{"id":"https://openalex.org/W4413312992","doi":"https://doi.org/10.1016/j.compbiomed.2025.110905","title":"A computational pipeline for clustering left atrial appendage morphology via elastic shape analysis","display_name":"A computational pipeline for clustering left atrial appendage morphology via elastic shape analysis","publication_year":2025,"publication_date":"2025-08-18","ids":{"openalex":"https://openalex.org/W4413312992","doi":"https://doi.org/10.1016/j.compbiomed.2025.110905","pmid":"https://pubmed.ncbi.nlm.nih.gov/40829350"},"language":"en","primary_location":{"id":"doi:10.1016/j.compbiomed.2025.110905","doi":"https://doi.org/10.1016/j.compbiomed.2025.110905","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.compbiomed.2025.110905","pdf_url":null,"source":{"id":"https://openalex.org/S44278595","display_name":"Computers in Biology and Medicine","issn_l":"0010-4825","issn":["0010-4825","1879-0534"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computers in Biology and Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002713389","display_name":"Zan Ahmad","orcid":"https://orcid.org/0000-0002-1668-0034","observed_orcids":["https://orcid.org/0000-0002-1668-0034"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Zan Ahmad","raw_affiliation_strings":["Department of Applied Mathematics and Statistics, Johns Hopkins University, Baltimore, MD, USA; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA. Electronic address: zahmad6@jhu.edu"],"raw_orcid":"https://orcid.org/0000-0002-1668-0034","affiliations":[{"raw_affiliation_string":"Department of Applied Mathematics and Statistics, Johns Hopkins University, Baltimore, MD, USA; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA. Electronic address: zahmad6@jhu.edu","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057909836","display_name":"Minglang Yin","orcid":"https://orcid.org/0000-0001-7861-350X","observed_orcids":["https://orcid.org/0000-0001-7861-350X"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Minglang Yin","raw_affiliation_strings":["Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066533620","display_name":"Yashil Sukurdeep","orcid":"https://orcid.org/0000-0002-4980-4291","observed_orcids":["https://orcid.org/0000-0002-4980-4291"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yashil Sukurdeep","raw_affiliation_strings":["Department of Applied Mathematics and Statistics, Johns Hopkins University, Baltimore, MD, USA"],"raw_orcid":"https://orcid.org/0000-0002-4980-4291","affiliations":[{"raw_affiliation_string":"Department of Applied Mathematics and Statistics, Johns Hopkins University, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5094157143","display_name":"Noam Rotenberg","orcid":"https://orcid.org/0000-0003-3086-1365","observed_orcids":["https://orcid.org/0000-0003-3086-1365"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Noam Rotenberg","raw_affiliation_strings":["Department of Applied Mathematics and Statistics, Johns Hopkins University, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Applied Mathematics and Statistics, Johns Hopkins University, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057622454","display_name":"Eugene G. Kholmovski","orcid":"https://orcid.org/0000-0002-3271-7247","observed_orcids":["https://orcid.org/0000-0002-3271-7247"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eugene Kholmovksi","raw_affiliation_strings":["Department of Applied Mathematics and Statistics, Johns Hopkins University, Baltimore, MD, USA"],"raw_orcid":"https://orcid.org/0000-0002-3271-7247","affiliations":[{"raw_affiliation_string":"Department of Applied Mathematics and Statistics, Johns Hopkins University, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070924694","display_name":"Natalia A. Trayanova","orcid":"https://orcid.org/0000-0002-8661-063X","observed_orcids":["https://orcid.org/0000-0002-8661-063X"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Natalia Trayanova","raw_affiliation_strings":["Department of Applied Mathematics and Statistics, Johns Hopkins University, Baltimore, MD, USA; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Applied Mathematics and Statistics, Johns Hopkins University, Baltimore, MD, USA; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5002713389"],"corresponding_institution_ids":["https://openalex.org/I145311948"],"apc_list":{"value":3080,"currency":"USD","value_usd":3080},"apc_paid":null,"fwci":0.6933,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.74088867,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"196","issue":"Pt C","first_page":"110905","last_page":"110905"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":0.6791999936103821,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":0.6791999936103821,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12536","display_name":"Topological and Geometric Data Analysis","score":0.049800001084804535,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11217","display_name":"Cardiac Arrhythmias and Treatments","score":0.03909999877214432,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/left-atrial-appendage","display_name":"left atrial appendage","score":0.9700000286102295},{"id":"https://openalex.org/keywords/atrial-fibrillation","display_name":"atrial fibrillation","score":0.8550000190734863},{"id":"https://openalex.org/keywords/ischemic-stroke-risk","display_name":"ischemic stroke risk","score":0.8259999752044678},{"id":"https://openalex.org/keywords/elastic-shape-analysis","display_name":"elastic shape analysis","score":0.9599999785423279},{"id":"https://openalex.org/keywords/unsupervised-clustering","display_name":"unsupervised clustering","score":0.8140000104904175},{"id":"https://openalex.org/keywords/morphological-classification","display_name":"morphological classification","score":0.5740000009536743},{"id":"https://openalex.org/keywords/stroke-risk-stratification","display_name":"stroke risk