{"id":"https://openalex.org/W4414736736","doi":"https://doi.org/10.3390/ijms26199601","title":"Genomic Characterization of a Rare K30-ST198 Hypervirulent Klebsiella pneumoniae Clone with Distinctive Virulence Features","display_name":"Genomic Characterization of a Rare K30-ST198 Hypervirulent Klebsiella pneumoniae Clone with Distinctive Virulence Features","publication_year":2025,"publication_date":"2025-10-01","ids":{"openalex":"https://openalex.org/W4414736736","doi":"https://doi.org/10.3390/ijms26199601","pmid":"https://pubmed.ncbi.nlm.nih.gov/41096865","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12525063"},"language":"en","primary_location":{"id":"doi:10.3390/ijms26199601","doi":"https://doi.org/10.3390/ijms26199601","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms26199601","pdf_url":"https://www.mdpi.com/1422-0067/26/19/9601/pdf?version=1759320045","source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1422-0067/26/19/9601/pdf?version=1759320045","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087904354","display_name":"Domingo Fern\u00e1ndez Vecilla","orcid":"https://orcid.org/0000-0002-4117-0888","observed_orcids":["https://orcid.org/0000-0002-4117-0888"]},"institutions":[{"id":"https://openalex.org/I4210099858","display_name":"Marqu\u00e9s de Valdecilla University Hospital","ror":"https://ror.org/01w4yqf75","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210099858"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Domingo Fern\u00e1ndez Vecilla","raw_affiliation_strings":["Microbiology Service, University Hospital Marqu\u00e9s de Valdecilla, Av. Valdecilla s/n, 39008 Santander, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiology Service, University Hospital Marqu\u00e9s de Valdecilla, Av. Valdecilla s/n, 39008 Santander, Spain","institution_ids":["https://openalex.org/I4210099858"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081808336","display_name":"Jorge Rodr\u00edguez-Grande","orcid":"https://orcid.org/0000-0002-8229-6049","observed_orcids":["https://orcid.org/0000-0002-8229-6049"]},"institutions":[{"id":"https://openalex.org/I2801357902","display_name":"Instituto de Salud Carlos III","ror":"https://ror.org/00ca2c886","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4387152914"]},{"id":"https://openalex.org/I4210113075","display_name":"Instituto de Investigaci\u00f3n Marqu\u00e9s de Valdecilla","ror":"https://ror.org/025gxrt12","country_code":"ES","type":"other","lineage":["https://openalex.org/I13134134","https://openalex.org/I4210113075"]},{"id":"https://openalex.org/I4405268343","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red Enfermedades Infecciosas","ror":"https://ror.org/00nd8zg79","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4405268343"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Jorge Rodr\u00edguez Grande","raw_affiliation_strings":["CIBERINFEC, Health Institute Carlos III, Monforte de Lemos, 5, 28020 Madrid, Spain","Marqu\u00e9s de Valdecilla Research Institute (IDIVAL), Av. Valdecilla s/n, 39008 Santander, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBERINFEC, Health Institute Carlos III, Monforte de Lemos, 5, 28020 Madrid, Spain","institution_ids":["https://openalex.org/I2801357902","https://openalex.org/I4405268343"]},{"raw_affiliation_string":"Marqu\u00e9s de Valdecilla Research Institute (IDIVAL), Av. Valdecilla s/n, 39008 Santander, Spain","institution_ids":["https://openalex.org/I4210113075"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093329392","display_name":"Nuria Fraile Valc\u00e1rcel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210113075","display_name":"Instituto de Investigaci\u00f3n Marqu\u00e9s de Valdecilla","ror":"https://ror.org/025gxrt12","country_code":"ES","type":"other","lineage":["https://openalex.org/I13134134","https://openalex.org/I4210113075"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Nuria Fraile Valc\u00e1rcel","raw_affiliation_strings":["Marqu\u00e9s de Valdecilla Research Institute (IDIVAL), Av. Valdecilla s/n, 39008 Santander, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Marqu\u00e9s de Valdecilla Research Institute (IDIVAL), Av. Valdecilla s/n, 39008 Santander, Spain","institution_ids":["https://openalex.org/I4210113075"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081253130","display_name":"Mary Paz Roche Matheus","orcid":"https://orcid.org/0000-0002-5819-0148","observed_orcids":["https://orcid.org/0000-0002-5819-0148"]},"institutions":[{"id":"https://openalex.org/I4210092871","display_name":"Hospital de Basurto","ror":"https://ror.org/00j4pze04","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210092871","https://openalex.org/I4210125364"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Mary