{"id":"https://openalex.org/W4414101571","doi":"https://doi.org/10.36106/paripex/6101764","title":"CORRELATION BETWEEN INTRA-RETINAL CYST DIMENSIONS AND VISION IN DME: AN OCT-BASED STUDY","display_name":"CORRELATION BETWEEN INTRA-RETINAL CYST DIMENSIONS AND VISION IN DME: AN OCT-BASED STUDY","publication_year":2025,"publication_date":"2025-08-15","ids":{"openalex":"https://openalex.org/W4414101571","doi":"https://doi.org/10.36106/paripex/6101764"},"language":"en","primary_location":{"id":"doi:10.36106/paripex/6101764","doi":"https://doi.org/10.36106/paripex/6101764","is_oa":true,"landing_page_url":"https://doi.org/10.36106/paripex/6101764","pdf_url":"https://doi.org/10.36106/paripex/6101764","source":{"id":"https://openalex.org/S2765053643","display_name":"PARIPEX-INDIAN JOURNAL OF RESEARCH","issn_l":"2250-1991","issn":["2250-1991"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320570","host_organization_name":"World Wide Journals","host_organization_lineage":["https://openalex.org/P4310320570"],"host_organization_lineage_names":["World Wide Journals"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PARIPEX INDIAN JOURNAL OF RESEARCH","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.36106/paripex/6101764","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5107127073","display_name":"Ruma Das Debsikdar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802488231","display_name":"Silchar Medical College and Hospital","ror":"https://ror.org/01cce5t38","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2802488231"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Ruma Das Debsikdar","raw_affiliation_strings":["Professor and Head of Department, Dept. of Ophthalmology, Silchar Medical College And Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Professor and Head of Department, Dept. of Ophthalmology, Silchar Medical College And Hospital","institution_ids":["https://openalex.org/I2802488231"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5119580020","display_name":"Krishnapriya J Kaimal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802488231","display_name":"Silchar Medical College and Hospital","ror":"https://ror.org/01cce5t38","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2802488231"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Krishnapriya J Kaimal","raw_affiliation_strings":["Post Graduate Trainee, 3 Year, Dept. of Ophthalmology, Silchar Medical College And Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Post Graduate Trainee, 3 Year, Dept. of Ophthalmology, Silchar Medical College And Hospital","institution_ids":["https://openalex.org/I2802488231"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100746290","display_name":"Tanveer Ahmed","orcid":"https://orcid.org/0000-0001-9346-2500","observed_orcids":["https://orcid.org/0000-0001-9346-2500"]},"institutions":[{"id":"https://openalex.org/I2802488231","display_name":"Silchar Medical College and Hospital","ror":"https://ror.org/01cce5t38","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2802488231"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Tanveer Ahmed","raw_affiliation_strings":["Registrar, Dept. of Ophthalmology, Silchar Medical College And Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Registrar, Dept. of Ophthalmology, Silchar Medical College And Hospital","institution_ids":["https://openalex.org/I2802488231"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030040305","display_name":"Nirmal Kumar","orcid":"https://orcid.org/0000-0001-9316-8010","observed_orcids":["https://orcid.org/0000-0001-9316-8010"]},"institutions":[{"id":"https://openalex.org/I2802488231","display_name":"Silchar Medical College and Hospital","ror":"https://ror.org/01cce5t38","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2802488231"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Nirmal Kumar","raw_affiliation_strings":["Post graduate Trainee, 3 Year, Dept. of Ophthalmology, Silchar Medical College And Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Post graduate Trainee, 3 Year, Dept. of Ophthalmology, Silchar Medical College And Hospital","institution_ids":["https://openalex.org/I2802488231"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103689628","display_name":"Kanakdeep Sharma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802488231","display_name":"Silchar Medical College and Hospital","ror":"https://ror.org/01cce5t38","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2802488231"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Kanakdeep Sharma","raw_affiliation_strings":["Post graduate Trainee, 3 Year, Dept. of Ophthalmology, Silchar Medical College And Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Post graduate Trainee, 3 Year, Dept. of Ophthalmology, Silchar Medical College And Hospital","institution_ids":["https://openalex.org/I2802488231"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108756338","display_name":"Rajneel Bhattacharjee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802488231","display_name":"Silchar Medical College and