{"id":"https://openalex.org/W4412831770","doi":"https://doi.org/10.1101/2025.07.31.667987","title":"Concerted actions of distinct serotonin neurons orchestrate female pup care behavior","display_name":"Concerted actions of distinct serotonin neurons orchestrate female pup care behavior","publication_year":2025,"publication_date":"2025-08-01","ids":{"openalex":"https://openalex.org/W4412831770","doi":"https://doi.org/10.1101/2025.07.31.667987","pmid":"https://pubmed.ncbi.nlm.nih.gov/40766669","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12324472"},"language":"en","primary_location":{"id":"doi:10.1101/2025.07.31.667987","doi":"https://doi.org/10.1101/2025.07.31.667987","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2025.07.31.667987","pdf_url":null,"source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.1101/2025.07.31.667987","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056630146","display_name":"Shuyun Alina Xiao","orcid":"https://orcid.org/0009-0007-8208-7478","observed_orcids":["https://orcid.org/0009-0007-8208-7478"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shuyun Alina Xiao","raw_affiliation_strings":["Department of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA"],"raw_orcid":"https://orcid.org/0009-0007-8208-7478","affiliations":[{"raw_affiliation_string":"Department of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Che Cherry Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Che Cherry Chen","raw_affiliation_strings":["Department of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074287489","display_name":"Patricia M. Horvath","orcid":"https://orcid.org/0000-0001-9969-8637","observed_orcids":["https://orcid.org/0000-0001-9969-8637"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patricia Horvath","raw_affiliation_strings":["Department of Molecular and Cellular Biology, Howard Hughes Medical Institute, Center for Brain Science, Harvard University, Cambridge, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Cellular Biology, Howard Hughes Medical Institute, Center for Brain Science, Harvard University, Cambridge, MA, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043888856","display_name":"Valerie S. Tsai","orcid":"https://orcid.org/0000-0001-6003-717X","observed_orcids":["https://orcid.org/0000-0001-6003-717X"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Valerie Tsai","raw_affiliation_strings":["Department of Statistics, Wu Tsai Neurosciences Institute, Stanford University, CA, USA","Neurosciences Graduate Program, Stanford University, Stanford, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Statistics, Wu Tsai Neurosciences Institute, Stanford University, CA, USA","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Neurosciences Graduate Program, Stanford University, Stanford, CA, USA","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Vibiana Marie Cardenas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vibiana Marie Cardenas","raw_affiliation_strings":["Department of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071084322","display_name":"Dan Biderman","orcid":"https://orcid.org/0000-0003-2054-8439","observed_orcids":["https://orcid.org/0000-0003-2054-8439"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dan Biderman","raw_affiliation_strings":["Department of Computer Science, Stanford University, CA, USA","Department of Statistics, Wu Tsai Neurosciences Institute, Stanford University, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Stanford University, CA, USA","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Department of Statistics, Wu Tsai Neurosciences Institute, Stanford University, CA, USA","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101830334","display_name":"Fei Deng","orcid":"https://orcid.org/0000-0002-1997-4572","observed_orcids":["https://orcid.org/0000-0002-1997-4572"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4391768054","display_name":"State Key Laboratory of Membrane Biology","ror":"https://ror.org/03mq8q210","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I20231570","https://openalex.org/I4210167311","https://openalex.org/I4391768054","https://openalex.org/I99065089"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Fei Deng","raw_affiliation_strings":["Present address: Department of Neurosurgery, Wu Tsai Neurosciences Institute, Stanford University, CA, USA","State Key Laboratory of Membrane Biology, School of Life Sciences, Peking University, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Present address: Department of Neurosurgery, Wu Tsai Neurosciences Institute, Stanford University, CA, USA","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"State Key Laboratory of Membrane Biology, School of Life Sciences, Peking University, Beijing, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4391768054"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100428710","display_name":"Yulong Li","orcid":"https://orcid.org/0000-0002-9166-9919","observed_orcids":["https://orcid.org/0000-0002-9166-9919"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4391768054","display_name":"State Key Laboratory of Membrane Biology","ror":"https://ror.org/03mq8q210","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I20231570","https://openalex.org/I4210167311","https://openalex.org/I4391768054","https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yulong Li","raw_affiliation_strings":["State Key Laboratory of Membrane Biology, School of Life Sciences, Peking University, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Membrane Biology, School of Life Sciences, Peking University, Beijing, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4391768054"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054079047","display_name":"Scott W. Linderman","orcid":"https://orcid.org/0000-0002-3878-9073","observed_orcids":["https://orcid.org/0000-0002-3878-9073"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Scott Linderman","raw_affiliation_strings":["Department of Statistics, Wu Tsai Neurosciences Institute, Stanford University, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Statistics, Wu Tsai Neurosciences Institute, Stanford University, CA, USA","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089691588","display_name":"Catherine G. Dulac","orcid":"https://orcid.org/0000-0001-5024-5418","observed_orcids":["https://orcid.org/0000-0001-5024-5418"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Catherine Dulac","raw_affiliation_strings":["Department of Molecular and Cellular Biology, Howard Hughes Medical Institute, Center for Brain Science, Harvard University, Cambridge, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Cellular Biology, Howard Hughes Medical Institute, Center for Brain Science, Harvard University, Cambridge, MA, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019791073","display_name":"Liqun Luo","orcid":"https://orcid.org/0000-0001-5467-9264","observed_orcids":["https://orcid.org/0000-0001-5467-9264"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Liqun Luo","raw_affiliation_strings":["Department of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I97018004"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5019791073"],"corresponding_institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I97018004"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11541","display_name":"Neuroendocrine regulation and behavior","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/3207","display_name":"Social Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T11541","display_name":"Neuroendocrine regulation and behavior","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/3207","display_name":"Social Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/maternal-behavior","display_name":"maternal behavior","score":0.753000020980835},{"id":"https://openalex.org/keywords/pup-care","display_name":"pup care","score":0.9369999766349792},{"id":"https://openalex.org/keywords/serotonergic-neurons","display_name":"serotonergic neurons","score":0.9049999713897705},{"id":"https://openalex.org/keywords/medial-preoptic-area","display_name":"medial preoptic area","score":0.9760000109672546},{"id":"https://openalex.org/keywords/bed-nucleus-of-the-stria-terminalis","display_name":"bed nucleus of the stria terminalis","score":0.9980000257492065},{"id":"https://openalex.org/keywords/virgin-female-mice","display_name":"virgin female mice","score":0.6980000138282776},{"id":"https://openalex.org/keywords/lactating-women","display_name":"lactating women","score":0.7369999885559082},{"id":"https://openalex.org/keywords/reproductive-status","display_name":"reproductive status","score":0.5120000243186951},{"id":"https://openalex.org/keywords/serotonin-release","display_name":"serotonin release","score":0.5440000295639038},{"id":"https://openalex.org/keywords/social-behavior","display_name":"social behavior","score":0.5799999833106995},{"id":"https://openalex.org/keywords/neuromodulation","display_name":"neuromodulation","score":0.8009999990463257}],"concepts":[{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.7318747639656067},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6274600028991699},{"id":"https://openalex.org/C46312422","wikidata":"https://www.wikidata.org/wiki/Q11024","display_name":"Communication","level":1,"score":0.37794506549835205},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3774474561214447},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3728554844856262},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3073927164077759},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15310728549957275},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.05844461917877197}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.1101/2025.07.31.667987","doi":"https://doi.org/10.1101/2025.07.31.667987","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2025.07.31.667987","pdf_url":null,"source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"doi:10.21203/rs.3.rs-7134286/v1","doi":"https://doi.org/10.21203/rs.3.rs-7134286/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-7134286/v1","pdf_url":"https://www.researchsquare.com/article/rs-7134286/latest.pdf","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},{"id":"pmid:40766669","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40766669","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"bioRxiv : the preprint server for biology","raw_type":"Journal Article"},{"id":"pmid:40799751","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40799751","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Research square","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12324472","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12324472","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:12340915","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12340915","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Res