{"id":"https://openalex.org/W4413801596","doi":"https://doi.org/10.1002/cnr2.70333","title":"Elevated Risk of HPV \u2010Associated Oropharyngeal Cancers in Husbands of Women With Anogenital Cancer","display_name":"Elevated Risk of HPV \u2010Associated Oropharyngeal Cancers in Husbands of Women With Anogenital Cancer","publication_year":2025,"publication_date":"2025-08-28","ids":{"openalex":"https://openalex.org/W4413801596","doi":"https://doi.org/10.1002/cnr2.70333","pmid":"https://pubmed.ncbi.nlm.nih.gov/40877205"},"language":"en","primary_location":{"id":"doi:10.1002/cnr2.70333","doi":"https://doi.org/10.1002/cnr2.70333","is_oa":true,"landing_page_url":"https://doi.org/10.1002/cnr2.70333","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cnr2.70333","source":{"id":"https://openalex.org/S4210241191","display_name":"Cancer Reports","issn_l":"2573-8348","issn":["2573-8348"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Reports","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cnr2.70333","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103113089","display_name":"Tuomas Lehtinen","orcid":"https://orcid.org/0000-0003-1460-422X","observed_orcids":["https://orcid.org/0000-0003-1460-422X"]},"institutions":[{"id":"https://openalex.org/I166825849","display_name":"Tampere University","ror":"https://ror.org/033003e23","country_code":"FI","type":"education","lineage":["https://openalex.org/I166825849"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Tuomas Lehtinen","raw_affiliation_strings":["FICAN\u2010Mid Tampere University  Tampere Finland","FICAN-Mid, Tampere University, Tampere, Finland"],"raw_orcid":"https://orcid.org/0000-0003-1460-422X","affiliations":[{"raw_affiliation_string":"FICAN\u2010Mid Tampere University  Tampere Finland","institution_ids":["https://openalex.org/I166825849"]},{"raw_affiliation_string":"FICAN-Mid, Tampere University, Tampere, Finland","institution_ids":["https://openalex.org/I166825849"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079766176","display_name":"Luayo Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17937529","display_name":"German Cancer Research Center","ror":"https://ror.org/04cdgtt98","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I17937529"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Luayo Zhang","raw_affiliation_strings":["Molecular Genetic Epidemiology Division Deutsches Krebsforschungszentrum (DKFZ)  Heidelberg Germany","Molecular Genetic Epidemiology Division, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Genetic Epidemiology Division Deutsches Krebsforschungszentrum (DKFZ)  Heidelberg Germany","institution_ids":["https://openalex.org/I17937529"]},{"raw_affiliation_string":"Molecular Genetic Epidemiology Division, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany","institution_ids":["https://openalex.org/I17937529"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087981165","display_name":"Kristina Sundquist","orcid":"https://orcid.org/0000-0001-8031-279X","observed_orcids":["https://orcid.org/0000-0001-8031-279X"]},"institutions":[{"id":"https://openalex.org/I169016828","display_name":"Shimane University","ror":"https://ror.org/01jaaym28","country_code":"JP","type":"education","lineage":["https://openalex.org/I169016828"]},{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I3129591023","display_name":"University of Shimane","ror":"https://ror.org/04m42eq84","country_code":"JP","type":"education","lineage":["https://openalex.org/I3129591023"]}],"countries":["JP","SE"],"is_corresponding":false,"raw_author_name":"Kristina Sundquist","raw_affiliation_strings":["Center for Community\u2010Based Healthcare Research and Education (CoHRE), Department of Functional Pathology, School of Medicine Shimane University  Japan","Center for Primary Health Care Research Lund University  Malm\u00f6 Sweden","Center for Community-Based Healthcare Research and Education (CoHRE), Department of Functional Pathology, School of Medicine, Shimane University, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Community\u2010Based Healthcare Research and Education (CoHRE), Department of Functional Pathology, School of Medicine Shimane University  Japan","institution_ids":["https://openalex.org/I169016828","https://openalex.org/I3129591023"]},{"raw_affiliation_string":"Center for Primary Health Care Research Lund University  Malm\u00f6 Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Center for Community-Based Healthcare Research and Education (CoHRE), Department of Functional Pathology, School of Medicine, Shimane University, Japan","institution_ids":["https://openalex.org/I169016828","https://openalex.org/I3129591023"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084812194","display_name":"Jan Sundquist","orcid":"https://orcid.org/0000-0001-7228-5015","observed_orcids":["https://orcid.org/0000-0001-7228-5015"]},"institutions":[{"id":"https://openalex.org/I169016828","display_name":"Shimane