{"id":"https://openalex.org/W4412529153","doi":"https://doi.org/10.1016/j.parkreldis.2025.107968","title":"Cause of death for patients who present with primary progressive apraxia of speech","display_name":"Cause of death for patients who present with primary progressive apraxia of speech","publication_year":2025,"publication_date":"2025-07-21","ids":{"openalex":"https://openalex.org/W4412529153","doi":"https://doi.org/10.1016/j.parkreldis.2025.107968","pmid":"https://pubmed.ncbi.nlm.nih.gov/40706471","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12349914"},"language":"en","primary_location":{"id":"doi:10.1016/j.parkreldis.2025.107968","doi":"https://doi.org/10.1016/j.parkreldis.2025.107968","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.parkreldis.2025.107968","pdf_url":null,"source":{"id":"https://openalex.org/S147691530","display_name":"Parkinsonism & Related Disorders","issn_l":"1353-8020","issn":["1353-8020","1873-5126"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Parkinsonism & Related Disorders","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/j.parkreldis.2025.107968","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031615915","display_name":"Rene L. Utianski","orcid":"https://orcid.org/0000-0001-9519-1302","observed_orcids":["https://orcid.org/0000-0001-9519-1302"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Rene L. Utianski","raw_affiliation_strings":["Department of Neurology, Mayo Clinic, Rochester, MN, USA. Electronic address: Utianski.Rene@Mayo.edu"],"raw_orcid":"https://orcid.org/0000-0001-9519-1302","affiliations":[{"raw_affiliation_string":"Department of Neurology, Mayo Clinic, Rochester, MN, USA. Electronic address: Utianski.Rene@Mayo.edu","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024058782","display_name":"Gabriela F. Meade","orcid":"https://orcid.org/0000-0001-6153-7782","observed_orcids":["https://orcid.org/0000-0001-6153-7782"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gabriela Meade","raw_affiliation_strings":["Department of Neurology, Mayo Clinic, Rochester, MN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Mayo Clinic, Rochester, MN, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005285557","display_name":"Joseph R. Duffy","orcid":"https://orcid.org/0000-0001-8206-3432","observed_orcids":["https://orcid.org/0000-0001-8206-3432"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph R. Duffy","raw_affiliation_strings":["Department of Neurology, Mayo Clinic, Rochester, MN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Mayo Clinic, Rochester, MN, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089364426","display_name":"Sarah M. Boland","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sarah Boland","raw_affiliation_strings":["Department of Neurology, Mayo Clinic, Rochester, MN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Mayo Clinic, Rochester, MN, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089684856","display_name":"Jennifer Louise Whitwell","orcid":"https://orcid.org/0000-0001-6914-1563","observed_orcids":["https://orcid.org/0000-0001-6914-1563"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jennifer L. Whitwell","raw_affiliation_strings":["Department of Radiology, Mayo Clinic, Rochester, MN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Mayo Clinic, Rochester, MN, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046855704","display_name":"Hugo Botha","orcid":"https://orcid.org/0000-0003-4390-685X","observed_orcids":["https://orcid.org/0000-0003-4390-685X"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hugo Botha","raw_affiliation_strings":["Department of Neurology, Mayo Clinic, Rochester, MN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Mayo Clinic, Rochester, MN, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007824103","display_name":"Keith A. Josephs","orcid":"https://orcid.org/0000-0003-2930-8634","observed_orcids":["https://orcid.org/0000-0003-2930-8634"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Keith A. Josephs","raw_affiliation_strings":["Department of Neurology, Mayo Clinic, Rochester, MN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Mayo Clinic, Rochester, MN, USA","institution_ids":["https://openalex.org/I1330342723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5031615915"],"corresponding_institution_ids":["https://openalex.org/I1330342723"],"apc_list":{"value":3460,"currency":"USD","value_usd":3460},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.16931259,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"138","issue":null,"first_page":"107968","last_page":"107968"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.6654999852180481,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.6654999852180481,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.2142000049352646,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10855","display_name":"Amyotrophic Lateral Sclerosis Research","score":0.027000000700354576,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/primary-progressive-apraxia-of-speech","display_name":"primary progressive apraxia of speech","score":0.9980000257492065},{"id":"https://openalex.org/keywords/causes-of-death","display_name":"causes of death","score":0.9079999923706055}],"concepts":[{"id":"https://openalex.org/C2779140760","wikidata":"https://www.wikidata.org/wiki/Q18767","display_name":"Primary progressive