{"id":"https://openalex.org/W4414724947","doi":"https://doi.org/10.1021/acs.jafc.5c06978","title":"Design, Synthesis, and Bioactivity Study of \u03b1-Thiocyanato-Substituted Spirocyclic Tetramic Acid Derivatives","display_name":"Design, Synthesis, and Bioactivity Study of \u03b1-Thiocyanato-Substituted Spirocyclic Tetramic Acid Derivatives","publication_year":2025,"publication_date":"2025-10-01","ids":{"openalex":"https://openalex.org/W4414724947","doi":"https://doi.org/10.1021/acs.jafc.5c06978","pmid":"https://pubmed.ncbi.nlm.nih.gov/41032356"},"language":"en","primary_location":{"id":"doi:10.1021/acs.jafc.5c06978","doi":"https://doi.org/10.1021/acs.jafc.5c06978","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.jafc.5c06978","pdf_url":null,"source":{"id":"https://openalex.org/S134644764","display_name":"Journal of Agricultural and Food Chemistry","issn_l":"0021-8561","issn":["0021-8561","1520-5118"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Agricultural and Food Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053409717","display_name":"Yuxuan Zhao","orcid":"https://orcid.org/0009-0004-4446-6539","observed_orcids":["https://orcid.org/0009-0004-4446-6539"]},"institutions":[{"id":"https://openalex.org/I143593769","display_name":"East China University of Science and Technology","ror":"https://ror.org/01vyrm377","country_code":"CN","type":"education","lineage":["https://openalex.org/I143593769"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuxuan Zhao","raw_affiliation_strings":["Shanghai Key Laboratory of Chemical Biology & School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Key Laboratory of Chemical Biology & School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P. R. China","institution_ids":["https://openalex.org/I143593769"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017093588","display_name":"Xiaoqin Zeng","orcid":"https://orcid.org/0000-0002-1466-070X","observed_orcids":["https://orcid.org/0000-0002-1466-070X"]},"institutions":[{"id":"https://openalex.org/I143593769","display_name":"East China University of Science and Technology","ror":"https://ror.org/01vyrm377","country_code":"CN","type":"education","lineage":["https://openalex.org/I143593769"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoqin Zeng","raw_affiliation_strings":["Shanghai Key Laboratory of Chemical Biology & School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Key Laboratory of Chemical Biology & School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P. R. China","institution_ids":["https://openalex.org/I143593769"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102440697","display_name":"Juncheng Xiang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Juncheng Xiang","raw_affiliation_strings":["Shanghai GreenTech Laboratory Co., Ltd"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai GreenTech Laboratory Co., Ltd","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100350465","display_name":"Yang Chen","orcid":"https://orcid.org/0000-0002-9838-0843","observed_orcids":["https://orcid.org/0000-0002-9838-0843"]},"institutions":[{"id":"https://openalex.org/I143593769","display_name":"East China University of Science and Technology","ror":"https://ror.org/01vyrm377","country_code":"CN","type":"education","lineage":["https://openalex.org/I143593769"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yang Chen","raw_affiliation_strings":["Shanghai Key Laboratory of Chemical Biology & School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Key Laboratory of Chemical Biology & School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P. R. China","institution_ids":["https://openalex.org/I143593769"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100354708","display_name":"Yang Zhang","orcid":"https://orcid.org/0000-0002-6804-1840","observed_orcids":["https://orcid.org/0000-0002-6804-1840"]},"institutions":[{"id":"https://openalex.org/I143593769","display_name":"East China University of Science and Technology","ror":"https://ror.org/01vyrm377","country_code":"CN","type":"education","lineage":["https://openalex.org/I143593769"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yang Zhang","raw_affiliation_strings":["Shanghai Key Laboratory of Chemical Biology & School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P. R. China"],"raw_orcid":"https://orcid.org/0000-0002-6804-1840","affiliations":[{"raw_affiliation_string":"Shanghai Key Laboratory of Chemical Biology & School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P. R. China","institution_ids":["https://openalex.org/I143593769"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070364011","display_name":"Xiaoyong Xu","orcid":"https://orcid.org/0000-0001-9679-3153","observed_orcids":["https://orcid.org/0000-0001-9679-3153"]},"institutions":[{"id":"https://openalex.org/I143593769","display_name":"East China University of Science and Technology","ror":"https://ror.org/01vyrm377","country_code":"CN","type":"education","lineage":["https://openalex.org/I143593769"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoyong Xu","raw_affiliation_strings":["Shanghai Key Laboratory of Chemical Biology & School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P. R. China"],"raw_orcid":"https://orcid.org/0000-0001-9679-3153","affiliations":[{"raw_affiliation_string":"Shanghai Key Laboratory of Chemical Biology & School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P. R. China","institution_ids":["https://openalex.org/I143593769"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100428632","display_name":"Zhong Li","orcid":"https://orcid.org/0000-0001-6665-5040","observed_orcids":["https://orcid.org/0000-0001-6665-5040","https://orcid.org/0009-0009-6487-0009"]},"institutions":[{"id":"https://openalex.org/I143593769","display_name":"East China University of Science and Technology","ror":"https://ror.org/01vyrm377","country_code":"CN","type":"education","lineage":["https://openalex.org/I143593769"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhong Li","raw_affiliation_strings":["Shanghai Key Laboratory of Chemical Biology & School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P. R. China"],"raw_orcid":"https://orcid.org/0000-0001-6665-5040","affiliations":[{"raw_affiliation_string":"Shanghai Key Laboratory of Chemical Biology & School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P. R. China","institution_ids":["https://openalex.org/I143593769"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071591600","display_name":"Wu\u2010Lin Yang","orcid":"https://orcid.org/0000-0001-7985-5017","observed_orcids":["https://orcid.org/0000-0001-7985-5017"]},"institutions":[{"id":"https://openalex.org/I143593769","display_name":"East China University of Science and Technology","ror":"https://ror.org/01vyrm377","country_code":"CN","type":"education","lineage":["https://openalex.org/I143593769"]},{"id":"https://openalex.org/I178232147","display_name":"Guizhou University","ror":"https://ror.org/02wmsc916","country_code":"CN","type":"education","lineage":["https://openalex.org/I178232147"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wu-Lin Yang","raw_affiliation_strings":["Guizhou University","Shanghai Key Laboratory of Chemical Biology & School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P. R. China","State Key Laboratory of Green Pesticide"],"raw_orcid":"https://orcid.org/0000-0001-7985-5017","affiliations":[{"raw_affiliation_string":"Guizhou University","institution_ids":["https://openalex.org/I178232147"]},{"raw_affiliation_string":"Shanghai Key Laboratory of Chemical Biology & School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P. R. China","institution_ids":["https://openalex.org/I143593769"]},{"raw_affiliation_string":"State Key Laboratory of Green Pesticide","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":1.1147,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.74043383,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"73","issue":"41","first_page":"25823","last_page":"25834"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14099","display_name":"Synthesis and Characterization of Heterocyclic Compounds","score":0.19689999520778656,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T14099","display_name":"Synthesis and Characterization of Heterocyclic Compounds","score":0.19689999520778656,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11180","display_name":"Pesticide and Herbicide Environmental Studies","score":0.17579999566078186,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13265","display_name":"Synthesis of Tetrazole Derivatives","score":0.09239999949932098,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/spirotetramat","display_name":"spirotetramat","score":0.8140000104904175},{"id":"https://openalex.org/keywords/systemic-translocation","display_name":"systemic translocation","score":0.7440000176429749},{"id":"https://openalex.org/keywords/aquatic-toxicity","display_name":"aquatic