{"id":"https://openalex.org/W4413991663","doi":"https://doi.org/10.1093/schizbullopen/sgaf019","title":"Obstacles, Opportunities, and Ethical Considerations for Genomic Investigations of Individuals Continuously Hospitalized with Treatment-resistant Schizophrenia","display_name":"Obstacles, Opportunities, and Ethical Considerations for Genomic Investigations of Individuals Continuously Hospitalized with Treatment-resistant Schizophrenia","publication_year":2025,"publication_date":"2025-01-01","ids":{"openalex":"https://openalex.org/W4413991663","doi":"https://doi.org/10.1093/schizbullopen/sgaf019","pmid":"https://pubmed.ncbi.nlm.nih.gov/41050266"},"language":"en","primary_location":{"id":"doi:10.1093/schizbullopen/sgaf019","doi":"https://doi.org/10.1093/schizbullopen/sgaf019","is_oa":true,"landing_page_url":"https://doi.org/10.1093/schizbullopen/sgaf019","pdf_url":"https://academic.oup.com/schizbullopen/advance-article-pdf/doi/10.1093/schizbullopen/sgaf019/64206410/sgaf019.pdf","source":{"id":"https://openalex.org/S4210209414","display_name":"Schizophrenia Bulletin Open","issn_l":"2632-7899","issn":["2632-7899"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Schizophrenia Bulletin Open","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/schizbullopen/advance-article-pdf/doi/10.1093/schizbullopen/sgaf019/64206410/sgaf019.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015986391","display_name":"Richard C. Josiassen","orcid":"https://orcid.org/0000-0002-2572-975X","observed_orcids":["https://orcid.org/0000-0002-2572-975X"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Richard C Josiassen","raw_affiliation_strings":["Translational Neuroscience , Philadelphia, PA 19119 ,","Translational Neuroscience , Philadelphia, PA ,","Translational Neuroscience, Philadelphia, PA 19119, United States"],"raw_orcid":"https://orcid.org/0000-0002-2572-975X","affiliations":[{"raw_affiliation_string":"Translational Neuroscience , Philadelphia, PA 19119 ,","institution_ids":[]},{"raw_affiliation_string":"Translational Neuroscience , Philadelphia, PA ,","institution_ids":[]},{"raw_affiliation_string":"Translational Neuroscience, Philadelphia, PA 19119, United States","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083179769","display_name":"Rose Mary Xavier","orcid":"https://orcid.org/0000-0003-0771-3049","observed_orcids":["https://orcid.org/0000-0003-0771-3049"]},"institutions":[{"id":"https://openalex.org/I919571938","display_name":"The University of Texas Health Science Center at Houston","ror":"https://ror.org/03gds6c39","country_code":"US","type":"education","lineage":["https://openalex.org/I919571938"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rose Mary Xavier","raw_affiliation_strings":["Department of Research, UTHealth Houston Cizik School of Nursing , Houston, TX 77030 ,","Department of Research, UTHealth Houston Cizik School of Nursing, Houston, TX 77030, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Research, UTHealth Houston Cizik School of Nursing , Houston, TX 77030 ,","institution_ids":["https://openalex.org/I919571938"]},{"raw_affiliation_string":"Department of Research, UTHealth Houston Cizik School of Nursing, Houston, TX 77030, United States","institution_ids":["https://openalex.org/I919571938"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045839192","display_name":"Tyler E Dietterich","orcid":"https://orcid.org/0000-0003-1909-0010","observed_orcids":["https://orcid.org/0000-0003-1909-0010"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tyler E Dietterich","raw_affiliation_strings":["Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior , University of California, Los Angeles, Los Angeles, CA 90024 ,","Translational Neuroscience , Philadelphia, PA 19119 ,","Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA 90024, United States","Translational Neuroscience , Philadelphia, PA ,","Translational Neuroscience, Philadelphia, PA 19119, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior , University of California, Los Angeles, Los Angeles, CA 90024 ,","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"Translational