{"id":"https://openalex.org/W4414741069","doi":"https://doi.org/10.1093/clinchem/hvaf086.144","title":"A-148 Implementation of YOLO11-RBC Deep Learning Framework for Advanced Erythrocyte Morphological Analysis","display_name":"A-148 Implementation of YOLO11-RBC Deep Learning Framework for Advanced Erythrocyte Morphological Analysis","publication_year":2025,"publication_date":"2025-10-01","ids":{"openalex":"https://openalex.org/W4414741069","doi":"https://doi.org/10.1093/clinchem/hvaf086.144"},"language":"en","primary_location":{"id":"doi:10.1093/clinchem/hvaf086.144","doi":"https://doi.org/10.1093/clinchem/hvaf086.144","is_oa":true,"landing_page_url":"https://doi.org/10.1093/clinchem/hvaf086.144","pdf_url":"https://academic.oup.com/clinchem/article-pdf/71/Supplement_1/hvaf086.144/64461986/hvaf086.144.pdf","source":{"id":"https://openalex.org/S139212996","display_name":"Clinical Chemistry","issn_l":"0009-9147","issn":["0009-9147","1530-8561"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320272","host_organization_name":"American Association for Clinical Chemistry","host_organization_lineage":["https://openalex.org/P4310320272"],"host_organization_lineage_names":["American Association for Clinical Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Chemistry","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/clinchem/article-pdf/71/Supplement_1/hvaf086.144/64461986/hvaf086.144.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5119824478","display_name":"Louyin Zhu","orcid":"https://orcid.org/0000-0003-1685-7968","observed_orcids":["https://orcid.org/0000-0003-1685-7968"]},"institutions":[{"id":"https://openalex.org/I4210158983","display_name":"Mindray (China)","ror":"https://ror.org/04yfe8169","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210158983"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Louyin Zhu","raw_affiliation_strings":["Mindray , Shenzhen ,","Mindray, Shenzhen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mindray , Shenzhen ,","institution_ids":["https://openalex.org/I4210158983"]},{"raw_affiliation_string":"Mindray, Shenzhen, China","institution_ids":["https://openalex.org/I4210158983"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100389794","display_name":"Yan Liu","orcid":"https://orcid.org/0000-0003-0906-2606","observed_orcids":["https://orcid.org/0000-0003-0906-2606"]},"institutions":[{"id":"https://openalex.org/I4210158983","display_name":"Mindray (China)","ror":"https://ror.org/04yfe8169","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210158983"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yan Liu","raw_affiliation_strings":["Mindray , Shenzhen ,","Mindray, Shenzhen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mindray , Shenzhen ,","institution_ids":["https://openalex.org/I4210158983"]},{"raw_affiliation_string":"Mindray, Shenzhen, China","institution_ids":["https://openalex.org/I4210158983"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089031306","display_name":"Bin Zhao","orcid":"https://orcid.org/0000-0002-1501-5980","observed_orcids":["https://orcid.org/0000-0002-1501-5980"]},"institutions":[{"id":"https://openalex.org/I4210158983","display_name":"Mindray (China)","ror":"https://ror.org/04yfe8169","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210158983"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bin Zhao","raw_affiliation_strings":["Clinical Department (IVD), Shenzhen Mindray Bio-Medical Electronics Co., Ltd , Shenzhen ,","Clinical Department (IVD), Shenzhen Mindray Bio-Medical Electronics Co., Ltd, Shenzhen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Department (IVD), Shenzhen Mindray Bio-Medical Electronics Co., Ltd , Shenzhen ,","institution_ids":["https://openalex.org/I4210158983"]},{"raw_affiliation_string":"Clinical Department (IVD), Shenzhen Mindray Bio-Medical Electronics Co., Ltd, Shenzhen, China","institution_ids":["https://openalex.org/I4210158983"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101867461","display_name":"Jingxian