{"id":"https://openalex.org/W4412809482","doi":"https://doi.org/10.5152/neuropsychiatricinvest.2023.23007","title":"Mediating Effect of Sex-Related Differences in the Relationship Between Cognitive Functioning and Clinical Symptoms in Patients with Schizophrenia","display_name":"Mediating Effect of Sex-Related Differences in the Relationship Between Cognitive Functioning and Clinical Symptoms in Patients with Schizophrenia","publication_year":2024,"publication_date":"2024-01-10","ids":{"openalex":"https://openalex.org/W4412809482","doi":"https://doi.org/10.5152/neuropsychiatricinvest.2023.23007"},"language":"en","primary_location":{"id":"doi:10.5152/neuropsychiatricinvest.2023.23007","doi":"https://doi.org/10.5152/neuropsychiatricinvest.2023.23007","is_oa":true,"landing_page_url":"https://doi.org/10.5152/neuropsychiatricinvest.2023.23007","pdf_url":"https://neuropsychiatricinvestigation.org/index.php/pub/article/view/1085/1085","source":{"id":"https://openalex.org/S4386622102","display_name":"Neuropsychiatric Investigation","issn_l":"2792-0070","issn":["2792-0070"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-4","tr-dizin"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuropsychiatric Investigation","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://neuropsychiatricinvestigation.org/index.php/pub/article/view/1085/1085","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028153138","display_name":"T. A. Lepilkina","orcid":"https://orcid.org/0000-0002-2640-4658","observed_orcids":["https://orcid.org/0000-0002-2640-4658"]},"institutions":[{"id":"https://openalex.org/I4210153069","display_name":"Mental Health Research Center of Russian Academy of Medical Sciences","ror":"https://ror.org/055csed06","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110862","https://openalex.org/I4210153069"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Taissia A Lepilkina","raw_affiliation_strings":["Laboratory of Psychopharmacology, Mental Health Research Center, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Psychopharmacology, Mental Health Research Center, Moscow, Russia","institution_ids":["https://openalex.org/I4210153069"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017247312","display_name":"Morozova Ma","orcid":"https://orcid.org/0000-0002-7847-2716","observed_orcids":["https://orcid.org/0000-0002-7847-2716"]},"institutions":[{"id":"https://openalex.org/I4210153069","display_name":"Mental Health Research Center of Russian Academy of Medical Sciences","ror":"https://ror.org/055csed06","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110862","https://openalex.org/I4210153069"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Margarita A Morozova","raw_affiliation_strings":["Laboratory of Psychopharmacology, Mental Health Research Center, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Psychopharmacology, Mental Health Research Center, Moscow, Russia","institution_ids":["https://openalex.org/I4210153069"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112588546","display_name":"Andrey A. Alekseev","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210153069","display_name":"Mental Health Research Center of Russian Academy of Medical Sciences","ror":"https://ror.org/055csed06","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110862","https://openalex.org/I4210153069"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Andrey a Alekseev","raw_affiliation_strings":["Laboratory of Psychopharmacology, Mental Health Research Center, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Psychopharmacology, Mental Health Research Center, Moscow, Russia","institution_ids":["https://openalex.org/I4210153069"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210153069"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"61","issue":"4","first_page":"110","last_page":"116"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12308","display_name":"Mental Health and Psychiatry","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1211","display_name":"Philosophy"},"field":{"id":"https://openalex.org/fields/12","display_name":"Arts and Humanities"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/schizophrenia","display_name":"schizophrenia","score":0.9959999918937683},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.9520000219345093},{"id":"https://openalex.org/keywords/cognitive-function","display_name":"cognitive function","score":0.9660000205039978},{"id":"https://openalex.org/keywords/symptoms","display_name":"clinical symptoms","score":0.9769999980926514},{"id":"https://openalex.org/keywords/paranoid-schizophrenia","display_name":"paranoid schizophrenia","score":0.7609999775886536},{"id":"https://openalex.org/keywords/executive-function","display_name":"executive function","score":0.5569999814033508},{"id":"https://openalex.org/keywords/psychomotor-speed","display_name":"psychomotor speed","score":0.9959999918937683},{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"cognitive impairment","score":0.42800000309944153},{"id":"https://openalex.org/keywords/symptom-severity","display_name":"symptom severity","score":0.5799999833106995},{"id":"https://openalex.org/keywords/remission","display_name":"remission","score":0.5040000081062317}],"concepts":[{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.8385909795761108},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.585943341255188},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.5787550806999207},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.5707283616065979},{"id":"https://openalex.org/C134290984","wikidata":"https://www.wikidata.org/wiki/Q5141241","display_name":"Cognitive