{"id":"https://openalex.org/W4413993136","doi":"https://doi.org/10.3390/jcm14176238","title":"Diagnostic Accuracy of Exercise Stress Testing, Stress Echocardiography, Myocardial Scintigraphy, and Cardiac Magnetic Resonance for Obstructive Coronary Artery Disease: Systematic Reviews and Meta-Analyses of 104 Studies Published from 1990 to 2025","display_name":"Diagnostic Accuracy of Exercise Stress Testing, Stress Echocardiography, Myocardial Scintigraphy, and Cardiac Magnetic Resonance for Obstructive Coronary Artery Disease: Systematic Reviews and Meta-Analyses of 104 Studies Published from 1990 to 2025","publication_year":2025,"publication_date":"2025-09-04","ids":{"openalex":"https://openalex.org/W4413993136","doi":"https://doi.org/10.3390/jcm14176238","pmid":"https://pubmed.ncbi.nlm.nih.gov/40943997","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12429821"},"language":"en","primary_location":{"id":"doi:10.3390/jcm14176238","doi":"https://doi.org/10.3390/jcm14176238","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm14176238","pdf_url":null,"source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/jcm14176238","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088051972","display_name":"Andrea Sonaglioni","orcid":"https://orcid.org/0000-0001-7641-8831","observed_orcids":["https://orcid.org/0000-0001-7641-8831"]},"institutions":[{"id":"https://openalex.org/I4210094922","display_name":"MultiMedica","ror":"https://ror.org/01h8ey223","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094922","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Andrea Sonaglioni","raw_affiliation_strings":["Division of Cardiology, IRCCS MultiMedica, 20123 Milan, Italy"],"raw_orcid":"https://orcid.org/0000-0001-7641-8831","affiliations":[{"raw_affiliation_string":"Division of Cardiology, IRCCS MultiMedica, 20123 Milan, Italy","institution_ids":["https://openalex.org/I4210094922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062954442","display_name":"Alessio Polymeropoulos","orcid":"https://orcid.org/0000-0002-2652-3964","observed_orcids":["https://orcid.org/0000-0002-2652-3964"]},"institutions":[{"id":"https://openalex.org/I66752286","display_name":"University of Milano-Bicocca","ror":"https://ror.org/01ynf4891","country_code":"IT","type":"education","lineage":["https://openalex.org/I66752286"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Alessio Polymeropoulos","raw_affiliation_strings":["Department of Statistics and Quantitative Methods, University of Milano-Bicocca, 20126 Milan, Italy"],"raw_orcid":"https://orcid.org/0000-0002-2652-3964","affiliations":[{"raw_affiliation_string":"Department of Statistics and Quantitative Methods, University of Milano-Bicocca, 20126 Milan, Italy","institution_ids":["https://openalex.org/I66752286"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001651127","display_name":"Massimo Baravelli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094922","display_name":"MultiMedica","ror":"https://ror.org/01h8ey223","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094922","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Massimo Baravelli","raw_affiliation_strings":["Division of Cardiology, IRCCS MultiMedica, 20123 Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, IRCCS MultiMedica, 20123 Milan, Italy","institution_ids":["https://openalex.org/I4210094922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022436940","display_name":"Gian Luigi Nicolosi","orcid":"https://orcid.org/0000-0002-2218-2808","observed_orcids":["https://orcid.org/0000-0002-2218-2808"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gian Luigi Nicolosi","raw_affiliation_strings":["Division of Cardiology, Policlinico San Giorgio, 33170 Pordenone, Italy"],"raw_orcid":"https://orcid.org/0000-0002-2218-2808","affiliations":[{"raw_affiliation_string":"Division of Cardiology, Policlinico San Giorgio, 33170 Pordenone, Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103328111","display_name":"Michele Lombardo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210094922","display_name":"MultiMedica","ror":"https://ror.org/01h8ey223","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210094922","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Michele Lombardo","raw_affiliation_strings":["Division of Cardiology, IRCCS MultiMedica, 20123 Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, IRCCS MultiMedica, 20123 