{"id":"https://openalex.org/W4415319684","doi":"https://doi.org/10.1016/j.arteri.2025.500870","title":"Relaci\u00f3n entre isoformas de apolipoprote\u00edna(a) y niveles de lipoprote\u00edna(a) en pacientes con s\u00edndrome coronario agudo","display_name":"Relaci\u00f3n entre isoformas de apolipoprote\u00edna(a) y niveles de lipoprote\u00edna(a) en pacientes con s\u00edndrome coronario agudo","publication_year":2025,"publication_date":"2025-10-18","ids":{"openalex":"https://openalex.org/W4415319684","doi":"https://doi.org/10.1016/j.arteri.2025.500870","pmid":"https://pubmed.ncbi.nlm.nih.gov/41111030"},"language":"es","primary_location":{"id":"doi:10.1016/j.arteri.2025.500870","doi":"https://doi.org/10.1016/j.arteri.2025.500870","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.arteri.2025.500870","pdf_url":null,"source":{"id":"https://openalex.org/S2898450218","display_name":"Cl\u00ednica e Investigaci\u00f3n en Arteriosclerosis","issn_l":"0214-9168","issn":["0214-9168","1578-1879","1695-4661"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","medline","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cl\u00ednica e Investigaci\u00f3n en Arteriosclerosis","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018593269","display_name":"Rosa Fern\u00e1ndez-Olmo","orcid":"https://orcid.org/0000-0002-3596-0808","observed_orcids":["https://orcid.org/0000-0002-3596-0808"]},"institutions":[{"id":"https://openalex.org/I4210117781","display_name":"Complejo Hospitalario de Ja\u00e9n","ror":"https://ror.org/02ecxgj38","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I158283456","https://openalex.org/I4210117781"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Rosa Fern\u00e1ndez-Olmo","raw_affiliation_strings":["Cardiolog\u00eda, Hospital Universitario de Ja\u00e9n, Ja\u00e9n, Espa\u00f1a. Electronic address: mariarosafernandezolmo@gmail.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiolog\u00eda, Hospital Universitario de Ja\u00e9n, Ja\u00e9n, Espa\u00f1a. Electronic address: mariarosafernandezolmo@gmail.com","institution_ids":["https://openalex.org/I4210117781"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5120050916","display_name":"Jes\u00fas Lara Mariscal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210117781","display_name":"Complejo Hospitalario de Ja\u00e9n","ror":"https://ror.org/02ecxgj38","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I158283456","https://openalex.org/I4210117781"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Jes\u00fas Lara Mariscal","raw_affiliation_strings":["Cardiolog\u00eda, Hospital Universitario de Ja\u00e9n, Ja\u00e9n, Espa\u00f1a"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiolog\u00eda, Hospital Universitario de Ja\u00e9n, Ja\u00e9n, Espa\u00f1a","institution_ids":["https://openalex.org/I4210117781"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027730863","display_name":"Ana Garc\u00eda Ruano","orcid":"https://orcid.org/0000-0001-9207-2455","observed_orcids":["https://orcid.org/0000-0001-9207-2455"]},"institutions":[{"id":"https://openalex.org/I4210117781","display_name":"Complejo Hospitalario de Ja\u00e9n","ror":"https://ror.org/02ecxgj38","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I158283456","https://openalex.org/I4210117781"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Ana Garc\u00eda Ruano","raw_affiliation_strings":["Gen\u00e9tica, Hospital Universitario de Ja\u00e9n, Ja\u00e9n, Espa\u00f1a"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gen\u00e9tica, Hospital Universitario de Ja\u00e9n, Ja\u00e9n, Espa\u00f1a","institution_ids":["https://openalex.org/I4210117781"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004444515","display_name":"Alberto Cordero","orcid":"https://orcid.org/0000-0003-0000-7109","observed_orcids":["https://orcid.org/0000-0003-0000-7109"]},"institutions":[{"id":"https://openalex.org/I4210091477","display_name":"Hospital Universitari Sant Joan D'Alacant","ror":"https://ror.org/00f6kbf47","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210091477"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Alberto Cordero","raw_affiliation_strings":["Cardiolog\u00eda, Hospital Universitario Sant Joan d'Alacant, Sant Joan d'Alacant, Alicante, Espa\u00f1a"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiolog\u00eda, Hospital Universitario Sant Joan d'Alacant, Sant Joan d'Alacant, Alicante, Espa\u00f1a","institution_ids":["https://openalex.org/I4210091477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052918719","display_name":"Juan Manuel Castillo-Casas","orcid":"https://orcid.org/0009-0005-0984-3543","observed_orcids":["https://orcid.org/0009-0005-0984-3543"]},"institutions":[{"id":"https://openalex.org/I191420491","display_name":"Universidad de Ja\u00e9n","ror":"https://ror.org/0122p5f64","country_code":"ES","type":"education","lineage":["https://openalex.org/I191420491"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Juan Manuel Castillo Casas","raw_affiliation_strings":["Grupo de Investigaci\u00f3n Cardiovascular, Departamento de Biolog\u00eda Experimental, Universidad de Ja\u00e9n, Ja\u00e9n, Espa\u00f1a"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Grupo de Investigaci\u00f3n Cardiovascular, Departamento de Biolog\u00eda Experimental, Universidad de Ja\u00e9n, Ja\u00e9n, Espa\u00f1a","institution_ids":["https://openalex.org/I191420491"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081010221","display_name":"Diego Franco","orcid":"https://orcid.org/0000-0002-5669-7164","observed_orcids":["https://orcid.org/0000-0002-5669-7164"]},"institutions":[{"id":"https://openalex.org/I191420491","display_name":"Universidad de Ja\u00e9n","ror":"https://ror.org/0122p5f64","country_code":"ES","type":"education","lineage":["https://openalex.org/I191420491"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Diego