toxicity","score":0.6809999942779541},{"id":"https://openalex.org/keywords/eco-friendly-pesticides","display_name":"environmentally friendly pesticides","score":0.8360000252723694},{"id":"https://openalex.org/keywords/structure-activity-relationship","display_name":"structure-activity relationship","score":0.6159999966621399}],"concepts":[{"id":"https://openalex.org/C104488531","wikidata":"https://www.wikidata.org/wiki/Q864212","display_name":"Bioassay","level":2,"score":0.8105999827384949},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7687000036239624},{"id":"https://openalex.org/C74714110","wikidata":"https://www.wikidata.org/wiki/Q416014","display_name":"Acaricide","level":2,"score":0.5138000249862671},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.4885999858379364},{"id":"https://openalex.org/C116073593","wikidata":"https://www.wikidata.org/wiki/Q864491","display_name":"Biological activity","level":3,"score":0.4474000036716461},{"id":"https://openalex.org/C161176658","wikidata":"https://www.wikidata.org/wiki/Q131656","display_name":"Pesticide","level":2,"score":0.41100001335144043},{"id":"https://openalex.org/C53105671","wikidata":"https://www.wikidata.org/wiki/Q14777816","display_name":"Rational design","level":2,"score":0.32820001244544983},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.31310001015663147},{"id":"https://openalex.org/C193042331","wikidata":"https://www.wikidata.org/wiki/Q1772003","display_name":"Structure\u2013activity relationship","level":3,"score":0.30410000681877136},{"id":"https://openalex.org/C175528265","wikidata":"https://www.wikidata.org/wiki/Q500256","display_name":"Chemical structure","level":2,"score":0.30399999022483826},{"id":"https://openalex.org/C2777752112","wikidata":"https://www.wikidata.org/wiki/Q903238","display_name":"Lead compound","level":3,"score":0.2703999876976013},{"id":"https://openalex.org/C50027330","wikidata":"https://www.wikidata.org/wiki/Q908086","display_name":"Electrophile","level":3,"score":0.25949999690055847},{"id":"https://openalex.org/C2776612806","wikidata":"https://www.wikidata.org/wiki/Q59078","display_name":"Lactone","level":2,"score":0.2565999925136566}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001042","descriptor_name":"Aphids","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006540","descriptor_name":"Herbicides","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D006540","descriptor_name":"Herbicides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D006540","descriptor_name":"Herbicides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D007306","descriptor_name":"Insecticides","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":true},{"descriptor_ui":"D007306","descriptor_name":"Insecticides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D007306","descriptor_name":"Insecticides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011760","descriptor_name":"Pyrrolidinones","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":true},{"descriptor_ui":"D011760","descriptor_name":"Pyrrolidinones","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D011760","descriptor_name":"Pyrrolidinones","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013141","descriptor_name":"Spiro Compounds","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":true},{"descriptor_ui":"D013141","descriptor_name":"Spiro Compounds","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D013141","descriptor_name":"Spiro Compounds","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013329","descriptor_name":"Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015027","descriptor_name":"Zebrafish","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D040102","descriptor_name":"Tetranychidae","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D056810","descriptor_name":"Acaricides","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":true},{"descriptor_ui":"D056810","descriptor_name":"Acaricides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D056810","descriptor_name":"Acaricides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D057685","descriptor_name":"Plant Weeds","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1021/acs.jafc.5c06978","doi":"https://doi.org/10.1021/acs.jafc.5c06978","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.jafc.5c06978","pdf_url":null,"source":{"id":"https://openalex.org/S134644764","display_name":"Journal of Agricultural and Food Chemistry","issn_l":"0021-8561","issn":["0021-8561","1520-5118"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Agricultural