Paz Roche Matheus","raw_affiliation_strings":["Basurto University Hospital, Montevideo Etorb., 18, Basurtu-Zorrotza, 48013 Bilbao, Spain"],"raw_orcid":"https://orcid.org/0000-0002-5819-0148","affiliations":[{"raw_affiliation_string":"Basurto University Hospital, Montevideo Etorb., 18, Basurtu-Zorrotza, 48013 Bilbao, Spain","institution_ids":["https://openalex.org/I4210092871"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036605944","display_name":"Gotzon Iglesias Hidalgo","orcid":"https://orcid.org/0000-0001-5818-084X","observed_orcids":["https://orcid.org/0000-0001-5818-084X"]},"institutions":[{"id":"https://openalex.org/I4210137412","display_name":"Hospital de Cruces","ror":"https://ror.org/03nzegx43","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210125364","https://openalex.org/I4210137412"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Gotzon Iglesias Hidalgo","raw_affiliation_strings":["Cruces University Hospital, Cruces Plaza, 12, 48903 Barakaldo, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cruces University Hospital, Cruces Plaza, 12, 48903 Barakaldo, Spain","institution_ids":["https://openalex.org/I4210137412"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001552849","display_name":"Cristina Aspichueta Vivanco","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210089430","display_name":"BioCruces Health research Institute","ror":"https://ror.org/0061s4v88","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I4210089430"]},{"id":"https://openalex.org/I4210092871","display_name":"Hospital de Basurto","ror":"https://ror.org/00j4pze04","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210092871","https://openalex.org/I4210125364"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Cristina Aspichueta Vivanco","raw_affiliation_strings":["Basurto University Hospital, Montevideo Etorb., 18, Basurtu-Zorrotza, 48013 Bilbao, Spain","Bioruces Health Research Institute, Cruces Plaza, 48903 Barakaldo, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Basurto University Hospital, Montevideo Etorb., 18, Basurtu-Zorrotza, 48013 Bilbao, Spain","institution_ids":["https://openalex.org/I4210092871"]},{"raw_affiliation_string":"Bioruces Health Research Institute, Cruces Plaza, 48903 Barakaldo, Spain","institution_ids":["https://openalex.org/I4210089430"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047384954","display_name":"Jos\u00e9 Luis D\u00edaz de Tuesta del Arco","orcid":"https://orcid.org/0000-0002-0095-7430","observed_orcids":["https://orcid.org/0000-0002-0095-7430"]},"institutions":[{"id":"https://openalex.org/I4210089430","display_name":"BioCruces Health research Institute","ror":"https://ror.org/0061s4v88","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I4210089430"]},{"id":"https://openalex.org/I4210092871","display_name":"Hospital de Basurto","ror":"https://ror.org/00j4pze04","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210092871","https://openalex.org/I4210125364"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Jos\u00e9 Luis D\u00edaz de Tuesta del Arco","raw_affiliation_strings":["Basurto University Hospital, Montevideo Etorb., 18, Basurtu-Zorrotza, 48013 Bilbao, Spain","Bioruces Health Research Institute, Cruces Plaza, 48903 Barakaldo, Spain"],"raw_orcid":"https://orcid.org/0000-0002-0095-7430","affiliations":[{"raw_affiliation_string":"Basurto University Hospital, Montevideo Etorb., 18, Basurtu-Zorrotza, 48013 Bilbao, Spain","institution_ids":["https://openalex.org/I4210092871"]},{"raw_affiliation_string":"Bioruces Health Research Institute, Cruces Plaza, 48903 Barakaldo, Spain","institution_ids":["https://openalex.org/I4210089430"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001937225","display_name":"Sergio Garc\u00eda Fern\u00e1ndez","orcid":"https://orcid.org/0000-0003-3282-2132","observed_orcids":["https://orcid.org/0000-0003-3282-2132"]},"institutions":[{"id":"https://openalex.org/I2801357902","display_name":"Instituto de Salud Carlos III","ror":"https://ror.org/00ca2c886","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4387152914"]},{"id":"https://openalex.org/I4210099858","display_name":"Marqu\u00e9s de Valdecilla University Hospital","ror":"https://ror.org/01w4yqf75","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210099858"]},{"id":"https://openalex.org/I4210113075","display_name":"Instituto de Investigaci\u00f3n Marqu\u00e9s de Valdecilla","ror":"https://ror.org/025gxrt12","country_code":"ES","type":"other","lineage":["https://openalex.org/I13134134","https://openalex.org/I4210113075"]},{"id":"https://openalex.org/I4405268343","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red Enfermedades