{"id":"https://openalex.org/W4414224699","doi":"https://doi.org/10.1016/j.ijbiomac.2025.147712","title":"Temperature and time induced assembly phase changes of engineered spidroin protein solutions","display_name":"Temperature and time induced assembly phase changes of engineered spidroin protein solutions","publication_year":2025,"publication_date":"2025-09-16","ids":{"openalex":"https://openalex.org/W4414224699","doi":"https://doi.org/10.1016/j.ijbiomac.2025.147712","pmid":"https://pubmed.ncbi.nlm.nih.gov/40967530"},"language":"en","primary_location":{"id":"doi:10.1016/j.ijbiomac.2025.147712","doi":"https://doi.org/10.1016/j.ijbiomac.2025.147712","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ijbiomac.2025.147712","pdf_url":null,"source":{"id":"https://openalex.org/S83853393","display_name":"International Journal of Biological Macromolecules","issn_l":"0141-8130","issn":["0141-8130","1879-0003"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Biological Macromolecules","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.ijbiomac.2025.147712","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084231712","display_name":"Dmitry A. Tolmachev","orcid":"https://orcid.org/0000-0002-9699-100X","observed_orcids":["https://orcid.org/0000-0002-9699-100X"]},"institutions":[{"id":"https://openalex.org/I112281704","display_name":"Research Council of Finland","ror":"https://ror.org/05k73zm37","country_code":"FI","type":"government","lineage":["https://openalex.org/I112281704"]},{"id":"https://openalex.org/I9927081","display_name":"Aalto University","ror":"https://ror.org/020hwjq30","country_code":"FI","type":"education","lineage":["https://openalex.org/I9927081"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Dmitry Tolmachev","raw_affiliation_strings":["Department of Chemistry and Materials Science, Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland; Academy of Finland Center of Excellence in Life-Inspired Hybrid Materials (LIBER), Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Materials Science, Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland; Academy of Finland Center of Excellence in Life-Inspired Hybrid Materials (LIBER), Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland","institution_ids":["https://openalex.org/I112281704","https://openalex.org/I9927081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085698117","display_name":"Isabell Tunn","orcid":"https://orcid.org/0000-0003-0853-8908","observed_orcids":["https://orcid.org/0000-0003-0853-8908"]},"institutions":[{"id":"https://openalex.org/I112281704","display_name":"Research Council of Finland","ror":"https://ror.org/05k73zm37","country_code":"FI","type":"government","lineage":["https://openalex.org/I112281704"]},{"id":"https://openalex.org/I4210128116","display_name":"Fraunhofer Institute for Applied Polymer Research","ror":"https://ror.org/02yhs7m71","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210128116","https://openalex.org/I4923324"]},{"id":"https://openalex.org/I9927081","display_name":"Aalto University","ror":"https://ror.org/020hwjq30","country_code":"FI","type":"education","lineage":["https://openalex.org/I9927081"]}],"countries":["DE","FI"],"is_corresponding":false,"raw_author_name":"Isabell Tunn","raw_affiliation_strings":["Department of Bioproducts and Biosystems, Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland; Academy of Finland Center of Excellence in Life-Inspired Hybrid Materials (LIBER), Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland; Fraunhofer Institute for Applied Polymer Research (IAP), Geiselbergstra\u00dfe 69, 14476, Potsdam, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioproducts and Biosystems, Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland; Academy of Finland Center of Excellence in Life-Inspired Hybrid Materials (LIBER), Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland; Fraunhofer Institute for Applied Polymer Research (IAP), Geiselbergstra\u00dfe 69, 14476, Potsdam, Germany","institution_ids":["https://openalex.org/I112281704","https://openalex.org/I4210128116","https://openalex.org/I9927081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090749175","display_name":"Adam L. Harmat","orcid":"https://orcid.org/0000-0003-2776-8995","observed_orcids":["https://orcid.org/0000-0003-2776-8995"]},"institutions":[{"id":"https://openalex.org/I112281704","display_name":"Research Council of