Milan, Italy","institution_ids":["https://openalex.org/I4210094922"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073353856","display_name":"Giuseppe Biondi\u2010Zoccai","orcid":"https://orcid.org/0000-0001-6103-8510","observed_orcids":["https://orcid.org/0000-0001-6103-8510"]},"institutions":[{"id":"https://openalex.org/I4210100680","display_name":"Maria Cecilia Hospital","ror":"https://ror.org/01wxb8362","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210100680"]},{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giuseppe Biondi-Zoccai","raw_affiliation_strings":["Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University, 04100 Latina, Italy","Maria Cecilia Hospital, GVM Care & Research, 48033 Cotignola, Italy"],"raw_orcid":"https://orcid.org/0000-0001-6103-8510","affiliations":[{"raw_affiliation_string":"Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University, 04100 Latina, Italy","institution_ids":["https://openalex.org/I861853513"]},{"raw_affiliation_string":"Maria Cecilia Hospital, GVM Care & Research, 48033 Cotignola, Italy","institution_ids":["https://openalex.org/I4210100680"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5088051972"],"corresponding_institution_ids":["https://openalex.org/I4210094922"],"apc_list":{"value":2600,"currency":"CHF","value_usd":3137},"apc_paid":{"value":2600,"currency":"CHF","value_usd":3137},"fwci":3.2446,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.95568322,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"14","issue":"17","first_page":"6238","last_page":"6238"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/obstructive-coronary-artery-disease","display_name":"obstructive coronary artery disease","score":0.925000011920929},{"id":"https://openalex.org/keywords/diagnostic-accuracy","display_name":"diagnostic accuracy","score":0.9089999794960022},{"id":"https://openalex.org/keywords/exercise-stress-test","display_name":"exercise stress testing","score":0.9959999918937683},{"id":"https://openalex.org/keywords/stress-echocardiography","display_name":"stress echocardiography","score":0.9990000128746033},{"id":"https://openalex.org/keywords/sensitivity-and-specificity","display_name":"sensitivity and specificity","score":0.8420000076293945},{"id":"https://openalex.org/keywords/diagnostic-test-comparison","display_name":"diagnostic test comparison","score":0.5820000171661377},{"id":"https://openalex.org/keywords/symptomatic-patients","display_name":"symptomatic patients","score":0.5899999737739563},{"id":"https://openalex.org/keywords/myocardial-perfusion-imaging","display_name":"myocardial perfusion imaging","score":0.6769999861717224},{"id":"https://openalex.org/keywords/coronary-angiography","display_name":"coronary angiography","score":0.4000000059604645},{"id":"https://openalex.org/keywords/myocardial-infarction","display_name":"myocardial infarction","score":0.47999998927116394},{"id":"https://openalex.org/keywords/myocardial-ischemia","display_name":"myocardial ischemia","score":0.5479999780654907},{"id":"https://openalex.org/keywords/myocardial-fibrosis","display_name":"myocardial fibrosis","score":0.44699999690055847},{"id":"https://openalex.org/keywords/myocardial-edema","display_name":"myocardial edema","score":0.4300000071525574}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9756268858909607},{"id":"https://openalex.org/C2778213512","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary artery disease","level":2,"score":0.7771530747413635},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6618466377258301},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.6227568984031677},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5931140780448914},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.591363787651062},{"id":"https://openalex.org/C7515471","wikidata":"https://www.wikidata.org/wiki/Q1936882","display_name":"Stress testing (software)","level":2,"score":0.48663458228111267},{"id":"https://openalex.org/C2779902710","wikidata":"https://www.wikidata.org/wiki/Q1130465","display_name":"Scintigraphy","level":2,"score":0.47919902205467224},{"id":"https://openalex.org/C2987145844","wikidata":"https://www.wikidata.org/wiki/Q5038325","display_name":"Cardiac magnetic