Neuroscience , Philadelphia, PA 19119 ,","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA 90024, United States","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"Translational Neuroscience , Philadelphia, PA ,","institution_ids":[]},{"raw_affiliation_string":"Translational Neuroscience, Philadelphia, PA 19119, United States","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021211935","display_name":"Matthew K. Harner","orcid":"https://orcid.org/0000-0002-1241-4855","observed_orcids":["https://orcid.org/0000-0002-1241-4855"]},"institutions":[{"id":"https://openalex.org/I102322142","display_name":"Rutgers, The State University of New Jersey","ror":"https://ror.org/05vt9qd57","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew K Harner","raw_affiliation_strings":["Center for Advanced Biotechnology and Medicine, Rutgers University , Piscataway, NJ 08854 ,","Department of Psychiatry, Rutgers University , New Brunswick, NJ 08901 ,","Translational Neuroscience , Philadelphia, PA 19119 ,","Department of Psychiatry, Rutgers University, New Brunswick, NJ 08901, United States","Translational Neuroscience , Philadelphia, PA ,","Translational Neuroscience, Philadelphia, PA 19119, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Advanced Biotechnology and Medicine, Rutgers University , Piscataway, NJ 08854 ,","institution_ids":["https://openalex.org/I102322142"]},{"raw_affiliation_string":"Department of Psychiatry, Rutgers University , New Brunswick, NJ 08901 ,","institution_ids":["https://openalex.org/I102322142"]},{"raw_affiliation_string":"Translational Neuroscience , Philadelphia, PA 19119 ,","institution_ids":[]},{"raw_affiliation_string":"Department of Psychiatry, Rutgers University, New Brunswick, NJ 08901, United States","institution_ids":["https://openalex.org/I102322142"]},{"raw_affiliation_string":"Translational Neuroscience , Philadelphia, PA ,","institution_ids":[]},{"raw_affiliation_string":"Translational Neuroscience, Philadelphia, PA 19119, United States","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059490439","display_name":"Dawn M. Filmyer","orcid":"https://orcid.org/0000-0002-6991-3903","observed_orcids":["https://orcid.org/0000-0002-6991-3903"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dawn M Filmyer","raw_affiliation_strings":["Translational Neuroscience , Philadelphia, PA 19119 ,","Translational Neuroscience , Philadelphia, PA ,","Translational Neuroscience, Philadelphia, PA 19119, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Translational Neuroscience , Philadelphia, PA 19119 ,","institution_ids":[]},{"raw_affiliation_string":"Translational Neuroscience , Philadelphia, PA ,","institution_ids":[]},{"raw_affiliation_string":"Translational Neuroscience, Philadelphia, PA 19119, United States","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5119540714","display_name":"Cassie Houpt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cassie Houpt","raw_affiliation_strings":["Department of Medical Ethics and Health Policy, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA 19104, United States","Department of Medical Ethics and Health Policy, University of Pennsylvania , Philadelphia, PA, USA and Postdoctoral Fellow in the Ethical, Legal, and Social Implications of Human Genetics and Genomics, University of Pennsylvania, Philadelphia, PA \u00a0"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Ethics and Health Policy, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA 19104, United States","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Department of Medical Ethics and Health Policy, University of Pennsylvania , Philadelphia, PA, USA and Postdoctoral Fellow in the Ethical, Legal, and Social Implications of Human Genetics and Genomics, University of Pennsylvania, Philadelphia, PA \u00a0","institution_ids":["https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007466739","display_name":"Maya L. Lichtenstein","orcid":"https://orcid.org/0000-0001-6270-575X","observed_orcids":["https://orcid.org/0000-0001-6270-575X"]},"institutions":[{"id":"https://openalex.org/I54713919","display_name":"Geisinger