{"id":"https://openalex.org/W4414929883","doi":"https://doi.org/10.1038/s41598-025-21370-2","title":"Indicators of different outcomes after prolonged weaning","display_name":"Indicators of different outcomes after prolonged weaning","publication_year":2025,"publication_date":"2025-10-08","ids":{"openalex":"https://openalex.org/W4414929883","doi":"https://doi.org/10.1038/s41598-025-21370-2","pmid":"https://pubmed.ncbi.nlm.nih.gov/41062683","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12508469"},"language":"en","primary_location":{"id":"doi:10.1038/s41598-025-21370-2","doi":"https://doi.org/10.1038/s41598-025-21370-2","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-025-21370-2","pdf_url":"https://www.nature.com/articles/s41598-025-21370-2.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41598-025-21370-2.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026864415","display_name":"Julia Dorothea Michels-Zetsche","orcid":"https://orcid.org/0000-0002-7006-7054","observed_orcids":["https://orcid.org/0000-0002-7006-7054"]},"institutions":[{"id":"https://openalex.org/I2802164966","display_name":"University Hospital Heidelberg","ror":"https://ror.org/013czdx64","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802164966"]},{"id":"https://openalex.org/I4210129183","display_name":"German Center for Lung Research","ror":"https://ror.org/03dx11k66","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210129183","https://openalex.org/I4405256427"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Julia D. Michels-Zetsche","raw_affiliation_strings":["Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany. Julia.Michels@med.uni-heidelberg.de","Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany. Julia.Michels@med.uni-heidelberg.de","institution_ids":["https://openalex.org/I2802164966","https://openalex.org/I4210129183"]},{"raw_affiliation_string":"Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany","institution_ids":["https://openalex.org/I2802164966","https://openalex.org/I4210129183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020889097","display_name":"Evelyn R\u00f6ser","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802164966","display_name":"University Hospital Heidelberg","ror":"https://ror.org/013czdx64","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802164966"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Evelyn R\u00f6ser","raw_affiliation_strings":["Department of Thoracic Surgery, Thoraxklinik, University Hospital Heidelberg, Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Thoracic Surgery, Thoraxklinik, University Hospital Heidelberg, Heidelberg, Germany","institution_ids":["https://openalex.org/I2802164966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100282841","display_name":"Hilal Ers\u00f6z","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802164966","display_name":"University Hospital Heidelberg","ror":"https://ror.org/013czdx64","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802164966"]},{"id":"https://openalex.org/I4210129183","display_name":"German Center for Lung Research","ror":"https://ror.org/03dx11k66","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210129183","https://openalex.org/I4405256427"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Hilal Ers\u00f6z","raw_affiliation_strings":["Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany","institution_ids":["https://openalex.org/I2802164966","https://openalex.org/I4210129183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086307663","display_name":"Benjamin Neetz","orcid":"https://orcid.org/0000-0001-8433-9156","observed_orcids":["https://orcid.org/0000-0001-8433-9156"]},"institutions":[{"id":"https://openalex.org/I2802164966","display_name":"University Hospital Heidelberg","ror":"https://ror.org/013czdx64","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802164966"]},{"id":"https://openalex.org/I4210129183","display_name":"German Center for Lung Research","ror":"https://ror.org/03dx11k66","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210129183","https://openalex.org/I4405256427"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Benjamin Neetz","raw_affiliation_strings":["Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany","institution_ids":["https://openalex.org/I2802164966","https://openalex.org/I4210129183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107819948","display_name":"Jana Christina Dahlhoff","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802164966","display_name":"University Hospital Heidelberg","ror":"https://ror.org/013czdx64","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802164966"]},{"id":"https://openalex.org/I4210129183","display_name":"German Center for Lung Research","ror":"https://ror.org/03dx11k66","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210129183","https://openalex.org/I4405256427"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jana