{"id":"https://openalex.org/W4415324345","doi":"https://doi.org/10.4103/jopcs.jopcs_8_25","title":"Presentation of Malaria with Deranged Renal and Biochemical Parameters and its Association with Patient Mortality","display_name":"Presentation of Malaria with Deranged Renal and Biochemical Parameters and its Association with Patient Mortality","publication_year":2025,"publication_date":"2025-05-01","ids":{"openalex":"https://openalex.org/W4415324345","doi":"https://doi.org/10.4103/jopcs.jopcs_8_25"},"language":"en","primary_location":{"id":"doi:10.4103/jopcs.jopcs_8_25","doi":"https://doi.org/10.4103/jopcs.jopcs_8_25","is_oa":true,"landing_page_url":"https://doi.org/10.4103/jopcs.jopcs_8_25","pdf_url":null,"source":{"id":"https://openalex.org/S4210236917","display_name":"Journal of Primary Care Specialties","issn_l":"2772-3615","issn":["2772-3615","2772-3623"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Primary Care Specialties","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.4103/jopcs.jopcs_8_25","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045039285","display_name":"Akanksha D. Srivastava","orcid":"https://orcid.org/0009-0000-7059-5853","observed_orcids":["https://orcid.org/0009-0000-7059-5853"]},"institutions":[{"id":"https://openalex.org/I4210152575","display_name":"Career Institute Of Medical & Dental Sciences and Hospital","ror":"https://ror.org/04e57v876","country_code":"IN","type":"education","lineage":["https://openalex.org/I1337315214","https://openalex.org/I4210152575"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Akanksha D. Srivastava","raw_affiliation_strings":["Department of Pediatrics, Career Institute of Medical Sciences, Lucknow, Uttar Pradesh, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Career Institute of Medical Sciences, Lucknow, Uttar Pradesh, India","institution_ids":["https://openalex.org/I4210152575"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Vaishali Chauhan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210152575","display_name":"Career Institute Of Medical & Dental Sciences and Hospital","ror":"https://ror.org/04e57v876","country_code":"IN","type":"education","lineage":["https://openalex.org/I1337315214","https://openalex.org/I4210152575"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Vaishali Chauhan","raw_affiliation_strings":["Department of Pediatrics, Career Institute of Medical Sciences, Lucknow, Uttar Pradesh, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Career Institute of Medical Sciences, Lucknow, Uttar Pradesh, India","institution_ids":["https://openalex.org/I4210152575"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103249049","display_name":"Shivani Bajpai","orcid":"https://orcid.org/0009-0002-1186-7884","observed_orcids":["https://orcid.org/0009-0002-1186-7884","https://orcid.org/0000-0002-7969-9269"]},"institutions":[{"id":"https://openalex.org/I4210152575","display_name":"Career Institute Of Medical & Dental Sciences and Hospital","ror":"https://ror.org/04e57v876","country_code":"IN","type":"education","lineage":["https://openalex.org/I1337315214","https://openalex.org/I4210152575"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Shivani Bajpai","raw_affiliation_strings":["Department of Pediatrics, Career Institute of Medical Sciences, Lucknow, Uttar Pradesh, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Career Institute of Medical Sciences, Lucknow, Uttar Pradesh, India","institution_ids":["https://openalex.org/I4210152575"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085269521","display_name":"Jaigam Abbas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210152575","display_name":"Career Institute Of Medical & Dental Sciences and Hospital","ror":"https://ror.org/04e57v876","country_code":"IN","type":"education","lineage":["https://openalex.org/I1337315214","https://openalex.org/I4210152575"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Jaigam Abbas","raw_affiliation_strings":["Department of Pediatrics and Neonatology, Career