{"id":"https://openalex.org/W4414166991","doi":"https://doi.org/10.1016/j.anaerobe.2025.102996","title":"Zebrafish as an in vivo model to study the pathogenicity of Clostridioides difficile clinical strains","display_name":"Zebrafish as an in vivo model to study the pathogenicity of Clostridioides difficile clinical strains","publication_year":2025,"publication_date":"2025-09-12","ids":{"openalex":"https://openalex.org/W4414166991","doi":"https://doi.org/10.1016/j.anaerobe.2025.102996","pmid":"https://pubmed.ncbi.nlm.nih.gov/40947092"},"language":"en","primary_location":{"id":"doi:10.1016/j.anaerobe.2025.102996","doi":"https://doi.org/10.1016/j.anaerobe.2025.102996","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.anaerobe.2025.102996","pdf_url":null,"source":{"id":"https://openalex.org/S187465954","display_name":"Anaerobe","issn_l":"1075-9964","issn":["1075-9964","1095-8274"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anaerobe","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076700892","display_name":"Camila Rizek","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Camila Fonseca Rizek","raw_affiliation_strings":["Laborat\u00f3rio de Investiga\u00e7\u00e3o M\u00e9dica 49, Departamento de Infectologia e Medicina Tropical da Faculdade de Medicina da Universidade de S\u00e3o Paulo, Av. Dr. Eneas de Carvalho Aguiar, 470, S\u00e3o Paulo, Brazil. Electronic address: camilarizek@gmail.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Investiga\u00e7\u00e3o M\u00e9dica 49, Departamento de Infectologia e Medicina Tropical da Faculdade de Medicina da Universidade de S\u00e3o Paulo, Av. Dr. Eneas de Carvalho Aguiar, 470, S\u00e3o Paulo, Brazil. Electronic address: camilarizek@gmail.com","institution_ids":["https://openalex.org/I17974374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080246268","display_name":"Marina Farrel C\u00f4rtes","orcid":"https://orcid.org/0000-0003-1925-4855","observed_orcids":["https://orcid.org/0000-0003-1925-4855"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Marina Farrel C\u00f4rtes","raw_affiliation_strings":["Laborat\u00f3rio de Investiga\u00e7\u00e3o M\u00e9dica 49, Departamento de Infectologia e Medicina Tropical da Faculdade de Medicina da Universidade de S\u00e3o Paulo, Av. Dr. Eneas de Carvalho Aguiar, 470, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Investiga\u00e7\u00e3o M\u00e9dica 49, Departamento de Infectologia e Medicina Tropical da Faculdade de Medicina da Universidade de S\u00e3o Paulo, Av. Dr. Eneas de Carvalho Aguiar, 470, S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I17974374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072496292","display_name":"Bianca Helena Ventura Fernandes","orcid":"https://orcid.org/0000-0002-2213-4355","observed_orcids":["https://orcid.org/0000-0002-2213-4355"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Bianca Helena Ventura Fernandes","raw_affiliation_strings":["N\u00facleo Multiusu\u00e1rio Zebrafish, Divis\u00e3o T\u00e9cnica de Apoio ao Ensino e Pesquisa, Faculdade de Medicina da Universidade de S\u00e3o Paulo, Av. Dr. Eneas de Carvalho Aguiar, 470, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"N\u00facleo Multiusu\u00e1rio Zebrafish, Divis\u00e3o T\u00e9cnica de Apoio ao Ensino e Pesquisa, Faculdade de Medicina da Universidade de S\u00e3o Paulo, Av. Dr. Eneas de Carvalho Aguiar, 470, S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I17974374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003824515","display_name":"S\u00edlvia Figueiredo Costa","orcid":"https://orcid.org/0000-0003-1087-752X","observed_orcids":["https://orcid.org/0000-0003-1087-752X"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4210145268","display_name":"Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo","ror":"https://ror.org/03se9eg94","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210145268"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Silvia Figueiredo Costa","raw_affiliation_strings":["Laborat\u00f3rio de Investiga\u00e7\u00e3o M\u00e9dica 49, Departamento de Infectologia e Medicina Tropical da Faculdade de Medicina da Universidade de S\u00e3o Paulo, Av. Dr. Eneas de Carvalho Aguiar, 470, S\u00e3o Paulo, Brazil; Hospital das Cl\u00ednicas, Faculdade de Medicina, Universidade de S\u00e3o Paulo, Av. Dr. Eneas de Carvalho Aguiar, 255, S\u00e3o Paulo, Brazil; Centres for Antimicrobial Optimisation Network (CAMO-Net) Brazil, Faculty