Finland","ror":"https://ror.org/05k73zm37","country_code":"FI","type":"government","lineage":["https://openalex.org/I112281704"]},{"id":"https://openalex.org/I9927081","display_name":"Aalto University","ror":"https://ror.org/020hwjq30","country_code":"FI","type":"education","lineage":["https://openalex.org/I9927081"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Adam L. Harmat","raw_affiliation_strings":["Department of Chemistry and Materials Science, Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland; Academy of Finland Center of Excellence in Life-Inspired Hybrid Materials (LIBER), Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Materials Science, Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland; Academy of Finland Center of Excellence in Life-Inspired Hybrid Materials (LIBER), Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland","institution_ids":["https://openalex.org/I112281704","https://openalex.org/I9927081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043055491","display_name":"Nea B. M\u00f6tt\u00f6nen","orcid":"https://orcid.org/0009-0005-3299-0058","observed_orcids":["https://orcid.org/0009-0005-3299-0058"]},"institutions":[{"id":"https://openalex.org/I112281704","display_name":"Research Council of Finland","ror":"https://ror.org/05k73zm37","country_code":"FI","type":"government","lineage":["https://openalex.org/I112281704"]},{"id":"https://openalex.org/I9927081","display_name":"Aalto University","ror":"https://ror.org/020hwjq30","country_code":"FI","type":"education","lineage":["https://openalex.org/I9927081"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Nea B. M\u00f6tt\u00f6nen","raw_affiliation_strings":["Department of Bioproducts and Biosystems, Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland; Academy of Finland Center of Excellence in Life-Inspired Hybrid Materials (LIBER), Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioproducts and Biosystems, Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland; Academy of Finland Center of Excellence in Life-Inspired Hybrid Materials (LIBER), Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland","institution_ids":["https://openalex.org/I112281704","https://openalex.org/I9927081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087459285","display_name":"Alberto Scacchi","orcid":"https://orcid.org/0000-0003-4606-5400","observed_orcids":["https://orcid.org/0000-0003-4606-5400"]},"institutions":[{"id":"https://openalex.org/I112281704","display_name":"Research Council of Finland","ror":"https://ror.org/05k73zm37","country_code":"FI","type":"government","lineage":["https://openalex.org/I112281704"]},{"id":"https://openalex.org/I155660961","display_name":"University of Turku","ror":"https://ror.org/05vghhr25","country_code":"FI","type":"education","lineage":["https://openalex.org/I155660961"]},{"id":"https://openalex.org/I9927081","display_name":"Aalto University","ror":"https://ror.org/020hwjq30","country_code":"FI","type":"education","lineage":["https://openalex.org/I9927081"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Alberto Scacchi","raw_affiliation_strings":["Department of Bioproducts and Biosystems, Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland; Academy of Finland Center of Excellence in Life-Inspired Hybrid Materials (LIBER), Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland; Department of Mechanical and Materials Engineering, University of Turku, Vesilinnantie 5, FI-20014, Turku, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioproducts and Biosystems, Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland; Academy of Finland Center of Excellence in Life-Inspired Hybrid Materials (LIBER), Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland; Department of Mechanical and Materials Engineering, University of Turku, Vesilinnantie 5, FI-20014, Turku, Finland","institution_ids":["https://openalex.org/I112281704","https://openalex.org/I155660961","https://openalex.org/I9927081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085039475","display_name":"Markus B. Linder","orcid":"https://orcid.org/0000-0002-7271-6441","observed_orcids":["https://orcid.org/0000-0002-7271-6441"]},"institutions":[{"id":"https://openalex.org/I112281704","display_name":"Research Council of Finland","ror":"https://ror.org/05k73zm37","country_code":"FI","type":"government","lineage":["https://openalex.org/I112281704"]},{"id":"https://openalex.org/I9927081","display_name":"Aalto