Institute of Medical Sciences, Lucknow, Uttar Pradesh, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics and Neonatology, Career Institute of Medical Sciences, Lucknow, Uttar Pradesh, India","institution_ids":["https://openalex.org/I4210152575"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210152575"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"6","issue":"2","first_page":"54","last_page":"60"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/malaria","display_name":"malaria","score":0.7829999923706055},{"id":"https://openalex.org/keywords/severe-malaria","display_name":"severe malaria","score":0.9990000128746033},{"id":"https://openalex.org/keywords/pediatric-malaria","display_name":"pediatric malaria","score":0.9940000176429749},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.5090000033378601},{"id":"https://openalex.org/keywords/renal-function","display_name":"renal function","score":0.460999995470047},{"id":"https://openalex.org/keywords/serum-creatinine","display_name":"serum creatinine","score":0.8949999809265137},{"id":"https://openalex.org/keywords/liver-function-tests","display_name":"liver function tests","score":0.9070000052452087},{"id":"https://openalex.org/keywords/bilirubin","display_name":"bilirubin","score":0.8970000147819519},{"id":"https://openalex.org/keywords/aspartate-aminotransferase","display_name":"aspartate aminotransferase","score":0.7940000295639038},{"id":"https://openalex.org/keywords/hemoglobin","display_name":"hemoglobin","score":0.8130000233650208},{"id":"https://openalex.org/keywords/platelet-count","display_name":"platelet count","score":0.8709999918937683},{"id":"https://openalex.org/keywords/white-blood-cell-count","display_name":"white blood cell count","score":0.8190000057220459},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.7289999723434448}],"concepts":[{"id":"https://openalex.org/C2778048844","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Malaria","level":2,"score":0.9071000218391418},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8137000203132629},{"id":"https://openalex.org/C2910455041","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Severe Malaria","level":4,"score":0.5273000001907349},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4571000039577484},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.39410001039505005},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.34850001335144043},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.34389999508857727},{"id":"https://openalex.org/C2778371730","wikidata":"https://www.wikidata.org/wiki/Q311383","display_name":"Plasmodium falciparum","level":3,"score":0.34389999508857727},{"id":"https://openalex.org/C2778456037","wikidata":"https://www.wikidata.org/wiki/Q133244","display_name":"Jaundice","level":2,"score":0.3425999879837036},{"id":"https://openalex.org/C2778917026","wikidata":"https://www.wikidata.org/wiki/Q43041","display_name":"Hemoglobin","level":2,"score":0.32330000400543213},{"id":"https://openalex.org/C2777513400","wikidata":"https://www.wikidata.org/wiki/Q104219","display_name":"Bilirubin","level":2,"score":0.31520000100135803},{"id":"https://openalex.org/C179755657","wikidata":"https://www.wikidata.org/wiki/Q58702","display_name":"Mortality rate","level":2,"score":0.2906999886035919},{"id":"https://openalex.org/C2776877979","wikidata":"https://www.wikidata.org/wiki/Q424288","display_name":"Transaminase","level":3,"score":0.2718000113964081},{"id":"https://openalex.org/C2908793570","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Cerebral Malaria","level":4,"score":0.25619998574256897},{"id":"https://openalex.org/C2779810223","wikidata":"https://www.wikidata.org/wiki/Q5270339","display_name":"Diagnosis of malaria","level":4,"score":0.25519999861717224}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.4103/jopcs.jopcs_8_25","doi":"https://doi.org/10.4103/jopcs.jopcs_8_25","is_oa":true,"landing_page_url":"https://doi.org/10.4103/jopcs.jopcs_8_25","pdf_url":null,"source":{"id":"https://openalex.org/S4210236917","display_name":"Journal