Zhang","orcid":"https://orcid.org/0009-0008-0368-2365","observed_orcids":["https://orcid.org/0009-0008-0368-2365","https://orcid.org/0009-0001-1717-3835"]},"institutions":[{"id":"https://openalex.org/I4210158983","display_name":"Mindray (China)","ror":"https://ror.org/04yfe8169","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210158983"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jingxian Zhang","raw_affiliation_strings":["Clinical Department (IVD), Shenzhen Mindray Bio-Medical Electronics Co., Ltd , Shenzhen ,","Clinical Department (IVD), Shenzhen Mindray Bio-Medical Electronics Co., Ltd, Shenzhen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Department (IVD), Shenzhen Mindray Bio-Medical Electronics Co., Ltd , Shenzhen ,","institution_ids":["https://openalex.org/I4210158983"]},{"raw_affiliation_string":"Clinical Department (IVD), Shenzhen Mindray Bio-Medical Electronics Co., Ltd, Shenzhen, China","institution_ids":["https://openalex.org/I4210158983"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076387467","display_name":"Junxun Li","orcid":"https://orcid.org/0000-0003-0636-9506","observed_orcids":["https://orcid.org/0000-0003-0636-9506"]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210128921","display_name":"The First Affiliated Hospital, Sun Yat-sen University","ror":"https://ror.org/037p24858","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210128921"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junxun Li","raw_affiliation_strings":["The First Affiliated Hospital, Sun Yat-sen University , Guangzhou ,","The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The First Affiliated Hospital, Sun Yat-sen University , Guangzhou ,","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210128921"]},{"raw_affiliation_string":"The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China","institution_ids":["https://openalex.org/I4210128921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102193863","display_name":"Qi Cai","orcid":"https://orcid.org/0009-0000-6639-1727","observed_orcids":["https://orcid.org/0009-0000-6639-1727"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qi Cai","raw_affiliation_strings":["Ruijin Hospital, Shanghai Jiaotong University School of Medicine , Shanghai ,","Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ruijin Hospital, Shanghai Jiaotong University School of Medicine , Shanghai ,","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]},{"raw_affiliation_string":"Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hui Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210122896","display_name":"Yunnan Institute of Parasitic Diseases","ror":"https://ror.org/03sasjr79","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210122896"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hui Liu","raw_affiliation_strings":["Yunnan Institute of Parasitic Diseases , Pu'er ,","Yunnan Institute of Parasitic Diseases, Pu'er, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yunnan Institute of Parasitic Diseases , Pu'er ,","institution_ids":["https://openalex.org/I4210122896"]},{"raw_affiliation_string":"Yunnan Institute of Parasitic Diseases, Pu'er, China","institution_ids":["https://openalex.org/I4210122896"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100403511","display_name":"Fan Zhang","orcid":"https://orcid.org/0000-0002-8525-4514","observed_orcids":["https://orcid.org/0000-0002-8525-4514"]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210128921","display_name":"The First Affiliated Hospital, Sun Yat-sen University","ror":"https://ror.org/037p24858","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210128921"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fan Zhang","raw_affiliation_strings":["The First Affiliated Hospital, Sun Yat-sen University , Guangzhou ,","The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The First Affiliated Hospital, Sun Yat-sen University , Guangzhou ,","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210128921"]},{"raw_affiliation_string":"The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China","institution_ids":["https://openalex.org/I4210128921"]}]},{"author_position":"last","author":{"id":null,"display_name":"Bo