University","ror":"https://ror.org/01jaaym28","country_code":"JP","type":"education","lineage":["https://openalex.org/I169016828"]},{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I3129591023","display_name":"University of Shimane","ror":"https://ror.org/04m42eq84","country_code":"JP","type":"education","lineage":["https://openalex.org/I3129591023"]}],"countries":["JP","SE"],"is_corresponding":false,"raw_author_name":"Jan Sundquist","raw_affiliation_strings":["Center for Community\u2010Based Healthcare Research and Education (CoHRE), Department of Functional Pathology, School of Medicine Shimane University  Japan","Center for Primary Health Care Research Lund University  Malm\u00f6 Sweden","Center for Community-Based Healthcare Research and Education (CoHRE), Department of Functional Pathology, School of Medicine, Shimane University, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Community\u2010Based Healthcare Research and Education (CoHRE), Department of Functional Pathology, School of Medicine Shimane University  Japan","institution_ids":["https://openalex.org/I169016828","https://openalex.org/I3129591023"]},{"raw_affiliation_string":"Center for Primary Health Care Research Lund University  Malm\u00f6 Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Center for Community-Based Healthcare Research and Education (CoHRE), Department of Functional Pathology, School of Medicine, Shimane University, Japan","institution_ids":["https://openalex.org/I169016828","https://openalex.org/I3129591023"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080937699","display_name":"Tim Waterboer","orcid":"https://orcid.org/0000-0002-0616-6963","observed_orcids":["https://orcid.org/0000-0002-0616-6963"]},"institutions":[{"id":"https://openalex.org/I17937529","display_name":"German Cancer Research Center","ror":"https://ror.org/04cdgtt98","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I17937529"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Tim Waterboer","raw_affiliation_strings":["Infections and Cancer Epidemiology Division Deutsches Krebsforschungszentrum (DKFZ)  Heidelberg Germany","Infections and Cancer Epidemiology Division, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Infections and Cancer Epidemiology Division Deutsches Krebsforschungszentrum (DKFZ)  Heidelberg Germany","institution_ids":["https://openalex.org/I17937529"]},{"raw_affiliation_string":"Infections and Cancer Epidemiology Division, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany","institution_ids":["https://openalex.org/I17937529"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000871344","display_name":"Matti Lehtinen","orcid":"https://orcid.org/0000-0002-9481-0535","observed_orcids":["https://orcid.org/0000-0002-9481-0535"]},"institutions":[{"id":"https://openalex.org/I17937529","display_name":"German Cancer Research Center","ror":"https://ror.org/04cdgtt98","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I17937529"]},{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["DE","SE"],"is_corresponding":true,"raw_author_name":"Matti Lehtinen","raw_affiliation_strings":["Department of Laboratory Medicine Karolinska Institute  Stockholm Sweden","Infections and Cancer Epidemiology Division Deutsches Krebsforschungszentrum (DKFZ)  Heidelberg Germany","Department of Laboratory Medicine, Karolinska Institute, Stockholm, Sweden","Infections and Cancer Epidemiology Division, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany"],"raw_orcid":"https://orcid.org/0000-0002-9481-0535","affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine Karolinska Institute  Stockholm Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Infections and Cancer Epidemiology Division Deutsches Krebsforschungszentrum (DKFZ)  Heidelberg Germany","institution_ids":["https://openalex.org/I17937529"]},{"raw_affiliation_string":"Department of Laboratory Medicine, Karolinska Institute, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]},{"raw_affiliation_string":"Infections and Cancer Epidemiology Division, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany","institution_ids":["https://openalex.org/I17937529"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090212645","display_name":"Kari Hemminki","orcid":"https://orcid.org/0000-0002-2769-3316","observed_orcids":["https://orcid.org/0000-0002-2769-3316"]},"institutions":[{"id":"https://openalex.org/I17937529","display_name":"German Cancer Research Center","ror":"https://ror.org/04cdgtt98","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I17937529"]},{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]},{"id":"https://openalex.org/I21250087","display_name":"Charles University","ror":"https://ror.org/024d6js02","country_code":"CZ","type":"education","lineage":["https://openalex.org/I21250087"]}],"countries":["CZ","DE","SE"],"is_corresponding":false,"raw_author_name":"Kari