University","ror":"https://ror.org/020hwjq30","country_code":"FI","type":"education","lineage":["https://openalex.org/I9927081"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Markus B. Linder","raw_affiliation_strings":["Department of Bioproducts and Biosystems, Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland; Academy of Finland Center of Excellence in Life-Inspired Hybrid Materials (LIBER), Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bioproducts and Biosystems, Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland; Academy of Finland Center of Excellence in Life-Inspired Hybrid Materials (LIBER), Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland","institution_ids":["https://openalex.org/I112281704","https://openalex.org/I9927081"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047081153","display_name":"Maria Sammalkorpi","orcid":"https://orcid.org/0000-0002-9248-430X","observed_orcids":["https://orcid.org/0000-0002-9248-430X"]},"institutions":[{"id":"https://openalex.org/I9927081","display_name":"Aalto University","ror":"https://ror.org/020hwjq30","country_code":"FI","type":"education","lineage":["https://openalex.org/I9927081"]}],"countries":["FI"],"is_corresponding":true,"raw_author_name":"Maria Sammalkorpi","raw_affiliation_strings":["Department of Chemistry and Materials Science, Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland; Academy of Finland Center of Excellence in Life-Inspired Hybrid Materials (LIBER), Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland. Electronic address: maria.sammalkorpi@aalto.fi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Materials Science, Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland; Academy of Finland Center of Excellence in Life-Inspired Hybrid Materials (LIBER), Aalto University, P.O. Box 16100, FI-00076, Aalto, Finland. Electronic address: maria.sammalkorpi@aalto.fi","institution_ids":["https://openalex.org/I9927081"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5047081153"],"corresponding_institution_ids":["https://openalex.org/I9927081"],"apc_list":{"value":4390,"currency":"USD","value_usd":4390},"apc_paid":{"value":4390,"currency":"USD","value_usd":4390},"fwci":0.1753,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.25865553,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"329","issue":"Pt 1","first_page":"147712","last_page":"147712"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11966","display_name":"Silk-based biomaterials and applications","score":0.8769999742507935,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11966","display_name":"Silk-based biomaterials and applications","score":0.8769999742507935,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11419","display_name":"Supramolecular Self-Assembly in Materials","score":0.11900000274181366,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/spidroin","display_name":"spidroin","score":0.8899999856948853},{"id":"https://openalex.org/keywords/protein-self-assembly","display_name":"protein self-assembly","score":0.8500000238418579},{"id":"https://openalex.org/keywords/thermal-gelation","display_name":"heat-induced gelation","score":0.8650000095367432},{"id":"https://openalex.org/keywords/intrinsically-disordered-regions","display_name":"intrinsically disordered regions","score":0.8190000057220459},{"id":"https://openalex.org/keywords/glycine-rich-region","display_name":"glycine-rich region","score":0.765999972820282},{"id":"https://openalex.org/keywords/hydrophobic-interactions","display_name":"hydrophobic interactions","score":0.8840000033378601},{"id":"https://openalex.org/keywords/protein-dimerization","display_name":"protein dimerization","score":0.6959999799728394},{"id":"https://openalex.org/keywords/percolation","display_name":"percolation","score":0.6740000247955322},{"id":"https://openalex.org/keywords/protein-gels","display_name":"protein gels","score":0.5699999928474426}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6951000094413757},{"id":"https://openalex.org/C159467904","wikidata":"https://www.wikidata.org/wiki/Q2001702","display_name":"Chemical physics","level":1,"score":0.6065000295639038},{"id":"https://openalex.org/C44280652","wikidata":"https://www.wikidata.org/wiki/Q104837","display_name":"Phase (matter)","level":2,"score":0.5663999915122986},{"id":"https://openalex.org/C2780457167","wikidata":"https://www.wikidata.org/wiki/Q17156484","display_name":"Percolation (cognitive