{"id":"https://openalex.org/W4415322328","doi":"https://doi.org/10.1021/envhealth.5c00391","title":"Sex-Specific Biological Aging-Related Lipidomic Profiles Mediate the Impact of Urinary Polycyclic Aromatic Hydrocarbon Exposures on Cognitive Function in Healthy Older Adults","display_name":"Sex-Specific Biological Aging-Related Lipidomic Profiles Mediate the Impact of Urinary Polycyclic Aromatic Hydrocarbon Exposures on Cognitive Function in Healthy Older Adults","publication_year":2025,"publication_date":"2025-10-18","ids":{"openalex":"https://openalex.org/W4415322328","doi":"https://doi.org/10.1021/envhealth.5c00391","pmid":"https://pubmed.ncbi.nlm.nih.gov/41883380","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13010294"},"language":"en","primary_location":{"id":"doi:10.1021/envhealth.5c00391","doi":"https://doi.org/10.1021/envhealth.5c00391","is_oa":true,"landing_page_url":"https://doi.org/10.1021/envhealth.5c00391","pdf_url":"https://pubs.acs.org/doi/pdf/10.1021/envhealth.5c00391?ref=article_openPDF","source":{"id":"https://openalex.org/S4387289850","display_name":"Environment & Health","issn_l":"2833-8278","issn":["2833-8278"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","norway-1","oarl"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environment &amp; Health","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://pubs.acs.org/doi/pdf/10.1021/envhealth.5c00391?ref=article_openPDF","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103096588","display_name":"Huimin Ren","orcid":"https://orcid.org/0009-0000-2812-0053","observed_orcids":["https://orcid.org/0009-0000-2812-0053"]},"institutions":[{"id":"https://openalex.org/I184490438","display_name":"Chinese Center For Disease Control and Prevention","ror":"https://ror.org/04wktzw65","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I76569877","display_name":"Southeast University","ror":"https://ror.org/04ct4d772","country_code":"CN","type":"education","lineage":["https://openalex.org/I76569877"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huimin Ren","raw_affiliation_strings":["China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","Chinese Center for Disease Control and Prevention","School of Public Health","Southeast University","China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China","School of Public Health, Southeast University, Nanjing, Jiangsu 210009, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"Chinese Center for Disease Control and Prevention","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"School of Public Health","institution_ids":[]},{"raw_affiliation_string":"Southeast University","institution_ids":["https://openalex.org/I76569877"]},{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"School of Public Health, Southeast University, Nanjing, Jiangsu 210009, China","institution_ids":["https://openalex.org/I76569877"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112698622","display_name":"Wanying Shi","orcid":"https://orcid.org/0009-0005-8614-528X","observed_orcids":["https://orcid.org/0009-0005-8614-528X"]},"institutions":[{"id":"https://openalex.org/I184490438","display_name":"Chinese Center For Disease Control and Prevention","ror":"https://ror.org/04wktzw65","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I184693016","display_name":"China Medical University","ror":"https://ror.org/00v408z34","country_code":"TW","type":"education","lineage":["https://openalex.org/I184693016"]},{"id":"https://openalex.org/I91656880","display_name":"China Medical University","ror":"https://ror.org/032d4f246","country_code":"CN","type":"education","lineage":["https://openalex.org/I91656880"]}],"countries":["CN","TW"],"is_corresponding":false,"raw_author_name":"Wanying Shi","raw_affiliation_strings":["China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","China Medical University","Chinese Center for Disease Control and Prevention","School of Public Health","China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China","School of Public Health, China Medical University, Shenyang, Liaoning 110122, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"China Medical University","institution_ids":["https://openalex.org/I184693016","https://openalex.org/I91656880"]},{"raw_affiliation_string":"Chinese Center for Disease Control and Prevention","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"School of Public Health","institution_ids":[]},{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"School of Public Health, China Medical University, Shenyang, Liaoning 110122, China","institution_ids":["https://openalex.org/I91656880"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053754481","display_name":"Xiaojie Guo","orcid":"https://orcid.org/0000-0002-6800-2569","observed_orcids":["https://orcid.org/0000-0002-6800-2569"]},"institutions":[{"id":"https://openalex.org/I184490438","display_name":"Chinese Center For Disease Control and Prevention","ror":"https://ror.org/04wktzw65","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaojie Guo","raw_affiliation_strings":["China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","Chinese Center for Disease Control and Prevention","School of Public Health","Southern Medical University","China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"Chinese Center for Disease Control and Prevention","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"School of Public