Hemminki","raw_affiliation_strings":["Center for Primary Health Care Research Lund University  Malm\u00f6 Sweden","Faculty of Medicine and Biomedical Center in Pilsen Charles University in Prague  Pilsen Czech Republic","Molecular Genetic Epidemiology Division Deutsches Krebsforschungszentrum (DKFZ)  Heidelberg Germany","Faculty of Medicine and Biomedical Center in Pilsen, Charles University in Prague, Pilsen, Czech Republic","Molecular Genetic Epidemiology Division, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Primary Health Care Research Lund University  Malm\u00f6 Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Faculty of Medicine and Biomedical Center in Pilsen Charles University in Prague  Pilsen Czech Republic","institution_ids":["https://openalex.org/I21250087"]},{"raw_affiliation_string":"Molecular Genetic Epidemiology Division Deutsches Krebsforschungszentrum (DKFZ)  Heidelberg Germany","institution_ids":["https://openalex.org/I17937529"]},{"raw_affiliation_string":"Faculty of Medicine and Biomedical Center in Pilsen, Charles University in Prague, Pilsen, Czech Republic","institution_ids":["https://openalex.org/I21250087"]},{"raw_affiliation_string":"Molecular Genetic Epidemiology Division, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany","institution_ids":["https://openalex.org/I17937529"]}]}],"institutions":[],"countries_distinct_count":5,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5000871344"],"corresponding_institution_ids":["https://openalex.org/I17937529","https://openalex.org/I28166907"],"apc_list":{"value":3280,"currency":"USD","value_usd":3280},"apc_paid":{"value":3280,"currency":"USD","value_usd":3280},"fwci":0.7125,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.73571008,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"8","issue":"9","first_page":"e70333","last_page":"e70333"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9628999829292297,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9628999829292297,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":0.03240000084042549,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/human-papillomavirus","display_name":"human papillomavirus","score":0.9300000071525574},{"id":"https://openalex.org/keywords/oropharyngeal-cancer","display_name":"oropharyngeal cancer","score":0.9430000185966492},{"id":"https://openalex.org/keywords/tonsillar-squamous-cell-carcinoma","display_name":"tonsillar squamous cell carcinoma","score":0.9729999899864197},{"id":"https://openalex.org/keywords/base-of-tongue-squamous-cell-carcinoma","display_name":"base of tongue squamous cell carcinoma","score":0.9610000252723694},{"id":"https://openalex.org/keywords/anogenital-cancer","display_name":"anogenital cancer","score":0.906000018119812},{"id":"https://openalex.org/keywords/cervical-carcinoma-in-situ","display_name":"cervical carcinoma in situ","score":0.9319999814033508},{"id":"https://openalex.org/keywords/familial-cancer-risk","display_name":"familial cancer risk","score":0.6570000052452087},{"id":"https://openalex.org/keywords/spouses","display_name":"spouses","score":0.7039999961853027},{"id":"https://openalex.org/keywords/age-at-diagnosis","display_name":"age at diagnosis","score":0.5609999895095825}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7034887671470642},{"id":"https://openalex.org/C82789193","wikidata":"https://www.wikidata.org/wiki/Q2142611","display_name":"Relative risk","level":3,"score":0.6143960356712341},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.592240571975708},{"id":"https://openalex.org/C2994532551","wikidata":"https://www.wikidata.org/wiki/Q184627","display_name":"Human papillomavirus","level":2,"score":0.5114306807518005},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.44811493158340454},{"id":"https://openalex.org/C2778220009","wikidata":"https://www.wikidata.org/wiki/Q160105","display_name":"Cervical cancer","level":3,"score":0.4191456735134125},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.38371461629867554},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3482530117034912},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3253480792045593},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.21879437565803528}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001005","descriptor_name":"Anus Neoplasms","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D001005","descriptor_name":"Anus Neoplasms","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D001005","descriptor_name":"Anus Neoplasms","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D001005","descriptor_name":"Anus Neoplasms","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D001005","descriptor_name":"Anus Neoplasms","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D001005","descriptor_name":"Anus