{"id":"https://openalex.org/W4414518902","doi":"https://doi.org/10.1016/j.phytochem.2025.114685","title":"Isolation, characterization, and anti-neuroinflammatory activity of sesquiterpenoids from Pogostemon esquirolii","display_name":"Isolation, characterization, and anti-neuroinflammatory activity of sesquiterpenoids from Pogostemon esquirolii","publication_year":2025,"publication_date":"2025-09-25","ids":{"openalex":"https://openalex.org/W4414518902","doi":"https://doi.org/10.1016/j.phytochem.2025.114685","pmid":"https://pubmed.ncbi.nlm.nih.gov/41015069"},"language":"en","primary_location":{"id":"doi:10.1016/j.phytochem.2025.114685","doi":"https://doi.org/10.1016/j.phytochem.2025.114685","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.phytochem.2025.114685","pdf_url":null,"source":{"id":"https://openalex.org/S88226677","display_name":"Phytochemistry","issn_l":"0031-9422","issn":["0031-9422","1873-3700"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Phytochemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Yebi Qin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210151615","display_name":"Wuyi University","ror":"https://ror.org/0488wz367","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210151615"]},{"id":"https://openalex.org/I98834328","display_name":"Wuyi University","ror":"https://ror.org/059djzq42","country_code":"CN","type":"education","lineage":["https://openalex.org/I98834328"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yebi Qin","raw_affiliation_strings":["School of Pharmacy and Food Engineering, Wuyi University, Jiangmen, 529020, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy and Food Engineering, Wuyi University, Jiangmen, 529020, China","institution_ids":["https://openalex.org/I4210151615","https://openalex.org/I98834328"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xinyan Shao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210151615","display_name":"Wuyi University","ror":"https://ror.org/0488wz367","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210151615"]},{"id":"https://openalex.org/I98834328","display_name":"Wuyi University","ror":"https://ror.org/059djzq42","country_code":"CN","type":"education","lineage":["https://openalex.org/I98834328"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinyan Shao","raw_affiliation_strings":["School of Pharmacy and Food Engineering, Wuyi University, Jiangmen, 529020, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy and Food Engineering, Wuyi University, Jiangmen, 529020, China","institution_ids":["https://openalex.org/I4210151615","https://openalex.org/I98834328"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029270434","display_name":"Yinzheng Xie","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210151615","display_name":"Wuyi University","ror":"https://ror.org/0488wz367","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210151615"]},{"id":"https://openalex.org/I98834328","display_name":"Wuyi University","ror":"https://ror.org/059djzq42","country_code":"CN","type":"education","lineage":["https://openalex.org/I98834328"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yinzheng Xie","raw_affiliation_strings":["School of Pharmacy and Food Engineering, Wuyi University, Jiangmen, 529020, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy and Food Engineering, Wuyi University, Jiangmen, 529020, China","institution_ids":["https://openalex.org/I4210151615","https://openalex.org/I98834328"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hailin Lu","orcid":"https://orcid.org/0009-0000-7801-2966","observed_orcids":["https://orcid.org/0009-0000-7801-2966"]},"institutions":[{"id":"https://openalex.org/I4210151615","display_name":"Wuyi University","ror":"https://ror.org/0488wz367","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210151615"]},{"id":"https://openalex.org/I98834328","display_name":"Wuyi University","ror":"https://ror.org/059djzq42","country_code":"CN","type":"education","lineage":["https://openalex.org/I98834328"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hailin Lu","raw_affiliation_strings":["School of Pharmacy and Food Engineering, Wuyi University, Jiangmen, 529020, China"],"raw_orcid":"https://orcid.org/0009-0000-7801-2966","affiliations":[{"raw_affiliation_string":"School of Pharmacy and Food Engineering, Wuyi University, Jiangmen, 529020, China","institution_ids":["https://openalex.org/I4210151615","https://openalex.org/I98834328"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075306618","display_name":"Kaien Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210151615","display_name":"Wuyi