Health","institution_ids":[]},{"raw_affiliation_string":"Southern Medical University","institution_ids":["https://openalex.org/I58200834"]},{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China","institution_ids":["https://openalex.org/I184490438"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046211215","display_name":"Xiao Ma","orcid":"https://orcid.org/0000-0002-0261-0369","observed_orcids":["https://orcid.org/0000-0002-0261-0369"]},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]},{"id":"https://openalex.org/I184490438","display_name":"Chinese Center For Disease Control and Prevention","ror":"https://ror.org/04wktzw65","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210151987"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiao Ma","raw_affiliation_strings":["China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","Chinese Center for Disease Control and Prevention","School of Public Health, Cheeloo College of Medicine","Shandong University","China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"Chinese Center for Disease Control and Prevention","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"School of Public Health, Cheeloo College of Medicine","institution_ids":[]},{"raw_affiliation_string":"Shandong University","institution_ids":["https://openalex.org/I154099455"]},{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China","institution_ids":["https://openalex.org/I184490438"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jiran Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I184490438","display_name":"Chinese Center For Disease Control and Prevention","ror":"https://ror.org/04wktzw65","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I184693016","display_name":"China Medical University","ror":"https://ror.org/00v408z34","country_code":"TW","type":"education","lineage":["https://openalex.org/I184693016"]},{"id":"https://openalex.org/I91656880","display_name":"China Medical University","ror":"https://ror.org/032d4f246","country_code":"CN","type":"education","lineage":["https://openalex.org/I91656880"]}],"countries":["CN","TW"],"is_corresponding":false,"raw_author_name":"Jiran Zhang","raw_affiliation_strings":["China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","China Medical University","Chinese Center for Disease Control and Prevention","School of Public Health","China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China","School of Public Health, China Medical University, Shenyang, Liaoning 110122, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"China Medical University","institution_ids":["https://openalex.org/I184693016","https://openalex.org/I91656880"]},{"raw_affiliation_string":"Chinese Center for Disease Control and Prevention","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"School of Public Health","institution_ids":[]},{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"School of Public Health, China Medical University, Shenyang, Liaoning 110122, China","institution_ids":["https://openalex.org/I91656880"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123914179","display_name":"Yongjun Situ","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I184490438","display_name":"Chinese Center For Disease Control and Prevention","ror":"https://ror.org/04wktzw65","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yongjun Situ","raw_affiliation_strings":["China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","Chinese Center for Disease Control and Prevention","School of Public Health","Southern Medical University","China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China","School of Public Health, Southern Medical University, Guangzhou, Guangdong 510515, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"Chinese Center for Disease Control and Prevention","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"School of Public Health","institution_ids":[]},{"raw_affiliation_string":"Southern Medical University","institution_ids":["https://openalex.org/I58200834"]},{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"School of Public Health, Southern Medical University, Guangzhou, Guangdong 510515, China","institution_ids":["https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Chenfeng Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]},{"id":"https://openalex.org/I184490438","display_name":"Chinese Center For Disease Control and Prevention","ror":"https://ror.org/04wktzw65","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210151987"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chenfeng Li","raw_affiliation_strings":["China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","Chinese Center for Disease Control and Prevention","School of Public Health, Cheeloo College of Medicine","Shandong University","China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China","School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250100, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"Chinese Center for Disease Control and Prevention","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"School of Public Health, Cheeloo College of Medicine","institution_ids":[]},{"raw_affiliation_string":"Shandong University","institution_ids":["https://openalex.org/I154099455"]},{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250100, China","institution_ids":["https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005062840","display_name":"Chenlong