Infecciosas","ror":"https://ror.org/00nd8zg79","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4405268343"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Sergio Garc\u00eda-Fern\u00e1ndez","raw_affiliation_strings":["CIBERINFEC, Health Institute Carlos III, Monforte de Lemos, 5, 28020 Madrid, Spain","Marqu\u00e9s de Valdecilla Research Institute (IDIVAL), Av. Valdecilla s/n, 39008 Santander, Spain","Microbiology Service, University Hospital Marqu\u00e9s de Valdecilla, Av. Valdecilla s/n, 39008 Santander, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBERINFEC, Health Institute Carlos III, Monforte de Lemos, 5, 28020 Madrid, Spain","institution_ids":["https://openalex.org/I2801357902","https://openalex.org/I4405268343"]},{"raw_affiliation_string":"Marqu\u00e9s de Valdecilla Research Institute (IDIVAL), Av. Valdecilla s/n, 39008 Santander, Spain","institution_ids":["https://openalex.org/I4210113075"]},{"raw_affiliation_string":"Microbiology Service, University Hospital Marqu\u00e9s de Valdecilla, Av. Valdecilla s/n, 39008 Santander, Spain","institution_ids":["https://openalex.org/I4210099858"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114127434","display_name":"Mar\u00eda Siller Ruiz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210099858","display_name":"Marqu\u00e9s de Valdecilla University Hospital","ror":"https://ror.org/01w4yqf75","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210099858"]},{"id":"https://openalex.org/I4210113075","display_name":"Instituto de Investigaci\u00f3n Marqu\u00e9s de Valdecilla","ror":"https://ror.org/025gxrt12","country_code":"ES","type":"other","lineage":["https://openalex.org/I13134134","https://openalex.org/I4210113075"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Mar\u00eda Siller Ruiz","raw_affiliation_strings":["Marqu\u00e9s de Valdecilla Research Institute (IDIVAL), Av. Valdecilla s/n, 39008 Santander, Spain","Microbiology Service, University Hospital Marqu\u00e9s de Valdecilla, Av. Valdecilla s/n, 39008 Santander, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Marqu\u00e9s de Valdecilla Research Institute (IDIVAL), Av. Valdecilla s/n, 39008 Santander, Spain","institution_ids":["https://openalex.org/I4210113075"]},{"raw_affiliation_string":"Microbiology Service, University Hospital Marqu\u00e9s de Valdecilla, Av. Valdecilla s/n, 39008 Santander, Spain","institution_ids":["https://openalex.org/I4210099858"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027794092","display_name":"Zaira Moure","orcid":"https://orcid.org/0000-0002-3613-6386","observed_orcids":["https://orcid.org/0000-0002-3613-6386"]},"institutions":[{"id":"https://openalex.org/I2801357902","display_name":"Instituto de Salud Carlos III","ror":"https://ror.org/00ca2c886","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4387152914"]},{"id":"https://openalex.org/I4210099858","display_name":"Marqu\u00e9s de Valdecilla University Hospital","ror":"https://ror.org/01w4yqf75","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210099858"]},{"id":"https://openalex.org/I4210113075","display_name":"Instituto de Investigaci\u00f3n Marqu\u00e9s de Valdecilla","ror":"https://ror.org/025gxrt12","country_code":"ES","type":"other","lineage":["https://openalex.org/I13134134","https://openalex.org/I4210113075"]},{"id":"https://openalex.org/I4405268343","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red Enfermedades Infecciosas","ror":"https://ror.org/00nd8zg79","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4405268343"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Zaira Moure","raw_affiliation_strings":["CIBERINFEC, Health Institute Carlos III, Monforte de Lemos, 5, 28020 Madrid, Spain","Marqu\u00e9s de Valdecilla Research Institute (IDIVAL), Av. Valdecilla s/n, 39008 Santander, Spain","Microbiology Service, University Hospital Marqu\u00e9s de Valdecilla, Av. Valdecilla s/n, 39008 Santander, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBERINFEC, Health Institute Carlos III, Monforte de Lemos, 5, 28020 Madrid, Spain","institution_ids":["https://openalex.org/I2801357902","https://openalex.org/I4405268343"]},{"raw_affiliation_string":"Marqu\u00e9s de Valdecilla Research Institute (IDIVAL), Av. Valdecilla s/n, 39008 Santander, Spain","institution_ids":["https://openalex.org/I4210113075"]},{"raw_affiliation_string":"Microbiology Service, University Hospital Marqu\u00e9s de Valdecilla, Av. Valdecilla s/n, 39008 Santander, Spain","institution_ids":["https://openalex.org/I4210099858"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5119807322","display_name":"Daniela Vallejo Iriarte","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210113075","display_name":"Instituto de Investigaci\u00f3n