University","ror":"https://ror.org/0488wz367","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210151615"]},{"id":"https://openalex.org/I98834328","display_name":"Wuyi University","ror":"https://ror.org/059djzq42","country_code":"CN","type":"education","lineage":["https://openalex.org/I98834328"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kaien Chen","raw_affiliation_strings":["School of Pharmacy and Food Engineering, Wuyi University, Jiangmen, 529020, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy and Food Engineering, Wuyi University, Jiangmen, 529020, China","institution_ids":["https://openalex.org/I4210151615","https://openalex.org/I98834328"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022457658","display_name":"Xi Zheng","orcid":"https://orcid.org/0000-0001-7522-631X","observed_orcids":["https://orcid.org/0000-0001-7522-631X"]},"institutions":[{"id":"https://openalex.org/I4210151615","display_name":"Wuyi University","ror":"https://ror.org/0488wz367","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210151615"]},{"id":"https://openalex.org/I98834328","display_name":"Wuyi University","ror":"https://ror.org/059djzq42","country_code":"CN","type":"education","lineage":["https://openalex.org/I98834328"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xi Zheng","raw_affiliation_strings":["School of Pharmacy and Food Engineering, Wuyi University, Jiangmen, 529020, China; International Healthcare Innovation Institute (Jiangmen), Jiangmen, 529040, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy and Food Engineering, Wuyi University, Jiangmen, 529020, China; International Healthcare Innovation Institute (Jiangmen), Jiangmen, 529040, China","institution_ids":["https://openalex.org/I4210151615","https://openalex.org/I98834328"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Guodong Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]},{"id":"https://openalex.org/I4210151615","display_name":"Wuyi University","ror":"https://ror.org/0488wz367","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210151615"]},{"id":"https://openalex.org/I98834328","display_name":"Wuyi University","ror":"https://ror.org/059djzq42","country_code":"CN","type":"education","lineage":["https://openalex.org/I98834328"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guodong Chen","raw_affiliation_strings":["School of Pharmacy and Food Engineering, Wuyi University, Jiangmen, 529020, China; College of Pharmacy, Jinan University, Guangzhou, 510632, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy and Food Engineering, Wuyi University, Jiangmen, 529020, China; College of Pharmacy, Jinan University, Guangzhou, 510632, China","institution_ids":["https://openalex.org/I159948400","https://openalex.org/I4210151615","https://openalex.org/I98834328"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090280140","display_name":"Li\u2010She Gan","orcid":"https://orcid.org/0000-0002-5688-5894","observed_orcids":["https://orcid.org/0000-0002-5688-5894","https://orcid.org/0009-0007-4274-9051"]},"institutions":[{"id":"https://openalex.org/I114539943","display_name":"Zhejiang Chinese Medical University","ror":"https://ror.org/04epb4p87","country_code":"CN","type":"education","lineage":["https://openalex.org/I114539943"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lishe Gan","raw_affiliation_strings":["College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, China","institution_ids":["https://openalex.org/I114539943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013361262","display_name":"Song Ang","orcid":"https://orcid.org/0000-0003-2497-9631","observed_orcids":["https://orcid.org/0000-0003-2497-9631"]},"institutions":[{"id":"https://openalex.org/I4210151615","display_name":"Wuyi University","ror":"https://ror.org/0488wz367","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210151615"]},{"id":"https://openalex.org/I98834328","display_name":"Wuyi University","ror":"https://ror.org/059djzq42","country_code":"CN","type":"education","lineage":["https://openalex.org/I98834328"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Song Ang","raw_affiliation_strings":["School of Pharmacy and Food Engineering, Wuyi University, Jiangmen, 529020, China; International Healthcare Innovation Institute (Jiangmen), Jiangmen, 529040, China. Electronic address: jnuangsong@126.