Hospital","ror":"https://ror.org/01cce5t38","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2802488231"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Rajneel Bhattacharjee","raw_affiliation_strings":["Registrar, Dept. of Ophthalmology, Silchar Medical College And Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Registrar, Dept. of Ophthalmology, Silchar Medical College And Hospital","institution_ids":["https://openalex.org/I2802488231"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I2802488231"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.28328218,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"46","last_page":"48"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11377","display_name":"Retinal and Macular Surgery","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11194","display_name":"Ocular Diseases and Beh\u00e7et\u2019s Syndrome","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diabetic-macular-edema","display_name":"diabetic macular edema","score":0.9990000128746033},{"id":"https://openalex.org/keywords/intraretinal-cysts","display_name":"intraretinal cysts","score":0.9440000057220459},{"id":"https://openalex.org/keywords/best-corrected-visual-acuity","display_name":"best-corrected visual acuity","score":0.9879999756813049},{"id":"https://openalex.org/keywords/central-macular-thickness","display_name":"central macular thickness","score":0.9539999961853027},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.906000018119812},{"id":"https://openalex.org/keywords/diabetic-retinopathy","display_name":"diabetic retinopathy","score":0.9850000143051147},{"id":"https://openalex.org/keywords/ellipsoid-zone-disruption","display_name":"ellipsoid zone disruption","score":0.7580000162124634},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.9150000214576721},{"id":"https://openalex.org/keywords/anti-vegf-therapy","display_name":"anti-VEGF therapy","score":0.9179999828338623},{"id":"https://openalex.org/keywords/corticosteroid-therapy","display_name":"corticosteroid therapy","score":0.8650000095367432}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8668000102043152},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.7633000016212463},{"id":"https://openalex.org/C2780597408","wikidata":"https://www.wikidata.org/wiki/Q193211","display_name":"Cyst","level":2,"score":0.7585999965667725},{"id":"https://openalex.org/C2777063560","wikidata":"https://www.wikidata.org/wiki/Q3366043","display_name":"Pars plana","level":4,"score":0.6172999739646912},{"id":"https://openalex.org/C2779829184","wikidata":"https://www.wikidata.org/wiki/Q631361","display_name":"Diabetic retinopathy","level":3,"score":0.5778999924659729},{"id":"https://openalex.org/C117220453","wikidata":"https://www.wikidata.org/wiki/Q5172842","display_name":"Correlation","level":2,"score":0.5702999830245972},{"id":"https://openalex.org/C2778818243","wikidata":"https://www.wikidata.org/wiki/Q899552","display_name":"Optical coherence tomography","level":2,"score":0.5504000186920166},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.5091999769210815},{"id":"https://openalex.org/C2778257484","wikidata":"https://www.wikidata.org/wiki/Q555066","display_name":"Visual acuity","level":2,"score":0.5063999891281128},{"id":"https://openalex.org/C2780347916","wikidata":"https://www.wikidata.org/wiki/Q1813737","display_name":"Macular edema","level":3,"score":0.41600000858306885},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.3961000144481659},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.3483000099658966},{"id":"https://openalex.org/C2781242345","wikidata":"https://www.wikidata.org/wiki/Q924295","display_name":"Vitrectomy","level":3,"score":0.3336000144481659},{"id":"https://openalex.org/C119767625","wikidata":"https://www.wikidata.org/wiki/Q618211","display_name":"Optometry","level":1,"score":0.3172000050544739},{"id":"https://openalex.org/C2776403814","wikidata":"https://www.wikidata.org/wiki/Q27429789","display_name":"Macular degeneration","level":2,"score":0.3149000108242035},{"id":"https://openalex.org/C2985127711","wikidata":"https://www.wikidata.org/wiki/Q631361","display_name":"Diabetic macular edema","level":4,"score":0.3075999915599823},{"id":"https://openalex.org/C2777910003","wikidata":"https://www.wikidata.org/wiki/Q1707292","display_name":"Asymptomatic","level":2,"score":0.30630001425743103},{"id":"https://openalex.org/C2986115478","wikidata":"https://www.wikidata.org/wiki/Q186290","display_name":"Positive correlation","level":2,"score":0.29989999532699585},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.2800000011920929},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2745000123977661},{"id":"https://openalex.org/C2988405389","wikidata":"https://www.wikidata.org/wiki/Q6987247","display_name":"Negative correlation","level":2,"score":0.25519999861717224},{"id":"https://openalex.org/C2778313320","wikidata":"https://www.wikidata.org/wiki/Q550455","display_name":"Retinopathy","level":3,"score":0.25130000710487366}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.36106/paripex/6101764","doi":"https://doi.org/10.36106/paripex/6101764","is_oa":true,"landing_page_url":"https://doi.org/10.36106/paripex/6101764","pdf_url":"https://doi.org/10.36106/paripex/6101764","source":{"id":"https://openalex.org/S2765053643","display_name":"PARIPEX-INDIAN