{"id":"https://openalex.org/W4414625697","doi":"https://doi.org/10.1177/20552076251376534","title":"Efficacy and feasibility of virtual reality-based cognitive tele-rehabilitation in Parkinson's disease: A pilot randomized controlled trial on patients and caregivers","display_name":"Efficacy and feasibility of virtual reality-based cognitive tele-rehabilitation in Parkinson's disease: A pilot randomized controlled trial on patients and caregivers","publication_year":2025,"publication_date":"2025-05-01","ids":{"openalex":"https://openalex.org/W4414625697","doi":"https://doi.org/10.1177/20552076251376534","pmid":"https://pubmed.ncbi.nlm.nih.gov/41018508","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12464430"},"language":"en","primary_location":{"id":"doi:10.1177/20552076251376534","doi":"https://doi.org/10.1177/20552076251376534","is_oa":true,"landing_page_url":"https://doi.org/10.1177/20552076251376534","pdf_url":null,"source":{"id":"https://openalex.org/S4210188408","display_name":"Digital Health","issn_l":"2055-2076","issn":["2055-2076"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"DIGITAL HEALTH","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1177/20552076251376534","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112149450","display_name":"Maria Grazia Maggio","orcid":"https://orcid.org/0000-0003-0757-2389","observed_orcids":["https://orcid.org/0000-0003-0757-2389"]},"institutions":[{"id":"https://openalex.org/I4210162269","display_name":"Centro Neurolesi Bonino Pulejo","ror":"https://ror.org/05tzq2c96","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210162269"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Maria Grazia Maggio","raw_affiliation_strings":["IRCCS Centro Neurolesi Bonino Pulejo, Messina, Italy"],"raw_orcid":"https://orcid.org/0000-0003-0757-2389","affiliations":[{"raw_affiliation_string":"IRCCS Centro Neurolesi Bonino Pulejo, Messina, Italy","institution_ids":["https://openalex.org/I4210162269"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046539221","display_name":"Amelia Rizzo","orcid":"https://orcid.org/0000-0002-6229-6463","observed_orcids":["https://orcid.org/0000-0002-6229-6463"]},"institutions":[{"id":"https://openalex.org/I112862951","display_name":"University of Messina","ror":"https://ror.org/05ctdxz19","country_code":"IT","type":"education","lineage":["https://openalex.org/I112862951"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Amelia Rizzo","raw_affiliation_strings":["Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy","institution_ids":["https://openalex.org/I112862951"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078064235","display_name":"Alessandra Benenati","orcid":"https://orcid.org/0000-0001-8303-8386","observed_orcids":["https://orcid.org/0000-0001-8303-8386"]},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alessandra Benenati","raw_affiliation_strings":["Department of Psychology \u201cRenzo Canestrari\u201d, University of Bologna, Bologna, Italy"],"raw_orcid":"https://orcid.org/0000-0001-8303-8386","affiliations":[{"raw_affiliation_string":"Department of Psychology \u201cRenzo Canestrari\u201d, University of Bologna, Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056410000","display_name":"Fabio Mauro Giamb\u00f2","orcid":"https://orcid.org/0000-0001-6843-4153","observed_orcids":["https://orcid.org/0000-0001-6843-4153"]},"institutions":[{"id":"https://openalex.org/I4210162269","display_name":"Centro Neurolesi Bonino Pulejo","ror":"https://ror.org/05tzq2c96","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210162269"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Fabio Giamb\u00f2 Mauro","raw_affiliation_strings":["IRCCS Centro Neurolesi Bonino Pulejo, Messina, Italy"],"raw_orcid":"https://orcid.org/0000-0001-6843-4153","affiliations":[{"raw_affiliation_string":"IRCCS Centro Neurolesi Bonino Pulejo, Messina, Italy","institution_ids":["https://openalex.org/I4210162269"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Antonino Cannav\u00f2","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210139630","display_name":"Azienda Ospedaliera Universitaria Policlinico \"G. Martino\"","ror":"https://ror.org/03tf96d34","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210139630"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Antonino Cannav\u00f2","raw_affiliation_strings":["A.O.U. Policlinico \u201cG. Martino\u201d, Messina, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"A.O.U. Policlinico \u201cG. Martino\u201d, Messina, Italy","institution_ids":["https://openalex.org/I4210139630"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079912600","display_name":"Paolo