Neoplasms","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D002294","descriptor_name":"Carcinoma, Squamous Cell","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009959","descriptor_name":"Oropharyngeal Neoplasms","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D009959","descriptor_name":"Oropharyngeal Neoplasms","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D009959","descriptor_name":"Oropharyngeal Neoplasms","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D009959","descriptor_name":"Oropharyngeal Neoplasms","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D009959","descriptor_name":"Oropharyngeal Neoplasms","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D009959","descriptor_name":"Oropharyngeal Neoplasms","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013548","descriptor_name":"Sweden","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D013548","descriptor_name":"Sweden","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D013548","descriptor_name":"Sweden","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D014846","descriptor_name":"Vulvar Neoplasms","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D014846","descriptor_name":"Vulvar Neoplasms","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D014846","descriptor_name":"Vulvar Neoplasms","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D014846","descriptor_name":"Vulvar Neoplasms","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D014846","descriptor_name":"Vulvar Neoplasms","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D014846","descriptor_name":"Vulvar Neoplasms","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D018454","descriptor_name":"Spouses","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D018454","descriptor_name":"Spouses","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D018454","descriptor_name":"Spouses","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D027383","descriptor_name":"Papillomaviridae","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D027383","descriptor_name":"Papillomaviridae","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D027383","descriptor_name":"Papillomaviridae","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D030361","descriptor_name":"Papillomavirus Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D030361","descriptor_name":"Papillomavirus Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D030361","descriptor_name":"Papillomavirus Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D030361","descriptor_name":"Papillomavirus Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D030361","descriptor_name":"Papillomavirus Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D030361","descriptor_name":"Papillomavirus Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D030361","descriptor_name":"Papillomavirus Infections","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D030361","descriptor_name":"Papillomavirus Infections","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D030361","descriptor_name":"Papillomavirus Infections","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1002/cnr2.70333","doi":"https://doi.org/10.1002/cnr2.70333","is_oa":true,"landing_page_url":"https://doi.org/10.1002/cnr2.70333","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cnr2.70333","source":{"id":"https://openalex.org/S4210241191","display_name":"Cancer Reports","issn_l":"2573-8348","issn":["2573-8348"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Reports","raw_type":"journal-article"},{"id":"pmid:40877205","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40877205","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer reports (Hoboken, N.J.)","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12394001","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12394001","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cancer Rep (Hoboken)","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:546e46001a124d69bc64d0503a480782","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/546e46001a124d69bc64d0503a480782","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cancer Reports, Vol 8, Iss 9, Pp n/a-n/a (2025)","raw_type":"article"},{"id":"pmh:oai:lup.lub.lu.se:1c4ff785-cf91-4c70-bee5-77c27301da5a","doi":null,"is_oa":false,"landing_page_url":"https://lup.lub.lu.se/record/1c4ff785-cf91-4c70-bee5-77c27301da5a","pdf_url":null,"source":{"id":"https://openalex.org/S4306400536","display_name":"Lund University Publications (Lund University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I187531555","host_organization_name":"Lund University","host_organization_lineage":["https://openalex.org/I187531555"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 