Marqu\u00e9s de Valdecilla","ror":"https://ror.org/025gxrt12","country_code":"ES","type":"other","lineage":["https://openalex.org/I13134134","https://openalex.org/I4210113075"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Daniela Vallejo Iriarte","raw_affiliation_strings":["Marqu\u00e9s de Valdecilla Research Institute (IDIVAL), Av. Valdecilla s/n, 39008 Santander, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Marqu\u00e9s de Valdecilla Research Institute (IDIVAL), Av. Valdecilla s/n, 39008 Santander, Spain","institution_ids":["https://openalex.org/I4210113075"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079594462","display_name":"Athanasia Varsaki","orcid":"https://orcid.org/0000-0001-6739-8859","observed_orcids":["https://orcid.org/0000-0001-6739-8859"]},"institutions":[{"id":"https://openalex.org/I4405258579","display_name":"Centro de Investigaci\u00f3n y Formaci\u00f3n Agrarias","ror":"https://ror.org/00xt72h88","country_code":"ES","type":"government","lineage":["https://openalex.org/I4405258579"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Athanasia Varsaki","raw_affiliation_strings":["Centro de Investigaci\u00f3n y Formaci\u00f3n Agrarias (CIFA), 39600 Muriedas, Spain"],"raw_orcid":"https://orcid.org/0000-0001-6739-8859","affiliations":[{"raw_affiliation_string":"Centro de Investigaci\u00f3n y Formaci\u00f3n Agrarias (CIFA), 39600 Muriedas, Spain","institution_ids":["https://openalex.org/I4405258579"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102852770","display_name":"Jorge Calvo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801357902","display_name":"Instituto de Salud Carlos III","ror":"https://ror.org/00ca2c886","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4387152914"]},{"id":"https://openalex.org/I4210099858","display_name":"Marqu\u00e9s de Valdecilla University Hospital","ror":"https://ror.org/01w4yqf75","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210099858"]},{"id":"https://openalex.org/I4210113075","display_name":"Instituto de Investigaci\u00f3n Marqu\u00e9s de Valdecilla","ror":"https://ror.org/025gxrt12","country_code":"ES","type":"other","lineage":["https://openalex.org/I13134134","https://openalex.org/I4210113075"]},{"id":"https://openalex.org/I4405268343","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red Enfermedades Infecciosas","ror":"https://ror.org/00nd8zg79","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4405268343"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Jorge Calvo Montes","raw_affiliation_strings":["CIBERINFEC, Health Institute Carlos III, Monforte de Lemos, 5, 28020 Madrid, Spain","Marqu\u00e9s de Valdecilla Research Institute (IDIVAL), Av. Valdecilla s/n, 39008 Santander, Spain","Microbiology Service, University Hospital Marqu\u00e9s de Valdecilla, Av. Valdecilla s/n, 39008 Santander, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBERINFEC, Health Institute Carlos III, Monforte de Lemos, 5, 28020 Madrid, Spain","institution_ids":["https://openalex.org/I2801357902","https://openalex.org/I4405268343"]},{"raw_affiliation_string":"Marqu\u00e9s de Valdecilla Research Institute (IDIVAL), Av. Valdecilla s/n, 39008 Santander, Spain","institution_ids":["https://openalex.org/I4210113075"]},{"raw_affiliation_string":"Microbiology Service, University Hospital Marqu\u00e9s de Valdecilla, Av. Valdecilla s/n, 39008 Santander, Spain","institution_ids":["https://openalex.org/I4210099858"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027010651","display_name":"Mar\u00eda P\u00eda Roiz Mesones","orcid":"https://orcid.org/0000-0001-8677-8128","observed_orcids":["https://orcid.org/0000-0001-8677-8128"]},"institutions":[{"id":"https://openalex.org/I2801357902","display_name":"Instituto de Salud Carlos III","ror":"https://ror.org/00ca2c886","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4387152914"]},{"id":"https://openalex.org/I4210099858","display_name":"Marqu\u00e9s de Valdecilla University Hospital","ror":"https://ror.org/01w4yqf75","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210099858"]},{"id":"https://openalex.org/I4210113075","display_name":"Instituto de Investigaci\u00f3n Marqu\u00e9s de Valdecilla","ror":"https://ror.org/025gxrt12","country_code":"ES","type":"other","lineage":["https://openalex.org/I13134134","https://openalex.org/I4210113075"]},{"id":"https://openalex.org/I4405268343","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red Enfermedades Infecciosas","ror":"https://ror.org/00nd8zg79","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4405268343"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Mar\u00eda P\u00eda Roiz Mesones","raw_affiliation_strings":["CIBERINFEC, Health Institute