resonance","level":3,"score":0.454881489276886},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.44323962926864624},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3894095718860626},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/jcm14176238","doi":"https://doi.org/10.3390/jcm14176238","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm14176238","pdf_url":null,"source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},{"id":"pmid:40943997","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40943997","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical medicine","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12429821","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12429821/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Clin Med","raw_type":"Text"},{"id":"pmh:oai:iris.uniroma1.it:11573/1779170","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/11573/1779170","pdf_url":null,"source":{"id":"https://openalex.org/S4377196107","display_name":"IRIS Research product catalog (Sapienza University of Rome)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.3390/jcm14176238","doi":"https://doi.org/10.3390/jcm14176238","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm14176238","pdf_url":null,"source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"},{"id":"https://openalex.org/study-designs/meta-analysis","display_name":"Meta-Analysis"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":210,"referenced_works":["https://openalex.org/W90331983","https://openalex.org/W123245876","https://openalex.org/W139802100","https://openalex.org/W147531007","https://openalex.org/W148499336","https://openalex.org/W203758843","https://openalex.org/W1154990096","https://openalex.org/W1529153994","https://openalex.org/W1531849545","https://openalex.org/W1565485879","https://openalex.org/W1593764750","https://openalex.org/W1599128789","https://openalex.org/W1813550818","https://openalex.org/W1843456789","https://openalex.org/W1902899524","https://openalex.org/W1918354584","https://openalex.org/W1934275081","https://openalex.org/W1964175179","https://openalex.org/W1966265348","https://openalex.org/W1967073664","https://openalex.org/W1967297656","https://openalex.org/W1967736075","https://openalex.org/W1968038365","https://openalex.org/W1968987540","https://openalex.org/W1969215060","https://openalex.org/W1969247312","https://openalex.org/W1970395258","https://openalex.org/W1970406311","https://openalex.org/W1970576900","https://openalex.org/W1971568839","https://openalex.org/W1976145675","https://openalex.org/W1979062511","https://openalex.org/W1979214821","https://openalex.org/W1980281474","https://openalex.org/W1980363246","https://openalex.org/W1980457711","https://openalex.org/W1980805472","https://openalex.org/W1981760045","https://openalex.org/W1985814494","https://openalex.org/W1986417299","https://openalex.org/W1987025760","https://openalex.org/W1988775214","https://openalex.org/W1990558226","https://openalex.org/W1990579664","https://openalex.org/W1991021814","https://openalex.org/W1991514810","https://openalex.org/W1992373635","https://openalex.org/W1994462091","https://openalex.org/W1994570530","https://openalex.org/W1995470381","https://openalex.org/W1996644895","https://openalex.org/W1998957645","https://openalex.org/W2004932115","https://openalex.org/W2005826371","https://openalex.org/W2007232023","https://openalex.org/W2007613238","https://openalex.org/W2007891504","https://openalex.org/W2012715803","https://openalex.org/W2014077895","https://openalex.org/W2015093223","https://openalex.org/W2015439887","https://openalex.org/W2020534468","https://openalex.org/W2026409624","https://openalex.org/W2027405327","https://openalex.org/W2028272680","https://openalex.org/W2029259854","https://openalex.org/W2030506169","https://openalex.org/W2030832929","https://openalex.org/W2034407881","https://openalex.org/W2035710900","https://openalex.org/W2035902805","https://openalex.org/W2036105478","https://openalex.org/W2036270909","https://openalex.org/W2037604424","https://openalex.org/W2040530723","https://openalex.org/W2040580679","https://openalex.org/W2043433198","https://openalex.org/W2047197976","https://openalex.org/W2049135215","https://openalex.org/W2049373023","https://openalex.org/W2051439201","https://openalex.org/W2052826801","https://openalex.org/W2055009083","https://openalex.org/W2057163274","https://openalex.org/W2057355971","https://openalex.org/W2058044929","https://openalex.org/W2063411295","https://openalex.org/W2063993756","https://openalex.org/W2065704743","https://openalex.org/W2066822063","https://openalex.org/W2073521376","https://openalex.org/W2074062131","https