2573-8348","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:trepo.tuni.fi:10024/230610","doi":null,"is_oa":true,"landing_page_url":"https://trepo.tuni.fi/handle/10024/230610","pdf_url":null,"source":{"id":"https://openalex.org/S4306401860","display_name":"Tampere University Institutional Repository (Tampere University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I150589677","host_organization_name":"Tampere University of Applied Sciences","host_organization_lineage":["https://openalex.org/I150589677"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"publishedVersion"}],"best_oa_location":{"id":"doi:10.1002/cnr2.70333","doi":"https://doi.org/10.1002/cnr2.70333","is_oa":true,"landing_page_url":"https://doi.org/10.1002/cnr2.70333","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cnr2.70333","source":{"id":"https://openalex.org/S4210241191","display_name":"Cancer Reports","issn_l":"2573-8348","issn":["2573-8348"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G2331508065","display_name":null,"funder_award_id":"847845","funder_id":"https://openalex.org/F4320332999","funder_display_name":"Horizon 2020 Framework Programme"},{"id":"https://openalex.org/G434337789","display_name":null,"funder_award_id":"HORIZON2020","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G4902907177","display_name":"RISK-BASED SCREENING FOR CERVICAL CANCER","funder_award_id":"847845","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320322581","display_name":"Vetenskapsr\u00e5det","ror":"https://ror.org/03zttf063"},{"id":"https://openalex.org/F4320326012","display_name":"Region Sk\u00e5ne","ror":"https://ror.org/03sawy356"},{"id":"https://openalex.org/F4320332999","display_name":"Horizon 2020 Framework Programme","ror":"https://ror.org/00k4n6c32"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4413801596.pdf","grobid_xml":"https://content.openalex.org/works/W4413801596.grobid-xml"},"referenced_works_count":20,"referenced_works":["https://openalex.org/W2019681877","https://openalex.org/W2032952575","https://openalex.org/W2059657958","https://openalex.org/W2061481479","https://openalex.org/W2077083692","https://openalex.org/W2093901599","https://openalex.org/W2107283868","https://openalex.org/W2115317612","https://openalex.org/W2138779768","https://openalex.org/W2325491030","https://openalex.org/W2342166036","https://openalex.org/W2616091843","https://openalex.org/W2747684038","https://openalex.org/W2906339339","https://openalex.org/W2967355900","https://openalex.org/W3106865358","https://openalex.org/W3194573937","https://openalex.org/W4282004105","https://openalex.org/W4296167684","https://openalex.org/W4413801596"],"related_works":["https://openalex.org/W4386948194","https://openalex.org/W2920813532","https://openalex.org/W4213135093","https://openalex.org/W2911638444","https://openalex.org/W2374713766","https://openalex.org/W3199604204","https://openalex.org/W2369168609","https://openalex.org/W2412665400","https://openalex.org/W2754248467","https://openalex.org/W2057530095"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Human":[1],"papillomavirus":[2],"(HPV)":[3],"infection":[4],"is":[5],"associated":[6],"with":[7,28,72,99,135],"tonsillar":[8],"and":[9,45,52,107],"base-of-tongue":[10],"squamous":[11],"cell":[12],"carcinomas":[13],"(TSCC/BOTSCC).":[14],"We":[15,61],"evaluated":[16],"the":[17,24,32,63,114,137],"relative":[18],"risk":[19,154,176],"(RR)":[20],"of":[21,26,65,69,88,93,97,133,144,149,172],"TSCC/BOTSCC":[22,66,94,123,140],"in":[23,67,81,95,122,155,167,177],"husbands":[25,68,87,96,132],"women":[27,70,98,134],"anogenital":[29,73,101],"cancer":[30,55,77,102,153,168,175],"using":[31],"Swedish":[33,38],"family":[34,39],"database.":[35],"METHODS:":[36],"The":[37,91],"database":[40],"includes":[41],"3.5":[42],"million":[43,47],"families":[44],"16":[46],"individuals":[48],"identified":[49],"since":[50],"1932":[51],"linked":[53],"to":[54,59,86,158],"data":[56],"from":[57],"1958":[58],"2015.":[60],"explored":[62],"RR":[64,92,115,138],"diagnosed":[71,125],"(anal,":[74],"vulvar/vaginal,":[75],"cervical)":[76],"or":[78],"cervical":[79],"carcinoma":[80],"situ":[82],"(CIS)":[83],"as":[84],"compared":[85],"controls.":[89],"RESULTS:":[90],"invasive":[100,152],"increased":[103,150],"by":[104],"calendar":[105],"time":[106,145],"decreasing":[108],"ages":[109],"at":[110,117,126],"diagnoses.":[111],"In":[112,131],"2002-2015,":[113],"peaked":[116],"5.35":[118],"(95%":[119],"CI":[120],"2.21-13.0)":[121],"cases":[124],"age":[127],"<":[128],"50":[129],"years.":[130],"CIS,":[136],"for":[139],"was":[141],"2-fold":[142],"irrespective":[143],"period.":[146],"CONCLUSIONS:":[147],"Clustering":[148],"HPV-associated":[151,174],"spouses":[156],"appears":[157],"be":[159],"calendar-time":[160],"dependent.":[161],"This":[162],"introduces":[163],"a":[164],"new":[165],"perspective":[166],"science:":[169],"an":[170],"increase":[171],"familial":[173],"spouses.":[178]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2025-08-29T00:00:00"}