{"id":"https://openalex.org/W4414049385","doi":"https://doi.org/10.3791/23876","title":"Injecting Self-Assembling Peptides and Neural Precursor Cells for Spinal Cord Repair in a Rat Model","display_name":"Injecting Self-Assembling Peptides and Neural Precursor Cells for Spinal Cord Repair in a Rat Model","publication_year":2025,"publication_date":"2025-09-04","ids":{"openalex":"https://openalex.org/W4414049385","doi":"https://doi.org/10.3791/23876"},"language":"en","primary_location":{"id":"doi:10.3791/23876","doi":"https://doi.org/10.3791/23876","is_oa":false,"landing_page_url":"https://doi.org/10.3791/23876","pdf_url":null,"source":{"id":"https://openalex.org/S7407064559","display_name":"Journal of Visualized Experiments","issn_l":"3065-5374","issn":["3065-5374"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Visualized Experiments","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.27529381,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10925","display_name":"Spinal Cord Injury Research","score":0.9628999829292297,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10925","display_name":"Spinal Cord Injury Research","score":0.9628999829292297,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10483","display_name":"Nerve injury and regeneration","score":0.031199999153614044,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11419","display_name":"Supramolecular Self-Assembly in Materials","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/spinal-cord-injury","display_name":"spinal cord injury","score":0.9300000071525574},{"id":"https://openalex.org/keywords/self-assembling-peptides","display_name":"self-assembling peptides","score":0.9520000219345093},{"id":"https://openalex.org/keywords/neural-progenitor-cells","display_name":"neural progenitor cells","score":0.9980000257492065},{"id":"https://openalex.org/keywords/cell-transplantation","display_name":"cell transplantation","score":0.5289999842643738},{"id":"https://openalex.org/keywords/tissue-remodeling","display_name":"tissue remodeling","score":0.6669999957084656},{"id":"https://openalex.org/keywords/cervical-spinal-cord","display_name":"cervical spinal cord","score":0.859000027179718},{"id":"https://openalex.org/keywords/rat-model","display_name":"rat model","score":0.6140000224113464}],"concepts":[{"id":"https://openalex.org/C2780775167","wikidata":"https://www.wikidata.org/wiki/Q9606","display_name":"Spinal cord","level":2,"score":0.7609000205993652},{"id":"https://openalex.org/C124964019","wikidata":"https://www.wikidata.org/wiki/Q11616062","display_name":"Precursor cell","level":3,"score":0.694599986076355},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.6535000205039978},{"id":"https://openalex.org/C3019114686","wikidata":"https://www.wikidata.org/wiki/Q3089676","display_name":"Rat model","level":2,"score":0.6445000171661377},{"id":"https://openalex.org/C2778334475","wikidata":"https://www.wikidata.org/wiki/Q1415275","display_name":"Spinal cord injury","level":3,"score":0.5072000026702881},{"id":"https://openalex.org/C2992459734","wikidata":"https://www.wikidata.org/wiki/Q43054","display_name":"Neural cell","level":3,"score":0.5037999749183655},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4959000051021576},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.44859999418258667},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.42800000309944153},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.4212999939918518},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.37529999017715454},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.36000001430511475},{"id":"https://openalex.org/C136834591","wikidata":"https://www.wikidata.org/wiki/Q2944097","display_name":"Neural stem cell","level":3,"score":0.3571000099182129},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3314000070095062},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3127000033855438},{"id":"https://openalex.org/C545706735","wikidata":"https://www.wikidata.org/wiki/Q9404","display_name":"Nervous system","level":2,"score":0.28369998931884766},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.2678000032901764},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.2612000107765198},{"id":"https://openalex.org/C2779632786","wikidata":"https://www.wikidata.org/wiki/Q920297","display_name":"Cord","level":2,"score":0.25459998846054077}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3791/23876","doi":"https://doi.org/10.3791/23876","is_oa":false,"landing_page_url":"https://doi.org/10.3791/23876","pdf_url":null,"source":{"id":"https://openalex.org/S7407064559","display_name":"Journal of Visualized Experiments","issn_l":"3065-5374","issn":["3065-5374"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Visualized Experiments","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8560000061988831,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4387497383","https://openalex.org/W2948807893","https://openalex.org/W2899084033","https://openalex.org/W2778153218","https://openalex.org/W2748952813","https://openalex.org/W1531601525","https://openalex.org/W4391375266","https://openalex.org/W2078814861","https://openalex.org/W2527526854","https://openalex.org/W2937445305"],"abstract_inverted_index":{"Source:":[0],"Zweckberger,":[1],"K.,":[2],"et":[3],"al.":[4],"Synergetic":[5],"Use":[6],"of":[7],"Neural":[8],"Precursor":[9],"Cells":[10],"and":[11],"Self-assembling":[12],"Peptides":[13],"in":[14,35],"Experimental":[15],"Cervical":[16],"Spinal":[17],"Cord":[18],"Injury.":[19],"J.":[20],"Vis.":[21],"Exp.":[22],"(2015).This":[23],"protocol":[24],"demonstrates":[25],"a":[26,36,51],"targeted":[27],"injection":[28],"approach":[29],"for":[30],"spinal":[31],"cord":[32],"injury":[33],"repair":[34],"rat":[37],"model.":[38],"It":[39],"involves":[40],"delivering":[41],"self-assembling":[42],"peptides":[43],"(SAPs)":[44],"into":[45],"the":[46,62,66],"lesion":[47,63],"core":[48],"to":[49,64],"create":[50],"supportive":[52],"scaffold,":[53],"followed":[54],"by":[55],"neural":[56],"precursor":[57],"cell":[58],"(NPC)":[59],"injections":[60],"around":[61],"remodel":[65],"tissue.":[67]},"counts_by_year":[],"updated_date":"2026-09-09T07:26:56.047234","created_date":"2025-10-10T00:00:00"}