{"id":"https://openalex.org/W4414848739","doi":"https://doi.org/10.1038/s41929-025-01418-2","title":"Enantioselective radical dearomative conjugate amination enabled by Co(II)-based metalloradical catalysis","display_name":"Enantioselective radical dearomative conjugate amination enabled by Co(II)-based metalloradical catalysis","publication_year":2025,"publication_date":"2025-10-06","ids":{"openalex":"https://openalex.org/W4414848739","doi":"https://doi.org/10.1038/s41929-025-01418-2","pmid":"https://pubmed.ncbi.nlm.nih.gov/41113279","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12530439"},"language":"en","primary_location":{"id":"doi:10.1038/s41929-025-01418-2","doi":"https://doi.org/10.1038/s41929-025-01418-2","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s41929-025-01418-2","pdf_url":null,"source":{"id":"https://openalex.org/S4210229375","display_name":"Nature Catalysis","issn_l":"2520-1158","issn":["2520-1158"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","norway-2","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Catalysis","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12530439/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101895300","display_name":"Pan Xu","orcid":"https://orcid.org/0000-0002-3433-3378","observed_orcids":["https://orcid.org/0000-0002-3433-3378"]},"institutions":[{"id":"https://openalex.org/I103531236","display_name":"Boston College","ror":"https://ror.org/02n2fzt79","country_code":"US","type":"education","lineage":["https://openalex.org/I103531236"]},{"id":"https://openalex.org/I76569877","display_name":"Southeast University","ror":"https://ror.org/04ct4d772","country_code":"CN","type":"education","lineage":["https://openalex.org/I76569877"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Pan Xu","raw_affiliation_strings":["Department of Chemistry, Merkert Chemistry Center, Boston College; Chestnut Hill, Massachusetts 02467, United States","School of Chemistry and Chemical Engineering, Southeast University; Nanjing 211189, P. R. China","Department of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, MA, USA","School of Chemistry and Chemical Engineering, Southeast University, Nanjing, China"],"raw_orcid":"https://orcid.org/0000-0002-3433-3378","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Merkert Chemistry Center, Boston College; Chestnut Hill, Massachusetts 02467, United States","institution_ids":["https://openalex.org/I103531236"]},{"raw_affiliation_string":"School of Chemistry and Chemical Engineering, Southeast University; Nanjing 211189, P. R. China","institution_ids":["https://openalex.org/I76569877"]},{"raw_affiliation_string":"Department of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, MA, USA","institution_ids":["https://openalex.org/I103531236"]},{"raw_affiliation_string":"School of Chemistry and Chemical Engineering, Southeast University, Nanjing, China","institution_ids":["https://openalex.org/I76569877"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076751826","display_name":"Duo\u2010Sheng Wang","orcid":"https://orcid.org/0000-0002-3519-2386","observed_orcids":["https://orcid.org/0000-0002-3519-2386"]},"institutions":[{"id":"https://openalex.org/I103531236","display_name":"Boston College","ror":"https://ror.org/02n2fzt79","country_code":"US","type":"education","lineage":["https://openalex.org/I103531236"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Duo-Sheng Wang","raw_affiliation_strings":["Department of Chemistry, Merkert Chemistry Center, Boston College; Chestnut Hill, Massachusetts 02467, United States","Department of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-3519-2386","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Merkert Chemistry Center, Boston College; Chestnut Hill, Massachusetts 02467, United States","institution_ids":["https://openalex.org/I103531236"]},{"raw_affiliation_string":"Department of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, MA, USA","institution_ids":["https://openalex.org/I103531236"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Zhenyu Zhu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I103531236","display_name":"Boston College","ror":"https://ror.org/02n2fzt79","country_code":"US","type":"education","lineage":["https://openalex.org/I103531236"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhenyu Zhu","raw_affiliation_strings":["Department of Chemistry, Merkert Chemistry Center, Boston College; Chestnut Hill, Massachusetts 02467, United States","Department of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Merkert Chemistry Center, Boston College; Chestnut Hill, Massachusetts 02467, United States","institution_ids":["https://openalex.org/I103531236"]},{"raw_affiliation_string":"Department of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, MA, USA","institution_ids":["https://openalex.org/I103531236"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083317667","display_name":"X. Peter Zhang","orcid":"https://orcid.org/0000-0001-7574-8409","observed_orcids":["https://orcid.org/0000-0001-7574-8409","https://orcid.org/0000-0001-9811-0221"]},"institutions":[{"id":"https://openalex.org/I103531236","display_name":"Boston