Carlos III, Monforte de Lemos, 5, 28020 Madrid, Spain","Marqu\u00e9s de Valdecilla Research Institute (IDIVAL), Av. Valdecilla s/n, 39008 Santander, Spain","Microbiology Service, University Hospital Marqu\u00e9s de Valdecilla, Av. Valdecilla s/n, 39008 Santander, Spain"],"raw_orcid":"https://orcid.org/0000-0001-8677-8128","affiliations":[{"raw_affiliation_string":"CIBERINFEC, Health Institute Carlos III, Monforte de Lemos, 5, 28020 Madrid, Spain","institution_ids":["https://openalex.org/I2801357902","https://openalex.org/I4405268343"]},{"raw_affiliation_string":"Marqu\u00e9s de Valdecilla Research Institute (IDIVAL), Av. Valdecilla s/n, 39008 Santander, Spain","institution_ids":["https://openalex.org/I4210113075"]},{"raw_affiliation_string":"Microbiology Service, University Hospital Marqu\u00e9s de Valdecilla, Av. Valdecilla s/n, 39008 Santander, Spain","institution_ids":["https://openalex.org/I4210099858"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109063905","display_name":"Mar\u00eda Carmen Fari\u00f1as","orcid":"https://orcid.org/0000-0002-9259-2730","observed_orcids":["https://orcid.org/0000-0002-9259-2730"]},"institutions":[{"id":"https://openalex.org/I2801357902","display_name":"Instituto de Salud Carlos III","ror":"https://ror.org/00ca2c886","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4387152914"]},{"id":"https://openalex.org/I4210099858","display_name":"Marqu\u00e9s de Valdecilla University Hospital","ror":"https://ror.org/01w4yqf75","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210099858"]},{"id":"https://openalex.org/I4210113075","display_name":"Instituto de Investigaci\u00f3n Marqu\u00e9s de Valdecilla","ror":"https://ror.org/025gxrt12","country_code":"ES","type":"other","lineage":["https://openalex.org/I13134134","https://openalex.org/I4210113075"]},{"id":"https://openalex.org/I4405268343","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red Enfermedades Infecciosas","ror":"https://ror.org/00nd8zg79","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4405268343"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Mar\u00eda Carmen Fari\u00f1as","raw_affiliation_strings":["CIBERINFEC, Health Institute Carlos III, Monforte de Lemos, 5, 28020 Madrid, Spain","Infectious Diseases Service, University Hospital Marqu\u00e9s de Valdecilla, Av. Valdecilla s/n, 39008 Santander, Spain","Marqu\u00e9s de Valdecilla Research Institute (IDIVAL), Av. Valdecilla s/n, 39008 Santander, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBERINFEC, Health Institute Carlos III, Monforte de Lemos, 5, 28020 Madrid, Spain","institution_ids":["https://openalex.org/I2801357902","https://openalex.org/I4405268343"]},{"raw_affiliation_string":"Infectious Diseases Service, University Hospital Marqu\u00e9s de Valdecilla, Av. Valdecilla s/n, 39008 Santander, Spain","institution_ids":["https://openalex.org/I4210099858"]},{"raw_affiliation_string":"Marqu\u00e9s de Valdecilla Research Institute (IDIVAL), Av. Valdecilla s/n, 39008 Santander, Spain","institution_ids":["https://openalex.org/I4210113075"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034274177","display_name":"Alain A. Ocampo-Sosa","orcid":"https://orcid.org/0000-0002-9104-3115","observed_orcids":["https://orcid.org/0000-0002-9104-3115"]},"institutions":[{"id":"https://openalex.org/I2801357902","display_name":"Instituto de Salud Carlos III","ror":"https://ror.org/00ca2c886","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4387152914"]},{"id":"https://openalex.org/I4210099858","display_name":"Marqu\u00e9s de Valdecilla University Hospital","ror":"https://ror.org/01w4yqf75","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210099858"]},{"id":"https://openalex.org/I4210113075","display_name":"Instituto de Investigaci\u00f3n Marqu\u00e9s de Valdecilla","ror":"https://ror.org/025gxrt12","country_code":"ES","type":"other","lineage":["https://openalex.org/I13134134","https://openalex.org/I4210113075"]},{"id":"https://openalex.org/I4405268343","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red Enfermedades Infecciosas","ror":"https://ror.org/00nd8zg79","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4405268343"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Alain A. Ocampo-Sosa","raw_affiliation_strings":["CIBERINFEC, Health Institute Carlos III, Monforte de Lemos, 5, 28020 Madrid, Spain","Marqu\u00e9s de Valdecilla Research Institute (IDIVAL), Av. Valdecilla s/n, 39008 Santander, Spain","Microbiology Service, University Hospital Marqu\u00e9s de Valdecilla, Av. Valdecilla s/n, 39008 Santander, Spain"],"raw_orcid":"https://orcid.org/0000-0002-9104-3115","affiliations":[{"raw_affiliation_string":"CIBERINFEC, Health Institute Carlos III, Monforte de