Franco","raw_affiliation_strings":["Grupo de Investigaci\u00f3n Cardiovascular, Departamento de Biolog\u00eda Experimental, Universidad de Ja\u00e9n, Ja\u00e9n, Espa\u00f1a"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Grupo de Investigaci\u00f3n Cardiovascular, Departamento de Biolog\u00eda Experimental, Universidad de Ja\u00e9n, Ja\u00e9n, Espa\u00f1a","institution_ids":["https://openalex.org/I191420491"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5018593269"],"corresponding_institution_ids":["https://openalex.org/I4210117781"],"apc_list":{"value":1940,"currency":"USD","value_usd":1940},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"38","issue":"2","first_page":"500870","last_page":"500870"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13430","display_name":"Lipid metabolism and disorders","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/apolipoprotein-a-isoforms","display_name":"apolipoprotein(a) isoforms","score":0.9760000109672546},{"id":"https://openalex.org/keywords/lipoprotein-a","display_name":"lipoprotein(a)","score":0.9610000252723694},{"id":"https://openalex.org/keywords/acute-coronary-syndrome","display_name":"acute coronary syndrome","score":0.949999988079071},{"id":"https://openalex.org/keywords/lpa-gene","display_name":"LPA gene","score":0.9150000214576721},{"id":"https://openalex.org/keywords/cardiovascular-risk-factors","display_name":"cardiovascular risk factors","score":0.6159999966621399}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.729200005531311},{"id":"https://openalex.org/C53345823","wikidata":"https://www.wikidata.org/wiki/Q5531554","display_name":"Gene isoform","level":3,"score":0.6510999798774719},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.6139000058174133},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.521399974822998},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.48019999265670776},{"id":"https://openalex.org/C2777698277","wikidata":"https://www.wikidata.org/wiki/Q266018","display_name":"Acute coronary syndrome","level":3,"score":0.4106000065803528},{"id":"https://openalex.org/C186413461","wikidata":"https://www.wikidata.org/wiki/Q744727","display_name":"Genetic association","level":5,"score":0.3718000054359436},{"id":"https://openalex.org/C117220453","wikidata":"https://www.wikidata.org/wiki/Q5172842","display_name":"Correlation","level":2,"score":0.36579999327659607},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.33329999446868896},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3158999979496002},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.3154999911785126},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.31380000710487366},{"id":"https://openalex.org/C3018906752","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary heart disease","level":2,"score":0.3034000098705292},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.2985000014305115},{"id":"https://openalex.org/C82789193","wikidata":"https://www.wikidata.org/wiki/Q2142611","display_name":"Relative risk","level":3,"score":0.2948000133037567},{"id":"https://openalex.org/C106208931","wikidata":"https://www.wikidata.org/wiki/Q1098876","display_name":"Genome-wide association study","level":5,"score":0.27869999408721924},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.2662999927997589},{"id":"https://openalex.org/C2778213512","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary artery disease","level":2,"score":0.2628999948501587},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.2599000036716461},{"id":"https://openalex.org/C2780648854","wikidata":"https://www.wikidata.org/wiki/Q2745824","display_name":"Immunopathology","level":2,"score":0.2524000108242035},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.2502000033855438}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001054","descriptor_name":"Apolipoproteins A","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015153","descriptor_name":"Blotting, Western","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017270","descriptor_name":"Lipoprotein(a)","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D053241","descriptor_name":"Apoprotein(a)","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D054058","descriptor_name":"Acute Coronary Syndrome","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.arteri.2025.500870","doi":"https://doi.org/10.1016/j.arteri.2025.500870","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.arteri.2025.500870","pdf_url":null,"source":{"id":"https://openalex.org/S2898450218","display_name":"Cl\u00ednica e Investigaci\u00f3n en Arteriosclerosis","issn_l":"0214-9168","issn":["0214-9168","1578-1879","1695-4661"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","medline","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cl\u00ednica e Investigaci\u00f3n en Arteriosclerosis","raw_type":"journal-article"},{"id":"pmid:41111030","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41111030","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9922999739646912,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":6,"referenced_works":["https://openalex.org/W1988877980","https://openalex.org/W3003956143","https://openalex.org/W3092575459","https://openalex.org/W3138852344","https://openalex.org/W4297101339","https://openalex.org/W4317932487"],"related_works":["https://openalex.org/W7126216933","https://openalex.org/W2036005469","https://openalex.org/W2017339175","https://openalex.org/W1982391794","https://openalex.org/W2291555425","https://openalex.org/W3014984938","https://openalex.org/W7132846886","https://openalex.org/W2064683632","https://openalex.org/W2010467286","https://openalex.org/W7064104078"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2025-10-18T00:00:00"}