College","ror":"https://ror.org/02n2fzt79","country_code":"US","type":"education","lineage":["https://openalex.org/I103531236"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"X. Peter Zhang","raw_affiliation_strings":["Department of Chemistry, Merkert Chemistry Center, Boston College; Chestnut Hill, Massachusetts 02467, United States","Department of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, MA, USA"],"raw_orcid":"https://orcid.org/0000-0001-7574-8409","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Merkert Chemistry Center, Boston College; Chestnut Hill, Massachusetts 02467, United States","institution_ids":["https://openalex.org/I103531236"]},{"raw_affiliation_string":"Department of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, MA, USA","institution_ids":["https://openalex.org/I103531236"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5083317667"],"corresponding_institution_ids":["https://openalex.org/I103531236"],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":null,"fwci":1.5821,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.79203795,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"8","issue":"10","first_page":"1051","last_page":"1061"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10701","display_name":"Radical Photochemical Reactions","score":0.7612000107765198,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10701","display_name":"Radical Photochemical Reactions","score":0.7612000107765198,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10013","display_name":"Asymmetric Synthesis and Catalysis","score":0.18529999256134033,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12251","display_name":"Synthesis and Catalytic Reactions","score":0.017899999395012856,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/regioselectivity","display_name":"regioselectivity","score":0.875},{"id":"https://openalex.org/keywords/c-n-bond-formation","display_name":"C\u2013N bond formation","score":0.8230000138282776},{"id":"https://openalex.org/keywords/aryl-azides","display_name":"aryl azides","score":0.8009999990463257},{"id":"https://openalex.org/keywords/4-vinylphenol","display_name":"4-vinylphenol","score":0.9639999866485596},{"id":"https://openalex.org/keywords/hydrogen-abstraction","display_name":"hydrogen abstraction","score":0.7329999804496765},{"id":"https://openalex.org/keywords/1-6-addition","display_name":"1,6-addition","score":0.8960000276565552},{"id":"https://openalex.org/keywords/quinone-methides","display_name":"quinone methides","score":0.7789999842643738},{"id":"https://openalex.org/keywords/stereoselective-synthesis","display_name":"stereoselective synthesis","score":0.6790000200271606}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8133000135421753},{"id":"https://openalex.org/C198503264","wikidata":"https://www.wikidata.org/wiki/Q471635","display_name":"Amination","level":3,"score":0.8094000220298767},{"id":"https://openalex.org/C59759590","wikidata":"https://www.wikidata.org/wiki/Q2275927","display_name":"Regioselectivity","level":3,"score":0.7692000269889832},{"id":"https://openalex.org/C146686406","wikidata":"https://www.wikidata.org/wiki/Q898628","display_name":"Enantioselective synthesis","level":3,"score":0.7576000094413757},{"id":"https://openalex.org/C70050531","wikidata":"https://www.wikidata.org/wiki/Q899089","display_name":"Delocalized electron","level":2,"score":0.7232999801635742},{"id":"https://openalex.org/C120095180","wikidata":"https://www.wikidata.org/wiki/Q2695010","display_name":"Allylic rearrangement","level":3,"score":0.6694999933242798},{"id":"https://openalex.org/C139066938","wikidata":"https://www.wikidata.org/wiki/Q185056","display_name":"Radical","level":2,"score":0.6534000039100647},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.5264999866485596},{"id":"https://openalex.org/C2777389692","wikidata":"https://www.wikidata.org/wiki/Q4802699","display_name":"Aryl radical","level":4,"score":0.45159998536109924},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.4474000036716461},{"id":"https://openalex.org/C2781076698","wikidata":"https://www.wikidata.org/wiki/Q718074","display_name":"Aryl","level":3,"score":0.4154999852180481},{"id":"https://openalex.org/C535685238","wikidata":"https://www.wikidata.org/wiki/Q1153832","display_name":"Organic synthesis","level":3,"score":0.37599998712539673},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.37279999256134033},{"id":"https://openalex.org/C112613896","wikidata":"https://www.wikidata.org/wiki/Q898370","display_name":"Conjugated system","level":3,"score":0.3190000057220459},{"id":"https://openalex.org/C2776254738","wikidata":"https://www.wikidata.org/wiki/Q81406","display_name":"Alkene","level":3,"score":0.30640000104904175},{"id":"https://openalex.org/C66972969","wikidata":"https://www.wikidata.org/wiki/Q898995","display_name":"Organocatalysis","level":4,"score":0.29980000853538513},{"id":"https://openalex.org/C2778544067","wikidata":"https://www.wikidata.org/wiki/Q409141","display_name":"Aziridine","level":3,"score":0.2930000126361847},{"id":"https://openalex.org/C197336794","wikidata":"https://www.wikidata.org/wiki/Q5161150","display_name":"Conjugate","level":2,"score":0.2770000100135803},{"id":"https://openalex.org/C20327893","wikidata":"https://www.wikidata.org/wiki/Q7280479","display_name":"Radical