psychology)","level":2,"score":0.5358999967575073},{"id":"https://openalex.org/C149288129","wikidata":"https://www.wikidata.org/wiki/Q185357","display_name":"Phase transition","level":2,"score":0.5228000283241272},{"id":"https://openalex.org/C106301342","wikidata":"https://www.wikidata.org/wiki/Q4117933","display_name":"Entropy (arrow of time)","level":2,"score":0.44859999418258667},{"id":"https://openalex.org/C160892712","wikidata":"https://www.wikidata.org/wiki/Q901559","display_name":"Fourier transform infrared spectroscopy","level":2,"score":0.44839999079704285},{"id":"https://openalex.org/C59593255","wikidata":"https://www.wikidata.org/wiki/Q901663","display_name":"Molecular dynamics","level":2,"score":0.44760000705718994},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.3939000070095062},{"id":"https://openalex.org/C204328495","wikidata":"https://www.wikidata.org/wiki/Q847556","display_name":"Protein folding","level":2,"score":0.39329999685287476},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.3635999858379364},{"id":"https://openalex.org/C2779856020","wikidata":"https://www.wikidata.org/wiki/Q218642","display_name":"Alanine","level":3,"score":0.36059999465942383},{"id":"https://openalex.org/C148898269","wikidata":"https://www.wikidata.org/wiki/Q1108792","display_name":"Kinetics","level":2,"score":0.3603000044822693},{"id":"https://openalex.org/C204530211","wikidata":"https://www.wikidata.org/wiki/Q752823","display_name":"Thermal","level":2,"score":0.3521000146865845},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3490999937057495},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.3125999867916107},{"id":"https://openalex.org/C26856880","wikidata":"https://www.wikidata.org/wiki/Q910150","display_name":"Self-assembly","level":2,"score":0.3089999854564667},{"id":"https://openalex.org/C11804247","wikidata":"https://www.wikidata.org/wiki/Q896177","display_name":"Protein\u2013protein interaction","level":2,"score":0.3061000108718872},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3010999858379364},{"id":"https://openalex.org/C2729557","wikidata":"https://www.wikidata.org/wiki/Q7167170","display_name":"Percolation threshold","level":3,"score":0.2904999852180481},{"id":"https://openalex.org/C18762648","wikidata":"https://www.wikidata.org/wiki/Q42213","display_name":"Work (physics)","level":2,"score":0.28459998965263367},{"id":"https://openalex.org/C124589349","wikidata":"https://www.wikidata.org/wiki/Q3726376","display_name":"Configuration entropy","level":2,"score":0.28200000524520874},{"id":"https://openalex.org/C136238340","wikidata":"https://www.wikidata.org/wiki/Q7251455","display_name":"Protein aggregation","level":2,"score":0.2799000144004822},{"id":"https://openalex.org/C62614982","wikidata":"https://www.wikidata.org/wiki/Q904984","display_name":"Protein secondary structure","level":2,"score":0.27730000019073486},{"id":"https://openalex.org/C39353612","wikidata":"https://www.wikidata.org/wiki/Q5283759","display_name":"Atmospheric temperature range","level":2,"score":0.26260000467300415},{"id":"https://openalex.org/C5637370","wikidata":"https://www.wikidata.org/wiki/Q402478","display_name":"Thermal fluctuations","level":2,"score":0.2513999938964844}],"mesh":[{"descriptor_ui":"D005349","descriptor_name":"Fibroins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005349","descriptor_name":"Fibroins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D012996","descriptor_name":"Solutions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013696","descriptor_name":"Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015202","descriptor_name":"Protein Engineering","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017433","descriptor_name":"Protein Structure, Secondary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044367","descriptor_name":"Phase Transition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056004","descriptor_name":"Molecular Dynamics Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057927","descriptor_name":"Hydrophobic and Hydrophilic Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1016/j.ijbiomac.2025.147712","doi":"https://doi.org/10.1016/j.ijbiomac.2025.147712","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ijbiomac.2025.147712","pdf_url":null,"source":{"id":"https://openalex.org/S83853393","display_name":"International Journal of Biological Macromolecules","issn_l":"0141-8130","issn":["0141-8130","1879-0003"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Biological