{"id":"https://openalex.org/W4414065136","doi":"https://doi.org/10.3390/ejihpe15090181","title":"Cardiovascular Health, Assessed by Life\u2019s Essential 8, Is Associated with Lower Risk of Disability Among Older, Community-Dwelling Men and Women","display_name":"Cardiovascular Health, Assessed by Life\u2019s Essential 8, Is Associated with Lower Risk of Disability Among Older, Community-Dwelling Men and Women","publication_year":2025,"publication_date":"2025-09-08","ids":{"openalex":"https://openalex.org/W4414065136","doi":"https://doi.org/10.3390/ejihpe15090181","pmid":"https://pubmed.ncbi.nlm.nih.gov/41002762","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12468947"},"language":"en","primary_location":{"id":"doi:10.3390/ejihpe15090181","doi":"https://doi.org/10.3390/ejihpe15090181","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ejihpe15090181","pdf_url":"https://www.mdpi.com/2254-9625/15/9/181/pdf?version=1757325586","source":{"id":"https://openalex.org/S2739472552","display_name":"European Journal of Investigation in Health Psychology and Education","issn_l":"2174-8144","issn":["2174-8144","2254-9625"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","latindex","norway-1","poland-20","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Investigation in Health, Psychology and Education","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2254-9625/15/9/181/pdf?version=1757325586","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035792921","display_name":"Xin Li","orcid":"https://orcid.org/0000-0002-1118-5288","observed_orcids":["https://orcid.org/0000-0002-1118-5288"]},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xin Li","raw_affiliation_strings":["Department of Exercise and Nutrition Sciences, Milken Institute School of Public Health, The George Washington University, Washington, DC 20052, USA"],"raw_orcid":"https://orcid.org/0000-0002-1118-5288","affiliations":[{"raw_affiliation_string":"Department of Exercise and Nutrition Sciences, Milken Institute School of Public Health, The George Washington University, Washington, DC 20052, USA","institution_ids":["https://openalex.org/I193531525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114085464","display_name":"Yichen Jin","orcid":"https://orcid.org/0000-0001-9207-2535","observed_orcids":["https://orcid.org/0000-0001-9207-2535"]},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Yichen Jin","raw_affiliation_strings":["Department of Exercise and Nutrition Sciences, Milken Institute School of Public Health, The George Washington University, Washington, DC 20052, USA"],"raw_orcid":"https://orcid.org/0000-0001-9207-2535","affiliations":[{"raw_affiliation_string":"Department of Exercise and Nutrition Sciences, Milken Institute School of Public Health, The George Washington University, Washington, DC 20052, USA","institution_ids":["https://openalex.org/I193531525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091741059","display_name":"Stefania Bandinelli","orcid":"https://orcid.org/0000-0002-6491-0850","observed_orcids":["https://orcid.org/0000-0002-6491-0850"]},"institutions":[{"id":"https://openalex.org/I4210102885","display_name":"Azienda Sanitaria di Firenze","ror":"https://ror.org/01cfgbq85","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210102885"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Stefania Bandinelli","raw_affiliation_strings":["Geriatric Unit, Azienda Sanitaria Firenze (ASF), 50137 Florence, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Geriatric Unit, Azienda Sanitaria Firenze (ASF), 50137 Florence, Italy","institution_ids":["https://openalex.org/I4210102885"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048196698","display_name":"Luigi Ferrucci","orcid":"https://orcid.org/0000-0002-6273-1613","observed_orcids":["https://orcid.org/0000-0002-6273-1613"]},"institutions":[{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Luigi Ferrucci","raw_affiliation_strings":["Translational Gerontology Branch, National Institute on Aging, Baltimore, MD 21224, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Translational Gerontology Branch, National Institute on Aging, Baltimore, MD 21224, USA","institution_ids":["https://openalex.org/I4210136897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079276216","display_name":"Toshiko