Li","orcid":"https://orcid.org/0000-0002-5463-4661","observed_orcids":["https://orcid.org/0000-0002-5463-4661"]},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]},{"id":"https://openalex.org/I184490438","display_name":"Chinese Center For Disease Control and Prevention","ror":"https://ror.org/04wktzw65","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210151987"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chenlong Li","raw_affiliation_strings":["China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","Chinese Center for Disease Control and Prevention","School of Public Health, Cheeloo College of Medicine","Shandong University","China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China","School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250100, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"Chinese Center for Disease Control and Prevention","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"School of Public Health, Cheeloo College of Medicine","institution_ids":[]},{"raw_affiliation_string":"Shandong University","institution_ids":["https://openalex.org/I154099455"]},{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong 250100, China","institution_ids":["https://openalex.org/I154099455"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Peijie Sun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I184490438","display_name":"Chinese Center For Disease Control and Prevention","ror":"https://ror.org/04wktzw65","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210129097","display_name":"Center for Global Health","ror":"https://ror.org/02e5dc168","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934","https://openalex.org/I4210129097"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Peijie Sun","raw_affiliation_strings":["Center for Global Health, School of Public Health","China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","Chinese Center for Disease Control and Prevention","Nanjing Medical University","Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 211166, China","China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Global Health, School of Public Health","institution_ids":["https://openalex.org/I4210129097"]},{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"Chinese Center for Disease Control and Prevention","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"Nanjing Medical University","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 211166, China","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China","institution_ids":["https://openalex.org/I184490438"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102353257","display_name":"Yibo Xu","orcid":"https://orcid.org/0000-0002-6572-6676","observed_orcids":["https://orcid.org/0000-0002-6572-6676","https://orcid.org/0009-0008-6085-4952"]},"institutions":[{"id":"https://openalex.org/I184490438","display_name":"Chinese Center For Disease Control and Prevention","ror":"https://ror.org/04wktzw65","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I184693016","display_name":"China Medical University","ror":"https://ror.org/00v408z34","country_code":"TW","type":"education","lineage":["https://openalex.org/I184693016"]},{"id":"https://openalex.org/I91656880","display_name":"China Medical University","ror":"https://ror.org/032d4f246","country_code":"CN","type":"education","lineage":["https://openalex.org/I91656880"]}],"countries":["CN","TW"],"is_corresponding":false,"raw_author_name":"Yibo Xu","raw_affiliation_strings":["China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","China Medical University","Chinese Center for Disease Control and Prevention","School of Public Health","China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China","School of Public Health, China Medical University, Shenyang, Liaoning 110122, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"China Medical University","institution_ids":["https://openalex.org/I184693016","https://openalex.org/I91656880"]},{"raw_affiliation_string":"Chinese Center for Disease Control and Prevention","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"School of Public Health","institution_ids":[]},{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"School of Public Health, China Medical University, Shenyang, Liaoning 110122, China","institution_ids":["https://openalex.org/I91656880"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108315354","display_name":"Kangning Cao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I184490438","display_name":"Chinese Center For Disease Control and Prevention","ror":"https://ror.org/04wktzw65","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I197869895","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968","country_code":"CN","type":"education","lineage":["https://openalex.org/I197869895"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kangning Cao","raw_affiliation_strings":["Anhui Medical University","China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","Chinese Center for Disease Control and Prevention","School of Public Health","China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anhui Medical University","institution_ids":["https://openalex.org/I197869895"]},{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"Chinese Center for Disease Control and Prevention","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"School