Macromolecules","raw_type":"journal-article"},{"id":"pmid:40967530","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40967530","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of biological macromolecules","raw_type":"Journal Article"},{"id":"pmh:oai:aaltodoc.aalto.fi:123456789/140506","doi":null,"is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ijbiomac.2025.147712","pdf_url":null,"source":{"id":"https://openalex.org/S4306401662","display_name":"Aaltodoc (Aalto University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I9927081","host_organization_name":"Aalto University","host_organization_lineage":["https://openalex.org/I9927081"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:utupub.fi:11111/53989","doi":null,"is_oa":true,"landing_page_url":"https://www.utupub.fi/handle/11111/53989","pdf_url":"https://www.utupub.fi/bitstreams/137c141e-6643-4f8c-b6d1-a8a7aca19ed4/download","source":{"id":"https://openalex.org/S4306402470","display_name":"UTUPub (University of Turku)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I155660961","host_organization_name":"University of Turku","host_organization_lineage":["https://openalex.org/I155660961"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"https://www.utupub.fi/handle/10024/195919","raw_type":null},{"id":"pmh:oai:www.utupub.fi:10024/195919","doi":null,"is_oa":true,"landing_page_url":"https://www.utupub.fi/handle/10024/195919","pdf_url":"https://www.utupub.fi/bitstream/10024/195919/1/1-s2.0-S0141813025082698-main.pdf","source":{"id":"https://openalex.org/S4306402470","display_name":"UTUPub (University of Turku)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I155660961","host_organization_name":"University of Turku","host_organization_lineage":["https://openalex.org/I155660961"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"pmh:oai:publica.fraunhofer.de:publica/497168","doi":null,"is_oa":false,"landing_page_url":"https://publica.fraunhofer.de/handle/publica/497168","pdf_url":null,"source":{"id":"https://openalex.org/S4306400318","display_name":"Fraunhofer-Publica (Fraunhofer-Gesellschaft)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4923324","host_organization_name":"Fraunhofer-Gesellschaft","host_organization_lineage":["https://openalex.org/I4923324"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"}],"best_oa_location":{"id":"doi:10.1016/j.ijbiomac.2025.147712","doi":"https://doi.org/10.1016/j.ijbiomac.2025.147712","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ijbiomac.2025.147712","pdf_url":null,"source":{"id":"https://openalex.org/S83853393","display_name":"International Journal of Biological Macromolecules","issn_l":"0141-8130","issn":["0141-8130","1879-0003"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Biological Macromolecules","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1581671271","display_name":"Center of Excellence in Life-Inspired Hybrid Materials","funder_award_id":"346111","funder_id":"https://openalex.org/F4320321108","funder_display_name":"Academy of Finland"},{"id":"https://openalex.org/G2680997403","display_name":null,"funder_award_id":"352955","funder_id":"https://openalex.org/F4320321394","funder_display_name":"Aalto-Yliopisto"},{"id":"https://openalex.org/G3603259962","display_name":null,"funder_award_id":"2022-2029","funder_id":"https://openalex.org/F4320321108","funder_display_name":"Academy of Finland"},{"id":"https://openalex.org/G4562911668","display_name":null,"funder_award_id":"NNF22OC0074060","funder_id":"https://openalex.org/F4320322436","funder_display_name":"Novo Nordisk"},{"id":"https://openalex.org/G4598041425","display_name":null,"funder_award_id":"NNF22OC0074060","funder_id":"https://openalex.org/F4320325957","funder_display_name":"Novo Nordisk Fonden"},{"id":"https://openalex.org/G4632460807","display_name":null,"funder_award_id":"NNF20OC0061306","funder_id":"https://openalex.org/F4320325957","funder_display_name":"Novo Nordisk Fonden"},{"id":"https://openalex.org/G4669141798","display_name":"Center of Excellence in Life-Inspired Hybrid Materials","funder_award_id":"346105","funder_id":"https://openalex.org/F4320321108","funder_display_name":"Academy of Finland"},{"id":"https://openalex.org/G5089815398","display_name":null,"funder_award_id":"NNF22OC0079084","funder_id":"https://openalex.org/F4320325957","funder_display_name":"Novo Nordisk