{"id":"https://openalex.org/W4413106906","doi":"https://doi.org/10.1111/vox.70090","title":"Three buffy coat platelet concentrates: Use of data modelling to make more with less","display_name":"Three buffy coat platelet concentrates: Use of data modelling to make more with less","publication_year":2025,"publication_date":"2025-08-11","ids":{"openalex":"https://openalex.org/W4413106906","doi":"https://doi.org/10.1111/vox.70090","pmid":"https://pubmed.ncbi.nlm.nih.gov/40789580"},"language":"en","primary_location":{"id":"doi:10.1111/vox.70090","doi":"https://doi.org/10.1111/vox.70090","is_oa":true,"landing_page_url":"https://doi.org/10.1111/vox.70090","pdf_url":null,"source":{"id":"https://openalex.org/S56953219","display_name":"Vox Sanguinis","issn_l":"0042-9007","issn":["0042-9007","1423-0410"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vox Sanguinis","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1111/vox.70090","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5116576850","display_name":"Michael Cahillane","orcid":"https://orcid.org/0009-0009-5211-920X","observed_orcids":["https://orcid.org/0009-0009-5211-920X"]},"institutions":[{"id":"https://openalex.org/I4405253097","display_name":"Welsh Blood Service","ror":"https://ror.org/00a775j83","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4405253097"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Michael Cahillane","raw_affiliation_strings":["Welsh Blood Service  Pontyclun UK","Welsh Blood Service, Pontyclun, UK"],"raw_orcid":"https://orcid.org/0009-0009-5211-920X","affiliations":[{"raw_affiliation_string":"Welsh Blood Service  Pontyclun UK","institution_ids":["https://openalex.org/I4405253097"]},{"raw_affiliation_string":"Welsh Blood Service, Pontyclun, UK","institution_ids":["https://openalex.org/I4405253097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034470741","display_name":"Nicola Pearce","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405253097","display_name":"Welsh Blood Service","ror":"https://ror.org/00a775j83","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4405253097"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nicola Pearce","raw_affiliation_strings":["Welsh Blood Service  Pontyclun UK","Welsh Blood Service, Pontyclun, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Welsh Blood Service  Pontyclun UK","institution_ids":["https://openalex.org/I4405253097"]},{"raw_affiliation_string":"Welsh Blood Service, Pontyclun, UK","institution_ids":["https://openalex.org/I4405253097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026694753","display_name":"Christine V. Saunders","orcid":"https://orcid.org/0000-0002-7010-6068","observed_orcids":["https://orcid.org/0000-0002-7010-6068"]},"institutions":[{"id":"https://openalex.org/I4405253097","display_name":"Welsh Blood Service","ror":"https://ror.org/00a775j83","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4405253097"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Christine Saunders","raw_affiliation_strings":["Welsh Blood Service  Pontyclun UK","Welsh Blood Service, Pontyclun, UK"],"raw_orcid":"https://orcid.org/0000-0002-7010-6068","affiliations":[{"raw_affiliation_string":"Welsh Blood Service  Pontyclun UK","institution_ids":["https://openalex.org/I4405253097"]},{"raw_affiliation_string":"Welsh Blood Service, Pontyclun, UK","institution_ids":["https://openalex.org/I4405253097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5119269025","display_name":"Nicole Polidano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405253097","display_name":"Welsh Blood Service","ror":"https://ror.org/00a775j83","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4405253097"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nicole Polidano","raw_affiliation_strings":["Welsh Blood Service  Pontyclun UK","Welsh Blood Service, Pontyclun, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Welsh Blood Service  Pontyclun UK","institution_ids":["https://openalex.org/I4405253097"]},{"raw_affiliation_string":"Welsh Blood Service, Pontyclun, UK","institution_ids":["https://openalex.org/I4405253097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5120391676","display_name":"Stephanie