{"id":"https://openalex.org/W4413016014","doi":"https://doi.org/10.1016/j.neuroscience.2025.05.188","title":"Effects of exposure to micro/nanoplastics of polystyrene on neuronal oxidative stress, neuroinflammation, and anxiety-like behavior in mice","display_name":"Effects of exposure to micro/nanoplastics of polystyrene on neuronal oxidative stress, neuroinflammation, and anxiety-like behavior in mice","publication_year":2025,"publication_date":"2025-08-01","ids":{"openalex":"https://openalex.org/W4413016014","doi":"https://doi.org/10.1016/j.neuroscience.2025.05.188"},"language":"en","primary_location":{"id":"doi:10.1016/j.neuroscience.2025.05.188","doi":"https://doi.org/10.1016/j.neuroscience.2025.05.188","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.neuroscience.2025.05.188","pdf_url":null,"source":{"id":"https://openalex.org/S30122339","display_name":"Neuroscience","issn_l":"0306-4522","issn":["0306-4522","1873-7544"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5123420737","display_name":"Asmaa Lafram","orcid":"https://orcid.org/0009-0000-5496-8517","observed_orcids":["https://orcid.org/0009-0000-5496-8517"]},"institutions":[{"id":"https://openalex.org/I99297268","display_name":"University of Hassan II Casablanca","ror":"https://ror.org/001q4kn48","country_code":"MA","type":"education","lineage":["https://openalex.org/I99297268"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Lafram Asmaa","raw_affiliation_strings":["Physiopathology, Molecular Genetics and Biotechnology Laboratory, Health and Biotechnology Research Centre, Faculty of Sciences Ain Chock, University of Hassan II, Casablanca, Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Physiopathology, Molecular Genetics and Biotechnology Laboratory, Health and Biotechnology Research Centre, Faculty of Sciences Ain Chock, University of Hassan II, Casablanca, Morocco","institution_ids":["https://openalex.org/I99297268"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Krami Al Mehdi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I99297268","display_name":"University of Hassan II Casablanca","ror":"https://ror.org/001q4kn48","country_code":"MA","type":"education","lineage":["https://openalex.org/I99297268"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Krami Al Mehdi","raw_affiliation_strings":["Physiopathology, Molecular Genetics and Biotechnology Laboratory, Health and Biotechnology Research Centre, Faculty of Sciences Ain Chock, University of Hassan II, Casablanca, Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Physiopathology, Molecular Genetics and Biotechnology Laboratory, Health and Biotechnology Research Centre, Faculty of Sciences Ain Chock, University of Hassan II, Casablanca, Morocco","institution_ids":["https://openalex.org/I99297268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038400211","display_name":"Khadija Akarid","orcid":"https://orcid.org/0000-0003-2508-3116","observed_orcids":["https://orcid.org/0000-0003-2508-3116"]},"institutions":[{"id":"https://openalex.org/I99297268","display_name":"University of Hassan II Casablanca","ror":"https://ror.org/001q4kn48","country_code":"MA","type":"education","lineage":["https://openalex.org/I99297268"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Akarid Khadija","raw_affiliation_strings":["Health and Environment Laboratory, Biochemistry Biotechnology and Immunophysiopathology Research Team, Faculty of Sciences Ain Chock, University of Hassan II, Casablanca, Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Health and Environment Laboratory, Biochemistry Biotechnology and Immunophysiopathology Research Team, Faculty of Sciences Ain Chock, University of Hassan II, Casablanca, Morocco","institution_ids":["https://openalex.org/I99297268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087442154","display_name":"Jawad Laadraoui","orcid":"https://orcid.org/0000-0002-9784-1265","observed_orcids":["https://orcid.org/0000-0002-9784-1265"]},"institutions":[{"id":"https://openalex.org/I99297268","display_name":"University of Hassan II Casablanca","ror":"https://ror.org/001q4kn48","country_code":"MA","type":"education","lineage":["https://openalex.org/I99297268"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Laadraoui Jawad","raw_affiliation_strings":["Physiopathology, Molecular Genetics and Biotechnology Laboratory, Health and Biotechnology Research Centre, Faculty of Sciences Ain Chock, University of Hassan II, Casablanca, Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Physiopathology, Molecular Genetics and Biotechnology Laboratory, Health and Biotechnology Research Centre, Faculty of Sciences Ain Chock, University of Hassan II, Casablanca, Morocco","institution_ids":["https://openalex.org/I99297268"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5068823589","display_name":"Rachida Roky","orcid":"https://orcid.org/0000-0002-1118-7144","observed_orcids":["https://orcid.org/0000-0002-1118-7144"]},"institutions":[{"id":"https://openalex.org/I99297268","display_name":"University of Hassan II Casablanca","ror":"https://ror.org/001q4kn48","country_code":"MA","type":"education","lineage":["https://openalex.org/I99297268"]}],"countries":["MA"],"is_corresponding":false,"raw_author_name":"Roky Rachida","raw_affiliation_strings":["Physiopathology, Molecular Genetics and Biotechnology Laboratory, Health and Biotechnology Research Centre, Faculty of Sciences Ain Chock, University of Hassan II, Casablanca, Morocco"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Physiopathology, Molecular Genetics and Biotechnology Laboratory, Health and Biotechnology Research Centre, Faculty of Sciences Ain Chock, University of Hassan II, Casablanca, Morocco","institution_ids":["https://openalex.org/I99297268"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I99297268"],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.08466519,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"580","issue":null,"first_page":"13","last_page":"13"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10753","display_name":"Microplastics and Plastic Pollution","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10753","display_name":"Microplastics and Plastic Pollution","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10419","display_name":"Pharmaceutical and Antibiotic Environmental Impacts","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/polystyrene","display_name":"polystyrene","score":0.9340000152587891},{"id":"https://openalex.org/keywords/microplastics","display_name":"microplastics","score":0.9909999966621399},{"id":"https://openalex.org/keywords/nanoplastics","display_name":"nanoplastics","score":1.0},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.8930000066757202},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":1.0},{"id":"https://openalex.org/keywords/anxiety-like-behavior","display_name":"anxiety-like behavior","score":1.0},{"id":"https://openalex.org/keywords/neurotoxicity","display_name":"neurotoxicity","score":0.8619999885559082},{"id":"https://openalex.org/keywords/mice","display_name":"mice","score":0.4449999928474426},{"id":"https://openalex.org/keywords/plastic-pollution","display_name":"plastic pollution","score":0.578000009059906}],"concepts":[{"id":"https://openalex.org/C87753298","wikidata":"https://www.wikidata.org/wiki/Q17157137","display_name":"Neuroinflammation","level":3,"score":0.9115267992019653},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.8029296398162842},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.6345161199569702},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.46820786595344543},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3408341407775879},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.327134907245636},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.32348865270614624},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.24530813097953796},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.11604121327400208},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.11227619647979736}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.neuroscience.2025.05.188","doi":"https://doi.org/10.1016/j.neuroscience.2025.05.188","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.neuroscience.2025.05.188","pdf_url":null,"source":{"id":"https://openalex.org/S30122339","display_name":"Neuroscience","issn_l":"0306-4522","issn":["0306-4522","1873-7544"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-d","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuroscience","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6240000128746033,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4404630386","https://openalex.org/W4377090643","https://openalex.org/W4295954071","https://openalex.org/W4413864683","https://openalex.org/W4387817192","https://openalex.org/W4391685568","https://openalex.org/W7223102659","https://openalex.org/W4413962380","https://openalex.org/W7131354484","https://openalex.org/W7134193916"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2025-10-10T00:00:00"}