Fonden"},{"id":"https://openalex.org/G6788256735","display_name":null,"funder_award_id":"NNF20OC0061306","funder_id":"https://openalex.org/F4320322436","funder_display_name":"Novo Nordisk"},{"id":"https://openalex.org/G7197725846","display_name":null,"funder_award_id":"352955","funder_id":"https://openalex.org/F4320321108","funder_display_name":"Academy of Finland"},{"id":"https://openalex.org/G8525363613","display_name":"Water-driven transitions in coacervates (WATRAN)","funder_award_id":"359180","funder_id":"https://openalex.org/F4320321108","funder_display_name":"Academy of Finland"}],"funders":[{"id":"https://openalex.org/F1100377486","display_name":"European High Performance Computing Joint Undertaking","ror":"https://ror.org/04dvh0v63"},{"id":"https://openalex.org/F4320321108","display_name":"Academy of Finland","ror":"https://ror.org/05k73zm37"},{"id":"https://openalex.org/F4320321394","display_name":"Aalto-Yliopisto","ror":"https://ror.org/020hwjq30"},{"id":"https://openalex.org/F4320322436","display_name":"Novo Nordisk","ror":"https://ror.org/0435rc536"},{"id":"https://openalex.org/F4320322725","display_name":"China Scholarship Council","ror":"https://ror.org/04atp4p48"},{"id":"https://openalex.org/F4320325957","display_name":"Novo Nordisk Fonden","ror":"https://ror.org/04txyc737"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4414224699.pdf","grobid_xml":"https://content.openalex.org/works/W4414224699.grobid-xml"},"referenced_works_count":134,"referenced_works":["https://openalex.org/W225968618","https://openalex.org/W1031578623","https://openalex.org/W1538202910","https://openalex.org/W1933753908","https://openalex.org/W1964808992","https://openalex.org/W1965904253","https://openalex.org/W1983229094","https://openalex.org/W1987506711","https://openalex.org/W1991794210","https://openalex.org/W1998816055","https://openalex.org/W2000456051","https://openalex.org/W2005508232","https://openalex.org/W2013411504","https://openalex.org/W2014455368","https://openalex.org/W2014550271","https://openalex.org/W2017196167","https://openalex.org/W2017748547","https://openalex.org/W2018182349","https://openalex.org/W2026787105","https://openalex.org/W2029667189","https://openalex.org/W2031344083","https://openalex.org/W2035687084","https://openalex.org/W2036712659","https://openalex.org/W2041278780","https://openalex.org/W2044821164","https://openalex.org/W2047474238","https://openalex.org/W2049121146","https://openalex.org/W2059013803","https://openalex.org/W2063237839","https://openalex.org/W2067174909","https://openalex.org/W2068465654","https://openalex.org/W2071600461","https://openalex.org/W2071794983","https://openalex.org/W2081693079","https://openalex.org/W2087118158","https://openalex.org/W2087457566","https://openalex.org/W2088373632","https://openalex.org/W2092597250","https://openalex.org/W2104571730","https://openalex.org/W2130307458","https://openalex.org/W2136141445","https://openalex.org/W2140166820","https://openalex.org/W2141150276","https://openalex.org/W2146232677","https://openalex.org/W2146585145","https://openalex.org/W2147791888","https://openalex.org/W2155800892","https://openalex.org/W2155916246","https://openalex.org/W2168300796","https://openalex.org/W2170711116","https://openalex.org/W2207525560","https://openalex.org/W2234602429","https://openalex.org/W2252354019","https://openalex.org/W2258157621","https://openalex.org/W2283125016","https://openalex.org/W2292088939","https://openalex.org/W2313394576","https://openalex.org/W2327000477","https://openalex.org/W2331858061","https://openalex.org/W2416486977","https://openalex.org/W2426613120","https://openalex.org/W2510475640","https://openalex.org/W2579105790","https://openalex.org/W2593862218","https://openalex.org/W2595614671","https://openalex.org/W2611048578","https://openalex.org/W2611416155","https://openalex.org/W2740507605","https://openalex.org/W2763273892","https://openalex.org/W2792129356","https://openalex.org/W2792225769","https://openalex.org/W2800697076","https://openalex.org/W2802429563","https://openalex.org/W2809941613","https://openalex.org/W2810350665","https://openalex.org/W2884549392","https://openalex.org/W2891753890","https://openalex.org/W2897343320","https://openalex.org/W2921063431","https://openalex.org/W2921365922","https://openalex.org/W2948530956","https://openalex.org/W2951283121","https://openalex.org/W2981272131","https://openalex.org/W2992138441","https://openalex.org/W3004986270","https://openalex.org/W3006198804","https://