aphasia","level":5,"score":0.8081458806991577},{"id":"https://openalex.org/C2776818353","wikidata":"https://www.wikidata.org/wiki/Q498916","display_name":"Apraxia","level":3,"score":0.7832062244415283},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.5257160067558289},{"id":"https://openalex.org/C2777977315","wikidata":"https://www.wikidata.org/wiki/Q7243056","display_name":"Primary (astronomy)","level":2,"score":0.49828076362609863},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.49680450558662415},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.39697369933128357},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.12724721431732178},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.10336878895759583},{"id":"https://openalex.org/C2779422653","wikidata":"https://www.wikidata.org/wiki/Q2836","display_name":"Aphasia","level":2,"score":0.0878949761390686},{"id":"https://openalex.org/C2778641062","wikidata":"https://www.wikidata.org/wiki/Q18592","display_name":"Frontotemporal dementia","level":4,"score":0.08621394634246826},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.08279624581336975},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.07460933923721313},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C1276947","wikidata":"https://www.wikidata.org/wiki/Q333","display_name":"Astronomy","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001072","descriptor_name":"Apraxias","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D002423","descriptor_name":"Cause of Death","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003680","descriptor_name":"Deglutition Disorders","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D003680","descriptor_name":"Deglutition Disorders","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013064","descriptor_name":"Speech Disorders","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.parkreldis.2025.107968","doi":"https://doi.org/10.1016/j.parkreldis.2025.107968","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.parkreldis.2025.107968","pdf_url":null,"source":{"id":"https://openalex.org/S147691530","display_name":"Parkinsonism & Related Disorders","issn_l":"1353-8020","issn":["1353-8020","1873-5126"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Parkinsonism & Related Disorders","raw_type":"journal-article"},{"id":"pmid:40706471","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40706471","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Parkinsonism & related disorders","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12349914","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12349914/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Parkinsonism Relat Disord","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/j.parkreldis.2025.107968","doi":"https://doi.org/10.1016/j.parkreldis.2025.107968","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.parkreldis.2025.107968","pdf_url":null,"source":{"id":"https://openalex.org/S147691530","display_name":"Parkinsonism & Related Disorders","issn_l":"1353-8020","issn":["1353-8020","1873-5126"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Parkinsonism & Related Disorders","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G1974218536","display_name":"Automated speech assessment for diagnosis of FTD spectrum disorders","funder_award_id":"1r01ag083832-01a1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5446874454","display_name":null,"funder_award_id":"R01-AG083832","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G9000867030","display_name":"The neurobiology of two distinct subtypes of neurodegenerative apraxia of speech: phenotypes of Alzheimer disease related 4-repeat tauopathies","funder_award_id":"R01DC014942","funder_id":"https://openalex.org/F4320337352","funder_display_name":"National Institute on Deafness and Other Communication Disorders"},{"id":"https://openalex.org/G9000906195","display_name":"Longitudinal multi-modality imaging in non-fluent/agrammatic primary progressive aphasia","funder_award_id":"R01DC012519","funder_id":"https://openalex.org/F4320337352","funder_display_name":"National Institute on Deafness and Other Communication Disorders"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337352","display_name":"National Institute on Deafness and Other Communication Disorders","ror":"https://ror.org/04mhx6838"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W575931326","https://openalex.org/W1878285885","https://openalex.org/W2018070977","https://openalex.org/W2059625526","https://openalex.org/W2097835289","https://openalex.org/W2103224436","https://openalex.org/W2138190873","https://openalex.org/W2268134926","https://openalex.org/W2938112926","https://openalex.org/W3118777027","https://openalex.org/W3159757480","https://openalex.org/W3173062894","https://openalex.org/W3193548447","https://openalex.org/W4200432901","https://openalex.org/W4386016305","https://openalex.org/W4388448227","https://openalex.org/W4390267830","https://openalex.org/W4409735713"],"related_works":["https://openalex.org/W7117310809","https://openalex.org/W4409735713","https://openalex.org/W4409237339","https://openalex.org/W3103553227","https://openalex.org/W3081949820","https://openalex.org/W2890326191","https://openalex.org/W3040588454","https://openalex.org/W4407893623","https://openalex.org/W3092380486","https://openalex.org/W168328184"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2025-10-10T00:00:00"}