Health System","ror":"https://ror.org/02qdbgx97","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I54713919"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maya L Lichtenstein","raw_affiliation_strings":["Department of Neurology, Geisinger Health System, Wilkes Barre , PA 18765 ,","Department of Neurology, Geisinger Health System, Wilkes Barre, PA 18765, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Geisinger Health System, Wilkes Barre , PA 18765 ,","institution_ids":["https://openalex.org/I54713919"]},{"raw_affiliation_string":"Department of Neurology, Geisinger Health System, Wilkes Barre, PA 18765, United States","institution_ids":["https://openalex.org/I54713919"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064511256","display_name":"Martilias S. Farrell","orcid":"https://orcid.org/0000-0002-9520-6209","observed_orcids":["https://orcid.org/0000-0002-9520-6209"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Martilias Farrell","raw_affiliation_strings":["Department of Natural and Applied Science, Cheyney University , Philadelphia, PA 19319,","Department of Natural and Applied Science, Cheyney University, Philadelphia, PA 19319, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Natural and Applied Science, Cheyney University , Philadelphia, PA 19319,","institution_ids":[]},{"raw_affiliation_string":"Department of Natural and Applied Science, Cheyney University, Philadelphia, PA 19319, United States","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034062371","display_name":"Rita A. Shaughnessy","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rita A Shaughnessy","raw_affiliation_strings":["Translational Neuroscience , Philadelphia, PA 19119 ,","Translational Neuroscience , Philadelphia, PA ,","Translational Neuroscience, Philadelphia, PA 19119, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Translational Neuroscience , Philadelphia, PA 19119 ,","institution_ids":[]},{"raw_affiliation_string":"Translational Neuroscience , Philadelphia, PA ,","institution_ids":[]},{"raw_affiliation_string":"Translational Neuroscience, Philadelphia, PA 19119, United States","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024724548","display_name":"Gabriel L\u00e1zaro\u2010Mu\u00f1oz","orcid":"https://orcid.org/0000-0003-1933-9453","observed_orcids":["https://orcid.org/0000-0003-1933-9453"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gabriel Lazaro-Munoz","raw_affiliation_strings":["Center for Bioethics, Harvard Medical School , Boston, MA 02115 ,","Departments of Psychiatry and Neurosurgery, Massachusetts General Hospital , Boston, MA 02114 ,","Center for Bioethics, Harvard Medical School , Boston, MA ,","Center for Bioethics, Harvard Medical School, Boston, MA 02115, United States","Departments of Psychiatry and Neurosurgery, Massachusetts General Hospital, Boston, MA 02114, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Bioethics, Harvard Medical School , Boston, MA 02115 ,","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Departments of Psychiatry and Neurosurgery, Massachusetts General Hospital , Boston, MA 02114 ,","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Center for Bioethics, Harvard Medical School , Boston, MA ,","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Center for Bioethics, Harvard Medical School, Boston, MA 02115, United States","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Departments of Psychiatry and Neurosurgery, Massachusetts General Hospital, Boston, MA 02114, United States","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028470777","display_name":"Jonathan S. Berg","orcid":"https://orcid.org/0000-0003-2360-2664","observed_orcids":["https://orcid.org/0000-0003-2360-2664"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonathan S Berg","raw_affiliation_strings":["Department of Genetics, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599 ,","Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599 ,","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061802355","display_name":"Patrick