://openalex.org/W2077415276","https://openalex.org/W2077752707","https://openalex.org/W2077811172","https://openalex.org/W2079274039","https://openalex.org/W2081931818","https://openalex.org/W2082892925","https://openalex.org/W2084528771","https://openalex.org/W2086655627","https://openalex.org/W2086679255","https://openalex.org/W2087240600","https://openalex.org/W2087343811","https://openalex.org/W2088407333","https://openalex.org/W2089548703","https://openalex.org/W2092511088","https://openalex.org/W2092724951","https://openalex.org/W2094813351","https://openalex.org/W2095437242","https://openalex.org/W2095880462","https://openalex.org/W2097988538","https://openalex.org/W2098758600","https://openalex.org/W2102873241","https://openalex.org/W2103494211","https://openalex.org/W2104168899","https://openalex.org/W2110551678","https://openalex.org/W2112277301","https://openalex.org/W2112470835","https://openalex.org/W2112985617","https://openalex.org/W2115972085","https://openalex.org/W2116308061","https://openalex.org/W2116539669","https://openalex.org/W2119258649","https://openalex.org/W2120521432","https://openalex.org/W2126727011","https://openalex.org/W2130667187","https://openalex.org/W2131974037","https://openalex.org/W2135096715","https://openalex.org/W2135366322","https://openalex.org/W2136145129","https://openalex.org/W2136317102","https://openalex.org/W2140488698","https://openalex.org/W2141050892","https://openalex.org/W2141076662","https://openalex.org/W2141265232","https://openalex.org/W2143719144","https://openalex.org/W2143798499","https://openalex.org/W2144138583","https://openalex.org/W2149240419","https://openalex.org/W2150787354","https://openalex.org/W2150955784","https://openalex.org/W2153742957","https://openalex.org/W2154040430","https://openalex.org/W2154292456","https://openalex.org/W2160853206","https://openalex.org/W2162590591","https://openalex.org/W2169589366","https://openalex.org/W2170297773","https://openalex.org/W2170878708","https://openalex.org/W2194047271","https://openalex.org/W2216368226","https://openalex.org/W2288624792","https://openalex.org/W2319433497","https://openalex.org/W2364441341","https://openalex.org/W2405253784","https://openalex.org/W2406632337","https://openalex.org/W2408880423","https://openalex.org/W2413650547","https://openalex.org/W2436656030","https://openalex.org/W2465046507","https://openalex.org/W2471414352","https://openalex.org/W2477632437","https://openalex.org/W2509098552","https://openalex.org/W2516812301","https://openalex.org/W2520310302","https://openalex.org/W2548871054","https://openalex.org/W2550816536","https://openalex.org/W2589913338","https://openalex.org/W2767542712","https://openalex.org/W2794220386","https://openalex.org/W2800672505","https://openalex.org/W2803333329","https://openalex.org/W2807081930","https://openalex.org/W2885847478","https://openalex.org/W2903987937","https://openalex.org/W2945948377","https://openalex.org/W2951539836","https://openalex.org/W2955457178","https://openalex.org/W2981601139","https://openalex.org/W2985831006","https://openalex.org/W2999813371","https://openalex.org/W3011371150","https://openalex.org/W3011962481","https://openalex.org/W3014963872","https://openalex.org/W3030922600","https://openalex.org/W3039582598","https://openalex.org/W3044853938","https://openalex.org/W3100640177","https://openalex.org/W3130087594","https://openalex.org/W3158128863","https://openalex.org/W3165571492","https://openalex.org/W3191082251","https://openalex.org/W3205797963","https://openalex.org/W4200281827","https://openalex.org/W4245226656","https://openalex.org/W4293102795","https://openalex.org/W4294214983","https://openalex.org/W4294215472","https://openalex.org/W4379601094","https://openalex.org/W4386018756","https://openalex.org/W4386074234","https://openalex.org/W4386303892","https://openalex.org/W4387496698","https://openalex.org/W4390064177","https://openalex.org/W4390661000","https://openalex.org/W4392688299","https://openalex.org/W4393142898","https://openalex.org/W4401915081","https://openalex.org/W4402064302","https://openalex.org/W4408379389"],"related_works":["https://openalex.org/W2056780897","https://openalex.org/W1536111430","https://openalex.org/W7218168515","https://openalex.org/W2047765336","https://openalex.org/W2405340902","https://openalex.org/W3161998406","https://openalex.org/W2362439035","https://openalex.org/W2156497239","https://openalex.org/W2113320661","https