{"id":"https://openalex.org/W4413085517","doi":"https://doi.org/10.53555/ja43v365","title":"STUDY OF CO RELATION OF ANTI STREPTOLYSIN-O ANTIBODY TITRE AMONG THE SUSPECTED PATIENTS WITH STREPTOCOCCAL INFECTION AT TERTIARY CARE CENTRE.","display_name":"STUDY OF CO RELATION OF ANTI STREPTOLYSIN-O ANTIBODY TITRE AMONG THE SUSPECTED PATIENTS WITH STREPTOCOCCAL INFECTION AT TERTIARY CARE CENTRE.","publication_year":2024,"publication_date":"2024-12-12","ids":{"openalex":"https://openalex.org/W4413085517","doi":"https://doi.org/10.53555/ja43v365"},"language":"en","primary_location":{"id":"doi:10.53555/ja43v365","doi":"https://doi.org/10.53555/ja43v365","is_oa":true,"landing_page_url":"https://doi.org/10.53555/ja43v365","pdf_url":"https://www.jptcp.com/index.php/jptcp/article/download/10535/9819","source":{"id":"https://openalex.org/S4210224141","display_name":"Journal of Population Therapeutics and Clinical Pharmacology","issn_l":"1710-6222","issn":["1710-6222","1198-581X","2561-8741"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310318016","host_organization_name":"Codon Publications","host_organization_lineage":["https://openalex.org/P4310318016"],"host_organization_lineage_names":["Codon Publications"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Population Therapeutics and Clinical Pharmacology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.jptcp.com/index.php/jptcp/article/download/10535/9819","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010160601","display_name":"Sachin M Darji","orcid":"https://orcid.org/0009-0002-2329-1042","observed_orcids":["https://orcid.org/0009-0002-2329-1042"]},"institutions":[{"id":"https://openalex.org/I4405260799","display_name":"GCS Medical College","ror":"https://ror.org/049s68q83","country_code":"IN","type":"education","lineage":["https://openalex.org/I4210089564","https://openalex.org/I4405260799"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Dr. Sachin M. Darji","raw_affiliation_strings":["Assistant professor , M.D. (Microbiology) , Microbiology department , GCS Medical College , Ahmedabad , Gujarat , India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Assistant professor , M.D. (Microbiology) , Microbiology department , GCS Medical College , Ahmedabad , Gujarat , India","institution_ids":["https://openalex.org/I4405260799"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5010160601"],"corresponding_institution_ids":["https://openalex.org/I4405260799"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"12","last_page":"22"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11153","display_name":"Streptococcal Infections and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11153","display_name":"Streptococcal Infections and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12297","display_name":"Otolaryngology and Infectious Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12914","display_name":"Infectious Disease Case Reports and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/streptococcus-pyogenes","display_name":"Streptococcus pyogenes","score":0.8140000104904175},{"id":"https://openalex.org/keywords/streptococcal-infection","display_name":"streptococcal infection","score":0.8889999985694885},{"id":"https://openalex.org/keywords/rheumatic-fever","display_name":"rheumatic fever","score":0.8410000205039978},{"id":"https://openalex.org/keywords/seroprevalence","display_name":"seroprevalence","score":0.8169999718666077},{"id":"https://openalex.org/keywords/age-related-prevalence","display_name":"age-related prevalence","score":0.5479999780654907},{"id":"https://openalex.org/keywords/sore-throat","display_name":"sore throat","score":0.8299999833106995},{"id":"https://openalex.org/keywords/serological-diagnosis","display_name":"serological diagnosis","score":0.5410000085830688},{"id":"https://openalex.org/keywords/jones-criteria","display_name":"Jones criteria","score":0.6809999942779541}],"concepts":[{"id":"https://openalex.org/C2991842025","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Tertiary care","level":2,"score":0.8114597797393799},{"id":"https://openalex.org/C2776993315","wikidata":"https://www.wikidata.org/wiki/Q418187","display_name":"Streptolysin","level":4,"score":0.6762921810150146},{"id":"https://openalex.org/C32611913","wikidata":"https://www.wikidata.org/wiki/Q2166189","display_name":"Titer","level":3,"score":0.6127734184265137},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.49852991104125977},{"id":"https://openalex.org/C22889606","wikidata":"https://www.wikidata.org/wiki/Q2166189","display_name":"Antibody titer","level":4,"score":0.48382845520973206},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.45956259965896606},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.38985753059387207},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.35982954502105713},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.31010302901268005},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.24398773908615112},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.18724298477172852},{"id":"https://openalex.org/C2993175405","wikidata":"https://www.wikidata.org/wiki/Q8054","display_name":"Bacterial protein","level":3,"score":0.1807056963443756},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11967247724533081},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.53555/ja43v365","doi":"https://doi.org/10.53555/ja43v365","is_oa":true,"landing_page_url":"https://doi.org/10.53555/ja43v365","pdf_url":"https://www.jptcp.com/index.php/jptcp/article/download/10535/9819","source":{"id":"https://openalex.org/S4210224141","display_name":"Journal