F. Sullivan","orcid":"https://orcid.org/0000-0002-6619-873X","observed_orcids":["https://orcid.org/0000-0002-6619-873X"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE","US"],"is_corresponding":false,"raw_author_name":"Patrick F Sullivan","raw_affiliation_strings":["Department of Genetics, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599 ,","Department of Medical Epidemiology and Biostatistics, Karolinska Institutet , Stockholm ,","Department of Psychiatry, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599 ,","Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden","Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599 ,","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"Department of Medical Epidemiology and Biostatistics, Karolinska Institutet , Stockholm ,","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Department of Psychiatry, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599 ,","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States","institution_ids":["https://openalex.org/I114027177"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5015986391"],"corresponding_institution_ids":[],"apc_list":{"value":3662,"currency":"USD","value_usd":3662},"apc_paid":{"value":3662,"currency":"USD","value_usd":3662},"fwci":1.6453,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.84515375,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":97},"biblio":{"volume":"6","issue":"1","first_page":"sgaf019","last_page":"sgaf019"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10582","display_name":"Ethics in Clinical Research","score":0.8823000192642212,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10582","display_name":"Ethics in Clinical Research","score":0.8823000192642212,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11678","display_name":"Healthcare Decision-Making and Restraints","score":0.11209999769926071,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/treatment-resistant-schizophrenia","display_name":"treatment-resistant schizophrenia","score":0.9950000047683716},{"id":"https://openalex.org/keywords/genomic-research","display_name":"genomic research","score":0.6060000061988831},{"id":"https://openalex.org/keywords/research-ethics","display_name":"research ethics","score":0.7870000004768372},{"id":"https://openalex.org/keywords/informed-consent","display_name":"informed consent","score":0.9570000171661377},{"id":"https://openalex.org/keywords/decision-making-capacity","display_name":"decision-making capacity","score":0.8610000014305115},{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"cognitive impairment","score":0.7979999780654907},{"id":"https://openalex.org/keywords/involuntary-psychiatric-commitment","display_name":"involuntary psychiatric commitment","score":0.8379999995231628},{"id":"https://openalex.org/keywords/state-psychiatric-hospitals","display_name":"state psychiatric hospitals","score":0.7139999866485596},{"id":"https://openalex.org/keywords/research-exclusion","display_name":"research exclusion","score":0.4790000021457672},{"id":"https://openalex.org/keywords/health-care-disparities","display_name":"health care disparities","score":0.8009999990463257},{"id":"https://openalex.org/keywords/community-engagement","display_name":"community participation","score":0.8489999771118164},{"id":"https://openalex.org/keywords/confidentiality","display_name":"confidentiality","score":0.4860000014305115}],"concepts":[{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.722511351108551},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3886690139770508},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.36184975504875183},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.35336434841156006},{"id":"https://openalex.org/C55587333","wikidata":"https://www.wikidata.org/wiki/Q1133029","display_name":"Engineering