Sq","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1101/2025.07.31.667987","doi":"https://doi.org/10.1101/2025.07.31.667987","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2025.07.31.667987","pdf_url":null,"source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.504800021648407,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5643505939","display_name":"Deconstructing the sertonin system in the mouse brain","funder_award_id":"1rf1ns131987-01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000891324","display_name":"Neuroscience Research Training","funder_award_id":"T32MH020016","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":59,"referenced_works":["https://openalex.org/W154919193","https://openalex.org/W1975355521","https://openalex.org/W1987332330","https://openalex.org/W2002975752","https://openalex.org/W2012597831","https://openalex.org/W2014738874","https://openalex.org/W2015243323","https://openalex.org/W2020460680","https://openalex.org/W2034710420","https://openalex.org/W2049613345","https://openalex.org/W2060357443","https://openalex.org/W2085900799","https://openalex.org/W2087453951","https://openalex.org/W2089210700","https://openalex.org/W2096790979","https://openalex.org/W2097110160","https://openalex.org/W2115955530","https://openalex.org/W2121311726","https://openalex.org/W2127567317","https://openalex.org/W2133287637","https://openalex.org/W2160133414","https://openalex.org/W2161853532","https://openalex.org/W2190061239","https://openalex.org/W2295231946","https://openalex.org/W2560473817","https://openalex.org/W2773803332","https://openalex.org/W2797465087","https://openalex.org/W2887114371","https://openalex.org/W2887399686","https://openalex.org/W2888526386","https://openalex.org/W2892296638","https://openalex.org/W2899224111","https://openalex.org/W2921903746","https://openalex.org/W2930394955","https://openalex.org/W2953204260","https://openalex.org/W2967535576","https://openalex.org/W2982239238","https://openalex.org/W3010882950","https://openalex.org/W3021105102","https://openalex.org/W3022214373","https://openalex.org/W3041179078","https://openalex.org/W3083278519","https://openalex.org/W3139194100","https://openalex.org/W3202576321","https://openalex.org/W4207083621","https://openalex.org/W4211248987","https://openalex.org/W4282542764","https://openalex.org/W4322767145","https://openalex.org/W4379645230","https://openalex.org/W4384826532","https://openalex.org/W4387392263","https://openalex.org/W4387825819","https://openalex.org/W4392460427","https://openalex.org/W4392796856","https://openalex.org/W4400007726","https://openalex.org/W4400729541","https://openalex.org/W4401611147","https://openalex.org/W4408217872","https://openalex.org/W4410019186"],"related_works":["https://openalex.org/W6965258472","https://openalex.org/W7158987747","https://openalex.org/W2138956837","https://openalex.org/W4324093950","https://openalex.org/W4379645230","https://openalex.org/W4384826532","https://openalex.org/W3139194100","https://openalex.org/W2027705545","https://openalex.org/W4409799532","https://openalex.org/W2077405687"],"abstract_inverted_index":{"Abstract":[0],"In":[1,116,137],"many":[2],"mammalian":[3],"species,":[4],"female":[5,85,118],"behavior":[6,104],"towards":[7,32],"infant":[8],"conspecifics":[9],"changes":[10,197],"across":[11,198],"reproductive":[12,183],"stages.":[13,200],"Sexually":[14],"na\u00efve":[15],"females":[16,110],"interact":[17],"minimally":[18],"or":[19,95,158],"aggressively":[20],"with":[21],"infants,":[22,34],"whereas":[23,68],"the":[24,58,72,76,120,161],"same":[25],"animals":[26],"exhibit":[27],"extensive":[28],"care":[29,65],"behavior,":[30],"even":[31],"unrelated":[33],"after":[35],"parturition1\u20136.":[36],"Here,":[37],"we":[38],"discovered":[39],"that":[40,106,112],"two":[41],"distinct":[42,173],"sets":[43],"of":[44,75,92,113,151],"serotonin":[45,88,128,139,152,174],"neurons":[46,55],"collectively":[47],"mediate":[48],"this":[49],"dramatic":[50],"transition":[51],"in":[52,66,83,90,127,130,135,144,155,164],"maternal":[53],"behavior\u2014serotonin":[54],"projecting":[56,70],"to":[57,71,101],"medial":[59],"preoptic":[60],"area":[61],"(mPOA)":[62],"promote":[63],"pup":[64,81,122,147,165],"mothers,":[67,138],"those":[69],"bed":[73],"nucleus":[74],"stria":[77],"terminalis":[78],"(BNST)":[79],"suppress":[80],"interaction":[82,123],"virgin":[84,109,117],"mice.":[86],"Disrupting":[87],"synthesis":[89],"either":[91,97,156],"these":[93,168],"subpopulations":[94,175],"stimulating":[96],"subpopulation":[98],"is":[99],"sufficient":[100],"toggle":[102],"pup-directed":[103],"between":[105],"displayed":[107],"by":[108],"and":[111,185],"lactating":[114],"mothers.":[115],"mice,":[119],"first":[121],"triggers":[124],"an":[125],"increase":[126],"release":[129],"BNST":[131,159],"but":[132],"a":[133,181,187,192],"decrease":[134],"mPOA.":[136],"activity":[140],"becomes":[141],"greatly":[142],"elevated":[143],"mPOA":[145,157],"during":[146],"interactions.":[148],"Acute":[149],"interruption":[150],"signaling":[153],"locally":[154],"disrupts":[160],"stage-dependent":[162],"switch":[163],"care.":[166],"Together,":[167],"results":[169],"highlight":[170],"how":[171,191],"functionally":[172],"orchestrate":[176],"social":[177],"behaviors":[178],"appropriate":[179],"for":[180,190],"given":[182],"state,":[184],"suggest":[186],"circuit":[188],"logic":[189],"neuromodulator":[193],"coordinates":[194],"adaptive":[195],"behavioral":[196],"life":[199]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2025-10-10T00:00:00"}
