{"id":"https://openalex.org/W4412868280","doi":"https://doi.org/10.30526/37.4.3779","title":"Synthesis and Investigation The Biological Activity of Some New Alkenes Based on Thiazoldin-4-one Compounds","display_name":"Synthesis and Investigation The Biological Activity of Some New Alkenes Based on Thiazoldin-4-one Compounds","publication_year":2024,"publication_date":"2024-10-20","ids":{"openalex":"https://openalex.org/W4412868280","doi":"https://doi.org/10.30526/37.4.3779"},"language":"en","primary_location":{"id":"doi:10.30526/37.4.3779","doi":"https://doi.org/10.30526/37.4.3779","is_oa":true,"landing_page_url":"https://doi.org/10.30526/37.4.3779","pdf_url":"https://jih.uobaghdad.edu.iq/index.php/j/article/download/3779/2240","source":{"id":"https://openalex.org/S2764703235","display_name":"Ibn AL- Haitham Journal For Pure and Applied Science","issn_l":"1609-4042","issn":["1609-4042","2521-3407"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4310319170","host_organization_name":"University of Baghdad","host_organization_lineage":["https://openalex.org/P4310319170"],"host_organization_lineage_names":["University of Baghdad"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ibn AL-Haitham Journal For Pure and Applied Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://jih.uobaghdad.edu.iq/index.php/j/article/download/3779/2240","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041789534","display_name":"I. A. A. Hamdan","orcid":"https://orcid.org/0000-0003-4524-5303","observed_orcids":["https://orcid.org/0000-0003-4524-5303"]},"institutions":[{"id":"https://openalex.org/I135120706","display_name":"University of Baghdad","ror":"https://ror.org/007f1da21","country_code":"IQ","type":"education","lineage":["https://openalex.org/I135120706"]},{"id":"https://openalex.org/I501048437","display_name":"Al-Muthanna University","ror":"https://ror.org/03877wr45","country_code":"IQ","type":"education","lineage":["https://openalex.org/I501048437"]}],"countries":["IQ"],"is_corresponding":false,"raw_author_name":"Israa Abd Al Hassan Hamdan","raw_affiliation_strings":["Department of Biology, College of Education For Pure Science, Al- Muthanna University, Muthanna, Iraq and Department of Chemistry, College of Education For Pure Science (Ibn Al-Haitham), University of  Baghdad, Baghdad, Iraq"],"raw_orcid":"https://orcid.org/0000-0003-4524-5303","affiliations":[{"raw_affiliation_string":"Department of Biology, College of Education For Pure Science, Al- Muthanna University, Muthanna, Iraq and Department of Chemistry, College of Education For Pure Science (Ibn Al-Haitham), University of  Baghdad, Baghdad, Iraq","institution_ids":["https://openalex.org/I135120706","https://openalex.org/I501048437"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110745562","display_name":"Jumbad H. Tomma","orcid":"https://orcid.org/0000-0003-4625-8341","observed_orcids":["https://orcid.org/0000-0003-4625-8341"]},"institutions":[{"id":"https://openalex.org/I135120706","display_name":"University of Baghdad","ror":"https://ror.org/007f1da21","country_code":"IQ","type":"education","lineage":["https://openalex.org/I135120706"]}],"countries":["IQ"],"is_corresponding":false,"raw_author_name":"J. H. Tomma","raw_affiliation_strings":["Department of Chemistry, College of Education For Pure Science (Ibn Al-Haitham), University of  Baghdad, Baghdad, Iraq"],"raw_orcid":"https://orcid.org/0000-0003-4625-8341","affiliations":[{"raw_affiliation_string":"Department of Chemistry, College of Education For Pure Science (Ibn Al-Haitham), University of  Baghdad, Baghdad, Iraq","institution_ids":["https://openalex.org/I135120706"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":125000,"currency":"IQD","value_usd":null},"apc_paid":null,"fwci":0.2748,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.32029473,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"37","issue":"4","first_page":"273","last_page":"285"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12410","display_name":"Structural and Chemical Analysis of Organic and