stratification","score":0.7620000243186951},{"id":"https://openalex.org/keywords/geometric-features","display_name":"geometric features","score":0.5440000295639038}],"concepts":[{"id":"https://openalex.org/C41451933","wikidata":"https://www.wikidata.org/wiki/Q13415392","display_name":"Appendage","level":2,"score":0.9296958446502686},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.6430180668830872},{"id":"https://openalex.org/C499950583","wikidata":"https://www.wikidata.org/wiki/Q183252","display_name":"Morphology (biology)","level":2,"score":0.6225543022155762},{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.5544440746307373},{"id":"https://openalex.org/C2910272107","wikidata":"https://www.wikidata.org/wiki/Q1615482","display_name":"Atrial Appendage","level":4,"score":0.5278915166854858},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3927197754383087},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.2875679135322571},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2763526439666748},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.20653170347213745},{"id":"https://openalex.org/C127313418","wikidata":"https://www.wikidata.org/wiki/Q1069","display_name":"Geology","level":0,"score":0.18623894453048706},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.1763756275177002},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.16989865899085999},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.16860762238502502},{"id":"https://openalex.org/C2775914520","wikidata":"https://www.wikidata.org/wiki/Q12335414","display_name":"Sinus rhythm","level":3,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001281","descriptor_name":"Atrial Fibrillation","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020517","descriptor_name":"Atrial Appendage","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D020517","descriptor_name":"Atrial Appendage","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D020517","descriptor_name":"Atrial Appendage","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.compbiomed.2025.110905","doi":"https://doi.org/10.1016/j.compbiomed.2025.110905","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.compbiomed.2025.110905","pdf_url":null,"source":{"id":"https://openalex.org/S44278595","display_name":"Computers in Biology and Medicine","issn_l":"0010-4825","issn":["0010-4825","1879-0534"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computers in Biology and Medicine","raw_type":"journal-article"},{"id":"pmid:40829350","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40829350","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computers in biology and medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2597965206","display_name":null,"funder_award_id":"T32 HL007024","funder_id":"https://openalex.org/F4320306230","funder_display_name":"American Heart Association"},{"id":"https://openalex.org/G3836119140","display_name":"Infarct-related Ventricular Tachycardia Mechanisms:  From Micro to Clinical","funder_award_id":"R01HL142496","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G9000867194","display_name":"Cardiovascular Epidemiology Institutional Training","funder_award_id":"T32HL007024","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G9000903272","display_name":"Artificial intelligence analysis of atrial remodeling evolution in patients with atrial fibrillation: Towards optimal ablation strategies","funder_award_id":"R01HL166759","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320306230","display_name":"American Heart Association","ror":"https://ror.org/013kjyp64"},{"id":"https://openalex.org/F4320308778","display_name":"Heart Rhythm Society","ror":"https://ror.org/035m9ft70"},{"id":"https://openalex.org/F4320320890","display_name":"Fondation Leducq","ror":"https://ror.org/01czwga19"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":49,"referenced_works":["https://openalex.org/W1534370115","https://openalex.org/W1977272864","https://openalex.org/W1987971958","https://openalex.org/W1993436046","https://openalex.org/W2001141328","https://openalex.org/W2025521473","https://openalex.org/W2047161559","https://openalex.org/W2051224630","https://openalex.org/W2085487226","https://openalex.org/W2114775432","https://openalex.org/W2120043163","https://openalex.org/W2121767516","https://openalex.org/W2123607323","https://openalex.org/W2129066856","https://openalex.org/W2170167891","https://openalex.org/W2297300098","https://openalex.org/W2329336885","https://openalex.org/W2741275949","https://openalex.org/W2759186014","https://openalex.org/W2903450557","https://openalex.org/W2904051237","https://openalex.org/W2911557083","https://openalex.org/W2938155890","https://openalex.org/W2957544571","https://openalex.org/W2995812482","https://openalex.org/W3024327240","https://openalex.org/W3025624016","https://openalex.org/W3036104060","https://openalex.org/W3102383992","https://openalex.org/W3119677668","https://openalex.org/W3126207353","https://openalex.org/W3159964121","https://openalex.org/W3183913336","https://openalex.org/W4253997883","https://openalex.org/W4285816849","https://openalex.org/W4292554553","https://openalex.org/W4313585075","https://openalex.org/W4317606129","https://openalex.org/W4372050335","https://openalex.org/W4377016241","https://openalex.org/W4379515222","https://openalex.org/W4390872893","https://openalex.org/W4391799354","https://openalex.org/W4395465169","https://openalex.org/W4395481429","https://openalex.org/W4403313247","https://openalex.org/W4403911399","https://openalex.org/W6757096879","https://openalex.org/W6963566491"],"related_works":["https://openalex.org/W2911557083","https://openalex.org/W4409739078","https://openalex.org/W3159964121","https://openalex.org/W7161474072","https://openalex.org/W2793348247","https://openalex.org/W3014810319","https://openalex.org/W4402623720","https://openalex.org/W1541730289","https://openalex.org/W4391799354","https://openalex.org/W7027474834"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2025-10-10T00:00:00"}