Ye","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210158983","display_name":"Mindray (China)","ror":"https://ror.org/04yfe8169","country_code":"CN","type":"company","lineage":["https://openalex.org/I4210158983"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bo Ye","raw_affiliation_strings":["Clinical Department (IVD), Shenzhen Mindray Bio-Medical Electronics Co., Ltd , Shenzhen ,","Clinical Department (IVD), Shenzhen Mindray Bio-Medical Electronics Co., Ltd, Shenzhen, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Department (IVD), Shenzhen Mindray Bio-Medical Electronics Co., Ltd , Shenzhen ,","institution_ids":["https://openalex.org/I4210158983"]},{"raw_affiliation_string":"Clinical Department (IVD), Shenzhen Mindray Bio-Medical Electronics Co., Ltd, Shenzhen, China","institution_ids":["https://openalex.org/I4210158983"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4636,"currency":"USD","value_usd":4636},"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"71","issue":"Supplement_1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11721","display_name":"Blood properties and coagulation","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/red-blood-cell-morphology","display_name":"erythrocyte morphology","score":0.8799999952316284},{"id":"https://openalex.org/keywords/object-detection","display_name":"object detection","score":0.9419999718666077},{"id":"https://openalex.org/keywords/blood-smear-images","display_name":"blood smear images","score":0.6079999804496765},{"id":"https://openalex.org/keywords/schistocytes","display_name":"schistocytes","score":0.7440000176429749},{"id":"https://openalex.org/keywords/target-cells","display_name":"target cells","score":0.45100000500679016},{"id":"https://openalex.org/keywords/echinocytes","display_name":"echinocytes","score":0.550000011920929},{"id":"https://openalex.org/keywords/rouleaux-formation","display_name":"rouleaux formation","score":0.621999979019165},{"id":"https://openalex.org/keywords/agglutination","display_name":"agglutination","score":0.8169999718666077},{"id":"https://openalex.org/keywords/class-imbalance","display_name":"class imbalance","score":0.5239999890327454},{"id":"https://openalex.org/keywords/data-augmentation","display_name":"data augmentation","score":0.753000020980835},{"id":"https://openalex.org/keywords/sickle-cell-disease","display_name":"sickle cell disease","score":0.5239999890327454}],"concepts":[{"id":"https://openalex.org/C3017819844","wikidata":"https://www.wikidata.org/wiki/Q886475","display_name":"Blood smear","level":3,"score":0.652999997138977},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5695000290870667},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.5432999730110168},{"id":"https://openalex.org/C2776557347","wikidata":"https://www.wikidata.org/wiki/Q37187","display_name":"Red blood cell","level":2,"score":0.5202000141143799},{"id":"https://openalex.org/C2909954168","wikidata":"https://www.wikidata.org/wiki/Q860755","display_name":"Digital image analysis","level":2,"score":0.4156000018119812},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4124000072479248},{"id":"https://openalex.org/C42781572","wikidata":"https://www.wikidata.org/wiki/Q1250322","display_name":"Digital image","level":4,"score":0.39649999141693115},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.37790000438690186},{"id":"https://openalex.org/C2779979121","wikidata":"https://www.wikidata.org/wiki/Q211709","display_name":"Blood cell","level":2,"score":0.3538999855518341},{"id":"https://openalex.org/C2776151529","wikidata":"https://www.wikidata.org/wiki/Q3045304","display_name":"Object detection","level":3,"score":0.34529998898506165},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3199999928474426},{"id":"https://openalex.org/C19210678","wikidata":"https://www.wikidata.org/wiki/Q672718","display_name":"Basophilic","level":2,"score":0.3190999925136566},{"id":"https://openalex.org/C499950583","wikidata":"https://www.wikidata.org/wiki/Q183252","display_name":"Morphology (biology)","level":2,"score":0.31529998779296875},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.30720001459121704},{"id":"https://openalex.org/C31601959","wikidata":"https://www.wikidata.org/wiki/Q931309","display_name":"Medical imaging","level":2,"score":0.30070000886917114},{"id":"https://openalex.org/C76297474","wikidata":"https://www.wikidata.org/wiki/Q1898737","display_name":"Morphological analysis","level":2,"score":0.2944999933242798},{"id":"https://openalex.org/C2777522853","wikidata":"https://www.wikidata.org/wiki/Q5276128","display_name":"Digital pathology","level":2,"score":0.28690001368522644},{"id":"https://openalex.org/C112416745","wikidata":"https://www.wikidata.org/wiki/Q974213","display_name":"Digital imaging","level":5,"score":0.28600001335144043},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.26980000734329224},{"id":"https://openalex.org/C544519230","wikidata":"https://www.wikidata.org/wiki/Q32566","display_name":"Computed tomography","level":2,"score":0.2578999996185303},{"id":"https://openalex.org/C3020205268","wikidata":"https://www.wikidata.org/wiki/Q1038886","display_name":"Imaging technique","level":2,"score":0.25209999084472656},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.25029999017715454}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1093/clinchem/hvaf086.144","doi":"https://doi.org/10.1093/clinchem/hvaf086.144","is_oa":true,"landing_page_url":"https://doi.org/10.1093/clinchem/hvaf086.144","pdf_url":"https://academic.oup.com/clinchem/article-pdf/71/Supplement_1/hvaf086.144/64461986/hvaf086.144.pdf","source":{"id":"https://openalex.org/S139212996","display_name":"Clinical Chemistry","issn_l":"0009-9147","issn":["0009-9147","1530-8561"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320272","host_organization_name":"American Association for Clinical Chemistry","host_organization_lineage":["https://openalex.org/P4310320272"],"host_organization_lineage_names":["American Association for Clinical Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Chemistry","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1093/clinchem/hvaf086.144","doi":"https://doi.org/10.1093/clinchem/hvaf086.144","is_oa":true,"landing_page_url":"https://doi.org/10.1093/clinchem/hvaf086.144","pdf_url":"https://academic.oup.com/clinchem/article-pdf/71/Supplement_1/hvaf086.144/64461986/hvaf086.144.pdf","source":{"id":"https://openalex.org/S139212996","display_name":"Clinical Chemistry","issn_l":"0009-9147","issn":["0009-9147","1530-8561"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320272","host_organization_name":"American Association for Clinical Chemistry","host_organization_lineage":["https://openalex.org/P4310320272"],"host_organization_lineage_names":["American Association for Clinical Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.766700029373169,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4414741069.pdf","grobid_xml":"https://content.openalex.org/works/W4414741069.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"Erythrocyte":[2],"morphological":[3,33,63,298],"analysis":[4],"is":[5],"a":[6,70,289,410,414,462],"critical":[7],"diagnostic":[8],"technique":[9],"in":[10,57,353,374,430,457,470],"clinical":[11,458,471],"settings.":[12],"Advanced":[13],"digital":[14,121,129],"morphology":[15,43,123,456],"analyzers":[16],"have":[17,45],"enhanced":[18],"its":[19],"importance":[20],"by":[21],"enabling":[22],"rapid":[23],"imaging":[24],"and":[25,60,114,159,168,188,212,247,249,258,261,279,305,322,369,399,418,442,452],"quantitative":[26],"classification":[27,80,432,469],"of":[28,81,88,127,131,291,377,392,412,416,421,433],"RBCs":[29,83],"based":[30,218],"on":[31,175,219,313,323],"distinct":[32],"characteristics.":[34],"However,":[35],"the":[36,86,118,176,208,268,286,292,314,318,332,348,359,362,375,403,407,431,448],"algorithms":[37],"used":[38],"for":[39,47,78,296,342,351,465],"identifying":[40],"abnormal":[41,82,434,467],"RBC":[42,62,89,99,151,179,183,199,210,320,344,379,468],"still":[44],"room":[46],"improvement.":[48],"Deep":[49],"learning-based":[50],"object":[51,72],"detection":[52,73,303,376],"methods":[53],"offer":[54],"promising":[55],"potential":[56],"more":[58],"accurate":[59],"simplified":[61],"analysis.":[64],"In":[65,193,358,402],"this":[66],"study,":[67],"we":[68,148,195],"introduce":[69],"new":[71],"model":[74,364,408,426,449],"framework,":[75],"YOLO11-RBC,":[76],"designed":[77],"automated":[79,466],"to":[84,347,387],"support":[85],"diagnosis":[87],"related":[90],"diseases.":[91],"Methods":[92],"We":[93,284],"collected":[94],"2106":[95],"blood":[96,132,165,215],"samples":[97,330,336],"with":[98,109,136,300,335,436],"abnormalities":[100,345],"from":[101,162,331,385],"two":[102],"Chinese":[103],"institutions.":[104],"Blood":[105],"smears":[106,133],"were":[107,134,185,264,396],"prepared":[108],"Mindray":[110,119],"SC-120":[111],"slide":[112],"maker":[113],"then":[115],"analyzed":[116],"using":[117],"MC-80":[120],"cell":[122],"analyzer.":[124],"A":[125],"total":[126],"9322":[128],"images":[130,184,211,217],"captured,":[135],"each":[137,201],"image":[138,269],"containing":[139,202],"approximately":[140,203],"100":[141,204],"labeled":[142],"RBCs.":[143,205],"To":[144],"address":[145],"class":[146],"imbalance,":[147],"cropped":[149,177],"rare":[150],"types,":[152],"such":[153],"as":[154,338],"bite":[155,230],"cells,":[156,158,229,231,233,236,240,244,246],"blister":[157,232],"Plasmodium-infected":[160],"RBCs,":[161,435],"6448":[163],"large":[164,191],"smear":[166,216],"images,":[167,200],"performed":[169],"data":[170],"augmentation":[171],"(rotation,":[172],"deformation,":[173],"etc.)":[174],"single":[178],"images.":[180,192],"The":[181,271,308,389,424],"augmented":[182],"randomly":[186,275],"shuffled":[187],"stitched":[189,198,209],"into":[190,277],"total,":[194],"obtained":[196],"520":[197],"Morphologists":[206],"annotated":[207,272],"1586":[213],"original":[214],"three":[220,394],"main":[221],"attributes:":[222],"color":[223],"(hypochromic":[224],"cells),":[225],"shape":[226],"(schistocytes,":[227],"helmet":[228],"irregularly":[234],"contracted":[235],"elliptocytes,":[237],"ovalocytes,":[238],"sickle":[239],"echinocytes,":[241],"stomatocytes,":[242],"target":[243],"teardrop":[245],"acanthocytes),":[248],"inclusions":[250],"(e.g.,":[251],"basophilic":[252],"stippling,":[253],"Pappenheimer":[254],"bodies,":[255,257],"Howell-Jolly":[256],"Plasmodium).":[259],"Agglutination":[260],"rouleaux":[262],"formation":[263],"also":[265],"labelled":[266],"at":[267,317],"level.":[270],"dataset":[273],"was":[274,311],"divided":[276],"training":[278],"test":[280,315,360],"sets":[281],"(7:3":[282],"ratio).":[283],"developed":[285],"YOLO11-RBC":[287,363,425],"model,":[288],"variant":[290],"YOLO":[293],"series,":[294],"optimized":[295],"erythrocyte":[297,455],"recognition":[299],"an":[301,324,419],"improved":[302],"head":[304],"loss":[306],"function.":[307],"model*s":[309],"performance":[310,429],"evaluated":[312],"set":[316,327],"individual":[319],"level":[321],"external":[325,404],"validation":[326,405],"comprising":[328],"1288":[329],"third":[333],"hospital,":[334],"classified":[337],"negative":[339],"or":[340],"positive":[341],"different":[343],"according":[346],"International":[349],"Council":[350],"Standardization":[352],"Haematology":[354],"(ICSH)":[355],"guidelines.":[356],"Results":[357],"set,":[361,406],"demonstrated":[365,427],"high":[366,370,437],"precision":[367],"(89.4%\u201399.0%)":[368],"recall":[371],"rates":[372],"(92.6%\u201399.7%)":[373],"20":[378],"abnormalities,":[380],"which":[381],"F1":[382],"scores":[383],"ranging":[384],"92.0%":[386],"99.3%.":[388],"harmonic":[390],"means":[391],"these":[393],"parameters":[395],"96.4%,":[397],"96.7%,":[398],"96.5%,":[400],"respectively.":[401],"achieved":[409],"sensitivity":[411],"95.0%,":[413],"specificity":[415],"98.9%,":[417],"accuracy":[420],"98.7%.":[422],"Conclusion":[423],"strong":[428],"precision,":[438],"recall,":[439],"sensitivity,":[440],"specificity,":[441],"accuracy.":[443],"These":[444],"results":[445],"indicate":[446],"that":[447],"can":[450],"accurately":[451],"efficiently":[453],"analyze":[454],"samples,":[459],"making":[460],"it":[461],"valuable":[463],"tool":[464],"practice.":[472]},"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2025-10-10T00:00:00"}