{"id":"https://openalex.org/W4414108317","doi":"https://doi.org/10.70780/medpeer.000qgov","title":"Care pathway of patients with lung cancer: Retrospective study of 100 patients managed at the national institute of oncology in Rabat","display_name":"Care pathway of patients with lung cancer: Retrospective study of 100 patients managed at the national institute of oncology in Rabat","publication_year":2025,"publication_date":"2025-01-01","ids":{"openalex":"https://openalex.org/W4414108317","doi":"https://doi.org/10.70780/medpeer.000qgov"},"language":"en","primary_location":{"id":"doi:10.70780/medpeer.000qgov","doi":"https://doi.org/10.70780/medpeer.000qgov","is_oa":true,"landing_page_url":"https://doi.org/10.70780/medpeer.000qgov","pdf_url":"http://www.medpeerpublishers.com/articles/120.pdf","source":{"id":"https://openalex.org/S5407048740","display_name":"MedPeer publisher","issn_l":"3066-2737","issn":["3066-2737"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"MedPeer publisher","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.medpeerpublishers.com/articles/120.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5099983143","display_name":"Rania Alem","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130352","display_name":"Centre Hospitalier Ibn Sina","ror":"https://ror.org/038zpvz53","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210130352"]},{"id":"https://openalex.org/I4210152075","display_name":"Institut National d'Oncologie","ror":"https://ror.org/0132nee26","country_code":"MA","type":"facility","lineage":["https://openalex.org/I4210152075"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Rania Alem","raw_affiliation_strings":["Departement of medical oncologie , National Institute of Oncology , CHU Ibn Sina University Hospital Center , Rabat , MAR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departement of medical oncologie , National Institute of Oncology , CHU Ibn Sina University Hospital Center , Rabat , MAR","institution_ids":["https://openalex.org/I4210130352","https://openalex.org/I4210152075"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107436966","display_name":"Loubna Omri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130352","display_name":"Centre Hospitalier Ibn Sina","ror":"https://ror.org/038zpvz53","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210130352"]},{"id":"https://openalex.org/I4210152075","display_name":"Institut National d'Oncologie","ror":"https://ror.org/0132nee26","country_code":"MA","type":"facility","lineage":["https://openalex.org/I4210152075"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Loubna Omri","raw_affiliation_strings":["Departement of medical oncologie , National Institute of Oncology , CHU Ibn Sina University Hospital Center , Rabat , MAR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departement of medical oncologie , National Institute of Oncology , CHU Ibn Sina University Hospital Center , Rabat , MAR","institution_ids":["https://openalex.org/I4210130352","https://openalex.org/I4210152075"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113782429","display_name":"Sihame Lkhoyaali","orcid":"https://orcid.org/0000-0003-3119-7654","observed_orcids":["https://orcid.org/0000-0003-3119-7654"]},"institutions":[{"id":"https://openalex.org/I4210130352","display_name":"Centre Hospitalier Ibn Sina","ror":"https://ror.org/038zpvz53","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210130352"]},{"id":"https://openalex.org/I4210152075","display_name":"Institut National d'Oncologie","ror":"https://ror.org/0132nee26","country_code":"MA","type":"facility","lineage":["https://openalex.org/I4210152075"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Sihame Lkhoyaali","raw_affiliation_strings":["Departement of medical oncologie , National Institute of Oncology , CHU Ibn Sina University Hospital Center , Rabat , MAR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departement of medical oncologie , National Institute of Oncology , CHU Ibn Sina University Hospital Center , Rabat , MAR","institution_ids":["https://openalex.org/I4210130352","https://openalex.org/I4210152075"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111139168","display_name":"El Ghissassi Ibrahim","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"El Ghissassi Ibrahim","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010882316","display_name":"Saber Boutayeb","orcid":"https://orcid.org/0000-0003-1642-9330","observed_orcids":["https://orcid.org/0000-0003-1642-9330"]},"institutions":[{"id":"https://openalex.org/I4210130352","display_name":"Centre Hospitalier Ibn Sina","ror":"https://ror.org/038zpvz53","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210130352"]},{"id":"https://openalex.org/I4210152075","display_name":"Institut National d'Oncologie","ror":"https://ror.org/0132nee26","country_code":"MA","type":"facility","lineage":["https://openalex.org/I4210152075"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Boutayeb Saber","raw_affiliation_strings":["Departement of medical oncologie , National Institute of Oncology , CHU Ibn Sina University Hospital Center , Rabat , MAR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departement of medical oncologie , National Institute of Oncology , CHU Ibn Sina University Hospital Center , Rabat , MAR","institution_ids":["https://openalex.org/I4210130352","https://openalex.org/I4210152075"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110124398","display_name":"M\ufffdrabti