JOURNAL OF RESEARCH","issn_l":"2250-1991","issn":["2250-1991"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320570","host_organization_name":"World Wide Journals","host_organization_lineage":["https://openalex.org/P4310320570"],"host_organization_lineage_names":["World Wide Journals"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PARIPEX INDIAN JOURNAL OF RESEARCH","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.36106/paripex/6101764","doi":"https://doi.org/10.36106/paripex/6101764","is_oa":true,"landing_page_url":"https://doi.org/10.36106/paripex/6101764","pdf_url":"https://doi.org/10.36106/paripex/6101764","source":{"id":"https://openalex.org/S2765053643","display_name":"PARIPEX-INDIAN JOURNAL OF RESEARCH","issn_l":"2250-1991","issn":["2250-1991"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320570","host_organization_name":"World Wide Journals","host_organization_lineage":["https://openalex.org/P4310320570"],"host_organization_lineage_names":["World Wide Journals"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PARIPEX INDIAN JOURNAL OF RESEARCH","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4414101571.pdf","grobid_xml":"https://content.openalex.org/works/W4414101571.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4387265590","https://openalex.org/W1995904975","https://openalex.org/W3032712071","https://openalex.org/W4389019322","https://openalex.org/W2034516402","https://openalex.org/W3040090327","https://openalex.org/W2756647615","https://openalex.org/W83614871","https://openalex.org/W2979526170","https://openalex.org/W806426592"],"abstract_inverted_index":{"This":[0],"retrospective,":[1],"cross-sectional":[2],"study":[3],"aimed":[4],"to":[5,132,212,246,254],"evaluate":[6],"the":[7,46,125,133,203,208],"correlation":[8,167,186],"between":[9],"intra-retinal":[10,67],"cyst":[11,117,126,161,181,220,264],"dimensions":[12],"and":[13,40,64,108,116,142,229,258],"best-corrected":[14],"visual":[15],"acuity":[16],"(BCVA)":[17],"in":[18,124,227],"diabetic":[19,41],"macular":[20,76,113],"edema":[21],"(DME)":[22],"patients":[23,34],"using":[24],"spectral-domain":[25],"optical":[26],"coherence":[27],"tomography":[28],"(OCT).":[29],"Eighty-two":[30],"eyes":[31],"of":[32,48,111,202,241],"82":[33],"with":[35,66,168,200],"type":[36],"2":[37],"diabetes":[38],"mellitus":[39],"retinopathy":[42],"were":[43,53,198],"included,":[44],"meeting":[45],"criterion":[47],"BCVA":[49,99,120,169],"\u2265":[50],"20/200.":[51],"Patients":[52],"categorized":[54],"into":[55],"two":[56],"groups:":[57],"DME":[58,65],"without":[59],"cysts":[60,68,197],"(n":[61,69],"=":[62,70,171,188],"38)":[63],"44).":[71],"Exclusion":[72],"criteria":[73],"included":[74,98],"prior":[75],"grid":[77],"laser":[78],"photocoagulation,":[79],"pars":[80],"plana":[81],"vitrectomy,":[82],"significant":[83],"media":[84],"opacity,":[85],"other":[86],"ocular":[87],"conditions":[88],"impeding":[89],"OCT":[90,109],"assessment,":[91],"or":[92,239,243],"incomplete":[93],"records.":[94],"Comprehensive":[95],"ophthalmic":[96],"evaluation":[97],"measurement":[100,110],"(logMAR),":[101],"slit-lamp":[102],"biomicroscopy,":[103],"Goldmann":[104],"applanation":[105],"tonometry,":[106],"fundoscopy,":[107],"central":[112],"thickness":[114],"(CMT)":[115],"dimensions.":[118],"Mean":[119],"was":[121,145],"significantly":[122,146],"worse":[123],"group":[127,135],"(0.74":[128],"\u00b1":[129,137,149,154],"0.15)":[130],"compared":[131],"non-cyst":[134],"(0.46":[136],"0.12;":[138],"p":[139,157,176,193],"<":[140,158,177,194],"0.001),":[141,178],"mean":[143],"CMT":[144],"greater":[147],"(398":[148],"46":[150],"\u03bcm":[151],"vs.":[152],"322":[153],"34":[155],"m;":[156],"0.001).":[159,195],"Vertical":[160],"size":[162,182,221],"demonstrated":[163],"a":[164,184,223],"strong":[165],"positive":[166],"(r":[170,187],"0.64,":[172],"95%":[173,190],"CI:":[174,191],"0.48\u20130.76;":[175],"while":[179],"horizontal":[180],"showed":[183],"moderate":[185],"0.59,":[189],"0.42\u20130.73;":[192],"Larger":[196],"associated":[199],"disruption":[201],"outer":[204],"retinal":[205],"layers,":[206],"particularly":[207],"ellipsoid":[209],"zone,":[210],"contributing":[211],"poorer":[213],"vision.":[214,248],"These":[215],"findings":[216],"suggest":[217],"that":[218],"intraretinal":[219],"is":[222],"valuable":[224],"prognostic":[225],"biomarker":[226],"DME,":[228],"OCT-based":[230],"assessment":[231],"could":[232],"guide":[233],"timely":[234],"intervention,":[235],"including":[236],"early":[237],"initiation":[238],"intensification":[240],"anti-VEGF":[242],"corticosteroid":[244],"therapy":[245],"preserve":[247],"Further":[249],"prospective":[250],"studies":[251],"are":[252],"warranted":[253],"validate":[255],"these":[256],"results":[257],"assess":[259],"treatment":[260],"outcomes":[261],"based":[262],"on":[263],"dimension":[265],"monitoring.":[266]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2025-10-10T00:00:00"}