of Public Health","institution_ids":[]},{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China","institution_ids":["https://openalex.org/I184490438"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101270309","display_name":"Jiankun Qian","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I184490438","display_name":"Chinese Center For Disease Control and Prevention","ror":"https://ror.org/04wktzw65","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I184693016","display_name":"China Medical University","ror":"https://ror.org/00v408z34","country_code":"TW","type":"education","lineage":["https://openalex.org/I184693016"]},{"id":"https://openalex.org/I91656880","display_name":"China Medical University","ror":"https://ror.org/032d4f246","country_code":"CN","type":"education","lineage":["https://openalex.org/I91656880"]}],"countries":["CN","TW"],"is_corresponding":false,"raw_author_name":"Jiankun Qian","raw_affiliation_strings":["China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","China Medical University","Chinese Center for Disease Control and Prevention","School of Public Health","China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China","School of Public Health, China Medical University, Shenyang, Liaoning 110122, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"China Medical University","institution_ids":["https://openalex.org/I184693016","https://openalex.org/I91656880"]},{"raw_affiliation_string":"Chinese Center for Disease Control and Prevention","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"School of Public Health","institution_ids":[]},{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"School of Public Health, China Medical University, Shenyang, Liaoning 110122, China","institution_ids":["https://openalex.org/I91656880"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103183655","display_name":"Yifu Lu","orcid":"https://orcid.org/0000-0002-2563-8030","observed_orcids":["https://orcid.org/0000-0002-2563-8030"]},"institutions":[{"id":"https://openalex.org/I184490438","display_name":"Chinese Center For Disease Control and Prevention","ror":"https://ror.org/04wktzw65","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210151987"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yifu Lu","raw_affiliation_strings":["China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","Chinese Center for Disease Control and Prevention","China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China"],"raw_orcid":"https://orcid.org/0000-0002-2563-8030","affiliations":[{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"Chinese Center for Disease Control and Prevention","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China","institution_ids":["https://openalex.org/I184490438"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066720510","display_name":"Shilu Tong","orcid":"https://orcid.org/0000-0001-9579-6889","observed_orcids":["https://orcid.org/0000-0001-9579-6889"]},"institutions":[{"id":"https://openalex.org/I160993911","display_name":"Queensland University of Technology","ror":"https://ror.org/03pnv4752","country_code":"AU","type":"education","lineage":["https://openalex.org/I160993911"]},{"id":"https://openalex.org/I184490438","display_name":"Chinese Center For Disease Control and Prevention","ror":"https://ror.org/04wktzw65","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210151987"]}],"countries":["AU","CN"],"is_corresponding":false,"raw_author_name":"Shilu Tong","raw_affiliation_strings":["China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","Chinese Center for Disease Control and Prevention","Queensland University of Technology","School of Public Health and Social Work","China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China","School of Public Health and Social Work, Queensland University of Technology, Brisbane 4001, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"Chinese Center for Disease Control and Prevention","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"Queensland University of Technology","institution_ids":["https://openalex.org/I160993911"]},{"raw_affiliation_string":"School of Public Health and Social Work","institution_ids":[]},{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"School of Public Health and Social Work, Queensland University of Technology, Brisbane 4001, Australia","institution_ids":["https://openalex.org/I160993911"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018955823","display_name":"Xiaoming Shi","orcid":"https://orcid.org/0000-0002-7071-571X","observed_orcids":["https://orcid.org/0000-0002-7071-571X"]},"institutions":[{"id":"https://openalex.org/I184490438","display_name":"Chinese Center For Disease Control and Prevention","ror":"https://ror.org/04wktzw65","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210129097","display_name":"Center for Global Health","ror":"https://ror.org/02e5dc168","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934","https://openalex.org/I4210129097"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN","US"],"is_corresponding":true,"raw_author_name":"Xiaoming Shi","raw_affiliation_strings":["Center for Global Health, School of Public Health","China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","Chinese Center for Disease Control and Prevention","Nanjing Medical University","National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Environmental