and Food Chemistry","raw_type":"journal-article"},{"id":"pmid:41032356","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41032356","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of agricultural and food chemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2157186995","display_name":null,"funder_award_id":"23QA1402600","funder_id":"https://openalex.org/F4320327803","funder_display_name":"Shanghai Rising-Star Program"},{"id":"https://openalex.org/G2965588693","display_name":null,"funder_award_id":"22477027","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5445781367","display_name":"\u7c7b\u519c\u836f\u624b\u6027\u87ba\u73af\u5206\u5b50\u7684\u8bbe\u8ba1\u5408\u6210\u4e0e\u751f\u7269\u6d3b\u6027\u7814\u7a76","funder_award_id":"23ZR1416700","funder_id":"https://openalex.org/F4320309612","funder_display_name":"Natural Science Foundation of Shanghai"},{"id":"https://openalex.org/G6868234038","display_name":null,"funder_award_id":"22171081","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320309612","display_name":"Natural Science Foundation of Shanghai","ror":null},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320327803","display_name":"Shanghai Rising-Star Program","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":61,"referenced_works":["https://openalex.org/W1975879293","https://openalex.org/W1978183322","https://openalex.org/W2028841221","https://openalex.org/W2033218810","https://openalex.org/W2036244516","https://openalex.org/W2043256071","https://openalex.org/W2046350800","https://openalex.org/W2056319662","https://openalex.org/W2058504672","https://openalex.org/W2062993168","https://openalex.org/W2063263896","https://openalex.org/W2105488294","https://openalex.org/W2121960635","https://openalex.org/W2134721290","https://openalex.org/W2172496848","https://openalex.org/W2331573690","https://openalex.org/W2510775794","https://openalex.org/W2765290761","https://openalex.org/W2790682045","https://openalex.org/W2800060807","https://openalex.org/W2847803028","https://openalex.org/W2903126036","https://openalex.org/W2915839774","https://openalex.org/W2947578150","https://openalex.org/W2949430598","https://openalex.org/W2970004316","https://openalex.org/W2977471115","https://openalex.org/W3000730421","https://openalex.org/W3013678850","https://openalex.org/W3034358787","https://openalex.org/W3087100102","https://openalex.org/W3118559556","https://openalex.org/W3131073682","https://openalex.org/W3144998125","https://openalex.org/W3161339418","https://openalex.org/W4223969778","https://openalex.org/W4292787088","https://openalex.org/W4310958316","https://openalex.org/W4312112245","https://openalex.org/W4317433995","https://openalex.org/W4319057687","https://openalex.org/W4362506130","https://openalex.org/W4362692654","https://openalex.org/W4384563512","https://openalex.org/W4386917589","https://openalex.org/W4386964812","https://openalex.org/W4387618612","https://openalex.org/W4388486293","https://openalex.org/W4390238364","https://openalex.org/W4392284461","https://openalex.org/W4397022518","https://openalex.org/W4399724307","https://openalex.org/W4401285600","https://openalex.org/W4401610884","https://openalex.org/W4402732217","https://openalex.org/W4402990456","https://openalex.org/W4403359836","https://openalex.org/W4404599445","https://openalex.org/W4406770969","https://openalex.org/W4408098843","https://openalex.org/W4410456315"],"related_works":["https://openalex.org/W2375703007","https://openalex.org/W1975879293","https://openalex.org/W2028841221","https://openalex.org/W3110145109","https://openalex.org/W2391295490","https://openalex.org/W4401809355","https://openalex.org/W2393140530","https://openalex.org/W4310958316","https://openalex.org/W3133287405","https://openalex.org/W2349507659"],"abstract_inverted_index":{"have":[0],"systemic":[1],"translocation":[2],"similar":[3],"to":[4],"that":[5],"of":[6,14,30,43],"spirotetramat.":[7],"This":[8],"study":[9],"successfully":[10],"developed":[11],"a":[12,37],"series":[13],"spirocyclic":[15],"tetramic":[16],"acid":[17],"derivatives":[18],"with":[19],"high":[20],"bioactivity":[21],"and":[22],"lower":[23],"aquatic":[24],"toxicity":[25],"through":[26],"the":[27,31,41],"rational":[28],"incorporation":[29],"SCN":[32],"group.":[33],"The":[34],"findings":[35],"provide":[36],"valuable":[38],"approach":[39],"for":[40],"innovation":[42],"environmentally":[44],"friendly":[45],"pesticide":[46],"molecules.":[47]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2025-10-10T00:00:00"}