{"id":"https://openalex.org/W4413019286","doi":"https://doi.org/10.1097/ms9.0000000000003571","title":"Advancements in endoscopic closure techniques for gastrointestinal luminal defects comparative perspectives on OTSC, endo suturing, TTS clips, and X-Tack","display_name":"Advancements in endoscopic closure techniques for gastrointestinal luminal defects comparative perspectives on OTSC, endo suturing, TTS clips, and X-Tack","publication_year":2025,"publication_date":"2025-07-16","ids":{"openalex":"https://openalex.org/W4413019286","doi":"https://doi.org/10.1097/ms9.0000000000003571","pmid":"https://pubmed.ncbi.nlm.nih.gov/40787569","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12333768"},"language":"en","primary_location":{"id":"doi:10.1097/ms9.0000000000003571","doi":"https://doi.org/10.1097/ms9.0000000000003571","is_oa":true,"landing_page_url":"https://doi.org/10.1097/ms9.0000000000003571","pdf_url":null,"source":{"id":"https://openalex.org/S4210226177","display_name":"Annals of Medicine and Surgery","issn_l":"2049-0801","issn":["2049-0801"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Medicine & Surgery","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1097/ms9.0000000000003571","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052403588","display_name":"Anmol Mohan","orcid":"https://orcid.org/0000-0002-8312-2884","observed_orcids":["https://orcid.org/0000-0002-8312-2884"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anmol Mohan","raw_affiliation_strings":["Department of Medicine, Mayo Clinic, Rochester, MN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Mayo Clinic, Rochester, MN, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011640189","display_name":"Mahesh Prasanth","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mahesh Prasanth","raw_affiliation_strings":["Department of Medicine, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Poland","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Namra Asif Saeed","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I25974024","display_name":"Baqai Medical University","ror":"https://ror.org/01v2x9m21","country_code":"PK","type":"education","lineage":["https://openalex.org/I25974024"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Namra Asif Saeed","raw_affiliation_strings":["Department of Medicine, Baqai Medical University, Karachi, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Baqai Medical University, Karachi, Pakistan","institution_ids":["https://openalex.org/I25974024"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5119232698","display_name":"Tusneem Shehzadi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I193670377","display_name":"University of Karachi","ror":"https://ror.org/05bbbc791","country_code":"PK","type":"education","lineage":["https://openalex.org/I193670377"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Tusneem Shehzadi","raw_affiliation_strings":["Department of Medicine, University College of medicine and dentistry, Karachi, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University College of medicine and dentistry, Karachi, Pakistan","institution_ids":["https://openalex.org/I193670377"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Zim Warda Hasan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I12097938","display_name":"West Virginia University","ror":"https://ror.org/011vxgd24","country_code":"US","type":"education","lineage":["https://openalex.org/I12097938"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zim Warda Hasan","raw_affiliation_strings":["Clinical and Translational Science, School of Medicine, West Virginia University, Morgantown, WV, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Translational Science, School of Medicine, West Virginia University, Morgantown, WV, USA","institution_ids":["https://openalex.org/I12097938"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Nasar Nasrullah Khan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334287468","display_name":"Nottingham University Hospitals NHS Trust","ror":"https://ror.org/05y3qh794","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1334287468"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nasar Nasrullah Khan","raw_affiliation_strings":["Department of Medicine, Nottingham University Hospital, Nottingham, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Nottingham University Hospital, Nottingham, UK","institution_ids":["https://openalex.org/I1334287468"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5099017828","display_name":"Dev Tanush","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I923305593","display_name":"Ziauddin University","ror":"https://ror.org/03vz8ns51","country_code":"PK","type":"education","lineage":["https://openalex.org/I923305593"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Dev Tanush","raw_affiliation_strings":["Department of Medicine, Ziauddin Medical University, Karachi, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Ziauddin Medical University, Karachi, Pakistan","institution_ids":["https://openalex.org/I923305593"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005449799","display_name":"Hasibullah Aminpoor","orcid":"https://orcid.org/0000-0003-1817-7800","observed_orcids":["https://orcid.org/0000-0003-1817-7800"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Hasibullah Aminpoor","raw_affiliation_strings":["Department