skill","level":3,"score":0.48187264800071716},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.32436516880989075},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.3158460259437561}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.5152/neuropsychiatricinvest.2023.23007","doi":"https://doi.org/10.5152/neuropsychiatricinvest.2023.23007","is_oa":true,"landing_page_url":"https://doi.org/10.5152/neuropsychiatricinvest.2023.23007","pdf_url":"https://neuropsychiatricinvestigation.org/index.php/pub/article/view/1085/1085","source":{"id":"https://openalex.org/S4386622102","display_name":"Neuropsychiatric Investigation","issn_l":"2792-0070","issn":["2792-0070"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-4","tr-dizin"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuropsychiatric Investigation","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.5152/neuropsychiatricinvest.2023.23007","doi":"https://doi.org/10.5152/neuropsychiatricinvest.2023.23007","is_oa":true,"landing_page_url":"https://doi.org/10.5152/neuropsychiatricinvest.2023.23007","pdf_url":"https://neuropsychiatricinvestigation.org/index.php/pub/article/view/1085/1085","source":{"id":"https://openalex.org/S4386622102","display_name":"Neuropsychiatric Investigation","issn_l":"2792-0070","issn":["2792-0070"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-4","tr-dizin"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neuropsychiatric Investigation","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4412809482.pdf","grobid_xml":"https://content.openalex.org/works/W4412809482.grobid-xml"},"referenced_works_count":22,"referenced_works":["https://openalex.org/W572447838","https://openalex.org/W1989115002","https://openalex.org/W1990624530","https://openalex.org/W1994743726","https://openalex.org/W2005690231","https://openalex.org/W2035528776","https://openalex.org/W2121981305","https://openalex.org/W2142355730","https://openalex.org/W2157863535","https://openalex.org/W2164576666","https://openalex.org/W2169768531","https://openalex.org/W2465388719","https://openalex.org/W2470008858","https://openalex.org/W2519830121","https://openalex.org/W2754537451","https://openalex.org/W2883684980","https://openalex.org/W2902106411","https://openalex.org/W2979594329","https://openalex.org/W3083900586","https://openalex.org/W3090293687","https://openalex.org/W4205493262","https://openalex.org/W6835422082"],"related_works":["https://openalex.org/W3083900586","https://openalex.org/W2413930378","https://openalex.org/W2142355730","https://openalex.org/W2026443895","https://openalex.org/W2133480690","https://openalex.org/W2025054198","https://openalex.org/W3135778841","https://openalex.org/W2112376007","https://openalex.org/W2130391708","https://openalex.org/W4405617657"],"abstract_inverted_index":{"Objective:":[0],"Sex":[1],"differences":[2,235],"in":[3,72,117,137,141,157,166,236,245],"patients":[4,65,114,153,162,246],"suffering":[5],"from":[6],"schizophrenia":[7,71],"are":[8,34],"well":[9],"established":[10],"for":[11,22,179],"clinical":[12,32,150,202,243],"symptoms":[13,33,244],"and":[14,31,46,63,85,103,107,112,127,140,149,216,242],"a":[15,90,134,210],"number":[16],"of":[17,54,57,78,83,93,120,124,129,144,169,181,204,219,233],"sociodemographic":[18],"parameters,":[19],"but":[20],"not":[21],"cognitive":[23,43,94,138,147,185,214,240],"functioning.":[24,171],"Data":[25],"on":[26],"the":[27,47,55,58,79,101,125,142,182,193,201,217,237],"relationship":[28,48,238],"between":[29,49,146,239],"cognition":[30],"also":[35],"contradictory.":[36],"This":[37],"study":[38],"was":[39,98,177],"aimed":[40],"at":[41],"evaluating":[42],"functions,":[44],"symptomatology,":[45],"these":[50],"domains,":[51],"with":[52,69,200,247],"consideration":[53],"sex":[56,208],"patient.":[59],"Methods:":[60],"\u041ene":[61],"hundred":[62],"twenty-nine":[64],"(55%":[66],"males)":[67],"diagnosed":[68],"paranoid":[70],"remission":[73],"according":[74],"to":[75,192],"10th":[76],"revision":[77],"International":[80],"Statistical":[81],"Classification":[82],"Diseases":[84],"Related":[86],"Health":[87],"Problems":[88],"completed":[89],"broad":[91],"battery":[92],"tests.":[95],"Disease":[96],"severity":[97,128],"measured":[99],"by":[100],"Positive":[102],"Negative":[104],"Syndrome":[105],"Scale":[106],"Clinical":[108],"Global":[109],"Impression\u2014Severity.":[110],"Male":[111],"female":[113],"were":[115,188,196],"homogeneous":[116],"age,":[118],"age":[119],"illness":[121],"onset,":[122],"duration":[123],"disease,":[126],"symptomatology.":[130],"Results:":[131],"Patients":[132],"showed":[133,163],"notable":[135],"difference":[136,176],"functioning":[139,148,215,241],"pattern":[143],"links":[145],"symptoms.":[151],"Female":[152],"demonstrated":[154],"higher":[155,164],"results":[156,165],"psychomotor":[158],"speed,":[159],"while":[160],"male":[161],"some":[167],"aspects":[168],"executive":[170],"The":[172],"most":[173],"prominent":[174],"sex-related":[175,234],"that":[178,187],"each":[180],"sexes,":[183],"those":[184],"functions":[186],"more":[189,198],"impaired":[190],"relative":[191],"group":[194],"trend":[195],"associated":[197],"closely":[199],"symptomatology":[203,218],"schizophrenia.":[205,220,248],"Conclusion:":[206],"Patients\u2019":[207],"is":[209],"crucial":[211],"factor":[212],"mediating":[213],"Cite":[221],"this":[222],"article":[223],"as:":[224],"Lepilkina":[225],"TA,":[226],"Morozova":[227],"MA,":[228],"Alekseev":[229],"AA.":[230],"Mediating":[231],"effect":[232],"Neuropsychiatr":[249],"Invest.":[250],"2023;61(4):110-116.":[251]},"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}