De Pasquale","orcid":"https://orcid.org/0000-0003-1688-2151","observed_orcids":["https://orcid.org/0000-0003-1688-2151"]},"institutions":[{"id":"https://openalex.org/I4210162269","display_name":"Centro Neurolesi Bonino Pulejo","ror":"https://ror.org/05tzq2c96","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210162269"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Paolo De Pasquale","raw_affiliation_strings":["IRCCS Centro Neurolesi Bonino Pulejo, Messina, Italy"],"raw_orcid":"https://orcid.org/0000-0003-1688-2151","affiliations":[{"raw_affiliation_string":"IRCCS Centro Neurolesi Bonino Pulejo, Messina, Italy","institution_ids":["https://openalex.org/I4210162269"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079596435","display_name":"Rosaria De Luca","orcid":"https://orcid.org/0000-0001-9503-4366","observed_orcids":["https://orcid.org/0000-0001-9503-4366","https://orcid.org/0000-0002-3905-9486"]},"institutions":[{"id":"https://openalex.org/I4210162269","display_name":"Centro Neurolesi Bonino Pulejo","ror":"https://ror.org/05tzq2c96","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210162269"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Rosaria De Luca","raw_affiliation_strings":["IRCCS Centro Neurolesi Bonino Pulejo, Messina, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IRCCS Centro Neurolesi Bonino Pulejo, Messina, Italy","institution_ids":["https://openalex.org/I4210162269"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088210421","display_name":"Angelo Quartarone","orcid":"https://orcid.org/0000-0003-1485-6590","observed_orcids":["https://orcid.org/0000-0003-1485-6590"]},"institutions":[{"id":"https://openalex.org/I4210162269","display_name":"Centro Neurolesi Bonino Pulejo","ror":"https://ror.org/05tzq2c96","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210162269"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Angelo Quartarone","raw_affiliation_strings":["IRCCS Centro Neurolesi Bonino Pulejo, Messina, Italy"],"raw_orcid":"https://orcid.org/0000-0003-1485-6590","affiliations":[{"raw_affiliation_string":"IRCCS Centro Neurolesi Bonino Pulejo, Messina, Italy","institution_ids":["https://openalex.org/I4210162269"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5066306966","display_name":"Rocco Salvatore Calabr\u00f2","orcid":"https://orcid.org/0000-0002-8566-3166","observed_orcids":["https://orcid.org/0000-0002-8566-3166"]},"institutions":[{"id":"https://openalex.org/I4210162269","display_name":"Centro Neurolesi Bonino Pulejo","ror":"https://ror.org/05tzq2c96","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4210162269"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Rocco Salvatore Calabr\u00f2","raw_affiliation_strings":["IRCCS Centro Neurolesi Bonino Pulejo, Messina, Italy"],"raw_orcid":"https://orcid.org/0000-0002-8566-3166","affiliations":[{"raw_affiliation_string":"IRCCS Centro Neurolesi Bonino Pulejo, Messina, Italy","institution_ids":["https://openalex.org/I4210162269"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5046539221","https://openalex.org/A5112149450"],"corresponding_institution_ids":["https://openalex.org/I112862951","https://openalex.org/I4210162269"],"apc_list":{"value":2000,"currency":"USD","value_usd":2000},"apc_paid":{"value":2000,"currency":"USD","value_usd":2000},"fwci":4.479,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.94860018,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"11","issue":null,"first_page":"20552076251376534","last_page":"20552076251376534"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.361299991607666,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.361299991607666,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10912","display_name":"Telemedicine and Telehealth Implementation","score":0.2858999967575073,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.16429999470710754,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":1.0},{"id":"https://openalex.org/keywords/virtual-reality","display_name":"virtual reality","score":0.9639999866485596},{"id":"https://openalex.org/keywords/cognitive-decline","display_name":"cognitive decline","score":0.7590000033378601},{"id":"https://openalex.org/keywords/caregiver-burden","display_name":"caregiver burden","score":0.6940000057220459},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.9480000138282776},{"id":"https://openalex.org/keywords/cognitive-training","display_name":"cognitive training","score":0.6890000104904175},{"id":"https://openalex.org/keywords/home-based-rehabilitation","display_name":"home-based