{"id":"https://openalex.org/W4413614237","doi":"https://doi.org/10.1093/rheumatology/keaf451","title":"RA and risk of colorectal cancer: a nationwide cohort study","display_name":"RA and risk of colorectal cancer: a nationwide cohort study","publication_year":2025,"publication_date":"2025-08-23","ids":{"openalex":"https://openalex.org/W4413614237","doi":"https://doi.org/10.1093/rheumatology/keaf451","pmid":"https://pubmed.ncbi.nlm.nih.gov/40855688"},"language":"en","primary_location":{"id":"doi:10.1093/rheumatology/keaf451","doi":"https://doi.org/10.1093/rheumatology/keaf451","is_oa":false,"landing_page_url":"https://doi.org/10.1093/rheumatology/keaf451","pdf_url":null,"source":{"id":"https://openalex.org/S183989336","display_name":"Rheumatology","issn_l":"1462-0324","issn":["1462-0324","1462-0332"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rheumatology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009559779","display_name":"Keun Hye Jeon","orcid":"https://orcid.org/0000-0003-2294-0637","observed_orcids":["https://orcid.org/0000-0003-2294-0637"]},"institutions":[{"id":"https://openalex.org/I4210148737","display_name":"CHA University","ror":"https://ror.org/04yka3j04","country_code":"KR","type":"education","lineage":["https://openalex.org/I4210148737","https://openalex.org/I4405258985"]},{"id":"https://openalex.org/I4405260180","display_name":"CHA Gumi Hospital","ror":"https://ror.org/03cbcg118","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210148737","https://openalex.org/I4405258985","https://openalex.org/I4405260180"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Keun Hye Jeon","raw_affiliation_strings":["Department of Family Medicine, CHA Gumi Medical Center, CHA University School of Medicine , Gumi,","CHA Gumi Medical Center, CHA University School of Medicine Department of Family Medicine, , Gumi, Republic of","Department of Family Medicine, CHA Gumi Medical Center, CHA University School of Medicine, Gumi, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Family Medicine, CHA Gumi Medical Center, CHA University School of Medicine , Gumi,","institution_ids":["https://openalex.org/I4210148737","https://openalex.org/I4405260180"]},{"raw_affiliation_string":"CHA Gumi Medical Center, CHA University School of Medicine Department of Family Medicine, , Gumi, Republic of","institution_ids":["https://openalex.org/I4210148737","https://openalex.org/I4405260180"]},{"raw_affiliation_string":"Department of Family Medicine, CHA Gumi Medical Center, CHA University School of Medicine, Gumi, Republic of Korea","institution_ids":["https://openalex.org/I4210148737","https://openalex.org/I4405260180"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113825877","display_name":"Jin-Hyung Jung","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I848706","display_name":"Sungkyunkwan University","ror":"https://ror.org/04q78tk20","country_code":"KR","type":"education","lineage":["https://openalex.org/I848706"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jinhyung Jung","raw_affiliation_strings":["Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine , Suwon,","Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine , Suwon, Republic of","Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine , Suwon,","institution_ids":["https://openalex.org/I848706"]},{"raw_affiliation_string":"Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine , Suwon, Republic of","institution_ids":["https://openalex.org/I848706"]},{"raw_affiliation_string":"Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea","institution_ids":["https://openalex.org/I848706"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001680111","display_name":"Mi Hee Cho","orcid":"https://orcid.org/0000-0002-3705-0285","observed_orcids":["https://orcid.org/0000-0002-3705-0285"]},"institutions":[{"id":"https://openalex.org/I4210103535","display_name":"Kangbuk Samsung Hospital","ror":"https://ror.org/013e76m06","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I2250650973","https://openalex.org/I2802194831","https://openalex.org/I4210103535"]},{"id":"https://openalex.org/I848706","display_name":"Sungkyunkwan University","ror":"https://ror.org/04q78tk20","country_code":"KR","type":"education","lineage":["https://openalex.org/I848706"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Mi Hee Cho","raw_affiliation_strings":["Samsung C&T Medical Clinic, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine , Seoul,","Samsung C&T Medical Clinic, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine , Seoul, Republic of","Samsung C&T Medical Clinic, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0002-3705-0285","affiliations":[{"raw_affiliation_string":"Samsung C&T