ethics","level":1,"score":0.352169394493103},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.1384846568107605}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.1093/schizbullopen/sgaf019","doi":"https://doi.org/10.1093/schizbullopen/sgaf019","is_oa":true,"landing_page_url":"https://doi.org/10.1093/schizbullopen/sgaf019","pdf_url":"https://academic.oup.com/schizbullopen/advance-article-pdf/doi/10.1093/schizbullopen/sgaf019/64206410/sgaf019.pdf","source":{"id":"https://openalex.org/S4210209414","display_name":"Schizophrenia Bulletin Open","issn_l":"2632-7899","issn":["2632-7899"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Schizophrenia Bulletin Open","raw_type":"journal-article"},{"id":"pmid:41050266","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41050266","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Schizophrenia bulletin open","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:11305655","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12496010","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:cdr.lib.unc.edu:qz20t7879","doi":null,"is_oa":true,"landing_page_url":"https://doi.org/10.17615/z3gk-xh31","pdf_url":null,"source":{"id":"https://openalex.org/S4306401075","display_name":"Carolina Digital Repository (University of North Carolina at Chapel Hill)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114027177","host_organization_name":"University of North Carolina at Chapel Hill","host_organization_lineage":["https://openalex.org/I114027177"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Schizophrenia Bulletin Open, 6(1)","raw_type":"Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12496010","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12496010/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Schizophr Bull Open","raw_type":"Text"},{"id":"doi:10.17615/z3gk-xh31","doi":"https://doi.org/10.17615/z3gk-xh31","is_oa":true,"landing_page_url":"https://doi.org/10.17615/z3gk-xh31","pdf_url":null,"source":{"id":"https://openalex.org/S7407051488","display_name":"UNC Libraries","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.1093/schizbullopen/sgaf019","doi":"https://doi.org/10.1093/schizbullopen/sgaf019","is_oa":true,"landing_page_url":"https://doi.org/10.1093/schizbullopen/sgaf019","pdf_url":"https://academic.oup.com/schizbullopen/advance-article-pdf/doi/10.1093/schizbullopen/sgaf019/64206410/sgaf019.pdf","source":{"id":"https://openalex.org/S4210209414","display_name":"Schizophrenia Bulletin Open","issn_l":"2632-7899","issn":["2632-7899"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Schizophrenia Bulletin Open","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"},{"display_name":"Reduced inequalities","score":0.4074000120162964,"id":"https://metadata.un.org/sdg/10"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2878046959","display_name":null,"funder_award_id":"K01MH108894","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G718746359","display_name":null,"funder_award_id":"K99HG008689","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G8089189751","display_name":null,"funder_award_id":"R01 MH110427","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F259686030","display_name":"Support for Pioneering Research Initiated by the Next Generation","ror":null},{"id":"https://openalex.org/F4320306137","display_name":"Bill and Melinda Gates Foundation","ror":"https://ror.org/0456r8d26"},{"id":"https://openalex.org/F4320306219","display_name":"Alzheimer's Association","ror":"https://ror.org/0375f4d26"},{"id":"https://openalex.org/F4320306239","display_name":"Conquer Cancer Foundation","ror":"https://ror.org/027327e78"},{"id":"https://openalex.org/F4320306260","display_name":"Breast Cancer Research Foundation","ror":"https://ror.org/0348ff195"},{"id":"https://openalex.org/F4320307105","display_name":"Amgen","ror":"https://ror.org/03g03ge92"},{"id":"https://openalex.org/F4320308192","display_name":"Chesapeake Bay Program","ror":"https://ror.org/04x4haa49"},{"id":"https://openalex.org/F4320308519","display_name":"American College of Cardiology Foundation","ror":"https://ror.org/03pgm1r86"},{"id":"https://openalex.org/F4320309944","display_name":"Cure Alzheimer's Fund","ror":"https://ror.org/05ewr7t48"},{"id":"https://openalex.org/F4320310176","display_name":"University