cyclization","level":2,"score":0.2752000093460083},{"id":"https://openalex.org/C129694887","wikidata":"https://www.wikidata.org/wiki/Q47455153","display_name":"Stereoisomerism","level":3,"score":0.27309998869895935},{"id":"https://openalex.org/C502130503","wikidata":"https://www.wikidata.org/wiki/Q1089","display_name":"Palladium","level":3,"score":0.27090001106262207}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1038/s41929-025-01418-2","doi":"https://doi.org/10.1038/s41929-025-01418-2","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s41929-025-01418-2","pdf_url":null,"source":{"id":"https://openalex.org/S4210229375","display_name":"Nature Catalysis","issn_l":"2520-1158","issn":["2520-1158"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","norway-2","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Catalysis","raw_type":"journal-article"},{"id":"pmid:41113279","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41113279","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature catalysis","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12530439","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12530439/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Nat Catal","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:12530439","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12530439/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Nat Catal","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1482848736","display_name":"CryoProbe-enabled Bruker AVANCE NEO 500 MHz NMR Spectrometer","funder_award_id":"S10OD026910","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2706412694","display_name":"Stereoselective Radical Processes for C-H Alkylation and Amination","funder_award_id":"R01GM132471","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G3212165152","display_name":"Bruker D8 VENTURE Diffractometer","funder_award_id":"1s10od030360-01a1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4033749864","display_name":"Metalloradical Catalysis for Selective Radical Reactions","funder_award_id":"2154885","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G4162508552","display_name":"Catalytic Processes for Stereoselective Radical Cyclization Reactions","funder_award_id":"R01GM102554","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G8218372101","display_name":null,"funder_award_id":"R01-GM132471","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G8523240924","display_name":null,"funder_award_id":"R01-GM102554","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G9000861741","display_name":"Catalytic Radical Processes for Stereoselective Chemical Synthesis","funder_award_id":"R35GM156311","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320306085","display_name":"U.S. Department of Health and Human Services","ror":"https://ror.org/033jnv181"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W1882007441","https://openalex.org/W2058140411","https://openalex.org/W2069853509","https://openalex.org/W2073241080","https://openalex.org/W2095404450","https://openalex.org/W2098083208","https://openalex.org/W2116933801","https://openalex.org/W2137276014","https://openalex.org/W2153402402","https://openalex.org/W2274887980","https://openalex.org/W2560768297","https://openalex.org/W2742826843","https://openalex.org/W2746830903","https://openalex.org/W2771681521","https://openalex.org/W2795687764","https://openalex.org/W2911689993","https://openalex.org/W2914061402","https://openalex.org/W2946687115","https://openalex.org/W2947399721","https://openalex.org/W2951435261","https://openalex.org/W2957804426","https://openalex.org/W2972038326","https://openalex.org/W2981389967","https://openalex.org/W2982360177","https://openalex.org/W3007373114","https://openalex.org/W3093215876","https://openalex.org/W3109409400","https://openalex.org/W3126036341","https://openalex.org/W3155137388","https://openalex.org/W3176445847","https://openalex.org/W3215384663","https://openalex.org/W4210588651","https://openalex.org/W4211144134","https://openalex.org/W4220816678","https://openalex.org/W4230004918","https://openalex.org/W4310141939","https://openalex.org/W4315707375","https://openalex.org/W4320486476","https://openalex.org/W4328049616","https://openalex.org/W4361269323","https://openalex.org/W4362458267","https://openalex.org/W4382653330","https://openalex.org/W4386498777","https://openalex.org/W4387540585","https://openalex.org/W4389077124","https://openalex.org/W4392761980","https://openalex.org/W4399803159"],"related_works":["https://openalex.org/W4409662818","https://openalex.org/W4210379788","https://openalex.org/W4315707375","https://openalex.org/W3109409400","https://openalex.org/W1954803579","https://openalex.org/W2799605355","https://openalex.org/W2067626193","https://openalex.org/W4243579525","https://openalex.org/W3147545272","https://openalex.org/W2666100349"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":6}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2025-10-10T00:00:00"}