Lemos, 5, 28020 Madrid, Spain","institution_ids":["https://openalex.org/I2801357902","https://openalex.org/I4405268343"]},{"raw_affiliation_string":"Marqu\u00e9s de Valdecilla Research Institute (IDIVAL), Av. Valdecilla s/n, 39008 Santander, Spain","institution_ids":["https://openalex.org/I4210113075"]},{"raw_affiliation_string":"Microbiology Service, University Hospital Marqu\u00e9s de Valdecilla, Av. Valdecilla s/n, 39008 Santander, Spain","institution_ids":["https://openalex.org/I4210099858"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5034274177","https://openalex.org/A5087904354"],"corresponding_institution_ids":["https://openalex.org/I2801357902","https://openalex.org/I4210099858","https://openalex.org/I4210113075","https://openalex.org/I4405268343"],"apc_list":{"value":2900,"currency":"CHF","value_usd":3499},"apc_paid":{"value":2900,"currency":"CHF","value_usd":3499},"fwci":0.2787,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.49075943,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"26","issue":"19","first_page":"9601","last_page":"9601"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.8237000107765198,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.8237000107765198,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13849","display_name":"Enterobacteriaceae and Cronobacter Research","score":0.1005999967455864,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10943","display_name":"Escherichia coli research studies","score":0.04340000078082085,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypervirulent-klebsiella-pneumoniae","display_name":"hypervirulent Klebsiella pneumoniae","score":0.9940000176429749},{"id":"https://openalex.org/keywords/rmpa","display_name":"rmpA","score":0.9610000252723694},{"id":"https://openalex.org/keywords/biofilm-formation","display_name":"biofilm formation","score":0.6399999856948853},{"id":"https://openalex.org/keywords/liver-abscess","display_name":"liver abscess","score":0.8149999976158142},{"id":"https://openalex.org/keywords/urinary-tract-infection","display_name":"urinary tract infection","score":0.8450000286102295},{"id":"https://openalex.org/keywords/virulence-factors","display_name":"virulence factors","score":0.5920000076293945},{"id":"https://openalex.org/keywords/galleria-mellonella-infection-model","display_name":"Galleria mellonella infection model","score":0.7889999747276306},{"id":"https://openalex.org/keywords/ampicillin-resistance","display_name":"ampicillin resistance","score":0.6269999742507935}],"concepts":[{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.9466000199317932},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8226000070571899},{"id":"https://openalex.org/C2777058267","wikidata":"https://www.wikidata.org/wiki/Q132592","display_name":"Klebsiella pneumoniae","level":4,"score":0.7239999771118164},{"id":"https://openalex.org/C2776021129","wikidata":"https://www.wikidata.org/wiki/Q244150","display_name":"Ampicillin","level":3,"score":0.6991000175476074},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.675599992275238},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.6412000060081482},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.5958999991416931},{"id":"https://openalex.org/C94665300","wikidata":"https://www.wikidata.org/wiki/Q63391344","display_name":"Antibiotic resistance","level":3,"score":0.5504000186920166},{"id":"https://openalex.org/C81089528","wikidata":"https://www.wikidata.org/wiki/Q5134986","display_name":"clone (Java method)","level":3,"score":0.5461999773979187},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.444599986076355},{"id":"https://openalex.org/C2778022156","wikidata":"https://www.wikidata.org/wiki/Q576145","display_name":"Strain (injury)","level":2,"score":0.42829999327659607},{"id":"https://openalex.org/C77434933","wikidata":"https://www.wikidata.org/wiki/Q4043440","display_name":"Multilocus sequence typing","level":4,"score":0.3668000102043152},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.3625999987125397},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.36059999465942383},{"id":"https://openalex.org/C58123911","wikidata":"https://www.wikidata.org/wiki/Q467410","display_name":"Biofilm","level":3,"score":0.3495999872684479},{"id":"https://openalex.org/C180223184","wikidata":"https://www.wikidata.org/wiki/Q4839986","display_name":"Bacterial genetics","level":4,"score":0.33660000562667847},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.32260000705718994},{"id":"https://openalex.org/C24432333","wikidata":"https://www.wikidata.org/wiki/Q2068526","display_name":"Whole genome