C. Dahlhoff","raw_affiliation_strings":["Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany","institution_ids":["https://openalex.org/I2802164966","https://openalex.org/I4210129183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034383087","display_name":"Biljana Joves","orcid":"https://orcid.org/0000-0001-6256-2955","observed_orcids":["https://orcid.org/0000-0001-6256-2955"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Biljana Joves","raw_affiliation_strings":["Department of Pneumology and Critical Care Medicine, SLK Loewenstein Lung Center, Loewenstein, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pneumology and Critical Care Medicine, SLK Loewenstein Lung Center, Loewenstein, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026155191","display_name":"Frederik Trinkmann","orcid":"https://orcid.org/0000-0001-5877-877X","observed_orcids":["https://orcid.org/0000-0001-5877-877X"]},"institutions":[{"id":"https://openalex.org/I2802164966","display_name":"University Hospital Heidelberg","ror":"https://ror.org/013czdx64","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802164966"]},{"id":"https://openalex.org/I4210129183","display_name":"German Center for Lung Research","ror":"https://ror.org/03dx11k66","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210129183","https://openalex.org/I4405256427"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Frederik Trinkmann","raw_affiliation_strings":["Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany","institution_ids":["https://openalex.org/I2802164966","https://openalex.org/I4210129183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104188714","display_name":"Philipp H\u00f6ger","orcid":"https://orcid.org/0009-0006-6637-9166","observed_orcids":["https://orcid.org/0009-0006-6637-9166"]},"institutions":[{"id":"https://openalex.org/I2802164966","display_name":"University Hospital Heidelberg","ror":"https://ror.org/013czdx64","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802164966"]},{"id":"https://openalex.org/I4210129183","display_name":"German Center for Lung Research","ror":"https://ror.org/03dx11k66","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210129183","https://openalex.org/I4405256427"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Philipp H\u00f6ger","raw_affiliation_strings":["Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany","institution_ids":["https://openalex.org/I2802164966","https://openalex.org/I4210129183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051709124","display_name":"Konstantina Kontogianni","orcid":"https://orcid.org/0000-0001-9798-9879","observed_orcids":["https://orcid.org/0000-0001-9798-9879"]},"institutions":[{"id":"https://openalex.org/I2802164966","display_name":"University Hospital Heidelberg","ror":"https://ror.org/013czdx64","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802164966"]},{"id":"https://openalex.org/I4210129183","display_name":"German Center for Lung Research","ror":"https://ror.org/03dx11k66","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210129183","https://openalex.org/I4405256427"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Konstantina Kontogianni","raw_affiliation_strings":["Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany","institution_ids":["https://openalex.org/I2802164966","https://openalex.org/I4210129183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5116417527","display_name":"Cornelia Wei\u00dfmann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802164966","display_name":"University Hospital Heidelberg","ror":"https://ror.org/013czdx64","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802164966"]},{"id":"https://openalex.org/I4210129183","display_name":"German Center for Lung Research","ror":"https://ror.org/03dx11k66","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210129183","https://openalex.org/I4405256427"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Cornelia Weissmann","raw_affiliation_strings":["Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany","institution_ids":["https://openalex.org/I2802164966","https://openalex.org/I4210129183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114538415","display_name":"Max Barre","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802164966","display_name":"University Hospital Heidelberg","ror":"https://ror.org/013czdx64","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802164966"]},{"id":"https://openalex.org/I4210129183","display_name":"German Center for Lung Research","ror":"https://ror.org/03dx11k66","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210129183","https://openalex.org/I4405256427"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Max Barre","raw_affiliation_strings":["Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany","institution_ids":["https://openalex.org/I2802164966","https://openalex.org/I4210129183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068391758","display_name":"Sebastian F\u00e4hndrich","orcid":"https://orcid.org/0000-0002-2277-2672","observed_orcids":["https://orcid.org/0000-0002-2277-2672","https://orcid.org/0000-0001-9910-2063"]},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]},{"id":"https://openalex.org/I2801240073","display_name":"University