O'Brien","orcid":"https://orcid.org/0000-0001-8855-9746","observed_orcids":["https://orcid.org/0000-0001-8855-9746"]},"institutions":[{"id":"https://openalex.org/I4210150388","display_name":"Velindre Cancer Centre","ror":"https://ror.org/049sr1d03","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799279586","https://openalex.org/I4210150388"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Stephanie O'Brien","raw_affiliation_strings":["Velindre Cancer Centre  Cardiff UK","Velindre Cancer Centre, Cardiff, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Velindre Cancer Centre  Cardiff UK","institution_ids":["https://openalex.org/I4210150388"]},{"raw_affiliation_string":"Velindre Cancer Centre, Cardiff, UK","institution_ids":["https://openalex.org/I4210150388"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5119269026","display_name":"Laura Paletto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405253097","display_name":"Welsh Blood Service","ror":"https://ror.org/00a775j83","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4405253097"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Laura Paletto","raw_affiliation_strings":["Welsh Blood Service  Pontyclun UK","Welsh Blood Service, Pontyclun, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Welsh Blood Service  Pontyclun UK","institution_ids":["https://openalex.org/I4405253097"]},{"raw_affiliation_string":"Welsh Blood Service, Pontyclun, UK","institution_ids":["https://openalex.org/I4405253097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035205666","display_name":"Thomas G. Scorer","orcid":"https://orcid.org/0000-0003-4106-2286","observed_orcids":["https://orcid.org/0000-0003-4106-2286"]},"institutions":[{"id":"https://openalex.org/I4210166818","display_name":"University Hospitals Plymouth NHS Trust","ror":"https://ror.org/05x3jck08","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210166818"]},{"id":"https://openalex.org/I4405273129","display_name":"Royal Centre for Defence Medicine","ror":"https://ror.org/05atb2w70","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4405273129"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Thomas Scorer","raw_affiliation_strings":["Centre of Defence Pathology Royal Centre for Defence Medicine  Birmingham UK","University Hospitals Plymouth, NHS Trust  Plymouth UK","Centre of Defence Pathology, Royal Centre for Defence Medicine, Birmingham, UK","University Hospitals Plymouth, NHS Trust, Plymouth, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre of Defence Pathology Royal Centre for Defence Medicine  Birmingham UK","institution_ids":["https://openalex.org/I4405273129"]},{"raw_affiliation_string":"University Hospitals Plymouth, NHS Trust  Plymouth UK","institution_ids":["https://openalex.org/I4210166818"]},{"raw_affiliation_string":"Centre of Defence Pathology, Royal Centre for Defence Medicine, Birmingham, UK","institution_ids":["https://openalex.org/I4405273129"]},{"raw_affiliation_string":"University Hospitals Plymouth, NHS Trust, Plymouth, UK","institution_ids":["https://openalex.org/I4210166818"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090890896","display_name":"Chlo\u00eb E. George","orcid":"https://orcid.org/0000-0003-3857-378X","observed_orcids":["https://orcid.org/0000-0003-3857-378X"]},"institutions":[{"id":"https://openalex.org/I4405253097","display_name":"Welsh Blood Service","ror":"https://ror.org/00a775j83","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4405253097"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Chloe George","raw_affiliation_strings":["Welsh Blood Service  Pontyclun UK","Welsh Blood Service, Pontyclun, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Welsh Blood Service  Pontyclun UK","institution_ids":["https://openalex.org/I4405253097"]},{"raw_affiliation_string":"Welsh Blood Service, Pontyclun, UK","institution_ids":["https://openalex.org/I4405253097"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5116576850"],"corresponding_institution_ids":["https://openalex.org/I4405253097"],"apc_list":{"value":4150,"currency":"USD","value_usd":4150},"apc_paid":{"value":4150,"currency":"USD","value_usd":4150},"fwci":0.8061,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.74554001,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"120","issue":"11","first_page":"1123","last_page":"1131"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.7734000086784363,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.7734000086784363,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12735","display_name":"Blood