sequencing","level":4,"score":0.3215999901294708},{"id":"https://openalex.org/C2779116282","wikidata":"https://www.wikidata.org/wiki/Q131854","display_name":"Klebsiella","level":4,"score":0.30300000309944153},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.3012999892234802},{"id":"https://openalex.org/C133936738","wikidata":"https://www.wikidata.org/wiki/Q643839","display_name":"Multiple drug resistance","level":3,"score":0.28049999475479126},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.28049999475479126},{"id":"https://openalex.org/C114851261","wikidata":"https://www.wikidata.org/wiki/Q12147416","display_name":"Drug resistance","level":2,"score":0.2590000033378601},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.2547000050544739},{"id":"https://openalex.org/C2781090273","wikidata":"https://www.wikidata.org/wiki/Q1623405","display_name":"Virulence factor","level":4,"score":0.25220000743865967}],"mesh":[{"descriptor_ui":"D000073336","descriptor_name":"Whole Genome Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007710","descriptor_name":"Klebsiella Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D007711","descriptor_name":"Klebsiella pneumoniae","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D007711","descriptor_name":"Klebsiella pneumoniae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D007711","descriptor_name":"Klebsiella pneumoniae","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D007711","descriptor_name":"Klebsiella pneumoniae","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":true},{"descriptor_ui":"D008100","descriptor_name":"Liver Abscess","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014552","descriptor_name":"Urinary Tract Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D014774","descriptor_name":"Virulence","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016680","descriptor_name":"Genome, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018441","descriptor_name":"Biofilms","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D037521","descriptor_name":"Virulence Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.3390/ijms26199601","doi":"https://doi.org/10.3390/ijms26199601","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms26199601","pdf_url":"https://www.mdpi.com/1422-0067/26/19/9601/pdf?version=1759320045","source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:11336708","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12525063","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:41096865","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41096865","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of molecular sciences","raw_type":"Journal Article"},{"id":"pmh:oai:repositorio.unican.es:10902/38617","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/10902/38617","pdf_url":"https://repositorio.unican.es/xmlui/bitstream/10902/38617/3/GenomicCharacterizationRareK30ST198.pdf","source":{"id":"https://openalex.org/S4306400398","display_name":"UCrea (University of Cantabria)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I13134134","host_organization_name":"Universidad de Cantabria","host_organization_lineage":["https://openalex.org/I13134134"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Molecular Sciences, 2025, 26(19), 9601","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.3390/ijms26199601","doi":"https://doi.org/10.3390/ijms26199601","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ijms26199601","pdf_url":"https://www.mdpi.com/1422-0067/26/19/9601/pdf?version=1759320045","source":{"id":"https://openalex.org/S10623703","display_name":"International Journal of Molecular Sciences","issn_l":"1422-0067","issn":["1422-0067","1661-6596"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","medline","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Molecular Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G7425069594","display_name":null,"funder_award_id":"NVAL24/10","funder_id":"https://openalex.org/F4320330035","funder_display_name":"Instituto de Investigaci\u00f3n Marqu\u00e9s de Valdecilla"}],"funders":[{"id":"https://openalex.org/F4320330035","display_name":"Instituto de Investigaci\u00f3n Marqu\u00e9s de