Tanaka","orcid":"https://orcid.org/0000-0002-4161-3829","observed_orcids":["https://orcid.org/0000-0002-4161-3829"]},"institutions":[{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Toshiko Tanaka","raw_affiliation_strings":["Translational Gerontology Branch, National Institute on Aging, Baltimore, MD 21224, USA"],"raw_orcid":"https://orcid.org/0000-0002-4161-3829","affiliations":[{"raw_affiliation_string":"Translational Gerontology Branch, National Institute on Aging, Baltimore, MD 21224, USA","institution_ids":["https://openalex.org/I4210136897"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089467620","display_name":"Sameera A. Talegawkar","orcid":"https://orcid.org/0000-0003-2612-5728","observed_orcids":["https://orcid.org/0000-0003-2612-5728"]},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sameera A. Talegawkar","raw_affiliation_strings":["Department of Exercise and Nutrition Sciences, Milken Institute School of Public Health, The George Washington University, Washington, DC 20052, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Exercise and Nutrition Sciences, Milken Institute School of Public Health, The George Washington University, Washington, DC 20052, USA","institution_ids":["https://openalex.org/I193531525"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5114085464"],"corresponding_institution_ids":["https://openalex.org/I193531525"],"apc_list":{"value":1400,"currency":"CHF","value_usd":1689},"apc_paid":{"value":1400,"currency":"CHF","value_usd":1689},"fwci":0.6933,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.74802083,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"15","issue":"9","first_page":"181","last_page":"181"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13522","display_name":"Cardiovascular Health and Risk Factors","score":0.9409000277519226,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13522","display_name":"Cardiovascular Health and Risk Factors","score":0.9409000277519226,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12811","display_name":"Aging, Health, and Disability","score":0.05130000039935112,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cardiovascular-health","display_name":"cardiovascular health","score":0.9959999918937683},{"id":"https://openalex.org/keywords/life-s-essential-8","display_name":"Life's Essential 8","score":0.9980000257492065},{"id":"https://openalex.org/keywords/disability","display_name":"disability","score":0.8619999885559082},{"id":"https://openalex.org/keywords/activities-of-daily-living","display_name":"activities of daily living","score":0.8539999723434448},{"id":"https://openalex.org/keywords/instrumental-activities-of-daily-living","display_name":"instrumental activities of daily living","score":1.0},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.9810000061988831},{"id":"https://openalex.org/keywords/healthy-aging","display_name":"healthy aging","score":0.7070000171661377},{"id":"https://openalex.org/keywords/functional-independence","display_name":"functional independence","score":0.968999981880188},{"id":"https://openalex.org/keywords/community-dwelling-elderly","display_name":"community-dwelling older adults","score":0.7110000252723694},{"id":"https://openalex.org/keywords/inchianti-cohort","display_name":"InCHIANTI cohort","score":0.7860000133514404}],"concepts":[{"id":"https://openalex.org/C79544238","wikidata":"https://www.wikidata.org/wiki/Q423243","display_name":"Activities of daily living","level":2,"score":0.8543000221252441},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7487999796867371},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.5562999844551086},{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.5295000076293945},{"id":"https://openalex.org/C176217482","wikidata":"https://www.wikidata.org/wiki/Q860554","display_name":"Metric (unit)","level":2,"score":0.40400001406669617},{"id":"https://openalex.org/C2779668873","wikidata":"https://www.wikidata.org/wiki/Q6693756","display_name":"Lower risk","level":3,"score":0.3808000087738037},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.37560001015663147},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.36890000104904175},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.3334999978542328},{"id":"https://openalex.org/C3018284874","wikidata":"https://www.wikidata.org/wiki/Q389735","display_name":"Cardiovascular