Health","Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 211166, China","China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China"],"raw_orcid":"https://orcid.org/0000-0002-7071-571X","affiliations":[{"raw_affiliation_string":"Center for Global Health, School of Public Health","institution_ids":["https://openalex.org/I4210129097"]},{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"Chinese Center for Disease Control and Prevention","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"Nanjing Medical University","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Environmental Health","institution_ids":[]},{"raw_affiliation_string":"Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 211166, China","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China","institution_ids":["https://openalex.org/I184490438"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047625768","display_name":"Song Tang","orcid":"https://orcid.org/0000-0003-3219-1422","observed_orcids":["https://orcid.org/0000-0003-3219-1422"]},"institutions":[{"id":"https://openalex.org/I184490438","display_name":"Chinese Center For Disease Control and Prevention","ror":"https://ror.org/04wktzw65","country_code":"CN","type":"government","lineage":["https://openalex.org/I184490438","https://openalex.org/I4210127390","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I4210129097","display_name":"Center for Global Health","ror":"https://ror.org/02e5dc168","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934","https://openalex.org/I4210129097"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN","US"],"is_corresponding":true,"raw_author_name":"Song Tang","raw_affiliation_strings":["Center for Global Health, School of Public Health","China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","Chinese Center for Disease Control and Prevention","Nanjing Medical University","National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Environmental Health","Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 211166, China","China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China"],"raw_orcid":"https://orcid.org/0000-0003-3219-1422","affiliations":[{"raw_affiliation_string":"Center for Global Health, School of Public Health","institution_ids":["https://openalex.org/I4210129097"]},{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"Chinese Center for Disease Control and Prevention","institution_ids":["https://openalex.org/I184490438"]},{"raw_affiliation_string":"Nanjing Medical University","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Environmental Health","institution_ids":[]},{"raw_affiliation_string":"Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu 211166, China","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"China CDC Key Laboratory of Environment and Population Health, National Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing 100021, China","institution_ids":["https://openalex.org/I184490438"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5018955823","https://openalex.org/A5047625768"],"corresponding_institution_ids":["https://openalex.org/I184490438","https://openalex.org/I4210129097","https://openalex.org/I83519826"],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":{"value":3500,"currency":"USD","value_usd":3500},"fwci":1.4304,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.74914343,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":98},"biblio":{"volume":"4","issue":"3","first_page":"408","last_page":"419"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10122","display_name":"Toxic Organic Pollutants Impact","score":0.9437999725341797,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10122","display_name":"Toxic Organic Pollutants Impact","score":0.9437999725341797,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14393","display_name":"Health, Environment, Cognitive Aging","score":0.022099999710917473,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10686","display_name":"Effects and risks of endocrine disrupting chemicals","score":0.005100000184029341,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/polycyclic-aromatic-hydrocarbons","display_name":"polycyclic aromatic hydrocarbons","score":1.0},{"id":"https://openalex.org/keywords/cognitive-decline","display_name":"cognitive decline","score":0.871999979019165},{"id":"https://openalex.org/keywords/biological-aging","display_name":"biological aging","score":0.9710000157356262},{"id":"https://openalex.org/keywords/lipidomics","display_name":"lipidomics","score":0.7310000061988831},{"id":"https://openalex.org/keywords/phosphatidylethanolamine","display_name":"phosphatidylethanolamine","score":0.8629999756813049},{"id":"https://openalex.org/keywords/phosphatidylcholine","display_name":"phosphatidylcholine","score":0.9990000128746033},{"id":"https://openalex.org/keywords/2-naphthol","display_name":"2-naphthol","score":0.9539999961853027},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.9150000214576721},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.6549999713897705},{"id":"https://openalex.org/keywords/pah-mixtures","display_name":"PAH mixtures","score":0.8489999771118164},{"id":"https://openalex.org/keywords/mediation-analysis","display_name":"mediation