Medical Clinic, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine , Seoul,","institution_ids":["https://openalex.org/I4210103535","https://openalex.org/I848706"]},{"raw_affiliation_string":"Samsung C&T Medical Clinic, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine , Seoul, Republic of","institution_ids":["https://openalex.org/I4210103535","https://openalex.org/I848706"]},{"raw_affiliation_string":"Samsung C&T Medical Clinic, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I4210103535","https://openalex.org/I848706"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014354862","display_name":"Dagyeong Lee","orcid":"https://orcid.org/0000-0002-6542-6526","observed_orcids":["https://orcid.org/0000-0002-6542-6526"]},"institutions":[{"id":"https://openalex.org/I4210151365","display_name":"Hallym University Dongtan Sacred Heart Hospital","ror":"https://ror.org/04n278m24","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210151365","https://openalex.org/I4210167048"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Dagyeong Lee","raw_affiliation_strings":["Department of Family Medicine, Hallym University Dongtan Sacred Heart Hospital , Hwaseong,","Department of Family Medicine, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Republic of Korea","Hallym University Dongtan Sacred Heart Hospital Department of Family Medicine, , Hwaseong, Republic of"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Family Medicine, Hallym University Dongtan Sacred Heart Hospital , Hwaseong,","institution_ids":["https://openalex.org/I4210151365"]},{"raw_affiliation_string":"Department of Family Medicine, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Republic of Korea","institution_ids":["https://openalex.org/I4210151365"]},{"raw_affiliation_string":"Hallym University Dongtan Sacred Heart Hospital Department of Family Medicine, , Hwaseong, Republic of","institution_ids":["https://openalex.org/I4210151365"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047846074","display_name":"Kyungdo Han","orcid":"https://orcid.org/0000-0002-6096-1263","observed_orcids":["https://orcid.org/0000-0002-6096-1263"]},"institutions":[{"id":"https://openalex.org/I141371507","display_name":"Soongsil University","ror":"https://ror.org/017xnm587","country_code":"KR","type":"education","lineage":["https://openalex.org/I141371507"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Kyungdo Han","raw_affiliation_strings":["Department of Statistics and Actuarial Science, Soongsil University , Seoul,","Department of Statistics and Actuarial Science, Soongsil University, Seoul, Republic of Korea","Soongsil University Department of Statistics and Actuarial Science, , Seoul, Republic of"],"raw_orcid":"https://orcid.org/0000-0002-6096-1263","affiliations":[{"raw_affiliation_string":"Department of Statistics and Actuarial Science, Soongsil University , Seoul,","institution_ids":["https://openalex.org/I141371507"]},{"raw_affiliation_string":"Department of Statistics and Actuarial Science, Soongsil University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I141371507"]},{"raw_affiliation_string":"Soongsil University Department of Statistics and Actuarial Science, , Seoul, Republic of","institution_ids":["https://openalex.org/I141371507"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034859424","display_name":"In Young Cho","orcid":"https://orcid.org/0000-0002-6265-6342","observed_orcids":["https://orcid.org/0000-0002-6265-6342"]},"institutions":[{"id":"https://openalex.org/I2802194831","display_name":"Samsung Medical Center","ror":"https://ror.org/05a15z872","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I2250650973","https://openalex.org/I2802194831"]},{"id":"https://openalex.org/I848706","display_name":"Sungkyunkwan University","ror":"https://ror.org/04q78tk20","country_code":"KR","type":"education","lineage":["https://openalex.org/I848706"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"In Young Cho","raw_affiliation_strings":["Department of Clinical Research Design and Evaluation, Samsung Advanced Institute for Health Science and Technology (SAIHST), Sungkyunkwan University , Seoul,","Department of Family Medicine/Supportive Care Center, Samsung Medical Center, Sungkyunkwan University School of Medicine , Seoul,","Department of Clinical Research Design and Evaluation, Samsung Advanced Institute for Health Science and Technology, Sungkyunkwan University, Seoul, Republic of Korea","Department of Family Medicine/Supportive Care Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea","Samsung Advanced Institute for Health Science and Technology, Sungkyunkwan University Department of Clinical Research Design and Evaluation, , Seoul, Republic of","Samsung Medical