of Medicine, University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Investiga\u00e7\u00e3o M\u00e9dica 49, Departamento de Infectologia e Medicina Tropical da Faculdade de Medicina da Universidade de S\u00e3o Paulo, Av. Dr. Eneas de Carvalho Aguiar, 470, S\u00e3o Paulo, Brazil; Hospital das Cl\u00ednicas, Faculdade de Medicina, Universidade de S\u00e3o Paulo, Av. Dr. Eneas de Carvalho Aguiar, 255, S\u00e3o Paulo, Brazil; Centres for Antimicrobial Optimisation Network (CAMO-Net) Brazil, Faculty of Medicine, University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I17974374","https://openalex.org/I4210145268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072325969","display_name":"Evelyne Santana Gir\u00e3o","orcid":"https://orcid.org/0000-0003-3059-5490","observed_orcids":["https://orcid.org/0000-0003-3059-5490"]},"institutions":[{"id":"https://openalex.org/I243754102","display_name":"Universidade Federal do Cear\u00e1","ror":"https://ror.org/03srtnf24","country_code":"BR","type":"education","lineage":["https://openalex.org/I243754102"]},{"id":"https://openalex.org/I4210106783","display_name":"Hospital Universit\u00e1rio Walter Cant\u00eddio","ror":"https://ror.org/01d9cfw89","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210106783"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Evelyne Santana Gir\u00e3o","raw_affiliation_strings":["Hospital Universit\u00e1rio Walter Cant\u00eddio, Universidade Federal do Cear\u00e1, R. Pastor Samuel Munguba, 1290, Cear\u00e1, Fortaleza, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Universit\u00e1rio Walter Cant\u00eddio, Universidade Federal do Cear\u00e1, R. Pastor Samuel Munguba, 1290, Cear\u00e1, Fortaleza, Brazil","institution_ids":["https://openalex.org/I243754102","https://openalex.org/I4210106783"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023072392","display_name":"Roberta Cristina Ruedas Martins","orcid":"https://orcid.org/0000-0003-0775-7527","observed_orcids":["https://orcid.org/0000-0003-0775-7527"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Roberta Cristina Martins","raw_affiliation_strings":["Laborat\u00f3rio de Investiga\u00e7\u00e3o M\u00e9dica 49, Departamento de Infectologia e Medicina Tropical da Faculdade de Medicina da Universidade de S\u00e3o Paulo, Av. Dr. Eneas de Carvalho Aguiar, 470, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Investiga\u00e7\u00e3o M\u00e9dica 49, Departamento de Infectologia e Medicina Tropical da Faculdade de Medicina da Universidade de S\u00e3o Paulo, Av. Dr. Eneas de Carvalho Aguiar, 470, S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I17974374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005405680","display_name":"S\u00e2nia Alves dos Santos","orcid":"https://orcid.org/0000-0002-1325-6895","observed_orcids":["https://orcid.org/0000-0002-1325-6895"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"S\u00e2nia Alves dos Santos","raw_affiliation_strings":["Laborat\u00f3rio de Investiga\u00e7\u00e3o M\u00e9dica 49, Departamento de Infectologia e Medicina Tropical da Faculdade de Medicina da Universidade de S\u00e3o Paulo, Av. Dr. Eneas de Carvalho Aguiar, 470, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Investiga\u00e7\u00e3o M\u00e9dica 49, Departamento de Infectologia e Medicina Tropical da Faculdade de Medicina da Universidade de S\u00e3o Paulo, Av. Dr. Eneas de Carvalho Aguiar, 470, S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I17974374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004308031","display_name":"Bruno de Melo Tavares","orcid":"https://orcid.org/0000-0002-8628-968X","observed_orcids":["https://orcid.org/0000-0002-8628-968X"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I4210145268","display_name":"Hospital das Cl\u00ednicas da Faculdade de Medicina da Universidade de S\u00e3o Paulo","ror":"https://ror.org/03se9eg94","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210145268"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Bruno de Melo Tavares","raw_affiliation_strings":["Hospital das Cl\u00ednicas, Faculdade de Medicina, Universidade de S\u00e3o Paulo, Av. Dr. Eneas de Carvalho Aguiar, 255, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital das Cl\u00ednicas, Faculdade de Medicina, Universidade de S\u00e3o Paulo, Av. Dr. Eneas de Carvalho Aguiar, 255, S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I17974374","https://openalex.org/I4210145268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000888722","display_name":"Luciani