health","level":3,"score":0.3240000009536743},{"id":"https://openalex.org/C35651441","wikidata":"https://www.wikidata.org/wiki/Q625303","display_name":"Independence (probability theory)","level":2,"score":0.32260000705718994},{"id":"https://openalex.org/C138816342","wikidata":"https://www.wikidata.org/wiki/Q189603","display_name":"Public health","level":2,"score":0.31869998574256897},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.31790000200271606},{"id":"https://openalex.org/C3019887659","wikidata":"https://www.wikidata.org/wiki/Q191089","display_name":"Older people","level":2,"score":0.2987000048160553},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.29339998960494995},{"id":"https://openalex.org/C3020255362","wikidata":"https://www.wikidata.org/wiki/Q747883","display_name":"Physical activity","level":2,"score":0.2734000086784363},{"id":"https://openalex.org/C82789193","wikidata":"https://www.wikidata.org/wiki/Q2142611","display_name":"Relative risk","level":3,"score":0.27129998803138733},{"id":"https://openalex.org/C2780176501","wikidata":"https://www.wikidata.org/wiki/Q5690755","display_name":"Health and Retirement Study","level":2,"score":0.26829999685287476},{"id":"https://openalex.org/C12174686","wikidata":"https://www.wikidata.org/wiki/Q1058438","display_name":"Risk assessment","level":2,"score":0.267300009727478}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3390/ejihpe15090181","doi":"https://doi.org/10.3390/ejihpe15090181","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ejihpe15090181","pdf_url":"https://www.mdpi.com/2254-9625/15/9/181/pdf?version=1757325586","source":{"id":"https://openalex.org/S2739472552","display_name":"European Journal of Investigation in Health Psychology and Education","issn_l":"2174-8144","issn":["2174-8144","2254-9625"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","latindex","norway-1","poland-20","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Investigation in Health, Psychology and Education","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:11277290","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12468947","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:41002762","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41002762","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European journal of investigation in health, psychology and education","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12468947","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12468947/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Eur J Investig Health Psychol Educ","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:667a7ddbc0f742ca97e80d166afa2c04","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/667a7ddbc0f742ca97e80d166afa2c04","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"European Journal of Investigation in Health, Psychology and Education, Vol 15, Iss 9, p 181 (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/ejihpe15090181","doi":"https://doi.org/10.3390/ejihpe15090181","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ejihpe15090181","pdf_url":"https://www.mdpi.com/2254-9625/15/9/181/pdf?version=1757325586","source":{"id":"https://openalex.org/S2739472552","display_name":"European Journal of Investigation in Health Psychology and Education","issn_l":"2174-8144","issn":["2174-8144","2254-9625"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","latindex","norway-1","poland-20","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Journal of Investigation in Health, Psychology and Education","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G4901144228","display_name":"Associations between ideal cardiovascular health, frailty & age related declines","funder_award_id":"R03AG048377","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G6062929773","display_name":"Dietary patterns and hearing loss in middle aged and older Americans","funder_award_id":"R03AG065861","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"}],"funders":[{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4414065136.pdf","grobid_xml":"https://content.openalex.org/works/W4414065136.