of Medicine, Kabul, Afghanistan"],"raw_orcid":"https://orcid.org/0000-0003-1817-7800","affiliations":[{"raw_affiliation_string":"Department of Medicine, Kabul, Afghanistan","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5005449799"],"corresponding_institution_ids":[],"apc_list":{"value":1850,"currency":"USD","value_usd":1850},"apc_paid":{"value":1850,"currency":"USD","value_usd":1850},"fwci":0.9681,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.68522926,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"87","issue":"8","first_page":"5077","last_page":"5086"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11658","display_name":"Esophageal and GI Pathology","score":0.5185999870300293,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11658","display_name":"Esophageal and GI Pathology","score":0.5185999870300293,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11378","display_name":"Gastrointestinal Bleeding Diagnosis and Treatment","score":0.3959999978542328,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12053","display_name":"Minimally Invasive Surgical Techniques","score":0.03579999879002571,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/endoscopic-closure","display_name":"endoscopic closure","score":0.8840000033378601},{"id":"https://openalex.org/keywords/gastrointestinal-defects","display_name":"gastrointestinal defects","score":0.8040000200271606},{"id":"https://openalex.org/keywords/over-the-scope-clip","display_name":"over-the-scope clip","score":0.9679999947547913},{"id":"https://openalex.org/keywords/through-the-scope-clips","display_name":"through-the-scope clips","score":0.9869999885559082},{"id":"https://openalex.org/keywords/device-selection","display_name":"device selection","score":0.5210000276565552},{"id":"https://openalex.org/keywords/randomized-controlled-trials","display_name":"randomized controlled trials","score":0.7639999985694885}],"concepts":[{"id":"https://openalex.org/C2778739407","wikidata":"https://www.wikidata.org/wiki/Q165372","display_name":"CLIPS","level":2,"score":0.963093638420105},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8291324973106384},{"id":"https://openalex.org/C2778012447","wikidata":"https://www.wikidata.org/wiki/Q1034415","display_name":"Scope (computer science)","level":2,"score":0.7585867643356323},{"id":"https://openalex.org/C3019477240","wikidata":"https://www.wikidata.org/wiki/Q1755504","display_name":"Invasive surgery","level":2,"score":0.5183081030845642},{"id":"https://openalex.org/C2779974597","wikidata":"https://www.wikidata.org/wiki/Q28448986","display_name":"Clinical Practice","level":2,"score":0.4981117248535156},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.4766955077648163},{"id":"https://openalex.org/C146834321","wikidata":"https://www.wikidata.org/wiki/Q2979672","display_name":"Closure (psychology)","level":2,"score":0.47162699699401855},{"id":"https://openalex.org/C2989236134","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Patient care","level":2,"score":0.42541709542274475},{"id":"https://openalex.org/C160735492","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Health care","level":2,"score":0.4110097587108612},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.355283260345459},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2073577642440796},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.0825091302394867},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.06647476553916931},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C50522688","wikidata":"https://www.wikidata.org/wiki/Q189833","display_name":"Economic growth","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C34447519","wikidata":"https://www.wikidata.org/wiki/Q179522","display_name":"Market economy","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1097/ms9.0000000000003571","doi":"https://doi.org/10.1097/ms9.0000000000003571","is_oa":true,"landing_page_url":"https://doi.org/10.1097/ms9.0000000000003571","pdf_url":null,"source":{"id":"https://openalex.org/S4210226177","display_name":"Annals of Medicine and Surgery","issn_l":"2049-0801","issn":["2049-0801"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Medicine & Surgery","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12333768","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12333768","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ann Med Surg (Lond)","raw_type":"Text"},{"id":"pmid:40787569","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40787569","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of medicine and surgery (2012)","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1097/ms9.0000000000003571","doi":"https://doi.org/10.1097/ms9.0000000000003571","is_oa":true,"landing_page_url":"https://doi.org/10.1097/ms9.0000000000003571","pdf_url":null,"source":{"id":"https://openalex.org/S4210226177","display_name":"Annals of Medicine and Surgery","issn_l":"2049-0801","issn":["2049-0801"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Medicine & Surgery","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":97,"referenced_works":["https://openalex.org/W111311558","https://openalex.org/W1461652915","https://openalex.org/W1903286232","https://openalex.org/W1964633828","https://openalex.org/W1965816970","https://openalex.org/W1967655559","https://openalex.org/W1969335466","https://openalex.org/W1974894197","https://openalex.org/W1977466815","https://openalex.org/W1985558609","https://openalex.org/W1988967141","https://openalex.org/W1994481864","https://openalex.org/W2008843562","https://openalex.org/W2012756935","https://openalex.org/W2013844278","https://openalex.org/W2016288162","https://openalex.org/W2022226760","https://openalex.org/W2031338223","https://openalex.org/W2038233320","https://openalex.org/W2040589394","https://openalex.org/W2043057477","https://openalex.org/W2044449883","https://openalex.org/W2045123221","https://openalex.org/W2045276152","https://openalex.org/W2049940940","https://openalex.org/W2054909422","https://openalex.org/W2062481172","https://openalex.org/W2066205821","https://openalex.org/W2068194787","https://openalex.org/W2070942716","https://openalex.org/W2073247702","https://openalex.org/W2073718744","https://openalex.org/W2078449008","https://openalex.org/W2078815162","https://openalex.org/W2079347254","https://openalex.org/W2080081941","https://openalex.org/W2084610092","https://openalex.org/W2091589323","https://openalex.org/W2099566531","https://openalex.org/W2106506895","https://openalex.org/W2109536283","https://openalex.org/W2136490194","https://openalex.org/W2142162309","https://openalex.org/W2145668841","https://openalex.org/W2149968467","https://openalex.org/W2158675954","https://openalex.org/W2159449594","https://openalex.org/W2161387953","https://openalex.org/W2167196552","https://openalex.org/W2325612302","https://openalex.org/W2328701398","https://openalex.org/W2334674428","https://openalex.org/W2411873328","https://openalex.org/W2414378575","https://openalex.org/W2511103274","https://openalex.org/W2523489287","https://openalex.org/W2777619021","https://openalex.org/W2787795063","https://openalex.org/W2808761967","https://openalex.org/W2886887772","https://openalex.org/W2897031692","https://openalex.org/W2904096620","https://openalex.org/W2904231566","https://openalex.org/W2907949378","https://openalex.org/W2913111602","https://openalex.org/W2954435834","https://openalex.org/W2964182825","https://openalex.org/W2965028857","https://openalex.org/W2965432590","https://openalex.org/W2965920924","https://openalex.org/W2966836610","https://openalex.org/W2977541661","https://openalex.org/W2996895439","https://openalex.org/W2996957344","https://openalex.org/W3006235106","https://openalex.org/W3021896966","https://openalex.org/W3042424066","https://openalex.org/W3063495048","https://openalex.org/W3080114139","https://openalex.org/W3084035157","https://openalex.org/W3124517302","https://openalex.org/W3126301722","https://openalex.org/W3132763664","https://openalex.org/W3155094714","https://openalex.org/W3159909583","https://openalex.org/W3195538526","https://openalex.org/W3200116905","https://openalex.org/W3209202115","https://openalex.org/W3211386618","https://openalex.org/W4224940400","https://openalex.org/W4282927612","https://openalex.org/W4308061572","https://openalex.org/W4310949330","https://openalex.org/W4317877747","https://openalex.org/W4323306224","https://openalex.org/W4385462774","https://openalex.org/W6789636561"],"related_works":["https://openalex.org/W4412636619","https://openalex.org/W7164752445","https://openalex.org/W7119513337","https://openalex.org/W4396643030","https://openalex.org/W4416322383","https://openalex.org/W2982975729","https://openalex.org/W4416887745","https://openalex.org/W4367836225","https://openalex.org/W2515635664","https://openalex.org/W2942066636"],"abstract_inverted_index":{"Gastrointestinal":[0],"(GI)":[1],"defects":[2],"pose":[3],"a":[4],"significant":[5],"clinical":[6,62,72],"challenge,":[7],"impacting":[8],"patient":[9,126],"outcomes":[10,127],"and":[11,21,46,55,82,99,106,128],"healthcare":[12],"costs.":[13],"Endoscopic":[14],"closure":[15,114],"techniques":[16],"have":[17,67],"emerged":[18],"as":[19],"effective":[20],"minimally":[22],"invasive":[23],"approaches":[24],"to":[25,78,92,119,124],"manage":[26],"these":[27,65],"defects.":[28],"This":[29],"review":[30],"explores":[31],"the":[32,47,110,117],"various":[33],"endoscopic":[34,113],"techniques,":[35],"including":[36],"over-the-scope":[37],"clips":[38],"(OTSC),":[39],"endo":[40],"suturing":[41],"systems,":[42],"through-the-scope":[43],"(TTS)":[44],"clips,":[45],"X-Tack":[48],"system.":[49],"Each":[50],"technique":[51],"offers":[52],"distinct":[53],"advantages":[54],"limitations,":[56,109],"making":[57],"it":[58],"suitable":[59],"for":[60,96],"specific":[61],"scenarios.":[63],"While":[64],"devices":[66,115],"demonstrated":[68],"promising":[69],"results":[70],"in":[71],"practice,":[73],"further":[74],"research":[75,108],"is":[76],"needed":[77],"optimize":[79],"their":[80],"use":[81],"address":[83],"knowledge":[84],"gaps.":[85],"Large-scale":[86],"randomized":[87],"controlled":[88],"trials":[89],"are":[90],"essential":[91],"establish":[93],"evidence-based":[94],"guidelines":[95],"device":[97],"selection":[98],"procedural":[100],"techniques.":[101],"By":[102],"embracing":[103],"technological":[104],"advancements":[105],"addressing":[107],"field":[111],"of":[112],"has":[116],"potential":[118],"revolutionize":[120],"GI":[121],"care,":[122],"leading":[123],"improved":[125],"expanded":[129],"therapeutic":[130],"possibilities.":[131]},"counts_by_year":[{"year":2026,"cited_by_count":4}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2025-10-10T00:00:00"}