of Wisconsin Carbone Cancer Center","ror":"https://ror.org/02mqqhj42"},{"id":"https://openalex.org/F4320311600","display_name":"Regeneron Pharmaceuticals","ror":"https://ror.org/02f51rf24"},{"id":"https://openalex.org/F4320312140","display_name":"Exelixis","ror":"https://ror.org/01e3jga91"},{"id":"https://openalex.org/F4320313999","display_name":"Hospital for Special Surgery","ror":"https://ror.org/03zjqec80"},{"id":"https://openalex.org/F4320315062","display_name":"Ministerio de Ciencia, Innovaci\u00f3n y Universidades","ror":null},{"id":"https://openalex.org/F4320315402","display_name":"Arrowhead Pharmaceuticals","ror":"https://ror.org/00919v790"},{"id":"https://openalex.org/F4320316262","display_name":"Duke-NUS Medical School","ror":"https://ror.org/02j1m6098"},{"id":"https://openalex.org/F4320317015","display_name":"Alzheimer's Society","ror":"https://ror.org/0472gwq90"},{"id":"https://openalex.org/F4320318031","display_name":"Japanese Foundation for Research and Promotion of Endoscopy","ror":"https://ror.org/05mt01203"},{"id":"https://openalex.org/F4320318497","display_name":"Heidi Seiler-Stiftung","ror":"https://ror.org/03v6nbf10"},{"id":"https://openalex.org/F4320319455","display_name":"Tamura Science and Technology Foundation","ror":"https://ror.org/01ayhsk19"},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320320320","display_name":"Rosetrees Trust","ror":"https://ror.org/04e3zg361"},{"id":"https://openalex.org/F4320320671","display_name":"National Research Foundation","ror":"https://ror.org/05s0g1g46"},{"id":"https://openalex.org/F4320320719","display_name":"Department of Science and Technology, Ministry of Science and Technology, India","ror":"https://ror.org/0101xrq71"},{"id":"https://openalex.org/F4320320720","display_name":"Indian Council of Medical Research","ror":"https://ror.org/0492wrx28"},{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"},{"id":"https://openalex.org/F4320320912","display_name":"Ministry of Education, Culture, Sports, Science and Technology","ror":"https://ror.org/048rj2z13"},{"id":"https://openalex.org/F4320320924","display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","ror":"https://ror.org/00yjd3n13"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321114","display_name":"Bundesministerium f\u00fcr Bildung und Forschung","ror":"https://ror.org/04pz7b180"},{"id":"https://openalex.org/F4320321505","display_name":"Generalitat de Catalunya","ror":"https://ror.org/01bg62x04"},{"id":"https://openalex.org/F4320321781","display_name":"Ministero della Salute","ror":"https://ror.org/00789fa95"},{"id":"https://openalex.org/F4320321800","display_name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","ror":"https://ror.org/04jsz6e67"},{"id":"https://openalex.org/F4320321883","display_name":"Huazhong University of Science and Technology","ror":"https://ror.org/00p991c53"},{"id":"https://openalex.org/F4320321955","display_name":"Henan University of Technology","ror":"https://ror.org/05sbgwt55"},{"id":"https://openalex.org/F4320322107","display_name":"Korea Health Industry Development Institute","ror":"https://ror.org/00fdzyk40"},{"id":"https://openalex.org/F4320322363","display_name":"Ligue Contre le Cancer","ror":"https://ror.org/00rkrv905"},{"id":"https://openalex.org/F4320323128","display_name":"Jawaharlal Nehru Centre for Advanced Scientific Research","ror":"https://ror.org/0538gdx71"},{"id":"https://openalex.org/F4320323309","display_name":"Universidad de Huelva","ror":"https://ror.org/03a1kt624"},{"id":"https://openalex.org/F4320323485","display_name":"China Academy of Chinese Medical Sciences","ror":"https://ror.org/042pgcv68"},{"id":"https://openalex.org/F4320323555","display_name":"Deutsche Herzstiftung","ror":"https://ror.org/02hq6wv21"},{"id":"https://openalex.org/F4320324496","display_name":"Universidad Rey Juan Carlos","ror":"https://ror.org/01v5cv687"},{"id":"https://openalex.org/F4320324805","display_name":"Chongqing Municipal Education Commission","ror":"https://ror.org/031nm5713"},{"id":"https://openalex.org/F4320324826","display_name":"Institut