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W1562952622","https://openalex.org/W1671449442","https://openalex.org/W1967974729","https://openalex.org/W1985305462","https://openalex.org/W2022297880","https://openalex.org/W2039022968","https://openalex.org/W2081082038","https://openalex.org/W2091097500","https://openalex.org/W2108429535","https://openalex.org/W2109396042","https://openalex.org/W2111371354","https://openalex.org/W2114656311","https://openalex.org/W2128529067","https://openalex.org/W2134270369","https://openalex.org/W2136127141","https://openalex.org/W2150654772","https://openalex.org/W2152577472","https://openalex.org/W2156848121","https://openalex.org/W2183907399","https://openalex.org/W2289366543","https://openalex.org/W2318855346","https://openalex.org/W2463967081","https://openalex.org/W2470404394","https://openalex.org/W2523136753","https://openalex.org/W2765701841","https://openalex.org/W2806353907","https://openalex.org/W2880270799","https://openalex.org/W2962718754","https://openalex.org/W2981655389","https://openalex.org/W3081639753","https://openalex.org/W3134156050","https://openalex.org/W3200923957","https://openalex.org/W4206462391","https://openalex.org/W4210449137","https://openalex.org/W4232387401","https://openalex.org/W4283695295","https://openalex.org/W4287834666","https://openalex.org/W4306784268","https://openalex.org/W4366602672","https://openalex.org/W4381569916","https://openalex.org/W4386629069","https://openalex.org/W4392763295","https://openalex.org/W4401758682"],"related_works":["https://openalex.org/W2806353907","https://openalex.org/W4412200651","https://openalex.org/W2765701841","https://openalex.org/W7167959427","https://openalex.org/W4378191884","https://openalex.org/W4404353389","https://openalex.org/W7214079824","https://openalex.org/W2289366543","https://openalex.org/W2887503056","https://openalex.org/W3194951437"],"abstract_inverted_index":{"Our":[0],"study":[1,27],"examined":[2],"the":[3,11,25,44,55,62,82,106,156,177],"associations":[4],"between":[5],"overall":[6,70],"cardiovascular":[7],"health":[8,195],"(CVH)":[9],"and":[10,30,37,61,95,135,166,169,190],"risk":[12,163],"of":[13,21,57,65,80,164,179],"disability":[14,97,192],"in":[15,204],"older":[16,150,209],"adults":[17],"over":[18,172],"16":[19],"years":[20,36],"follow-up.":[22],"Data":[23],"from":[24],"InCHIANTI":[26],"were":[28,114],"used":[29],"included":[31],"928":[32],"participants":[33],"aged":[34],"65":[35],"older.":[38],"Overall":[39],"CVH":[40,153,181,199],"was":[41,52,75,159],"measured":[42],"using":[43,105,144],"\u201cLife\u2019s":[45],"Essential":[46],"8\u201d":[47],"(LE8)":[48],"metric.":[49],"Disability":[50],"status":[51],"assessed":[53,154],"by":[54,155],"Activities":[56,64],"Daily":[58,66],"Living":[59,67],"(ADL)":[60],"Instrumental":[63],"(IADL).":[68],"Higher":[69,111],"LE8":[71,112,157],"score":[72],"at":[73],"baseline":[74],"associated":[76,116,160],"with":[77,117,161],"lower":[78,162],"risks":[79],"having":[81],"first":[83],"ADL":[84,118,165],"among":[85,208],"males":[86],"(hazard":[87],"ratio":[88,120],"[HR]":[89],"=":[90,93,100,103,123,126,130,139],"0.66,":[91],"p":[92,102,125,132,141],"0.001)":[94,134,143],"IADL":[96,136,167],"event":[98],"(HR":[99],"0.89,":[101],"0.016)":[104],"Cox":[107],"proportional":[108],"hazards":[109],"model.":[110],"scores":[113],"also":[115],"(odds":[119],"[OR]":[121],"(females)":[122],"0.80,":[124],"0.034;":[127],"OR":[128],"(males)":[129],"0.55,":[131],"<":[133,142],"worsening":[137,171],"(OR":[138],"0.72,":[140],"Generalized":[145],"Estimating":[146],"Equation":[147],"models.":[148],"Among":[149],"adults,":[151],"better":[152],"metric":[158],"disabilities":[168],"their":[170],"time.":[173],"These":[174],"findings":[175],"underscore":[176],"importance":[178],"promoting":[180],"as":[182],"a":[183],"key":[184],"strategy":[185],"to":[186],"support":[187],"healthy":[188],"aging":[189],"reduce":[191],"burden.":[193],"Public":[194],"interventions":[196],"that":[197],"target":[198],"components":[200],"may":[201],"be":[202],"effective":[203],"preserving":[205],"functional":[206],"independence":[207],"populations.":[210]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2025-10-10T00:00:00"}