rehabilitation","score":0.8270000219345093},{"id":"https://openalex.org/keywords/usability","display_name":"usability","score":0.800000011920929},{"id":"https://openalex.org/keywords/montreal-cognitive-assessment","display_name":"Montreal Cognitive Assessment","score":0.7960000038146973},{"id":"https://openalex.org/keywords/parkinson-s-disease-questionnaire","display_name":"Parkinson's Disease Questionnaire","score":0.8159999847412109}],"concepts":[{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.6786999702453613},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.6571000218391418},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6377999782562256},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.5465999841690063},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.5146999955177307},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.46459999680519104},{"id":"https://openalex.org/C2994577977","wikidata":"https://www.wikidata.org/wiki/Q1203526","display_name":"Pilot trial","level":3,"score":0.3402000069618225},{"id":"https://openalex.org/C26517878","wikidata":"https://www.wikidata.org/wiki/Q228039","display_name":"Key (lock)","level":2,"score":0.3190999925136566},{"id":"https://openalex.org/C2779530757","wikidata":"https://www.wikidata.org/wiki/Q1207505","display_name":"Quality (philosophy)","level":2,"score":0.3091999888420105},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.29339998960494995},{"id":"https://openalex.org/C68015696","wikidata":"https://www.wikidata.org/wiki/Q5141235","display_name":"Cognitive rehabilitation therapy","level":3,"score":0.2741999924182892},{"id":"https://openalex.org/C2776035688","wikidata":"https://www.wikidata.org/wiki/Q1606558","display_name":"Affect (linguistics)","level":2,"score":0.2718000113964081}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1177/20552076251376534","doi":"https://doi.org/10.1177/20552076251376534","is_oa":true,"landing_page_url":"https://doi.org/10.1177/20552076251376534","pdf_url":null,"source":{"id":"https://openalex.org/S4210188408","display_name":"Digital Health","issn_l":"2055-2076","issn":["2055-2076"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"DIGITAL HEALTH","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12464430","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12464430/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12464430/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Digit Health","raw_type":"Text"},{"id":"pmh:oai:europepmc.org:11272774","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12464430","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:41018508","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41018508","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Digital health","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:527439b25d0e441b99de78a6352ddc47","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/527439b25d0e441b99de78a6352ddc47","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Digital Health, Vol 11 (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1177/20552076251376534","doi":"https://doi.org/10.1177/20552076251376534","is_oa":true,"landing_page_url":"https://doi.org/10.1177/20552076251376534","pdf_url":null,"source":{"id":"https://openalex.org/S4210188408","display_name":"Digital Health","issn_l":"2055-2076","issn":["2055-2076"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"DIGITAL HEALTH","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[{"id":"https://openalex.org/G2559710702","display_name":null,"funder_award_id":"WFR: GR-2016-02361306","funder_id":"https://openalex.org/F4320321781","funder_display_name":"Ministero della Salute"}],"funders":[{"id":"https://openalex.org/F4320321781","display_name":"Ministero della Salute","ror":"https://ror.org/00789fa95"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4414625697.pdf","grobid_xml":"https://content.openalex.org/works/W4414625697.grobid-xml"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W1972349970","https://openalex.org/W1984768353","https://openalex.org/W1991447140","https://openalex.org/W2006521806","https://openalex.org/W2008560062","https://openalex.org/W2085838792","https://openalex.org/W2115358230","https://openalex.org/W2143342727","https://openalex.org/W2145954079","https://openalex.org/W2147111512","https://openalex.org/W2163645531","https://openalex.org/W2165137024","https://openalex.org/W2165758561","https://openalex.org/W2593272776","https://openalex.org/W2622784527","https://openalex.org/W2622900209","https://openalex