Center, Sungkyunkwan University School of Medicine Department of Family Medicine/Supportive Care Center, , Seoul, Republic of"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Research Design and Evaluation, Samsung Advanced Institute for Health Science and Technology (SAIHST), Sungkyunkwan University , Seoul,","institution_ids":["https://openalex.org/I848706"]},{"raw_affiliation_string":"Department of Family Medicine/Supportive Care Center, Samsung Medical Center, Sungkyunkwan University School of Medicine , Seoul,","institution_ids":["https://openalex.org/I2802194831","https://openalex.org/I848706"]},{"raw_affiliation_string":"Department of Clinical Research Design and Evaluation, Samsung Advanced Institute for Health Science and Technology, Sungkyunkwan University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I848706"]},{"raw_affiliation_string":"Department of Family Medicine/Supportive Care Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I2802194831","https://openalex.org/I848706"]},{"raw_affiliation_string":"Samsung Advanced Institute for Health Science and Technology, Sungkyunkwan University Department of Clinical Research Design and Evaluation, , Seoul, Republic of","institution_ids":["https://openalex.org/I848706"]},{"raw_affiliation_string":"Samsung Medical Center, Sungkyunkwan University School of Medicine Department of Family Medicine/Supportive Care Center, , Seoul, Republic of","institution_ids":["https://openalex.org/I2802194831","https://openalex.org/I848706"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086029573","display_name":"Dong Wook Shin","orcid":"https://orcid.org/0000-0001-8128-8920","observed_orcids":["https://orcid.org/0000-0001-8128-8920"]},"institutions":[{"id":"https://openalex.org/I2802194831","display_name":"Samsung Medical Center","ror":"https://ror.org/05a15z872","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I2250650973","https://openalex.org/I2802194831"]},{"id":"https://openalex.org/I848706","display_name":"Sungkyunkwan University","ror":"https://ror.org/04q78tk20","country_code":"KR","type":"education","lineage":["https://openalex.org/I848706"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Dong Wook Shin","raw_affiliation_strings":["Center for Trend Monitoring-Risk Modeling, Institution of Quality of Life in Cancer, Samsung Medical Center , Seoul,","Department of Clinical Research Design and Evaluation, Samsung Advanced Institute for Health Science and Technology (SAIHST), Sungkyunkwan University , Seoul,","Department of Family Medicine/Supportive Care Center, Samsung Medical Center, Sungkyunkwan University School of Medicine , Seoul,","Center for Trend monitoring-Risk modeling, Institution of Quality of Life in Cancer, Samsung Medical Center","Department of Clinical Research Design and Evaluation, Samsung Advanced Institute for Health Science and Technology, Sungkyunkwan University, Seoul, Republic of Korea","Department of Family Medicine/Supportive Care Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea","Samsung Advanced Institute for Health Science and Technology, Sungkyunkwan University Department of Clinical Research Design and Evaluation, , Seoul, Republic of","Samsung Medical Center Center for Trend monitoring-Risk modeling, Institution of Quality of Life in Cancer,","Samsung Medical Center, Sungkyunkwan University School of Medicine Department of Family Medicine/Supportive Care Center, , Seoul, Republic of"],"raw_orcid":"https://orcid.org/0000-0001-8128-8920","affiliations":[{"raw_affiliation_string":"Center for Trend Monitoring-Risk Modeling, Institution of Quality of Life in Cancer, Samsung Medical Center , Seoul,","institution_ids":["https://openalex.org/I2802194831"]},{"raw_affiliation_string":"Department of Clinical Research Design and Evaluation, Samsung Advanced Institute for Health Science and Technology (SAIHST), Sungkyunkwan University , Seoul,","institution_ids":["https://openalex.org/I848706"]},{"raw_affiliation_string":"Department of Family Medicine/Supportive Care Center, Samsung Medical Center, Sungkyunkwan University School of Medicine , Seoul,","institution_ids":["https://openalex.org/I2802194831","https://openalex.org/I848706"]},{"raw_affiliation_string":"Center for Trend monitoring-Risk modeling, Institution of Quality of Life in Cancer, Samsung Medical Center","institution_ids":["https://openalex.org/I2802194831"]},{"raw_affiliation_string":"Department of Clinical Research Design and Evaluation, Samsung Advanced Institute for Health Science and Technology, Sungkyunkwan University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I848706"]},{"raw_affiliation_string":"Department of Family Medicine/Supportive