analysis","score":0.5989999771118164}],"concepts":[{"id":"https://openalex.org/C2780241833","wikidata":"https://www.wikidata.org/wiki/Q6556375","display_name":"Lipidome","level":3,"score":0.8759999871253967},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.6748999953269958},{"id":"https://openalex.org/C58017582","wikidata":"https://www.wikidata.org/wiki/Q6556376","display_name":"Lipidomics","level":2,"score":0.49380001425743103},{"id":"https://openalex.org/C2984863031","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Cognitive decline","level":4,"score":0.49059998989105225},{"id":"https://openalex.org/C180899940","wikidata":"https://www.wikidata.org/wiki/Q117982","display_name":"Lipid signaling","level":3,"score":0.43070000410079956},{"id":"https://openalex.org/C179420905","wikidata":"https://www.wikidata.org/wiki/Q223871","display_name":"Mediation","level":2,"score":0.4043999910354614},{"id":"https://openalex.org/C77411442","wikidata":"https://www.wikidata.org/wiki/Q181100","display_name":"Urinary system","level":2,"score":0.3986000120639801},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.37549999356269836},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.3522999882698059},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.3264999985694885},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31850001215934753},{"id":"https://openalex.org/C9927688","wikidata":"https://www.wikidata.org/wiki/Q4915012","display_name":"Biological pathway","level":4,"score":0.31610000133514404},{"id":"https://openalex.org/C2107291","wikidata":"https://www.wikidata.org/wiki/Q14886885","display_name":"Mediator","level":2,"score":0.31349998712539673},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3089999854564667},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.29109999537467957},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.28349998593330383},{"id":"https://openalex.org/C2986811735","wikidata":"https://www.wikidata.org/wiki/Q4692577","display_name":"Cognitive aging","level":3,"score":0.2766999900341034},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2696000039577484},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2653999924659729}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1021/envhealth.5c00391","doi":"https://doi.org/10.1021/envhealth.5c00391","is_oa":true,"landing_page_url":"https://doi.org/10.1021/envhealth.5c00391","pdf_url":"https://pubs.acs.org/doi/pdf/10.1021/envhealth.5c00391?ref=article_openPDF","source":{"id":"https://openalex.org/S4387289850","display_name":"Environment & Health","issn_l":"2833-8278","issn":["2833-8278"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","norway-1","oarl"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environment &amp; Health","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13010294","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13010294/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13010294/pdf/eh5c00391.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environ Health (Wash)","raw_type":"Text"},{"id":"pmid:41883380","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41883380","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environment & health (Washington, D.C.)","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1021/envhealth.5c00391","doi":"https://doi.org/10.1021/envhealth.5c00391","is_oa":true,"landing_page_url":"https://doi.org/10.1021/envhealth.5c00391","pdf_url":"https://pubs.acs.org/doi/pdf/10.1021/envhealth.5c00391?ref=article_openPDF","source":{"id":"https://openalex.org/S4387289850","display_name":"Environment & Health","issn_l":"2833-8278","issn":["2833-8278"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","norway-1","oarl"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Environment &amp; Health","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.979200005531311,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G1496335314","display_name":null,"funder_award_id":"82304222","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G1619225195","display_name":null,"funder_award_id":"82230111","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G1636468731","display_name":null,"funder_award_id":"82025030","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5900041660","display_name":null,"funder_award_id":"2022YFC3702700","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G8544677493","display_name":null,"funder_award_id":"211166","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320320983","display_name":"Queensland University of Technology","ror":"https://ror.org/03pnv4752"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321603","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968"},{"id":"https://openalex.org/F4320322662","display_name":"Chinese Center for Disease Control and Prevention","ror":"https://ror.org/04wktzw65"},{"id":"https://openalex.org/F4320324291","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73"},{"id":"https://openalex.org/F4320324301","display_name":"China Medical