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy and Food Engineering, Wuyi University, Jiangmen, 529020, China; International Healthcare Innovation Institute (Jiangmen), Jiangmen, 529040, China. Electronic address: jnuangsong@126.com","institution_ids":["https://openalex.org/I4210151615","https://openalex.org/I98834328"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029592503","display_name":"Dongli Li","orcid":"https://orcid.org/0000-0001-9955-2304","observed_orcids":["https://orcid.org/0000-0001-9955-2304"]},"institutions":[{"id":"https://openalex.org/I4210151615","display_name":"Wuyi University","ror":"https://ror.org/0488wz367","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210151615"]},{"id":"https://openalex.org/I98834328","display_name":"Wuyi University","ror":"https://ror.org/059djzq42","country_code":"CN","type":"education","lineage":["https://openalex.org/I98834328"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Dongli Li","raw_affiliation_strings":["School of Pharmacy and Food Engineering, Wuyi University, Jiangmen, 529020, China; International Healthcare Innovation Institute (Jiangmen), Jiangmen, 529040, China. Electronic address: wyuchemldl@126.com"],"raw_orcid":"https://orcid.org/0000-0001-9955-2304","affiliations":[{"raw_affiliation_string":"School of Pharmacy and Food Engineering, Wuyi University, Jiangmen, 529020, China; International Healthcare Innovation Institute (Jiangmen), Jiangmen, 529040, China. Electronic address: wyuchemldl@126.com","institution_ids":["https://openalex.org/I4210151615","https://openalex.org/I98834328"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5013361262","https://openalex.org/A5029592503"],"corresponding_institution_ids":["https://openalex.org/I4210151615","https://openalex.org/I98834328"],"apc_list":{"value":4350,"currency":"USD","value_usd":4350},"apc_paid":null,"fwci":0.2637,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.31700859,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"241","issue":null,"first_page":"114685","last_page":"114685"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11547","display_name":"Sesquiterpenes and Asteraceae Studies","score":0.8604000210762024,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11547","display_name":"Sesquiterpenes and Asteraceae Studies","score":0.8604000210762024,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11613","display_name":"Phytochemistry and Biological Activities","score":0.11410000175237656,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12685","display_name":"Phytochemical compounds biological activities","score":0.009200000204145908,"subfield":{"id":"https://openalex.org/subfields/3002","display_name":"Drug Discovery"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sesquiterpenes","display_name":"sesquiterpenes","score":0.996999979019165},{"id":"https://openalex.org/keywords/eudesmane-sesquiterpenoids","display_name":"eudesmane sesquiterpenes","score":0.8420000076293945},{"id":"https://openalex.org/keywords/bisabolane-sesquiterpenes","display_name":"bisabolane sesquiterpenes","score":0.9760000109672546},{"id":"https://openalex.org/keywords/anti-neuroinflammatory-activity","display_name":"anti-neuroinflammatory activity","score":0.8640000224113464},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":0.8669999837875366},{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"cognitive impairment","score":0.7979999780654907},{"id":"https://openalex.org/keywords/microglia","display_name":"microglia","score":0.703000009059906},{"id":"https://openalex.org/keywords/bv2-cells","display_name":"BV-2 cells","score":0.6970000267028809},{"id":"https://openalex.org/keywords/nitric-oxide-production","display_name":"nitric oxide production","score":0.6890000104904175},{"id":"https://openalex.org/keywords/tnf-signaling","display_name":"TNF signaling","score":0.9480000138282776},{"id":"https://openalex.org/keywords/nf-kappab-signaling","display_name":"NF-\u03baB signaling","score":0.7590000033378601},{"id":"https://openalex.org/keywords/mapk-signaling","display_name":"MAPK signaling","score":0.9959999918937683},{"id":"https://openalex.org/keywords/inducible-nitric-oxide-synthase","display_name":"inducible nitric oxide synthase","score":0.7770000100135803},{"id":"https://openalex.org/keywords/cyclooxygenase-2","display_name":"cyclooxygenase-2","score":0.984000027179718},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.8180000185966492},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.9990000128746033}],"concepts":[{"id":"https://openalex.org/C195475562","wikidata":"https://www.wikidata.org/wiki/Q1639139","display_name":"Phytochemical","level":2,"score":0.5737000107765198},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5461000204086304},{"id":"https://openalex.org/C85265743","wikidata":"https://www.wikidata.org/wiki/Q885458","display_name":"Blot","level":3,"score":0.47859999537467957},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.43560001254081726},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.42289999127388},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.39590001106262207},{"id":"https://openalex.org/C57074206","wikidata":"https://www.wikidata.org/wiki/Q14197552","display_name":"MAPK/ERK