of Primary Care Specialties","issn_l":"2772-3615","issn":["2772-3615","2772-3623"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Primary Care Specialties","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:b2677ff3fabc47338a5c0e09037209fa","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/b2677ff3fabc47338a5c0e09037209fa","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Primary Care Specialties, Vol 6, Iss 2, Pp 54-60 (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.4103/jopcs.jopcs_8_25","doi":"https://doi.org/10.4103/jopcs.jopcs_8_25","is_oa":true,"landing_page_url":"https://doi.org/10.4103/jopcs.jopcs_8_25","pdf_url":null,"source":{"id":"https://openalex.org/S4210236917","display_name":"Journal of Primary Care Specialties","issn_l":"2772-3615","issn":["2772-3615","2772-3623"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Primary Care Specialties","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W1975927439","https://openalex.org/W2102499150","https://openalex.org/W2104606354","https://openalex.org/W2108453046","https://openalex.org/W2798114956","https://openalex.org/W3200923062","https://openalex.org/W4214811111","https://openalex.org/W4220912549","https://openalex.org/W4296632095","https://openalex.org/W4388293989"],"related_works":["https://openalex.org/W7124729767","https://openalex.org/W7212018615","https://openalex.org/W4407119478","https://openalex.org/W4412811625","https://openalex.org/W7213778305","https://openalex.org/W4389790283","https://openalex.org/W4408580310","https://openalex.org/W2958861643","https://openalex.org/W2058966855","https://openalex.org/W2143277934"],"abstract_inverted_index":{"Abstract":[0],"Introduction:":[1],"Malaria":[2,12,15,34,37,90,152],"is":[3,16],"a":[4],"major":[5],"pediatric":[6,51],"health":[7],"concern,":[8],"and":[9,13,38,45,58,65,70,118,135,198],"distinguishing":[10],"between":[11],"Severe":[14,36,89,151],"crucial":[17],"for":[18,79],"effective":[19],"management.":[20,201],"Objectives:":[21],"The":[22],"objective":[23],"of":[24,49,188],"the":[25,80],"study":[26,48,81],"was":[27,62,75,148],"to":[28,185],"analyze":[29],"key":[30],"laboratory":[31,178],"parameters":[32,67,179],"differentiating":[33],"from":[35],"their":[39,71],"impact":[40],"on":[41],"patient":[42,200],"outcomes.":[43],"Materials":[44],"Methods:":[46],"A":[47],"120":[50],"malaria":[52,56,60,182],"patients":[53,91],"categorized":[54],"as":[55],"(69.2%)":[57],"severe":[59],"(30.8%)":[61],"conducted.":[63],"Hematological":[64],"biochemical":[66],"were":[68,82,144,165],"compared,":[69],"association":[72],"with":[73,168],"outcomes":[74,170,187],"assessed.":[76],"Statistical":[77],"analyses":[78],"conducted":[83],"using":[84],"SPSS":[85],"version":[86],"29.":[87],"Results:":[88],"had":[92],"significantly":[93,166],"lower":[94,106],"hemoglobin":[95],"(7.31":[96],"\u00b1":[97,101,109,113],"2.82":[98],"vs.":[99,111,154],"9.53":[100],"220,":[102],"P":[103,115,125,132,141,173],"<":[104,116,174],"0.001),":[105,117],"platelets":[107],"(43200":[108],"41356.07":[110],"70300":[112],"68343.66,":[114],"higher":[119,149],"total":[120],"leukocyte":[121],"count":[122],"(m/L)":[123],"(":[124,131,140,172],"=":[126,133,142],"0.004).":[127],"Elevated":[128],"bilirubin":[129],"(mg/dL)":[130],"0.034)":[134],"serum":[136,159],"glutamic-oxaloacetic":[137],"transaminase":[138],"(IU/L)":[139],"0.035)":[143],"also":[145],"observed.":[146],"Mortality":[147],"in":[150,180,195],"(16.2%":[153],"6%).":[155],"Patients":[156],"having":[157],"deranged":[158,161],"creatinine,":[160],"liver":[162],"function":[163],"tests":[164],"associated":[167],"bad":[169],"(expiry)":[171],"0.001).":[175],"Conclusion:":[176],"Biochemical":[177],"malaria/severe":[181],"can":[183,193],"help":[184],"predict":[186],"patients.":[189],"Their":[190],"routine":[191],"assessment":[192],"aid":[194],"timely":[196],"intervention":[197],"improved":[199]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2025-10-19T00:00:00"}