University","ror":"https://ror.org/032d4f246"},{"id":"https://openalex.org/F4320332162","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4415322328.pdf","grobid_xml":"https://content.openalex.org/works/W4415322328.grobid-xml"},"referenced_works_count":77,"referenced_works":["https://openalex.org/W1581476053","https://openalex.org/W1908991493","https://openalex.org/W1967393132","https://openalex.org/W1999414566","https://openalex.org/W2005441291","https://openalex.org/W2032153758","https://openalex.org/W2043715766","https://openalex.org/W2051771016","https://openalex.org/W2061354088","https://openalex.org/W2073109594","https://openalex.org/W2096874958","https://openalex.org/W2110065044","https://openalex.org/W2112768538","https://openalex.org/W2129529988","https://openalex.org/W2133862271","https://openalex.org/W2159000911","https://openalex.org/W2159914115","https://openalex.org/W2168228291","https://openalex.org/W2254472139","https://openalex.org/W2342466305","https://openalex.org/W2808480928","https://openalex.org/W2889294609","https://openalex.org/W2949100461","https://openalex.org/W2982678657","https://openalex.org/W2995774252","https://openalex.org/W3004434362","https://openalex.org/W3034408951","https://openalex.org/W3087614317","https://openalex.org/W3094960702","https://openalex.org/W3106725626","https://openalex.org/W3123085888","https://openalex.org/W3135395873","https://openalex.org/W3184933133","https://openalex.org/W3197132305","https://openalex.org/W3201501887","https://openalex.org/W3210156413","https://openalex.org/W4200188673","https://openalex.org/W4200262820","https://openalex.org/W4214633027","https://openalex.org/W4223573151","https://openalex.org/W4224000592","https://openalex.org/W4224903096","https://openalex.org/W4226367800","https://openalex.org/W4280531467","https://openalex.org/W4287877611","https://openalex.org/W4290719784","https://openalex.org/W4294707570","https://openalex.org/W4308365150","https://openalex.org/W4309774872","https://openalex.org/W4311018579","https://openalex.org/W4317425280","https://openalex.org/W4319348510","https://openalex.org/W4320517217","https://openalex.org/W4327682581","https://openalex.org/W4366448441","https://openalex.org/W4367367363","https://openalex.org/W4372233708","https://openalex.org/W4379230153","https://openalex.org/W4386615105","https://openalex.org/W4386969538","https://openalex.org/W4387827391","https://openalex.org/W4387911272","https://openalex.org/W4390201068","https://openalex.org/W4392723798","https://openalex.org/W4392750823","https://openalex.org/W4396229532","https://openalex.org/W4396946000","https://openalex.org/W4399697851","https://openalex.org/W4400243556","https://openalex.org/W4400447750","https://openalex.org/W4400813201","https://openalex.org/W4401240337","https://openalex.org/W4401403918","https://openalex.org/W4402307954","https://openalex.org/W4403158206","https://openalex.org/W4403841679","https://openalex.org/W4414360017"],"related_works":["https://openalex.org/W7106796852","https://openalex.org/W4401403918","https://openalex.org/W2254472139","https://openalex.org/W4400238290","https://openalex.org/W4406539489","https://openalex.org/W7104044879","https://openalex.org/W4399355628","https://openalex.org/W7036262591","https://openalex.org/W7126467329","https://openalex.org/W4390994211"],"abstract_inverted_index":{"Emerging":[0],"evidence":[1],"suggests":[2],"that":[3,107],"exposure":[4,108,120],"to":[5,109,199],"polycyclic":[6],"aromatic":[7],"hydrocarbons":[8],"(PAHs)":[9],"may":[10],"exacerbate":[11],"cognitive":[12,70,116,141,168,186,200],"deterioration":[13],"and":[14,50,58,65,69,78,96,140,184],"biological":[15,51,83,131,182],"aging,":[16],"but":[17],"the":[18,56,79,124,135,194],"biomolecular":[19,102],"mechanisms,":[20],"particularly":[21,146],"those":[22],"driving":[23],"sex-specific":[24],"vulnerability,":[25],"remain":[26],"unclear.":[27],"This":[28],"5-month":[29],"longitudinal":[30],"panel":[31],"study,":[32],"conducted":[33],"among":[34],"76":[35],"healthy":[36],"participants":[37],"aged":[38],"60-69":[39],"in":[40,170],"Jinan,":[41],"China.":[42],"Urinary":[43],"concentrations":[44],"of":[45,82,127,197],"six":[46],"PAHs":[47,111],"were":[48,72],"measured,":[49],"age":[52],"was":[53,85,112],"estimated":[54],"using":[55,74],"Klemera":[57],"Doubal":[59],"method.":[60],"The":[61,104],"associations":[62],"between":[63,137],"individual":[64,97],"combined":[66,119],"PAH":[67,128],"exposures":[68],"function":[71],"examined":[73],"linear":[75],"mixed-effects":[76],"model,":[77],"mediating":[80],"effect":[81],"aging":[84,132,183],"assessed":[86],"by":[87],"mediation":[88],"model.":[89],"Additionally,":[90,159],"lipidomic":[91],"profiling":[92],"including":[93],"lipidome":[94],"clustering":[95,149],"lipids":[98],"helped":[99],"identify":[100],"key":[101,179],"mediators.":[103],"results":[105],"showed":[106],"four":[110],"significantly":[113],"associated":[114],"with":[115,118,188],"decline,":[117,187],"analysis":[121],"further":[122],"indicated":[123],"detrimental":[125],"effects":[126],"mixtures.":[129],"And":[130],"partially":[133,192],"mediated":[134,166],"association":[136],"2-hydroxynaphthalene":[138],"(2-NAP)":[139],"function.":[142],"Key":[143],"lipid":[144,161,175,190],"levels,":[145],"phosphatidylethanolamines":[147],"(PEs)-dominated":[148],"pattern,":[150],"emerged":[151],"as":[152,177],"pivotal":[153],"molecular":[154],"mediator":[155],"shaping":[156],"this":[157],"relationship.":[158],"more":[160],"species,":[162],"notably":[163],"phosphatidylcholines":[164],"(PCs),":[165],"PAHs-induced":[167,185],"decline":[169],"females.":[171],"These":[172],"findings":[173],"elucidate":[174],"levels":[176],"a":[178],"mechanism":[180],"linking":[181],"specific":[189],"alterations":[191],"explaining":[193],"increased":[195],"vulnerability":[196],"females":[198],"decline.":[201]},"counts_by_year":[{"year":2026,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2025-10-19T00:00:00"}