R. S. Carvalho","orcid":"https://orcid.org/0000-0002-7313-2130","observed_orcids":["https://orcid.org/0000-0002-7313-2130"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Luciani Silveira de Carvalho","raw_affiliation_strings":["N\u00facleo Multiusu\u00e1rio Zebrafish, Divis\u00e3o T\u00e9cnica de Apoio ao Ensino e Pesquisa, Faculdade de Medicina da Universidade de S\u00e3o Paulo, Av. Dr. Eneas de Carvalho Aguiar, 470, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"N\u00facleo Multiusu\u00e1rio Zebrafish, Divis\u00e3o T\u00e9cnica de Apoio ao Ensino e Pesquisa, Faculdade de Medicina da Universidade de S\u00e3o Paulo, Av. Dr. Eneas de Carvalho Aguiar, 470, S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I17974374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051011956","display_name":"Cec\u00edlia Leite Costa","orcid":"https://orcid.org/0000-0003-0963-2904","observed_orcids":["https://orcid.org/0000-0003-0963-2904"]},"institutions":[{"id":"https://openalex.org/I243754102","display_name":"Universidade Federal do Cear\u00e1","ror":"https://ror.org/03srtnf24","country_code":"BR","type":"education","lineage":["https://openalex.org/I243754102"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Cecilia Leite Costa","raw_affiliation_strings":["Departamento de Morfologia, Universidade Federal do Cear\u00e1, R. Delmiro de Farias, Cear\u00e1, Fortaleza, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Morfologia, Universidade Federal do Cear\u00e1, R. Delmiro de Farias, Cear\u00e1, Fortaleza, Brazil","institution_ids":["https://openalex.org/I243754102"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078215481","display_name":"Daniely Viana Costa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I243754102","display_name":"Universidade Federal do Cear\u00e1","ror":"https://ror.org/03srtnf24","country_code":"BR","type":"education","lineage":["https://openalex.org/I243754102"]},{"id":"https://openalex.org/I4210106783","display_name":"Hospital Universit\u00e1rio Walter Cant\u00eddio","ror":"https://ror.org/01d9cfw89","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210106783"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Daniely Viana Costa","raw_affiliation_strings":["Hospital Universit\u00e1rio Walter Cant\u00eddio, Universidade Federal do Cear\u00e1, R. Pastor Samuel Munguba, 1290, Cear\u00e1, Fortaleza, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Universit\u00e1rio Walter Cant\u00eddio, Universidade Federal do Cear\u00e1, R. Pastor Samuel Munguba, 1290, Cear\u00e1, Fortaleza, Brazil","institution_ids":["https://openalex.org/I243754102","https://openalex.org/I4210106783"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016005207","display_name":"Geovania Maciel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I243754102","display_name":"Universidade Federal do Cear\u00e1","ror":"https://ror.org/03srtnf24","country_code":"BR","type":"education","lineage":["https://openalex.org/I243754102"]},{"id":"https://openalex.org/I4210106783","display_name":"Hospital Universit\u00e1rio Walter Cant\u00eddio","ror":"https://ror.org/01d9cfw89","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210106783"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Geovania Maciel","raw_affiliation_strings":["Hospital Universit\u00e1rio Walter Cant\u00eddio, Universidade Federal do Cear\u00e1, R. Pastor Samuel Munguba, 1290, Cear\u00e1, Fortaleza, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Universit\u00e1rio Walter Cant\u00eddio, Universidade Federal do Cear\u00e1, R. Pastor Samuel Munguba, 1290, Cear\u00e1, Fortaleza, Brazil","institution_ids":["https://openalex.org/I243754102","https://openalex.org/I4210106783"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086070985","display_name":"Gerly Anne de Castro Brito","orcid":"https://orcid.org/0000-0002-8214-4379","observed_orcids":["https://orcid.org/0000-0002-8214-4379"]},"institutions":[{"id":"https://openalex.org/I243754102","display_name":"Universidade Federal do Cear\u00e1","ror":"https://ror.org/03srtnf24","country_code":"BR","type":"education","lineage":["https://openalex.org/I243754102"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Gerly Anne de Castro Brito","raw_affiliation_strings":["Departamento de Morfologia, Universidade Federal do Cear\u00e1, R. Delmiro de