Inorganic Compounds","score":0.8417999744415283,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12410","display_name":"Structural and Chemical Analysis of Organic and Inorganic Compounds","score":0.8417999744415283,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10274","display_name":"Heterocyclic Compound Synthesis and Bioactivity","score":0.11779999732971191,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13160","display_name":"Synthesis and Biological Evaluation","score":0.010900000110268593,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/4-thiazolidinones","display_name":"4-thiazolidinones","score":0.843999981880188},{"id":"https://openalex.org/keywords/alkene-derivatives","display_name":"alkene derivatives","score":0.6840000152587891},{"id":"https://openalex.org/keywords/schiff-base","display_name":"Schiff base","score":0.8519999980926514},{"id":"https://openalex.org/keywords/1-3-4-oxadiazoles","display_name":"1,3,4-oxadiazoles","score":0.9760000109672546},{"id":"https://openalex.org/keywords/hydrazides","display_name":"hydrazides","score":0.9039999842643738},{"id":"https://openalex.org/keywords/antibacterial-activity","display_name":"antibacterial activity","score":0.9179999828338623},{"id":"https://openalex.org/keywords/staphylococcus-aureus","display_name":"Staphylococcus aureus","score":0.9520000219345093},{"id":"https://openalex.org/keywords/enterococcus-faecalis","display_name":"Enterococcus faecalis","score":0.9959999918937683},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.9900000095367432},{"id":"https://openalex.org/keywords/pseudomonas-aeruginosa","display_name":"Pseudomonas aeruginosa","score":0.9990000128746033},{"id":"https://openalex.org/keywords/main-protease","display_name":"main protease","score":0.8820000290870667},{"id":"https://openalex.org/keywords/molecular-docking","display_name":"molecular docking","score":0.8450000286102295},{"id":"https://openalex.org/keywords/heterocycle-synthesis","display_name":"heterocyclic synthesis","score":0.5590000152587891}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3705354332923889}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.30526/37.4.3779","doi":"https://doi.org/10.30526/37.4.3779","is_oa":true,"landing_page_url":"https://doi.org/10.30526/37.4.3779","pdf_url":"https://jih.uobaghdad.edu.iq/index.php/j/article/download/3779/2240","source":{"id":"https://openalex.org/S2764703235","display_name":"Ibn AL- Haitham Journal For Pure and Applied Science","issn_l":"1609-4042","issn":["1609-4042","2521-3407"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4310319170","host_organization_name":"University of Baghdad","host_organization_lineage":["https://openalex.org/P4310319170"],"host_organization_lineage_names":["University of Baghdad"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ibn AL-Haitham Journal For Pure and Applied Sciences","raw_type":"journal-article"},{"id":"pmh:oai:ojs2.jihcoed.com:article/3779","doi":null,"is_oa":true,"landing_page_url":"https://jih.uobaghdad.edu.iq/index.php/j/article/view/3779","pdf_url":null,"source":{"id":"https://openalex.org/S2764703235","display_name":"Ibn AL- Haitham Journal For Pure and Applied Science","issn_l":"1609-4042","issn":["1609-4042","2521-3407"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4310319170","host_organization_name":"University of Baghdad","host_organization_lineage":["https://openalex.org/P4310319170"],"host_organization_lineage_names":["University of Baghdad"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"1609-4042","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:4534c4c1a07145968b28e6ac3b474458","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/4534c4c1a07145968b28e6ac3b474458","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Ibn Al-Haitham Journal for Pure and Applied Sciences, Vol 37, Iss 4 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.30526/37.4.3779","doi":"https://doi.org/10.30526/37.4.3779","is_oa":true,"landing_page_url":"https://doi.org/10.30526/37.4.3779","pdf_url":"https://jih.uobaghdad.edu.iq/index.php/j/article/download/3779/2240","source":{"id":"https://openalex.org/S2764703235","display_name":"Ibn