://openalex.org/W2022323426"],"abstract_inverted_index":{"Background:":[0],"Since":[1],"the":[2,8,37,65,102,171,259,288,302,308,313,319,330,347,364],"1990s,":[3],"numerous":[4],"investigations":[5],"have":[6,42],"assessed":[7],"diagnostic":[9,67,103,129,314,353],"effectiveness\u2014specifically":[10],"sensitivity,":[11,338],"specificity,":[12],"and":[13,29,46,57,63,91,111,134,151,210,245,305,363],"accuracy\u2014of":[14],"exercise":[15],"stress":[16,19,22,30,108,112,207,219,327,333],"testing":[17],"(EST),":[18],"echocardiography":[20],"(SE),":[21],"myocardial":[23,109,208,334],"single-photon":[24],"emission":[25],"computed":[26],"tomography":[27],"(SPECT),":[28],"cardiac":[31],"magnetic":[32],"resonance":[33],"imaging":[34],"(CMR).":[35],"However,":[36],"outcomes":[38],"of":[39,69,85,93,105,144,157,290,307,366],"these":[40,70],"studies":[41,100,292],"often":[43],"been":[44],"inconsistent":[45],"inconclusive.":[47],"To":[48],"provide":[49],"a":[50],"clearer":[51],"comparison,":[52],"we":[53],"conducted":[54,96],"systematic":[55],"reviews":[56],"meta-analyses":[58],"aimed":[59],"at":[60],"quantitatively":[61],"evaluating":[62,101],"comparing":[64],"aggregated":[66],"performance":[68],"four":[71],"commonly":[72],"used":[73],"techniques":[74],"for":[75,177,188,197,206,218,282,322],"detecting":[76,323],"coronary":[77],"artery":[78],"disease":[79],"(CAD).":[80],"Methods:":[81],"A":[82,155],"comprehensive":[83],"search":[84],"PubMed,":[86],"Scopus,":[87],"Embase,":[88],"Cochrane":[89],"Library,":[90],"Web":[92],"Science":[94],"was":[95,125,256,341],"to":[97,126,269,287],"identify":[98],"cohort":[99],"accuracy":[104,321,354],"EST,":[106,189],"SE,":[107,198],"SPECT,":[110,209],"CMR":[113,328],"in":[114,142],"symptomatic":[115,162],"patients":[116],"with":[117,164,356],"suspected":[118,166],"or":[119,167],"confirmed":[120],"CAD.":[121],"The":[122,174],"main":[123],"goal":[124],"compare":[127],"their":[128],"value":[130],"by":[131,263],"pooling":[132],"sensitivity":[133,299],"specificity":[135,340],"results.":[136,296],"Each":[137],"study\u2019s":[138],"data":[139],"were":[140,180,223],"extracted":[141],"terms":[143],"true":[145,149],"positives,":[146,148],"false":[147,152],"negatives,":[150],"negatives.":[153],"Results:":[154],"total":[156],"104":[158],"studies,":[159,260],"comprising":[160],"16,824":[161],"individuals":[163],"either":[165],"known":[168],"CAD,":[169,325],"met":[170],"inclusion":[172],"criteria.":[173],"pooled":[175,309],"sensitivities":[176],"CAD":[178],"detection":[179],"0.66":[181],"(95%":[182,191,200,212,225,232,239,247],"CI:":[183,192,201,213,226,233,240,248],"0.59\u20130.72,":[184],"p":[185,194,203,215,228,235,242,250],"<":[186,195,204,216,229,236,243,251,280],"0.001)":[187,196,205,217],"0.81":[190],"0.79\u20130.83,":[193],"0.82":[199],"0.78\u20130.85,":[202],"0.83":[211],"0.81\u20130.85,":[214],"CMR.":[220],"Corresponding":[221],"specificities":[222],"0.61":[224],"0.55\u20130.67,":[227],"0.001),":[230,237,244,252],"0.85":[231],"0.82\u20130.87,":[234],"0.74":[238],"0.70\u20130.78,":[241],"0.89":[246],"0.86\u20130.92,":[249],"respectively.":[253],"Considerable":[254],"heterogeneity":[255],"observed":[257],"across":[258],"as":[261,346,359],"reflected":[262],"I2":[264],"values":[265],"ranging":[266],"from":[267],"82.5%":[268],"92.5%.":[270],"Egger\u2019s":[271],"generalized":[272],"test":[273],"revealed":[274],"statistically":[275],"significant":[276],"publication":[277],"bias":[278],"(p":[279],"0.05":[281],"all":[283],"methods),":[284],"likely":[285],"due":[286],"influence":[289],"smaller":[291],"reporting":[293],"more":[294],"favorable":[295],"Despite":[297],"this,":[298],"analyses":[300],"supported":[301],"overall":[303],"robustness":[304],"reliability":[306],"findings.":[310],"Conclusions:":[311],"Among":[312],"tools":[315],"assessed,":[316],"EST":[317],"demonstrated":[318],"lowest":[320],"obstructive":[324],"whereas":[326],"exhibited":[329],"highest.":[331],"Although":[332],"SPECT":[335],"showed":[336],"strong":[337],"its":[339],"comparatively":[342],"limited.":[343],"SE":[344],"emerged":[345],"most":[348],"balanced":[349],"option,":[350],"offering":[351],"good":[352],"combined":[355],"advantages":[357],"such":[358],"broad":[360],"availability,":[361],"cost-effectiveness,":[362],"absence":[365],"ionizing":[367],"radiation.":[368]},"counts_by_year":[{"year":2026,"cited_by_count":20},{"year":2025,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2025-10-10T00:00:00"}