Gustave-Roussy","ror":"https://ror.org/0321g0743"},{"id":"https://openalex.org/F4320325276","display_name":"Iketani Science and Technology Foundation","ror":"https://ror.org/0382jhd52"},{"id":"https://openalex.org/F4320325291","display_name":"Tokuyama Science Foundation","ror":"https://ror.org/04zj4k586"},{"id":"https://openalex.org/F4320325294","display_name":"Yazaki Memorial Foundation for Science and Technology","ror":"https://ror.org/04dgpsg75"},{"id":"https://openalex.org/F4320326375","display_name":"Hellenic Society of Medical Oncology","ror":"https://ror.org/02ar9bs92"},{"id":"https://openalex.org/F4320327918","display_name":"H. Lundbeck A/S","ror":"https://ror.org/0564cd633"},{"id":"https://openalex.org/F4320328359","display_name":"Ministry of Science and ICT, South Korea","ror":"https://ror.org/01wpjm123"},{"id":"https://openalex.org/F4320329861","display_name":"Natural Science Foundation of Sichuan Province","ror":null},{"id":"https://openalex.org/F4320332177","display_name":"Agency for Healthcare Research and Quality","ror":"https://ror.org/03jmfdf59"},{"id":"https://openalex.org/F4320333003","display_name":"Chugai Pharmaceutical","ror":"https://ror.org/01vepzj85"},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"},{"id":"https://openalex.org/F4320334771","display_name":"Science and Engineering Research Board","ror":"https://ror.org/03ffdsr55"},{"id":"https://openalex.org/F4320334785","display_name":"Health Services and Delivery Research Programme","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320335598","display_name":"Agencia Estatal de Investigaci\u00f3n","ror":"https://ror.org/003x0zc53"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"},{"id":"https://openalex.org/F8269005443","display_name":"NCCR Catalysis","ror":"https://ror.org/03qf6ek79"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4413991663.pdf","grobid_xml":"https://content.openalex.org/works/W4413991663.grobid-xml"},"referenced_works_count":90,"referenced_works":["https://openalex.org/W132470944","https://openalex.org/W1491675266","https://openalex.org/W1493671385","https://openalex.org/W1561073844","https://openalex.org/W1595379164","https://openalex.org/W1900361016","https://openalex.org/W1969178175","https://openalex.org/W1969311097","https://openalex.org/W1978868050","https://openalex.org/W1982993637","https://openalex.org/W1983743419","https://openalex.org/W1986391597","https://openalex.org/W1989405621","https://openalex.org/W1994904405","https://openalex.org/W1996068508","https://openalex.org/W1997597399","https://openalex.org/W2001027823","https://openalex.org/W2001157702","https://openalex.org/W2008270161","https://openalex.org/W2008316348","https://openalex.org/W2010510096","https://openalex.org/W2013079915","https://openalex.org/W2013173881","https://openalex.org/W2018914271","https://openalex.org/W2022496356","https://openalex.org/W2023168054","https://openalex.org/W2026138453","https://openalex.org/W2036480935","https://openalex.org/W2039628501","https://openalex.org/W2040939895","https://openalex.org/W2047246726","https://openalex.org/W2047285582","https://openalex.org/W2056470410","https://openalex.org/W2063485517","https://openalex.org/W2068597553","https://openalex.org/W2081911459","https://openalex.org/W2096789339","https://openalex.org/W2097614477","https://openalex.org/W2101603047","https://openalex.org/W2104504176","https://openalex.org/W2110293983","https://openalex.org/W2112364118","https://openalex.org/W2116938071","https://openalex.org/W2118424683","https://openalex.org/W2119768752","https://openalex.org/W2120040647","https://openalex.org/W2121579343","https://openalex.org/W2123351707","https://openalex.org/W2123423334","https://openalex.org/W2127025881","https://openalex.org/W2134303994","https://openalex.org/W2134459796","https://openalex.org/W2140165667","https://openalex.org/W2140606211","https://openalex.org/W2142670205","https://openalex.org/W2144534760","https://openalex.org/W2147430717","https://openalex.org/W2150060517","https://openalex.org/W2152528318","https://openalex.org/W2157242561","https://openalex.org/W2168085741