of Population Therapeutics and Clinical Pharmacology","issn_l":"1710-6222","issn":["1710-6222","1198-581X","2561-8741"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310318016","host_organization_name":"Codon Publications","host_organization_lineage":["https://openalex.org/P4310318016"],"host_organization_lineage_names":["Codon Publications"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Population Therapeutics and Clinical Pharmacology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.53555/ja43v365","doi":"https://doi.org/10.53555/ja43v365","is_oa":true,"landing_page_url":"https://doi.org/10.53555/ja43v365","pdf_url":"https://www.jptcp.com/index.php/jptcp/article/download/10535/9819","source":{"id":"https://openalex.org/S4210224141","display_name":"Journal of Population Therapeutics and Clinical Pharmacology","issn_l":"1710-6222","issn":["1710-6222","1198-581X","2561-8741"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310318016","host_organization_name":"Codon Publications","host_organization_lineage":["https://openalex.org/P4310318016"],"host_organization_lineage_names":["Codon Publications"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Population Therapeutics and Clinical Pharmacology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4413085517.pdf","grobid_xml":"https://content.openalex.org/works/W4413085517.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2467060887","https://openalex.org/W1556406835","https://openalex.org/W3093894219","https://openalex.org/W4214594358","https://openalex.org/W4214485678","https://openalex.org/W2472188492","https://openalex.org/W2608880718","https://openalex.org/W2894277379","https://openalex.org/W3011296995","https://openalex.org/W7169754475"],"abstract_inverted_index":{"Background:":[0],"Rheumatic":[1],"fever":[2],"(RF)":[3],"is":[4,35,316,330,340],"a":[5,317],"common":[6],"public":[7],"health":[8],"concern":[9],"in":[10,51,64,75,91,106,123,306,356,369],"India,":[11],"like":[12,80],"other":[13,346],"developing":[14],"countries":[15],"[1].":[16],"Modified":[17],"Jones":[18],"major":[19],"and":[20,40,42,49,84,100,328],"minor":[21],"criteria":[22],"with":[23,44,60,285,332],"recently":[24],"evidence":[25],"of":[26,58,67,110,194,217,226,244,253,270,294,313,350,372],"sore":[27,68],"throat":[28,38,69],"caused":[29],"by":[30,37,130,167,180],"group":[31,94,219,246,272,296,371],"A":[32,95],"streptococci":[33,61,70],"which":[34,114],"confirmed":[36],"culture":[39],"sensitivity":[41],"superadded":[43],"positive":[45,203,234,260,284],"streptococcal":[46,52,97],"antigen":[47],"test":[48,135,322,329],"raising":[50],"antibody":[53,179,355,365],"titre":[54],"use":[55],"for":[56,117,147,152,175,192,201,209,235,261,335],"diagnosis":[57],"infection":[59,98],"[2].":[62],"However,":[63],"some":[65],"cases":[66,77,361],"can":[71,324],"be":[72,233,259,283,325],"isolated,":[73],"so":[74],"such":[76],"several":[78],"antibodies":[79,315],"anti-streptolysin":[81],"O":[82,178,197,212,353],"(ASO)":[83,354],"anti-deoxyribonuclease":[85],"B":[86],"(DNase":[87],"B)":[88],"are":[89,115],"produced":[90],"response":[92],"to":[93,159,232,282],"beta-haemolytic":[96],"Material":[99],"method:":[101],"The":[102,186,311,348],"study":[103,358],"was":[104,128,141,280,362,367],"conducted":[105],"the":[107,118,145,157,176,345],"serology":[108,124],"laboratory":[109],"Microbiology":[111],"department,":[112],"samples":[113,158,172,189,205,222,229,249,256,275,299],"requested":[116],"ASO":[119,126,202,236,262,314,364],"investigation":[120],"were":[121,173,190,206,223,230,250,257,276,300],"received":[122],"laboratory.":[125],"testing":[127],"done":[129],"using":[131,168,181],"Rhelax-ASO":[132],"slide":[133],"agglutination":[134],"kit":[136,184],"from":[137],"BEACON":[138],"Diagnostics.":[139],"Serum":[140,163],"separated":[142,165],"out":[143,166,225,252],"subjecting":[144],"specimen":[146],"centrifugation":[148],"at":[149],"3000":[150],"rpm":[151],"5":[153],"minutes":[154],"after":[155],"allowing":[156],"get":[160],"fully":[161],"clotted.":[162],"then":[164],"micropipette.":[169],"Total":[170,199],"150":[171],"investigated":[174],"Anti-streptolysin":[177],"above":[182],"mentioned":[183],"Result:":[185],"250":[187],"serum":[188,204],"processed":[191],"detection":[193],"Anti":[195,210,351],"Streptolysin":[196,211],"antibodies.":[198,213],"prevalence":[200,238,264,286,349,366],"10":[207,298],"(4%)":[208],"In":[214,241,267,289],"(0-20)":[215],"years":[216,243,269,293],"age":[218,245,271,295,308,370],"total":[220,247,273,297,360],"120":[221],"received,":[224,251,301],"these":[227,254],"06":[228],"found":[231,258,281,305],"antibody,":[237,263],"rate":[239,265,287],"5%.":[240],"(21-40)":[242],"85":[248],"3":[255],"3.5%.":[266],"(41-60)":[268],"35":[274],"received;":[277],"01":[278],"sample":[279],"(2.8%).":[288],"more":[290],"than":[291],"60":[292],"no":[302],"any":[303],"positivity":[304],"this":[307,357],"group.":[309],"Conclusion:":[310],"estimation":[312],"simple,":[318],"cost-effective":[319],"way":[320],"&":[321],"report":[323],"given":[326],"rapidly":[327],"correlated":[331],"clinical":[333],"finding":[334],"routine":[336],"diagnostic":[337],"work.":[338],"It":[339],"useful":[341],"without":[342],"depending":[343],"upon":[344],"test.":[347],"streptolysin":[352],"among":[359],"4%.":[363],"higher":[368],"(0-20":[373],"years).":[374]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2025-10-10T00:00:00"}