donation and transfusion practices","score":0.22030000388622284,"subfield":{"id":"https://openalex.org/subfields/1405","display_name":"Management of Technology and Innovation"},"field":{"id":"https://openalex.org/fields/14","display_name":"Business, Management and Accounting"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11116","display_name":"Trauma, Hemostasis, Coagulopathy, Resuscitation","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/platelet-recovery","display_name":"platelet recovery","score":0.6259999871253967},{"id":"https://openalex.org/keywords/platelet-yield","display_name":"platelet yield","score":0.8479999899864197},{"id":"https://openalex.org/keywords/pooled-platelet-concentrates","display_name":"pooled platelet concentrates","score":0.7710000276565552},{"id":"https://openalex.org/keywords/production-capacity","display_name":"production capacity","score":0.6779999732971191},{"id":"https://openalex.org/keywords/supply-chain-resilience","display_name":"supply chain resilience","score":0.777999997138977},{"id":"https://openalex.org/keywords/manufacturing-variability","display_name":"manufacturing variability","score":0.5640000104904175}],"concepts":[{"id":"https://openalex.org/C2778285947","wikidata":"https://www.wikidata.org/wiki/Q548079","display_name":"Buffy coat","level":2,"score":0.73606276512146},{"id":"https://openalex.org/C2778348673","wikidata":"https://www.wikidata.org/wiki/Q739302","display_name":"Production (economics)","level":2,"score":0.6423036456108093},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.4353582561016083},{"id":"https://openalex.org/C21547014","wikidata":"https://www.wikidata.org/wiki/Q1423657","display_name":"Operations management","level":1,"score":0.39447587728500366},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.38062697649002075},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.27339306473731995},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.27310800552368164},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2615373432636261},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.14447304606437683},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.09335273504257202},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001792","descriptor_name":"Blood Platelets","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D001792","descriptor_name":"Blood Platelets","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D006113","descriptor_name":"United Kingdom","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006113","descriptor_name":"United Kingdom","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017713","descriptor_name":"Platelet Transfusion","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D017713","descriptor_name":"Platelet Transfusion","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D058621","descriptor_name":"Blood Buffy Coat","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D058621","descriptor_name":"Blood Buffy Coat","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1111/vox.70090","doi":"https://doi.org/10.1111/vox.70090","is_oa":true,"landing_page_url":"https://doi.org/10.1111/vox.70090","pdf_url":null,"source":{"id":"https://openalex.org/S56953219","display_name":"Vox Sanguinis","issn_l":"0042-9007","issn":["0042-9007","1423-0410"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vox Sanguinis","raw_type":"journal-article"},{"id":"pmid:40789580","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40789580","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vox sanguinis","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:11410581","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12602124","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1111/vox.70090","doi":"https://doi.org/10.1111/vox.70090","is_oa":true,"landing_page_url":"https://doi.org/10.1111/vox.70090","pdf_url":null,"source":{"id":"https://openalex.org/S56953219","display_name":"Vox