Medical Center Freiburg","ror":"https://ror.org/03vzbgh69","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2801240073"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sebastian F\u00e4hndrich","raw_affiliation_strings":["Department of Pneumology, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pneumology, University Medical Center Freiburg, University of Freiburg, Freiburg, Germany","institution_ids":["https://openalex.org/I161046081","https://openalex.org/I2801240073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044362647","display_name":"Florian Bornitz","orcid":"https://orcid.org/0000-0001-5235-6621","observed_orcids":["https://orcid.org/0000-0001-5235-6621"]},"institutions":[{"id":"https://openalex.org/I4210153637","display_name":"Asklepios Klinik Barmbek","ror":"https://ror.org/05nyenj39","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210153637"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Florian Bornitz","raw_affiliation_strings":["Department of Pneumology and Internal Intensive Care Medicine, Asklepios Hospital Barmbek, Hamburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pneumology and Internal Intensive Care Medicine, Asklepios Hospital Barmbek, Hamburg, Germany","institution_ids":["https://openalex.org/I4210153637"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Michael M. M\u00fcller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802164966","display_name":"University Hospital Heidelberg","ror":"https://ror.org/013czdx64","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802164966"]},{"id":"https://openalex.org/I4210129183","display_name":"German Center for Lung Research","ror":"https://ror.org/03dx11k66","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210129183","https://openalex.org/I4405256427"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Michael M. M\u00fcller","raw_affiliation_strings":["Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany","institution_ids":["https://openalex.org/I2802164966","https://openalex.org/I4210129183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024585720","display_name":"Felix J.F. Herth","orcid":"https://orcid.org/0000-0002-7638-2506","observed_orcids":["https://orcid.org/0000-0002-7638-2506"]},"institutions":[{"id":"https://openalex.org/I2802164966","display_name":"University Hospital Heidelberg","ror":"https://ror.org/013czdx64","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802164966"]},{"id":"https://openalex.org/I4210129183","display_name":"German Center for Lung Research","ror":"https://ror.org/03dx11k66","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210129183","https://openalex.org/I4405256427"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Felix J. F. Herth","raw_affiliation_strings":["Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany","institution_ids":["https://openalex.org/I2802164966","https://openalex.org/I4210129183"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075891067","display_name":"Franziska Christina Trudzinski","orcid":"https://orcid.org/0000-0002-0980-7586","observed_orcids":["https://orcid.org/0000-0002-0980-7586"]},"institutions":[{"id":"https://openalex.org/I2802164966","display_name":"University Hospital Heidelberg","ror":"https://ror.org/013czdx64","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2802164966"]},{"id":"https://openalex.org/I4210129183","display_name":"German Center for Lung Research","ror":"https://ror.org/03dx11k66","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210129183","https://openalex.org/I4405256427"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Franziska C. Trudzinski","raw_affiliation_strings":["Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pneumology and Critical Care, Thoraxklinik, University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), R\u00f6ntgenstrasse 1, 69126, Heidelberg, Germany","institution_ids":["https://openalex.org/I2802164966","https://openalex.org/I4210129183"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5026864415"],"corresponding_institution_ids":["https://openalex.org/I2802164966","https://openalex.org/I4210129183"],"apc_list":{"value":2690,"currency":"USD","value_usd":2690},"apc_paid":{"value":2690,"currency":"USD","value_usd":2690},"fwci":2.839,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.89682048,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":98},"biblio":{"volume":"15","issue":"1","first_page":"35044","last_page":"35044"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11681","display_name":"Nosocomial Infections in ICU","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prolonged-weaning","display_name":"prolonged weaning","score":0.8799999952316284},{"id":"https://openalex.org/keywords/weaning-failure","display_name":"weaning failure","score":0.593999981880188},{"id":"https://openalex.org/keywords/non-invasive-ventilation","display_name":"non-invasive