47,210],"that":[49,212],"superior":[52,216],"reducing":[56,344],"radial":[57,80,227],"artery":[58,228],"occlusion.":[59],"the":[64,223,267,283,327,335],"first":[65,306,328],"testing":[67],"with":[75,156,203,220,259,352],"7-Fr":[76,179,205,353],"guide":[77,139,206,354],"catheters.":[78,355],"Distal":[79],"access":[81,92],"(DRA)":[82],"has":[83],"emerged":[84],"as":[85],"promising":[87],"transradial":[91],"(TRA)":[93],"percutaneous":[98,359],"intervention":[100],"(PCI).":[101],"However,":[102],"existing":[103],"randomized":[104,329],"primarily":[108],"involves":[109],"low-risk":[110],"diagnostic":[113],"or":[115,200],"non-complex":[116],"using":[118,137,177],"\u22646":[119],"French":[120],"(Fr)":[121],"introducer":[122,180],"sheaths.":[123],"clinical":[125,330],"benefits":[126],"among":[129,347],"lesions":[136,190],"catheters":[140],"remain":[141],"therefore":[142],"uncertain.":[143],"investigator-initiated,":[148],"prospective,":[149],"multicenter,":[150],"international,":[151],"open-label,":[152],"randomized,":[153],"controlled":[154],"trial":[155,165,248,288,331],"blinded":[158],"outcome":[159],"assessment":[160],"superiority":[162,336],"design.":[163],"will":[166],"compare":[167],"1:1":[170],"ratio":[171],"versus":[174],"sheath":[181],"(chronic":[191],"total":[192,293],"occlusions,":[193],"left":[194],"main":[195],"disease,":[196],"heavily":[197],"calcified":[198],"lesions,":[199],"bifurcations)":[202],"catheter.":[207],"respect":[221,260],"incidence":[224],"forearm":[226],"occlusion":[229],"(RAO)":[230],"assessed":[231],"by":[232],"Doppler":[233],"ultrasound":[234],"at":[235],"hospital":[236],"discharge.":[237],"prespecified":[239],"DISCOPHILE":[240],"hand":[242],"function":[243],"substudy":[244],"non-inferiority":[247],"evaluating":[249],"whether":[250],"not":[254],"inferior":[255],"change":[262],"full-":[264],"Disabilities":[265],"Arm,":[268],"Shoulder":[269],"Hand":[271],"(DASH)":[272],"questionnaire":[273],"score":[274],"from":[275,297],"baseline":[276],"12":[278],"months":[279],"participants":[281],"trial.":[286],"aims":[289],"recruit":[291],"10":[298],"15":[300],"participating":[301],"centers":[302],"across":[303],"Europe.":[304],"patient":[307],"was":[308],"enrolled":[309],"August":[311,316],"31,":[312],"2023.":[313],"As":[314],"20,":[317],"2025,":[318],"385":[319],"have":[321],"been":[322],"included.":[323],"designed":[332],"test":[334],"over":[340],"RAO":[345],"rates":[346],"Fr,":[356],"French;":[357],"PCI,":[358],"intervention.":[361]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2025-10-19T00:00:00"}