.org/W2788752483","https://openalex.org/W2789755215","https://openalex.org/W2997120956","https://openalex.org/W3049466187","https://openalex.org/W3162056152","https://openalex.org/W3185920825","https://openalex.org/W4206892710","https://openalex.org/W4281654484","https://openalex.org/W4283032327","https://openalex.org/W4297460332","https://openalex.org/W4306403359","https://openalex.org/W4389049818","https://openalex.org/W4390064700","https://openalex.org/W4390947792","https://openalex.org/W4391841613","https://openalex.org/W4395070613","https://openalex.org/W4396955116","https://openalex.org/W4400283968","https://openalex.org/W4400582331","https://openalex.org/W4400764326","https://openalex.org/W4400815759","https://openalex.org/W4400875070","https://openalex.org/W4401335104","https://openalex.org/W4401357546"],"related_works":["https://openalex.org/W4390064700","https://openalex.org/W4414569777","https://openalex.org/W2898351579","https://openalex.org/W4319344719","https://openalex.org/W2889281238","https://openalex.org/W4296042408","https://openalex.org/W4297826770","https://openalex.org/W4297460332","https://openalex.org/W7164210408","https://openalex.org/W4400679899"],"abstract_inverted_index":{"Objective":[0],"Parkinson's":[1],"disease":[2],"(PD)":[3],"is":[4],"a":[5,96,113,190,217,279],"progressive":[6],"neurodegenerative":[7],"disorder":[8],"that":[9,254],"not":[10,208],"only":[11],"impairs":[12],"motor":[13],"functions":[14],"but":[15,206],"also":[16,173],"may":[17],"lead":[18],"to":[19,38,54,94,189,226],"significant":[20,144,234],"cognitive":[21,46,61,102,110,148,255,267],"decline,":[22],"greatly":[23],"affecting":[24],"the":[25,40,68,123,169,194,223,227,239,242,289],"quality":[26,63,158,270],"of":[27,45,64,159,213,271],"life":[28,160,272],"for":[29],"both":[30,204],"patients":[31,74,86,275],"and":[32,42,67,87,121,157,182,246,269,276],"their":[33,88],"caregivers.":[34,292],"This":[35],"study":[36],"aims":[37],"evaluate":[39],"feasibility":[41],"potential":[43],"effectiveness":[44],"tele-rehabilitation":[47],"(TR)":[48],"plus":[49],"virtual":[50],"reality":[51],"(VR),":[52],"compared":[53,225],"traditional":[55,101],"home-based":[56],"rehabilitation":[57,115],"methods,":[58],"focusing":[59],"on":[60,70,291],"outcomes,":[62],"life,":[65],"usability,":[66],"impact":[69],"caregiver":[71,199],"strain":[72],"in":[73,146,168,176,198,203,222,241,265,273,282],"with":[75,117,260],"PD.":[76],"Methods":[77],"In":[78],"this":[79],"pilot":[80],"randomized":[81],"controlled":[82],"trial,":[83],"20":[84],"PD":[85,274,284],"primary":[89],"caregivers":[90],"were":[91,236],"randomly":[92],"assigned":[93],"either":[95],"control":[97],"group":[98,107],"(CG)":[99],"receiving":[100],"training":[103],"or":[104],"an":[105],"experimental":[106],"(EG)":[108],"undergoing":[109],"TR":[111,127],"using":[112],"VR":[114],"system,":[116],"assessments":[118],"conducted":[119],"before":[120],"after":[122],"8-week":[124],"intervention.":[125],"Results":[126],"was":[128,201],"rated":[129],"as":[130],"highly":[131],"usable":[132],"(System":[133],"Usability":[134],"Scale":[135],"mean":[136],"score:":[137],"84.3":[138],"\u00b1":[139],"9.5).":[140],"Post-intervention":[141],"analyses":[142],"showed":[143,174],"improvements":[145,175],"global":[147],"functioning":[149],"(Montreal":[150],"Cognitive":[151],"Assessment":[152],"(MoCA):":[153],"p":[154,165,179,185,230],"=":[155,166,180,186,231],"0.002)":[156,167],"(Parkinson's":[161],"Disease":[162],"Questionnaire":[163,245],"(PDQ)-8:":[164],"EG.":[170,195],"The":[171],"CG":[172,228],"MoCA":[177,220],"(":[178,184,229],"0.008)":[181],"PDQ-8":[183,247],"0.016),":[187],"although":[188],"lesser":[191],"extent":[192],"than":[193],"A":[196],"reduction":[197],"burden":[200,290],"observed":[202],"groups":[205,240],"did":[207],"reach":[209],"statistical":[210],"significance.":[211],"Analysis":[212],"\u0394":[214,248],"scores":[215],"revealed":[216],"significantly":[218],"greater":[219],"improvement":[221],"EG":[224],"0.019).":[232],"Statistically":[233],"differences":[235],"found":[237],"between":[238],"Family":[243],"Strain":[244],"scores.":[249],"Conclusion":[250],"These":[251],"findings":[252],"suggest":[253],"TR,":[256],"particularly":[257],"when":[258],"integrated":[259],"VR,":[261],"might":[262],"be":[263],"useful":[264],"improving":[266],"function":[268],"could":[277],"play":[278],"key":[280],"role":[281],"future":[283],"management":[285],"strategies,":[286],"potentially":[287],"easing":[288]},"counts_by_year":[{"year":2026,"cited_by_count":9}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2025-10-10T00:00:00"}