ventilation","score":0.7599999904632568},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.4189999997615814},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.8320000171661377},{"id":"https://openalex.org/keywords/kidney-failure","display_name":"renal failure","score":0.7689999938011169},{"id":"https://openalex.org/keywords/critical-illness-polyneuropathy","display_name":"critical illness polyneuropathy","score":0.9440000057220459},{"id":"https://openalex.org/keywords/chronic-obstructive-pulmonary-disease","display_name":"chronic obstructive pulmonary disease","score":0.7450000047683716},{"id":"https://openalex.org/keywords/hospital-acquired-pneumonia","display_name":"nosocomial pneumonia","score":0.8289999961853027},{"id":"https://openalex.org/keywords/cancer","display_name":"cancer","score":0.6790000200271606},{"id":"https://openalex.org/keywords/neuromuscular-disorders","display_name":"neuromuscular disorders","score":0.7440000176429749},{"id":"https://openalex.org/keywords/length-of-hospital-stay","display_name":"length of hospital stay","score":0.5820000171661377}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.914900004863739},{"id":"https://openalex.org/C2780655333","wikidata":"https://www.wikidata.org/wiki/Q333203","display_name":"Weaning","level":2,"score":0.8550000190734863},{"id":"https://openalex.org/C2777914695","wikidata":"https://www.wikidata.org/wiki/Q12192","display_name":"Pneumonia","level":2,"score":0.6389999985694885},{"id":"https://openalex.org/C2779399171","wikidata":"https://www.wikidata.org/wiki/Q1483951","display_name":"Malignancy","level":2,"score":0.5691999793052673},{"id":"https://openalex.org/C2777080012","wikidata":"https://www.wikidata.org/wiki/Q3766250","display_name":"Mechanical ventilation","level":2,"score":0.4860000014305115},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4302999973297119},{"id":"https://openalex.org/C137627325","wikidata":"https://www.wikidata.org/wiki/Q156318","display_name":"Etiology","level":2,"score":0.4268999993801117},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3962000012397766},{"id":"https://openalex.org/C2775904088","wikidata":"https://www.wikidata.org/wiki/Q17152779","display_name":"Intermittent mandatory ventilation","level":3,"score":0.364300012588501},{"id":"https://openalex.org/C2776780178","wikidata":"https://www.wikidata.org/wiki/Q199804","display_name":"COPD","level":2,"score":0.3587000072002411},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.33009999990463257},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.31769999861717224},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.2867000102996826},{"id":"https://openalex.org/C200457457","wikidata":"https://www.wikidata.org/wiki/Q584049","display_name":"Ventilation (architecture)","level":2,"score":0.2818000018596649},{"id":"https://openalex.org/C3018023364","wikidata":"https://www.wikidata.org/wiki/Q425265","display_name":"Significant difference","level":2,"score":0.2660999894142151},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.25929999351501465},{"id":"https://openalex.org/C30036603","wikidata":"https://www.wikidata.org/wiki/Q17125150","display_name":"Severity of illness","level":2,"score":0.25519999861717224}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007902","descriptor_name":"Length of Stay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015300","descriptor_name":"Ventilator Weaning","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063087","descriptor_name":"Noninvasive Ventilation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1038/s41598-025-21370-2","doi":"https://doi.org/10.1038/s41598-025-21370-2","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-025-21370-2","pdf_url":"https://www.nature.com/articles/s41598-025-21370-2.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:11316472","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12508469","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:41062683","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41062683","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific reports","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12508469","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12508469/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sci Rep","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:2f1c4a1bdd384a54b29f5726d46085af","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/2f1c4a1bdd384a54b29f5726d46085af","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scientific Reports, Vol 15, Iss 1, Pp 1-9 (2025)","raw_type":"article"},{"id":"pmh:oai:freidok.uni-freiburg.de:273347","doi":null,"is_oa":false,"landing_page_url":"https://freidok.uni-freiburg.de/data/273347","pdf_url":null,"source":{"id":"https://openalex.org/S4306401057","display_name":"FreiDok plus (Universit\u00e4tsbibliothek Freiburg)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I161046081","host_organization_name":"University of Freiburg","host_organization_lineage":["https://openalex.org/I161046081"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scientific reports. - 15, 1 (2025) , 35044, ISSN: 2045-2322","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/s41598-025-21370-2","doi":"https://doi.org/10.1038/s41598-025-21370-2","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-025-21370-2","pdf_url":"https://www.nature.com/articles/s41598-025-21370-2.