AL- Haitham Journal For Pure and Applied Science","issn_l":"1609-4042","issn":["1609-4042","2521-3407"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4310319170","host_organization_name":"University of Baghdad","host_organization_lineage":["https://openalex.org/P4310319170"],"host_organization_lineage_names":["University of Baghdad"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ibn AL-Haitham Journal For Pure and Applied Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320310603","display_name":"University of Baghdad","ror":"https://ror.org/007f1da21"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4412868280.pdf","grobid_xml":"https://content.openalex.org/works/W4412868280.grobid-xml"},"referenced_works_count":21,"referenced_works":["https://openalex.org/W2009005265","https://openalex.org/W2122013736","https://openalex.org/W2738414846","https://openalex.org/W2779629232","https://openalex.org/W2779797618","https://openalex.org/W2935142703","https://openalex.org/W2947270978","https://openalex.org/W2964969788","https://openalex.org/W2992038112","https://openalex.org/W3015199070","https://openalex.org/W3035451622","https://openalex.org/W3152716811","https://openalex.org/W3162145384","https://openalex.org/W3172291331","https://openalex.org/W4211161135","https://openalex.org/W4214596010","https://openalex.org/W4288740973","https://openalex.org/W4327911826","https://openalex.org/W4383377562","https://openalex.org/W4386035911","https://openalex.org/W4396517940"],"related_works":["https://openalex.org/W4280538241","https://openalex.org/W2052265331","https://openalex.org/W4409511444","https://openalex.org/W2181499291","https://openalex.org/W7099983787","https://openalex.org/W6912616971","https://openalex.org/W4225142588","https://openalex.org/W7155604771","https://openalex.org/W1850203417","https://openalex.org/W2469017983"],"abstract_inverted_index":{"This":[0],"work":[1],"has":[2],"been":[3],"done":[4],"to":[5,29,41,126],"prepare":[6,42],"a":[7,152],"series":[8],"of":[9,63,76,95,104,138],"new":[10],"alkene":[11],"compounds":[12,123],"derived":[13],"from":[14,67],"4-thiozolidinones":[15],"by":[16,166],"substituting":[17],"different":[18],"aldehydes,":[19],"P-acetamido-phenol,":[20],"and":[21,33,45,90,110,113,118],"2-mercapto-benzoimidazole,":[22],"which":[23,38,48,175],"were":[24,39,49,82],"used":[25,40,51],"as":[26],"starting":[27],"materials":[28],"form":[30],"ester":[31],"[I]a,b":[32],"then":[34,50],"make":[35],"hydrazides":[36],"[II]a,b,":[37],"1,":[43],"3,":[44],"4-oxadiazoles":[46],"[III]a,b,":[47],"for":[52,146],"prepared":[53,80,97],"Schiff":[54,68],"bases":[55],"[IV]a-f,":[56],"The":[57,70,92,121],"next":[58],"step":[59,72],"was":[60,73,99,144,162,176],"the":[61,74,79,96,139,157,167,171],"synthesis":[62,75,147],"4-thiazoldinone":[64],"derivatives":[65,81,98],"[V]a-f":[66],"bases.":[69],"final":[71,122],"alkenes":[77],"[VII]a-f,":[78],"identified":[83],"with":[84,156],"spectral":[85],"methods":[86],"(FT-IR,":[87],"1H-NMR,":[88],"mass,":[89],"CHNS).":[91],"antibacterial":[93],"activity":[94],"evaluated":[100],"against":[101,129,136],"four":[102],"types":[103],"bacteria,":[105,132],"positive":[106],"gram":[107,115],"(Staphylococcus":[108],"aureus":[109],"Enterococcus":[111,130],"faecalis.)":[112],"negative":[114],"(E.":[116],"coli":[117],"Pseudomonas":[119],"aerugionsa).":[120],"gave":[124],"high":[125,153],"moderate":[127],"efficacy":[128],"faecalis":[131],"molecular":[133],"modeling":[134],"study":[135],"one":[137],"SARS":[140],"human":[141],"coronavirus":[142],"proteins":[143],"tested":[145],"compounds.":[148],"Compound":[149],"[VII]c":[150],"had":[151],"bonding":[154,172],"strength":[155,173],"target":[158],"protein,":[159],"wherever":[160],"it":[161],"-8.08":[163],"Kcal/mole":[164],"followed":[165],"compound":[168],"[VII]a.":[169],"in":[170],"energy,":[174],"-7.65Kcal/mole.":[177]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2025-10-10T00:00:00"}