Care Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I2802194831","https://openalex.org/I848706"]},{"raw_affiliation_string":"Samsung Advanced Institute for Health Science and Technology, Sungkyunkwan University Department of Clinical Research Design and Evaluation, , Seoul, Republic of","institution_ids":["https://openalex.org/I848706"]},{"raw_affiliation_string":"Samsung Medical Center Center for Trend monitoring-Risk modeling, Institution of Quality of Life in Cancer,","institution_ids":["https://openalex.org/I2802194831"]},{"raw_affiliation_string":"Samsung Medical Center, Sungkyunkwan University School of Medicine Department of Family Medicine/Supportive Care Center, , Seoul, Republic of","institution_ids":["https://openalex.org/I2802194831","https://openalex.org/I848706"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5034859424","https://openalex.org/A5086029573"],"corresponding_institution_ids":["https://openalex.org/I2802194831","https://openalex.org/I848706"],"apc_list":{"value":3486,"currency":"GBP","value_usd":4597},"apc_paid":null,"fwci":1.0931,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.72956104,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":96},"biblio":{"volume":"65","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9086999893188477,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9086999893188477,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10552","display_name":"Colorectal Cancer Screening and Detection","score":0.060100000351667404,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10678","display_name":"Inflammatory mediators and NSAID effects","score":0.009999999776482582,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rheumatoid-arthritis","display_name":"rheumatoid arthritis","score":1.0},{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"colorectal cancer","score":0.9599999785423279},{"id":"https://openalex.org/keywords/rectal-cancer","display_name":"rectal cancer","score":0.7990000247955322},{"id":"https://openalex.org/keywords/seronegative-rheumatoid-arthritis","display_name":"seronegative rheumatoid arthritis","score":0.9620000123977661},{"id":"https://openalex.org/keywords/seropositive-rheumatoid-arthritis","display_name":"seropositive rheumatoid arthritis","score":0.996999979019165},{"id":"https://openalex.org/keywords/cancer-risk","display_name":"cancer risk","score":0.7639999985694885},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.6869999766349792},{"id":"https://openalex.org/keywords/cancer-subsite","display_name":"cancer subsite","score":0.4659999907016754},{"id":"https://openalex.org/keywords/cardiometabolic-risk-factors","display_name":"cardiometabolic risk factors","score":0.7059999704360962}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9352625012397766},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8122520446777344},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.7988842725753784},{"id":"https://openalex.org/C2777575956","wikidata":"https://www.wikidata.org/wiki/Q187255","display_name":"Rheumatoid arthritis","level":2,"score":0.7070105075836182},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.6907952427864075},{"id":"https://openalex.org/C2776535787","wikidata":"https://www.wikidata.org/wiki/Q1084257","display_name":"Serostatus","level":4,"score":0.6071544289588928},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.5734029412269592},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.5551413297653198},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.45664095878601074},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.43439218401908875},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.4276966452598572},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.42197349667549133},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.42038068175315857},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.40489277243614197},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.16045862436294556},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001172","descriptor_name":"Arthritis, Rheumatoid","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D001172","descriptor_name":"Arthritis, Rheumatoid","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015994","descriptor_name":"Incidence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016016","descriptor_name":"Proportional Hazards Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056910","descriptor_name":"Republic of