Farias, Cear\u00e1, Fortaleza, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Morfologia, Universidade Federal do Cear\u00e1, R. Delmiro de Farias, Cear\u00e1, Fortaleza, Brazil","institution_ids":["https://openalex.org/I243754102"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086624368","display_name":"Lauro Vieira Perdig\u00e3o Neto","orcid":"https://orcid.org/0000-0002-7681-8090","observed_orcids":["https://orcid.org/0000-0002-7681-8090"]},"institutions":[{"id":"https://openalex.org/I17974374","display_name":"Universidade de S\u00e3o Paulo","ror":"https://ror.org/036rp1748","country_code":"BR","type":"education","lineage":["https://openalex.org/I17974374"]},{"id":"https://openalex.org/I243754102","display_name":"Universidade Federal do Cear\u00e1","ror":"https://ror.org/03srtnf24","country_code":"BR","type":"education","lineage":["https://openalex.org/I243754102"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Lauro Vieira Perdig\u00e3o Neto","raw_affiliation_strings":["Laborat\u00f3rio de Investiga\u00e7\u00e3o M\u00e9dica 49, Departamento de Infectologia e Medicina Tropical da Faculdade de Medicina da Universidade de S\u00e3o Paulo, Av. Dr. Eneas de Carvalho Aguiar, 470, S\u00e3o Paulo, Brazil; Departamento de Sa\u00fade Comunit\u00e1ria, Universidade Federal do Cear\u00e1, Cear\u00e1, Fortaleza, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laborat\u00f3rio de Investiga\u00e7\u00e3o M\u00e9dica 49, Departamento de Infectologia e Medicina Tropical da Faculdade de Medicina da Universidade de S\u00e3o Paulo, Av. Dr. Eneas de Carvalho Aguiar, 470, S\u00e3o Paulo, Brazil; Departamento de Sa\u00fade Comunit\u00e1ria, Universidade Federal do Cear\u00e1, Cear\u00e1, Fortaleza, Brazil","institution_ids":["https://openalex.org/I17974374","https://openalex.org/I243754102"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5076700892"],"corresponding_institution_ids":["https://openalex.org/I17974374"],"apc_list":{"value":3350,"currency":"USD","value_usd":3350},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"96","issue":null,"first_page":"102996","last_page":"102996"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11288","display_name":"Clostridium difficile and Clostridium perfringens research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11288","display_name":"Clostridium difficile and Clostridium perfringens research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11685","display_name":"Zebrafish Biomedical Research Applications","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10943","display_name":"Escherichia coli research studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/clostridioides-difficile","display_name":"Clostridium difficile","score":0.9959999918937683},{"id":"https://openalex.org/keywords/zebrafish-embryo-model","display_name":"zebrafish embryo model","score":0.9380000233650208},{"id":"https://openalex.org/keywords/bacterial-virulence","display_name":"bacterial virulence","score":0.7699999809265137},{"id":"https://openalex.org/keywords/cardiotoxicity","display_name":"cardiotoxicity","score":0.9049999713897705},{"id":"https://openalex.org/keywords/cardiac-edema","display_name":"cardiac edema","score":0.8939999938011169},{"id":"https://openalex.org/keywords/strain-specific-virulence","display_name":"strain-specific virulence","score":0.7319999933242798},{"id":"https://openalex.org/keywords/nosocomial-diarrhea","display_name":"nosocomial diarrhea","score":0.7450000047683716},{"id":"https://openalex.org/keywords/whole-genome-sequencing","display_name":"whole genome sequencing","score":0.5450000166893005},{"id":"https://openalex.org/keywords/animal-model-validation","display_name":"animal model validation","score":0.5230000019073486}],"concepts":[{"id":"https://openalex.org/C2776878037","wikidata":"https://www.wikidata.org/wiki/Q169444","display_name":"Zebrafish","level":3,"score":0.8838000297546387},{"id":"https://openalex.org/C2910067853","wikidata":"https://www.wikidata.org/wiki/Q27438828","display_name":"Clostridioides","level":2,"score":0.8256000280380249},{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.8187000155448914},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7940999865531921},{"id":"https://openalex.org/C64502627","wikidata":"https://www.wikidata.org/wiki/Q170065","display_name":"Pathogenicity","level":2,"score":0.7193999886512756},{"id":"https://openalex.org/C2776927270","wikidata":"https://www.wikidata.org/wiki/Q815962","display_name":"Colonization","level":2,"score":0.6597999930381775},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.6506999731063843},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5838000178337097},{"id":"https://openalex.org/C19843653","wikidata":"https://www.wikidata.org/wiki/Q213907","display_name":"Model