openalex.org/W3026726192","https://openalex.org/W3027267713","https://openalex.org/W3029364940","https://openalex.org/W3035871125","https://openalex.org/W3082327511","https://openalex.org/W3086392376","https://openalex.org/W3121039671","https://openalex.org/W3159328265","https://openalex.org/W3168329048","https://openalex.org/W3179905103","https://openalex.org/W3201009248","https://openalex.org/W4200169022","https://openalex.org/W4206536854","https://openalex.org/W4211193688","https://openalex.org/W4247272913","https://openalex.org/W4281688348","https://openalex.org/W4284707449","https://openalex.org/W4284973443","https://openalex.org/W4291551593","https://openalex.org/W4296536087","https://openalex.org/W4296592000","https://openalex.org/W4317615544","https://openalex.org/W4320895099","https://openalex.org/W4323322124","https://openalex.org/W4323350303","https://openalex.org/W4366495670","https://openalex.org/W4366605540","https://openalex.org/W4388626562","https://openalex.org/W4388692992","https://openalex.org/W4389132340","https://openalex.org/W4389705971","https://openalex.org/W4390743944","https://openalex.org/W4390786901","https://openalex.org/W4392360160","https://openalex.org/W4394566007","https://openalex.org/W4397003391","https://openalex.org/W4397004087","https://openalex.org/W4400485270","https://openalex.org/W4401412935","https://openalex.org/W4402564785","https://openalex.org/W4402575285","https://openalex.org/W4402898532","https://openalex.org/W4403098186","https://openalex.org/W4404254427","https://openalex.org/W4404285194","https://openalex.org/W4404494971","https://openalex.org/W4408788310","https://openalex.org/W4412654454"],"related_works":["https://openalex.org/W4284707449","https://openalex.org/W2031344083","https://openalex.org/W4402575285","https://openalex.org/W2325824932","https://openalex.org/W4378348197","https://openalex.org/W1968199817","https://openalex.org/W2801522763","https://openalex.org/W4412654454","https://openalex.org/W2982568903","https://openalex.org/W2809941613"],"abstract_inverted_index":{"Here,":[0],"we":[1,34,108,182],"explore":[2],"the":[3,8,36,59,84,89,92,97,101,126,136,140,143,155,161,167,171,175,191,199,208],"molecular":[4,22,192],"level":[5,193],"origins":[6],"of":[7,17,40,86,91,132,154,160,170,177,198],"curious":[9],"temperature":[10,66],"and":[11,26,52,70,96,115,129,195,203,211],"time":[12,184],"dependent":[13],"assembly":[14,37,60,205],"phase":[15,38,61,79],"response":[16,39,62],"silk-like":[18,200],"protein":[19,44,137,201],"materials.":[20],"Combining":[21],"dynamics":[23],"simulations,":[24],"CD":[25],"FTIR":[27],"spectroscopy,":[28],"as":[29,31,185],"well":[30],"optical":[32],"microscopy,":[33],"examine":[35],"model":[41],"engineered":[42],"tri-block":[43],"constructs":[45],"with":[46,148],"a":[47,64,186],"middle":[48,156],"intrinsically":[49],"disordered":[50],"region":[51],"folded":[53],"terminal":[54,172],"domains.":[55,173],"We":[56],"show":[57],"that,":[58],"over":[63],"broad":[65],"range":[67],"between":[68,100,125],"20":[69],"80":[71],"\u00b0C":[72],"arises":[73],"from":[74,190],"strong":[75],"interprotein":[76],"interactions.":[77],"The":[78],"transitions":[80,153],"are":[81],"governed":[82],"by":[83],"interplay":[85],"changes":[87],"in":[88,104],"entropy":[90],"flexible":[93],"glycine-rich":[94],"regions":[95,128],"hydrophobic":[98],"interactions":[99,124,169],"\u03b1-helices":[102],"rich":[103],"alanine":[105],"(Ala).":[106],"Furthermore,":[107],"observe":[109],"irreversible":[110],"gelation":[111,121],"at":[112],"high":[113],"temperatures":[114],"during":[116],"aging":[117],"(time-induced":[118],"gelation).":[119],"Thermal":[120],"rises":[122],"via":[123,158],"Ala-rich":[127],"subsequent":[130],"formation":[131,210],"\u03b2-sheets":[133],"that":[134,181],"crosslink":[135],"network.":[138],"On":[139],"other":[141],"hand,":[142],"time-induced":[144],"gel":[145,209],"is":[146,164,180],"formed":[147],"no":[149],"notable":[150],"secondary":[151],"structure":[152],"block":[157],"percolation":[159],"protein,":[162],"which":[163],"sensitive":[165],"to":[166],"dimerizing":[168],"Overall,":[174],"significance":[176],"this":[178],"work":[179],"identify":[183],"separate":[187],"design":[188],"variable":[189],"characteristics":[194],"solution":[196],"conditions":[197],"gels,":[202],"extract":[204],"guidelines":[206],"for":[207],"its":[212],"characteristics.":[213]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2025-10-10T00:00:00"}