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320330130","display_name":"Universit\u00e4tsklinikum Heidelberg","ror":"https://ror.org/013czdx64"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4414929883.pdf","grobid_xml":"https://content.openalex.org/works/W4414929883.grobid-xml"},"referenced_works_count":15,"referenced_works":["https://openalex.org/W2018505465","https://openalex.org/W2142104245","https://openalex.org/W2520124172","https://openalex.org/W2536728119","https://openalex.org/W2888030176","https://openalex.org/W3009058433","https://openalex.org/W3012385736","https://openalex.org/W3111262436","https://openalex.org/W4246633514","https://openalex.org/W4292148870","https://openalex.org/W4317677560","https://openalex.org/W4361274163","https://openalex.org/W4386154260","https://openalex.org/W4391281778","https://openalex.org/W4391539966"],"related_works":["https://openalex.org/W4404099901","https://openalex.org/W4312693710","https://openalex.org/W3214772864","https://openalex.org/W4210580581","https://openalex.org/W3012385736","https://openalex.org/W4293147705","https://openalex.org/W2012229524","https://openalex.org/W4319461340","https://openalex.org/W2074351157","https://openalex.org/W2318014919"],"abstract_inverted_index":{"Abstract":[0],"The":[1,67,259],"outcomes":[2],"of":[3,22,69,91,132,158,164,195,200,214,232,256,287,303,317,332],"prolonged":[4,32,333],"weaning":[5,9,14,33,82,297,322],"in":[6,74,81,109,319,330],"a":[7,123,204],"specialist":[8],"centre":[10],"range":[11],"from":[12,37,262],"successful":[13],"to":[15,19,40,189],"death.":[16],"We":[17,26],"aimed":[18],"identify":[20],"indicators":[21,255,261,294],"the":[23,75,212,288,320],"different":[24],"outcomes.":[25,290],"analysed":[27],"915":[28],"patients":[29,174,329],"who":[30],"underwent":[31],"at":[34,98],"Thoraxklinik":[35],"Heidelberg":[36],"Dec.":[38,41],"2008":[39],"2023.":[42],"73.2%":[43],"were":[44,58,94,135,186,198,254,265],"successfully":[45],"weaned,":[46],"36.1%":[47],"without":[48],"(3a)":[49],"and":[50,63,93,117,129,168,179,227,249,273,283,299,324],"37.1%":[51],"with":[52,60,78,122,175,203],"subsequent":[53],"non-invasive":[54],"ventilation":[55],"(3b).":[56],"20.2%":[57],"discharged":[59,77],"IMV":[61,92,106,159,202,215],"(3cI)":[62],"6.6%":[64],"died":[65],"(3cII).":[66],"length":[68,316],"stay":[70,318],"was":[71,111],"significantly":[72,112],"longer":[73],"group":[76],"IMV.":[79],"Patients":[80],"category":[83,133,196,257],"3a":[84],"had":[85],"fewer":[86],"comorbidities,":[87],"also":[88],"as":[89,211],"cause":[90,157,213],"less":[95,187],"obese":[96],"(each":[97],"least":[99],"OR":[100,140,184],"\u2264":[101,104,239],"0.6,":[102],"p":[103,149],"0.02).":[105],"before":[107],"admission":[108],"days":[110],"shorter,":[113],"FiO":[114],"2":[115,119,146,154,242],"higher":[116,152],"pCO":[118,153],"lower,":[120],"although":[121],"weak":[124,205],"effect":[125,206],"(OR":[126,147,155,161,166,171,177,207,216,221,225,229,235,243,247,252],"between":[127,281],"1.014":[128],"0.971).":[130],"Indicators":[131,194],"3b":[134],"younger":[136],"age":[137],"(weak":[138],"effect,":[139],"0.977),":[141],"BMI":[142,238],"\u2265":[143],"30":[144],"kg/m":[145,241],"2.470,":[148],"<":[150],"0,001),":[151],"1.044),":[156],"AECOPD":[160],"2.803),":[162],"pre-diagnosis":[163],"COPD":[165],"2.073)":[167],"nosocomial":[169,233],"pneumonia":[170,234],"1.857),":[172],"whereas":[173],"malignancy":[176,251],"0.438)":[178],"CIP":[180,228],"(critical":[181],"illness":[182],"polyneuropathy,":[183],"0.523)":[185],"likely":[188],"fall":[190],"into":[191,267],"this":[192],"category.":[193],"3cI":[197],"duration":[199],"previous":[201],"1.006),":[208],"neuromuscular":[209],"disease":[210,220],"6.023),":[217],"restrictive":[218],"thoracic":[219],"2.330),":[222],"renal":[223,245],"insufficiency":[224,246],"1.977)":[226],"1.744),":[230],"absence":[231],"0.366).":[236],"Only":[237],"20":[240],"3.611),":[244],"1.253)":[248],"pre-diagnosed":[250],"1.785)":[253],"3cII.":[258],"relevant":[260],"multivariate":[263],"analyses":[264],"transferred":[266],"ROC":[268],"(receiver":[269],"operating":[270],"characteristic)":[271],"curves":[272],"show":[274],"an":[275,300],"acceptable":[276],"AUC":[277],"(area":[278],"under":[279],"curve)":[280],"0.72":[282],"0.79":[284],"for":[285,295,327],"each":[286,296,304],"four":[289],"There":[291],"are":[292],"specific":[293],"outcome":[298],"early":[301],"assessment":[302],"patient\u2019s":[305],"individual":[306],"risk":[307],"profile":[308],"can":[309],"help":[310],"plan":[311],"further":[312],"outpatient":[313],"care,":[314],"shorten":[315],"ventilator":[321],"unit":[323],"generate":[325],"capacities":[326],"other":[328],"need":[331],"weaning.":[334]},"counts_by_year":[{"year":2026,"cited_by_count":5}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2025-10-10T00:00:00"}