organism","level":3,"score":0.4074000120162964},{"id":"https://openalex.org/C2778117688","wikidata":"https://www.wikidata.org/wiki/Q264024","display_name":"Animal model","level":2,"score":0.36649999022483826},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.3224000036716461},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.31859999895095825},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.3181000053882599},{"id":"https://openalex.org/C2988540567","wikidata":"https://www.wikidata.org/wiki/Q12070446","display_name":"Model system","level":2,"score":0.2953999936580658},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.2922999858856201},{"id":"https://openalex.org/C180223184","wikidata":"https://www.wikidata.org/wiki/Q4839986","display_name":"Bacterial genetics","level":4,"score":0.27709999680519104},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.27469998598098755},{"id":"https://openalex.org/C62130838","wikidata":"https://www.wikidata.org/wiki/Q5196163","display_name":"Pathogenicity island","level":4,"score":0.2667999863624573},{"id":"https://openalex.org/C9043230","wikidata":"https://www.wikidata.org/wiki/Q262657","display_name":"Microbial toxins","level":3,"score":0.25429999828338623},{"id":"https://openalex.org/C2909208804","wikidata":"https://www.wikidata.org/wiki/Q127282","display_name":"Fish <Actinopterygii>","level":2,"score":0.25270000100135803}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003015","descriptor_name":"Clostridium Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D003015","descriptor_name":"Clostridium Infections","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004625","descriptor_name":"Embryo, Nonmammalian","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014774","descriptor_name":"Virulence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015027","descriptor_name":"Zebrafish","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D016360","descriptor_name":"Clostridioides difficile","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D016360","descriptor_name":"Clostridioides difficile","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016360","descriptor_name":"Clostridioides difficile","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.anaerobe.2025.102996","doi":"https://doi.org/10.1016/j.anaerobe.2025.102996","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.anaerobe.2025.102996","pdf_url":null,"source":{"id":"https://openalex.org/S187465954","display_name":"Anaerobe","issn_l":"1075-9964","issn":["1075-9964","1095-8274"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anaerobe","raw_type":"journal-article"},{"id":"pmid:40947092","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40947092","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anaerobe","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W2029573145","https://openalex.org/W2122060112","https://openalex.org/W2170890477","https://openalex.org/W2430707886","https://openalex.org/W2549382215","https://openalex.org/W2799762643","https://openalex.org/W2805369985","https://openalex.org/W2911255357","https://openalex.org/W2969368291","https://openalex.org/W2997503984","https://openalex.org/W3032569678","https://openalex.org/W3093505592","https://openalex.org/W3109814636","https://openalex.org/W3139791082","https://openalex.org/W3164451222","https://openalex.org/W3195275742","https://openalex.org/W3200227464","https://openalex.org/W4213137979","https://openalex.org/W4224245636","https://openalex.org/W4308567762","https://openalex.org/W4311050670","https://openalex.org/W4313705015","https://openalex.org/W4388718519","https://openalex.org/W4399857161"],"related_works":["https://openalex.org/W2936842469","https://openalex.org/W7084495862","https://openalex.org/W2170890477","https://openalex.org/W3006605736","https://openalex.org/W1965629335","https://openalex.org/W4313705015","https://openalex.org/W7084575283","https://openalex.org/W2744035276","https://openalex.org/W2132207617","https://openalex.org/W2158896201"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2025-10-10T00:00:00"}