","https://openalex.org/W2168851930","https://openalex.org/W2204104926","https://openalex.org/W2594904649","https://openalex.org/W2596755633","https://openalex.org/W2620226670","https://openalex.org/W2799986539","https://openalex.org/W2808969407","https://openalex.org/W2902078276","https://openalex.org/W2911210644","https://openalex.org/W2951317142","https://openalex.org/W2969585356","https://openalex.org/W2987889701","https://openalex.org/W3004307487","https://openalex.org/W3027266500","https://openalex.org/W3086488182","https://openalex.org/W3120213857","https://openalex.org/W3197418950","https://openalex.org/W4200501170","https://openalex.org/W4205105460","https://openalex.org/W4210419267","https://openalex.org/W4309440999","https://openalex.org/W4310490795","https://openalex.org/W4327759202","https://openalex.org/W4387421910","https://openalex.org/W4388066189","https://openalex.org/W4392373093","https://openalex.org/W4392953386","https://openalex.org/W4406234441","https://openalex.org/W4412822153"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W3031052312","https://openalex.org/W4389568370","https://openalex.org/W3032375762","https://openalex.org/W1995515455","https://openalex.org/W2080531066","https://openalex.org/W3108674512","https://openalex.org/W1506200166"],"abstract_inverted_index":{"Background":[0],"and":[1,55,62,94,113,142,154,165],"Hypothesis:":[2],"found":[3],"within":[4],"this":[5,41],"heterogeneous":[6],"population.":[7],"But":[8],"individuals":[9,77,112,177,188],"committed":[10,176],"to":[11,30,51,137,192],"state":[12],"psychiatric":[13],"institutions":[14],"have":[15,145],"been":[16,146],"routinely":[17],"excluded":[18],"from":[19,121],"research":[20,151,195],"because":[21],"of":[22,59,71,102,109,131,163],"concerns":[23],"that":[24,46,125,172,200],"they":[25],"may":[26],"not":[27],"be":[28,179],"able":[29],"understand":[31],"or":[32],"provide":[33,98],"adequately":[34],"informed":[35,159],"consent.":[36],"While":[37],"reasonable,":[38],"we":[39,97,116],"believe":[40],"approach":[42],"has":[43,90,201],"enabled":[44],"policies":[45],"support":[47],"implicit":[48],"bias,":[49],"contribute":[50],"health":[52],"care":[53],"disparities,":[54],"limit":[56],"our":[57,103],"knowledge":[58],"disease":[60],"mechanisms":[61],"treatment.":[63],"Study":[64,118],"Design:":[65],"This":[66],"article":[67],"provides":[68],"brief":[69],"reviews":[70],"(1)":[72,149],"ethical":[73,185],"considerations":[74,144],"when":[75],"recruiting":[76],"with":[78],"severely":[79],"treatment-resistant":[80],"psychotic":[81],"symptoms":[82],"for":[83,194],"research,":[84],"(2)":[85,156],"the":[86,114,134,190,197],"impact":[87],"their":[88,204],"condition":[89],"on":[91],"decision-making":[92],"capacity,":[93,164],"finally":[95],"(3)":[96,158],"a":[99,106],"first-hand":[100],"narrative":[101],"experience":[104,170],"conducting":[105],"genomic":[107],"study":[108],"involuntarily":[110,175],"hospitalized":[111],"opportunities/obstacles":[115],"encountered.":[117],"Results:":[119],"Evidence":[120],"published":[122],"literature":[123],"shows":[124],"cognitive":[126],"impairment,":[127],"rather":[128],"than":[129],"severity":[130],"psychopathology,":[132],"is":[133,208],"greatest":[135],"threat":[136],"decisional":[138],"capacity.":[139],"Ethical":[140],"safeguards":[141],"practical":[143],"developed,":[147],"including":[148],"institutional/local":[150],"committee":[152],"review":[153],"approval,":[155],"confidentiality,":[157],"consent,":[160],"(4)":[161],"assessment":[162],"(5)":[166],"community":[167],"engagement.":[168],"Our":[169],"demonstrates":[171],"carefully":[173],"selected":[174],"can":[178],"included":[180],"in":[181],"research.":[182],"Conclusions:":[183],"With":[184],"safeguards,":[186],"these":[187],"deserve":[189],"opportunity":[191],"volunteer":[193],"regarding":[196],"mental":[198],"illness":[199],"profoundly":[202],"shaped":[203],"lives-to":[205],"do":[206],"otherwise":[207],"discriminatory.":[209]},"counts_by_year":[{"year":2026,"cited_by_count":2}],"updated_date":"2026-10-15T10:00:46.086208","created_date":"2025-10-10T00:00:00"}