pathway","level":3,"score":0.39329999685287476},{"id":"https://openalex.org/C193042331","wikidata":"https://www.wikidata.org/wiki/Q1772003","display_name":"Structure\u2013activity relationship","level":3,"score":0.3894999921321869},{"id":"https://openalex.org/C116073593","wikidata":"https://www.wikidata.org/wiki/Q864491","display_name":"Biological activity","level":3,"score":0.387800008058548},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.3727000057697296},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3702000081539154},{"id":"https://openalex.org/C2778816929","wikidata":"https://www.wikidata.org/wiki/Q22676679","display_name":"Acetylcholinesterase","level":3,"score":0.36579999327659607},{"id":"https://openalex.org/C2777752112","wikidata":"https://www.wikidata.org/wiki/Q903238","display_name":"Lead compound","level":3,"score":0.35989999771118164},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.3582000136375427},{"id":"https://openalex.org/C104264131","wikidata":"https://www.wikidata.org/wiki/Q898637","display_name":"Isopropyl","level":2,"score":0.3379000127315521},{"id":"https://openalex.org/C206103511","wikidata":"https://www.wikidata.org/wiki/Q426694","display_name":"Terpenoid","level":2,"score":0.3292999863624573},{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.29899999499320984},{"id":"https://openalex.org/C2777667214","wikidata":"https://www.wikidata.org/wiki/Q70702","display_name":"Alkaloid","level":2,"score":0.29829999804496765},{"id":"https://openalex.org/C41685203","wikidata":"https://www.wikidata.org/wiki/Q1974042","display_name":"Docking (animal)","level":2,"score":0.29760000109672546},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2964000105857849},{"id":"https://openalex.org/C2779703632","wikidata":"https://www.wikidata.org/wiki/Q581996","display_name":"Anti-inflammatory","level":2,"score":0.2962999939918518},{"id":"https://openalex.org/C2777066959","wikidata":"https://www.wikidata.org/wiki/Q869711","display_name":"Cricetulus","level":4,"score":0.2957000136375427},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.28529998660087585},{"id":"https://openalex.org/C175528265","wikidata":"https://www.wikidata.org/wiki/Q500256","display_name":"Chemical structure","level":2,"score":0.26350000500679016},{"id":"https://openalex.org/C2777730290","wikidata":"https://www.wikidata.org/wiki/Q411114","display_name":"NF-\u03baB","level":3,"score":0.25760000944137573},{"id":"https://openalex.org/C2778609962","wikidata":"https://www.wikidata.org/wiki/Q424567","display_name":"Apigenin","level":4,"score":0.25699999928474426},{"id":"https://openalex.org/C166342909","wikidata":"https://www.wikidata.org/wiki/Q845326","display_name":"Allosteric regulation","level":3,"score":0.2567000091075897},{"id":"https://openalex.org/C2991691389","wikidata":"https://www.wikidata.org/wiki/Q901227","display_name":"Active compound","level":2,"score":0.25189998745918274},{"id":"https://openalex.org/C2776211264","wikidata":"https://www.wikidata.org/wiki/Q80218","display_name":"Sesquiterpene","level":2,"score":0.2513999938964844}],"mesh":[{"descriptor_ui":"D000070177","descriptor_name":"Pogostemon","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000893","descriptor_name":"Anti-Inflammatory Agents","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D000893","descriptor_name":"Anti-Inflammatory Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000893","descriptor_name":"Anti-Inflammatory Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008070","descriptor_name":"Lipopolysaccharides","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D008070","descriptor_name":"Lipopolysaccharides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D009569","descriptor_name":"Nitric Oxide","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D009569","descriptor_name":"Nitric Oxide","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D012717","descriptor_name":"Sesquiterpenes","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D012717","descriptor_name":"Sesquiterpenes","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D012717","descriptor_name":"Sesquiterpenes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013329","descriptor_name":"Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017628","descriptor_name":"Microglia","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017628","descriptor_name":"Microglia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D052247","descriptor_name":"Nitric