Sanguinis","issn_l":"0042-9007","issn":["0042-9007","1423-0410"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vox Sanguinis","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5683000087738037}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W1588487590","https://openalex.org/W2059196175","https://openalex.org/W2093255106","https://openalex.org/W2100269967","https://openalex.org/W2107026277","https://openalex.org/W2564420797","https://openalex.org/W2608274567","https://openalex.org/W2612517915","https://openalex.org/W2795843143","https://openalex.org/W2900555696","https://openalex.org/W3039544106","https://openalex.org/W3099562213","https://openalex.org/W3176551690","https://openalex.org/W4367668322","https://openalex.org/W4392286878","https://openalex.org/W4401937404","https://openalex.org/W6730869652","https://openalex.org/W6862059745"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W1592218061","https://openalex.org/W2887839840","https://openalex.org/W4309960639","https://openalex.org/W2976588203","https://openalex.org/W2074767337","https://openalex.org/W1976368412","https://openalex.org/W2566415539"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"and":[2,41,58,75,105,119,200,226,237],"Objectives":[3],"The":[4],"Welsh":[5],"Blood":[6],"Service":[7],"(WBS)":[8],"produces":[9],"pooled":[10],"platelet":[11,21,30,190],"concentrates":[12,31],"from":[13,65,78,162],"four":[14],"buffy":[15,28],"coats":[16],"(4BC\u2010PC),":[17],"achieving":[18,143,155,172],"consistently":[19],"high":[20],"yields":[22,98],"exceeding":[23],"the":[24,34,51,79,92,123,180,231,239],"UK":[25,106,134,169,224,232],"specification.":[26],"Three":[27],"coat":[29],"(3BC\u2010PC)":[32],"offer":[33],"potential":[35,187],"for":[36,112,179,197,241],"improved":[37],"supply":[38],"chain":[39],"resilience":[40],"increased":[42,218],"production":[43,110,219],"capacity.":[44,220],"Data":[45,126,207],"modelling":[46,127,208],"was":[47,63,235],"performed":[48],"to":[49,68,84,151,164,167,215],"evaluate":[50],"local":[52],"feasibility":[53],"of":[54,94,122,203],"3BC\u2010PC":[55,86,129,210,222],"production.":[56],"Materials":[57],"Methods":[59],"Platelet":[60],"recovery":[61],"(%)":[62],"calculated":[64],"41":[66],"4BC\u2010PC":[67],"generate":[69],"three":[70,181],"reference":[71],"values":[72],"(maximum,":[73],"average":[74],"minimum).":[76],"Measurements":[77],"164":[80],"BCs":[81],"were":[82,99,114],"used":[83],"model":[85],"production,":[87,193],"with":[88,128,194,230],"further":[89,242],"analysis":[90],"determining":[91],"impacts":[93],"manufacturing":[95],"variability.":[96],"Calculated":[97],"assessed":[100],"against":[101,133],"UK,":[102],"European":[103],"(EU)":[104],"contingency":[107,140,225],"specifications.":[108,228],"Potential":[109],"increases":[111,188],"WBS":[113],"estimated":[115],"alongside":[116],"statistical":[117],"significance":[118],"effect":[120],"size":[121],"modelling.":[124],"Results":[125],"showed":[130],"100%":[131],"compliance":[132,150],"minimum":[135],"requirements":[136],"approved":[137],"as":[138,211],"a":[139,212,251],"measure":[141],"(\u226575%":[142,171],"\u2265150":[144],"\u00d7":[145,157,174],"10":[146,158,175],"9":[147,159,176],"/unit),":[148],"while":[149],"EU":[152,227],"specification":[153,170,234],"(\u226590%":[154],"\u2265200":[156],"/unit)":[160,177],"ranged":[161],"93.2%":[163],"100%.":[165],"Compliance":[166,229],"routine":[168],"\u2265240":[173],"varied":[178],"modelled":[182],"scenarios":[183],"(54.5%\u201386.8%).":[184],"Modelling":[185],"indicated":[186],"in":[189],"concentrate":[191],"(PC)":[192],"notable":[195],"rises":[196],"Groups":[198],"A":[199],"O":[201],"components":[202],"approximately":[204],"30%\u201340%.":[205],"Conclusion":[206],"supports":[209],"feasible":[213],"alternative":[214],"4BC\u2010PC,":[216],"offering":[217],"Modelled":[221],"met":[223],"standard":[233],"variable":[236],"suggests":[238],"need":[240],"optimization.":[243],"Real\u2010world":[244],"validation":[245],"would":[246],"confirm":[247],"whether":[248],"this":[249],"is":[250],"practical":[252],"proposition.":[253]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-13T10:08:12.033832","created_date":"2025-10-10T00:00:00"}