Hind","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130352","display_name":"Centre Hospitalier Ibn Sina","ror":"https://ror.org/038zpvz53","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210130352"]},{"id":"https://openalex.org/I4210152075","display_name":"Institut National d'Oncologie","ror":"https://ror.org/0132nee26","country_code":"MA","type":"facility","lineage":["https://openalex.org/I4210152075"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Mrabti Hind","raw_affiliation_strings":["Departement of medical oncologie , National Institute of Oncology , CHU Ibn Sina University Hospital Center , Rabat , MAR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departement of medical oncologie , National Institute of Oncology , CHU Ibn Sina University Hospital Center , Rabat , MAR","institution_ids":["https://openalex.org/I4210130352","https://openalex.org/I4210152075"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029203954","display_name":"Errihani Hassan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130352","display_name":"Centre Hospitalier Ibn Sina","ror":"https://ror.org/038zpvz53","country_code":"MA","type":"healthcare","lineage":["https://openalex.org/I4210130352"]},{"id":"https://openalex.org/I4210152075","display_name":"Institut National d'Oncologie","ror":"https://ror.org/0132nee26","country_code":"MA","type":"facility","lineage":["https://openalex.org/I4210152075"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Errihani Hassan","raw_affiliation_strings":["Departement of medical oncologie , National Institute of Oncology , CHU Ibn Sina University Hospital Center , Rabat , MAR"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departement of medical oncologie , National Institute of Oncology , CHU Ibn Sina University Hospital Center , Rabat , MAR","institution_ids":["https://openalex.org/I4210130352","https://openalex.org/I4210152075"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10202","display_name":"Lung Cancer Diagnosis and Treatment","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10202","display_name":"Lung Cancer Diagnosis and Treatment","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10417","display_name":"Lung Cancer Treatments and Mutations","score":0.008899999782443047,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12334","display_name":"Lung Cancer Research Studies","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lung-cancer","display_name":"lung cancer","score":0.9950000047683716},{"id":"https://openalex.org/keywords/care-pathways","display_name":"care pathways","score":0.9599999785423279},{"id":"https://openalex.org/keywords/treatment-delay","display_name":"treatment delay","score":0.8019999861717224},{"id":"https://openalex.org/keywords/molecular-testing","display_name":"molecular testing","score":0.8240000009536743},{"id":"https://openalex.org/keywords/adenocarcinoma","display_name":"adenocarcinoma","score":0.8320000171661377},{"id":"https://openalex.org/keywords/immunotherapy","display_name":"immunotherapy","score":0.7269999980926514},{"id":"https://openalex.org/keywords/targeted-therapy","display_name":"targeted therapy","score":0.996999979019165},{"id":"https://openalex.org/keywords/loss-to-follow-up","display_name":"loss to follow-up","score":0.8299999833106995},{"id":"https://openalex.org/keywords/delayed-diagnosis","display_name":"delayed diagnosis","score":0.5569999814033508},{"id":"https://openalex.org/keywords/morocco","display_name":"Morocco","score":0.4480000138282776}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.921500027179718},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.6736999750137329},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.5889000296592712},{"id":"https://openalex.org/C195910791","wikidata":"https://www.wikidata.org/wiki/Q1324077","display_name":"Medical record","level":2,"score":0.5385000109672546},{"id":"https://openalex.org/C2779399171","wikidata":"https://www.wikidata.org/wiki/Q1483951","display_name":"Malignancy","level":2,"score":0.5231000185012817},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5062000155448914},{"id":"https://openalex.org/C2781182431","wikidata":"https://www.wikidata.org/wiki/Q356033","display_name":"Adenocarcinoma","level":3,"score":0.47099998593330383},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.45590001344680786},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.4099999964237213},{"id":"https://openalex.org/C2994302464","wikidata":"https://www.wikidata.org/wiki/Q1774706","display_name":"Care pathway","level":3,"score":0.40689998865127563},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.39989998936653137},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.37619999051094055},{"id":"https://openalex.org/C22467394","wikidata":"https://www.wikidata.org/wiki/Q849359","display_name":"Multidisciplinary approach","level":2,"score":0.3727000057697296},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.36480000615119934},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.32199999690055847},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.32120001316070557},{"id":"https://openalex.org/C2778715236","wikidata":"https://www.wikidata.org/wiki/Q55622662","display_name":"Discontinuation","level":2,"score":0.3203999996185303},{"id":"https://openalex.org/C2777601897","wikidata":"https://www.wikidata.org/wiki/Q3409113","display_name":"Presentation (obstetrics)","level":2,"score":0.29190000891685486},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.2831000089645386},{"id":"https://openalex.org/C2781187634","wikidata":"https://www.wikidata.org/wiki/Q20969980","display_name":"KRAS","level":4,"score":0.273499995470047},{"id":"https://openalex.org/C2989236134","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Patient care","level":2,"score":0.26409998536109924},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.26260000467300415},{"id":"https://openalex.org/C2781230642","wikidata":"https://www.wikidata.org/wiki/Q492646","display_name":"Targeted therapy","level":3,"score":0.26100000739097595},{"id":"https://openalex.org/C3018838755","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Medical care","level":2,"score":0.25369998812675476},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2526000142097473}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.70780/medpeer.000qgov","doi":"https://doi.org/10.70780/medpeer.000qgov","is_oa":true,"landing_page_url":"https://doi.org/10.70780/medpeer.000qgov","pdf_url":"http://www.medpeerpublishers.com/articles/120.pdf","source":{"id":"https://openalex.org/S5407048740","display_name":"MedPeer publisher","issn_l":"3066-2737","issn":["3066-2737"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"MedPeer publisher","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.70780/medpeer.000qgov","doi":"https://doi.org/10.70780/medpeer.000qgov","is_oa":true,"landing_page_url":"https://doi.org/10.70780/medpeer.000qgov","pdf_url":"http://www.medpeerpublishers.com/articles/120.pdf","source":{"id":"https://openalex.org/S5407048740","display_name":"MedPeer publisher","issn_l":"3066-2737","issn":["3066-2737"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"MedPeer publisher","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4414108317.pdf","grobid_xml":"https://content.openalex.org/works/W4414108317.grobid-xml"},"referenced_works_count":7,"referenced_works":["https://openalex.org/W2028032813","https://openalex.org/W2062375422","https://openalex.org/W2109529837","https://openalex.org/W2280957887","https://openalex.org/W3128646645","https://openalex.org/W3130104331","https://openalex.org/W4315754639"],"related_works":["https://openalex.org/W2982028503","https://openalex.org/W7213293752","https://openalex.org/W4283705940","https://openalex.org/W4406472738","https://openalex.org/W2556966058","https://openalex.org/W2893044689","https://openalex.org/W4304974917","https://openalex.org/W2567739178","https://openalex.org/W4416636054","https://openalex.org/W2962888417"],"abstract_inverted_index":{"Introduction:":[0],"Primary":[1],"lung":[2,53,216],"cancer":[3,54,217],"remains":[4],"the":[5,16,33,46,58,71,116,144,160,191,212],"leading":[6],"cause":[7],"of":[8,52,61,88,159,196,215],"cancer-related":[9],"mortality":[10],"worldwide.":[11],"In":[12],"Morocco,":[13],"it":[14],"represents":[15],"most":[17],"common":[18],"malignancy":[19],"in":[20,64,70,155,211,240],"men,":[21],"with":[22,128],"often":[23],"late":[24],"presentation":[25],"and":[26,49,74,94,102,107,115,178,187,237],"limited":[27],"access":[28,77,222,241],"to":[29,40,76,78,200,223,230,242],"therapeutic":[30,103],"innovations.":[31],"Improving":[32],"care":[34,72,213],"pathway":[35,73,214],"is":[36],"a":[37,84,129],"major":[38],"challenge":[39],"optimize":[41],"management.":[42],"Objective:":[43],"To":[44],"evaluate":[45],"clinical,":[47],"histological,":[48],"molecular":[50,105,192],"characteristics":[51],"patients":[55,90,134,197],"managed":[56],"at":[57,123,137,140],"National":[59],"Institute":[60],"Oncology":[62],"(NIO)":[63],"Rabat,":[65],"by":[66],"identifying":[67],"key":[68],"delays":[69,99,171,210],"barriers":[75],"precision":[79],"medicine.":[80,244],"Methods:":[81],"This":[82,206],"was":[83,125,143,151,172],"retrospective":[85],"descriptive":[86],"study":[87,207],"100":[89],"diagnosed":[91],"between":[92,100,175],"September":[93],"December":[95],"2022.":[96],"Data":[97],"including":[98],"diagnostic":[101,235],"steps,":[104],"profiles,":[106],"treatment":[108,185,203],"modalities,":[109],"were":[110,136,198],"extracted":[111],"from":[112],"medical":[113,179],"records":[114],"ENOVA":[117],"system,.":[118],"Results:":[119],"The":[120,169],"mean":[121],"age":[122],"diagnosis":[124,177],"64":[126],"years,":[127],"male":[130],"predominance":[131],"(86%).":[132],"Most":[133],"(71%)":[135],"stage":[138],"IV":[139],"diagnosis.":[141],"Adenocarcinoma":[142],"predominant":[145],"histological":[146,176],"subtype":[147],"(64%).":[148],"Molecular":[149],"testing":[150],"incomplete":[152],"or":[153,166],"absent":[154],"more":[156],"than":[157],"half":[158],"patients.":[161],"No":[162],"patient":[163],"received":[164],"immunotherapy":[165],"targeted":[167],"therapy.":[168],"average":[170],"13":[173],"days":[174,183,189],"record":[180],"opening,":[181],"44":[182],"until":[184],"initiation,":[186],"61":[188],"for":[190],"results.":[193],"Moreover,":[194],"42%":[195],"lost":[199],"follow-up":[201],"before":[202],"initiation.":[204],"Conclusion:":[205],"highlights":[208],"significant":[209],"patients,":[218],"which":[219],"can":[220],"compromise":[221],"innovative":[224],"treatments.":[225],"Urgent":[226],"measures":[227],"are":[228],"needed":[229],"improve":[231],"multidisciplinary":[232],"coordination,":[233],"reduce":[234],"delays,":[236],"ensure":[238],"equity":[239],"personalized":[243]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2025-10-10T00:00:00"}