Korea","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/rheumatology/keaf451","doi":"https://doi.org/10.1093/rheumatology/keaf451","is_oa":false,"landing_page_url":"https://doi.org/10.1093/rheumatology/keaf451","pdf_url":null,"source":{"id":"https://openalex.org/S183989336","display_name":"Rheumatology","issn_l":"1462-0324","issn":["1462-0324","1462-0332"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rheumatology","raw_type":"journal-article"},{"id":"pmid:40855688","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40855688","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rheumatology (Oxford, England)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W583072873","https://openalex.org/W1971514330","https://openalex.org/W1989574614","https://openalex.org/W2007201440","https://openalex.org/W2040331803","https://openalex.org/W2054136354","https://openalex.org/W2086543401","https://openalex.org/W2093220748","https://openalex.org/W2104388056","https://openalex.org/W2117335168","https://openalex.org/W2127049275","https://openalex.org/W2140065304","https://openalex.org/W2153825864","https://openalex.org/W2543412381","https://openalex.org/W2587440352","https://openalex.org/W2795553077","https://openalex.org/W2883015258","https://openalex.org/W2884727639","https://openalex.org/W2889522041","https://openalex.org/W2891061975","https://openalex.org/W2901170167","https://openalex.org/W3015171497","https://openalex.org/W3128317027","https://openalex.org/W3171954900","https://openalex.org/W3192362443","https://openalex.org/W4206785210","https://openalex.org/W4210327840","https://openalex.org/W4211111012","https://openalex.org/W4213209208","https://openalex.org/W4282825146","https://openalex.org/W4289544525","https://openalex.org/W4308044234","https://openalex.org/W4308769923","https://openalex.org/W4319321357","https://openalex.org/W4378902451","https://openalex.org/W4380562645","https://openalex.org/W4388028467","https://openalex.org/W4388723087","https://openalex.org/W4404639203","https://openalex.org/W4407578747"],"related_works":["https://openalex.org/W4406781087","https://openalex.org/W156307516","https://openalex.org/W4282825146","https://openalex.org/W2138097713","https://openalex.org/W4392280793","https://openalex.org/W3205684808","https://openalex.org/W4389057242","https://openalex.org/W2007201440","https://openalex.org/W4407578747","https://openalex.org/W4412708125"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Prior":[1],"research":[2],"on":[3],"colorectal":[4],"cancer":[5,174,192,243],"(CRC)":[6],"risk":[7,37,122,136,205],"in":[8,141,153,209,237],"RA":[9,25,33,39,58,92,108,118,145,157,167,202,232],"lacked":[10],"analyses":[11,223],"incorporating":[12],"cardiometabolic":[13],"or":[14,189],"behavioural":[15],"factors,":[16],"offered":[17],"limited":[18],"subsite-specific":[19,35],"data":[20],"and":[21,34,61,66,93,109,168,203,233,245],"did":[22],"not":[23,152,181],"consider":[24],"serostatus.":[26,40],"This":[27],"study":[28],"assessed":[29],"the":[30,43,89],"association":[31,90,165,200,230],"between":[32,59,91,166,201,231],"CRC":[36,94,124,138,169,204,234],"by":[38,64],"METHODS:":[41],"Using":[42],"Korean":[44],"National":[45],"Health":[46],"Insurance":[47],"System":[48],"database,":[49],"we":[50],"identified":[51],"40":[52],"909":[53],"patients":[54,142,238],"with":[55,72,107,114,117,126,143,155,239],"newly":[56],"diagnosed":[57,113],"2010":[60],"2017,":[62],"matched":[63],"age":[65],"sex":[67],"at":[68],"a":[69,98,120],"1:5":[70],"ratio":[71,86],"204":[73],"545":[74],"non-RA":[75,127],"participants.":[76],"Multivariable":[77],"Cox":[78],"regression":[79],"models":[80],"were":[81,112],"used":[82],"to":[83],"estimate":[84],"hazard":[85],"(HR)":[87],"for":[88,123,172,182,217],"incidence.":[95],"RESULTS:":[96],"During":[97],"median":[99],"follow-up":[100],"of":[101,137,227],"5.3":[102],"years,":[103],"2174":[104],"subjects":[105],"(319":[106],"1855":[110],"controls)":[111],"CRC.":[115],"Patients":[116],"had":[119],"decreased":[121,135],"compared":[125],"participants":[128],"(HR,":[129,146,158,175,184,193,211],"0.89;":[130],"95%":[131,148,160,177,186,195,213],"CI,":[132,149,161,178,187,196,214],"0.79-0.99).":[133],"A":[134],"was":[139,170,206],"found":[140],"seronegative":[144,240],"0.79;":[147],"0.63-0.98)":[150],"but":[151,180],"those":[154],"seropositive":[156],"0.93;":[159],"0.81-1.06).":[162],"The":[163,198],"inverse":[164,199,229],"significant":[171],"rectal":[173,242],"0.63;":[176],"0.45-0.87)":[179],"proximal":[183],"1.04;":[185],"0.79-1.39)":[188],"distal":[190],"colon":[191],"0.84;":[194],"0.64-1.11).":[197],"more":[207],"pronounced":[208],"women":[210],"0.80;":[212],"0.69-0.94;":[215],"P":[216],"interaction":[218],"=":[219],"0.043).":[220],"CONCLUSIONS:":[221],"Our":[222],"provide":[224],"solid":[225],"evidence":[226],"an":[228],"risk,":[235],"particularly":[236],"RA,":[241],"cases":[244],"women.":[246]},"counts_by_year":[{"year":2026,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2025-10-10T00:00:00"}