Valdecilla","ror":"https://ror.org/025gxrt12"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4414736736.pdf","grobid_xml":"https://content.openalex.org/works/W4414736736.grobid-xml"},"referenced_works_count":58,"referenced_works":["https://openalex.org/W1895017250","https://openalex.org/W1951178169","https://openalex.org/W1965273688","https://openalex.org/W1971386101","https://openalex.org/W1991331030","https://openalex.org/W2051257969","https://openalex.org/W2059372590","https://openalex.org/W2063125558","https://openalex.org/W2105048518","https://openalex.org/W2114853012","https://openalex.org/W2124970172","https://openalex.org/W2134852597","https://openalex.org/W2141160466","https://openalex.org/W2143325926","https://openalex.org/W2145855467","https://openalex.org/W2152709373","https://openalex.org/W2163468401","https://openalex.org/W2231991559","https://openalex.org/W2395318188","https://openalex.org/W2443415468","https://openalex.org/W2475160309","https://openalex.org/W2558482643","https://openalex.org/W2735364652","https://openalex.org/W2770546211","https://openalex.org/W2783961388","https://openalex.org/W2789814710","https://openalex.org/W2793582850","https://openalex.org/W2808824345","https://openalex.org/W2903680162","https://openalex.org/W2945505394","https://openalex.org/W2972779137","https://openalex.org/W2982466468","https://openalex.org/W2987013299","https://openalex.org/W2999566645","https://openalex.org/W3016890450","https://openalex.org/W3032900735","https://openalex.org/W3088023342","https://openalex.org/W3110742410","https://openalex.org/W3136455567","https://openalex.org/W3140308228","https://openalex.org/W3159970040","https://openalex.org/W3177828909","https://openalex.org/W3181261361","https://openalex.org/W3209528471","https://openalex.org/W4205374232","https://openalex.org/W4281790889","https://openalex.org/W4291926378","https://openalex.org/W4313585994","https://openalex.org/W4378472957","https://openalex.org/W4386569540","https://openalex.org/W4386910870","https://openalex.org/W4388630770","https://openalex.org/W4389145214","https://openalex.org/W4390941413","https://openalex.org/W4405438551","https://openalex.org/W4408071230","https://openalex.org/W4411604135","https://openalex.org/W4413409374"],"related_works":["https://openalex.org/W7110592615","https://openalex.org/W3035798180","https://openalex.org/W3118651384","https://openalex.org/W2231991559","https://openalex.org/W4213339552","https://openalex.org/W7144173728","https://openalex.org/W4412776366","https://openalex.org/W4411450772","https://openalex.org/W4408611947","https://openalex.org/W4391650408"],"abstract_inverted_index":{"Hypervirulent":[0],"Klebsiella":[1],"pneumoniae":[2],"(hvKp)":[3],"has":[4],"emerged":[5],"as":[6],"a":[7,21,52,59,83],"significant":[8],"public":[9],"health":[10],"concern,":[11],"yet":[12],"rare":[13],"sublineages":[14],"remain":[15],"poorly":[16],"characterized.":[17],"Here,":[18],"we":[19],"described":[20],"K30-ST198":[22,184],"hvKp":[23,73,197],"sublineage":[24],"identified":[25,118],"in":[26,79,92,96,100,196],"four":[27],"isolates":[28,57],"from":[29,43,51],"two":[30],"patients,":[31],"including":[32],"three":[33],"sequential":[34],"strains":[35],"(K30B1,":[36],"K30B2,":[37,94],"K30B3)":[38],"recovered":[39],"over":[40],"eight":[41],"months":[42],"recurrent":[44],"liver":[45],"abscesses":[46],"and":[47,62,67,77,148,152,161,193],"one":[48,177],"strain":[49],"(K30-HUMV1)":[50],"urinary":[53],"tract":[54],"infection.":[55],"All":[56],"exhibited":[58],"yYpermucoviscous":[60],"phenotype":[61],"resistance":[63,142],"restricted":[64],"to":[65,146],"ampicillin":[66],"amoxicillin.":[68],"Screening":[69],"with":[70,129],"the":[71,103,113,119,179,187],"eazyplex":[72],"assay":[74],"detected":[75],"ybt":[76],"rmpA":[78],"all":[80],"strains,":[81],"yielding":[82],"virulence":[84,111,131],"score":[85],"of":[86,178,183],"1.":[87],"Biofilm":[88],"production":[89],"was":[90],"strong":[91],"K30B1,":[93],"moderate":[95],"K30-HUMV1,":[97],"but":[98],"weak":[99],"K30B3.":[101],"In":[102],"Galleria":[104],"mellonella":[105],"infection":[106],"model,":[107],"K30B1":[108],"showed":[109],"higher":[110],"than":[112],"other":[114],"isolates.":[115],"Whole-genome":[116],"sequencing":[117],"ICEKp1":[120],"carrying":[121],"hypervirulence-associated":[122],"genes":[123,143],"(ybt,":[124],"pagO,":[125],"rmpAC,":[126],"iroBCDN)":[127],"together":[128],"additional":[130],"factors":[132],"(fim,":[133],"mrkD,":[134],"uge,":[135],"ureA,":[136],"wabG,":[137],"wcaJ,":[138],"mliC),":[139],"while":[140],"antibiotic":[141],"were":[144,156],"limited":[145],"fosA":[147],"blaSHV-77.":[149],"Protein":[150],"structures":[151],"their":[153],"functional":[154],"domains":[155],"predicted":[157],"using":[158],"AlphaFold":[159],"v3.0.1":[160],"ColabFold":[162],"v1.5.5,":[163],"based":[164],"on":[165],"pLDDT":[166],"scores,":[167],"providing":[168],"further":[169],"insights":[170],"into":[171],"gene":[172],"functionality.":[173],"This":[174],"work":[175],"represents":[176],"first":[180],"detailed":[181],"characterizations":[182],"hvKp,":[185],"underscoring":[186],"need":[188],"for":[189],"integrated":[190],"genomic,":[191],"phenotypic,":[192],"structural":[194],"approaches":[195],"surveillance.":[198]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2025-10-02T00:00:00"}