Oxide Synthase Type II","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D052247","descriptor_name":"Nitric Oxide Synthase Type II","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.phytochem.2025.114685","doi":"https://doi.org/10.1016/j.phytochem.2025.114685","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.phytochem.2025.114685","pdf_url":null,"source":{"id":"https://openalex.org/S88226677","display_name":"Phytochemistry","issn_l":"0031-9422","issn":["0031-9422","1873-3700"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Phytochemistry","raw_type":"journal-article"},{"id":"pmid:41015069","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41015069","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Phytochemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.766700029373169,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2012858464","display_name":null,"funder_award_id":"2023A 1515012904","funder_id":"https://openalex.org/F4320337111","funder_display_name":"Basic and Applied Basic Research Foundation of Guangdong Province"},{"id":"https://openalex.org/G2065797488","display_name":null,"funder_award_id":"50917003M9","funder_id":"https://openalex.org/F4320324310","funder_display_name":"Wuyi University"},{"id":"https://openalex.org/G2852801333","display_name":null,"funder_award_id":"50917003M7","funder_id":"https://openalex.org/F4320324310","funder_display_name":"Wuyi University"},{"id":"https://openalex.org/G3665737029","display_name":null,"funder_award_id":"2024AL004","funder_id":"https://openalex.org/F4320324310","funder_display_name":"Wuyi University"},{"id":"https://openalex.org/G6144234409","display_name":null,"funder_award_id":"2022ZDJS025","funder_id":"https://openalex.org/F4320326279","funder_display_name":"Department of Education of Guangdong Province"},{"id":"https://openalex.org/G7230402242","display_name":null,"funder_award_id":"82304323","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320324310","display_name":"Wuyi University","ror":"https://ror.org/059djzq42"},{"id":"https://openalex.org/F4320326279","display_name":"Department of Education of Guangdong Province","ror":"https://ror.org/01s5gyw91"},{"id":"https://openalex.org/F4320337111","display_name":"Basic and Applied Basic Research Foundation of Guangdong Province","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":49,"referenced_works":["https://openalex.org/W136786583","https://openalex.org/W1993127675","https://openalex.org/W1998367040","https://openalex.org/W2032927302","https://openalex.org/W2034370172","https://openalex.org/W2034993097","https://openalex.org/W2066113694","https://openalex.org/W2116240218","https://openalex.org/W2126393924","https://openalex.org/W2190558971","https://openalex.org/W2291832248","https://openalex.org/W2343614482","https://openalex.org/W2599130782","https://openalex.org/W2800644838","https://openalex.org/W2898293688","https://openalex.org/W2900569176","https://openalex.org/W2978447974","https://openalex.org/W2998621054","https://openalex.org/W3005184394","https://openalex.org/W3106141462","https://openalex.org/W3118034802","https://openalex.org/W3120310112","https://openalex.org/W3197263472","https://openalex.org/W4200395105","https://openalex.org/W4205979221","https://openalex.org/W4221003204","https://openalex.org/W4283212522","https://openalex.org/W4285590961","https://openalex.org/W4293760954","https://openalex.org/W4315776736","https://openalex.org/W4317778375","https://openalex.org/W4317871130","https://openalex.org/W4321368232","https://openalex.org/W4365514176","https://openalex.org/W4381893154","https://openalex.org/W4386368095","https://openalex.org/W4387408815","https://openalex.org/W4390805343","https://openalex.org/W4392301328","https://openalex.org/W4392884093","https://openalex.org/W4396717509","https://openalex.org/W4396860343","https://openalex.org/W4399704764","https://openalex.org/W4403479110","https://openalex.org/W4404511387","https://openalex.org/W4406401015","https://openalex.org/W4407767842","https://openalex.org/W4407767949","https://openalex.org/W7123339022"],"related_works":["https://openalex.org/W4200395105","https://openalex.org/W4416825289","https://openalex.org/W7124306019","https://openalex.org/W4293210895","https://openalex.org/W4294631778","https://openalex.org/W2889813394","https://openalex.org/W4402782153","https://openalex.org/W4372215117","https://openalex.org/W4386980651","https://openalex.org/W4408422537"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2025-10-10T00:00:00"}