{"id":"https://openalex.org/W4412527593","doi":"https://doi.org/10.69667/rmj.25306","title":"Prevalence of Carbapenem-Resistant Enterobacteriaceae Isolated from Clinical Samples in Medical Tobruk Center","display_name":"Prevalence of Carbapenem-Resistant Enterobacteriaceae Isolated from Clinical Samples in Medical Tobruk Center","publication_year":2025,"publication_date":"2025-07-20","ids":{"openalex":"https://openalex.org/W4412527593","doi":"https://doi.org/10.69667/rmj.25306"},"language":"en","primary_location":{"id":"doi:10.69667/rmj.25306","doi":"https://doi.org/10.69667/rmj.25306","is_oa":true,"landing_page_url":"https://doi.org/10.69667/rmj.25306","pdf_url":"https://razi.edu.ly/rmj/index.php/hm/article/download/26/22","source":{"id":"https://openalex.org/S5407054572","display_name":"Razi Medical Journal","issn_l":"3080-3624","issn":["3080-3624"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Razi Medical Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://razi.edu.ly/rmj/index.php/hm/article/download/26/22","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5119026994","display_name":"Laila Alfageih","orcid":"https://orcid.org/0009-0009-8965-4572","observed_orcids":["https://orcid.org/0009-0009-8965-4572"]},"institutions":[{"id":"https://openalex.org/I4210161365","display_name":"Libyan Academy","ror":"https://ror.org/05s3qq987","country_code":"LY","type":"education","lineage":["https://openalex.org/I4210161365"]},{"id":"https://openalex.org/I4401200284","display_name":"Tobruk University","ror":"https://ror.org/017mqhz69","country_code":null,"type":"education","lineage":["https://openalex.org/I4401200284"]}],"countries":["LY"],"is_corresponding":true,"raw_author_name":"Laila Alfageih","raw_affiliation_strings":["Libyan Academy for Postgraduate Studies, Tobruk Branch, Libya. Department of Medical Science, Faculty of Dentistry, Tobruk University, Tobruk, Libya"],"raw_orcid":"https://orcid.org/0009-0009-8965-4572","affiliations":[{"raw_affiliation_string":"Libyan Academy for Postgraduate Studies, Tobruk Branch, Libya. Department of Medical Science, Faculty of Dentistry, Tobruk University, Tobruk, Libya","institution_ids":["https://openalex.org/I4210161365","https://openalex.org/I4401200284"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5119026994"],"corresponding_institution_ids":["https://openalex.org/I4210161365","https://openalex.org/I4401200284"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.10648548,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"126","last_page":"136"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10897","display_name":"Antibiotic Use and Resistance","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11000","display_name":"Infection Control in Healthcare","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/carbapenem-resistant-enterobacteriaceae","display_name":"carbapenem-resistant Enterobacteriaceae","score":0.9950000047683716},{"id":"https://openalex.org/keywords/carbapenem-resistance","display_name":"carbapenem resistance","score":0.8960000276565552},{"id":"https://openalex.org/keywords/intensive-care-unit","display_name":"intensive care unit","score":0.753000020980835},{"id":"https://openalex.org/keywords/klebsiella-pneumoniae","display_name":"Klebsiella pneumoniae","score":0.8999999761581421},{"id":"https://openalex.org/keywords/acinetobacter-baumannii","display_name":"Acinetobacter baumannii","score":0.9990000128746033},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.8960000276565552},{"id":"https://openalex.org/keywords/carbapenemase-production","display_name":"carbapenemase production","score":0.8730000257492065},{"id":"https://openalex.org/keywords/ertapenem","display_name":"ertapenem","score":0.7820000052452087},{"id":"https://openalex.org/keywords/imipenem","display_name":"imipenem","score":0.9369999766349792},{"id":"https://openalex.org/keywords/meropenem","display_name":"meropenem","score":0.9980000257492065},{"id":"https://openalex.org/keywords/antimicrobial-susceptibility","display_name":"antimicrobial susceptibility","score":0.7720000147819519},{"id":"https://openalex.org/keywords/healthcare-workers","display_name":"healthcare workers","score":0.6110000014305115},{"id":"https://openalex.org/keywords/environmental-surfaces","display_name":"environmental surfaces","score":0.652999997138977},{"id":"https://openalex.org/keywords/nosocomial-infections","display_name":"nosocomial infections","score":0.6320000290870667}],"concepts":[{"id":"https://openalex.org/C2778910516","wikidata":"https://www.wikidata.org/wiki/Q380136","display_name":"Enterobacteriaceae","level":4,"score":0.8071198463439941},{"id":"https://openalex.org/C2775992322","wikidata":"https://www.wikidata.org/wiki/Q5037837","display_name":"Carbapenem-resistant enterobacteriaceae","level":5,"score":0.7862686514854431},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.6333732604980469},{"id":"https://openalex.org/C2776685102","wikidata":"https://www.wikidata.org/wiki/Q410897","display_name":"Carbapenem","level":3,"score":0.6006205677986145},{"id":"https://openalex.org/C2779463800","wikidata":"https://www.wikidata.org/wiki/Q5062222","display_name":"Center (category theory)","level":2,"score":0.5341784954071045},{"id":"https://openalex.org/C2910948552","wikidata":"https://www.wikidata.org/wiki/Q380136","display_name":"Enterobacteriaceae Infections","level":5,"score":0.4967513680458069},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4425649642944336},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30928751826286316},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.2592366337776184},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.15340876579284668},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.08344113826751709},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.69667/rmj.25306","doi":"https://doi.org/10.69667/rmj.25306","is_oa":true,"landing_page_url":"https://doi.org/10.69667/rmj.25306","pdf_url":"https://razi.edu.ly/rmj/index.php/hm/article/download/26/22","source":{"id":"https://openalex.org/S5407054572","display_name":"Razi Medical Journal","issn_l":"3080-3624","issn":["3080-3624"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Razi Medical Journal","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.69667/rmj.25306","doi":"https://doi.org/10.69667/rmj.25306","is_oa":true,"landing_page_url":"https://doi.org/10.69667/rmj.25306","pdf_url":"https://razi.edu.ly/rmj/index.php/hm/article/download/26/22","source":{"id":"https://openalex.org/S5407054572","display_name":"Razi Medical Journal","issn_l":"3080-3624","issn":["3080-3624"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Razi Medical Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"sustainable_development_goals_aurora":[],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4412527593.pdf","grobid_xml":"https://content.openalex.org/works/W4412527593.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2891457461","https://openalex.org/W2259505867","https://openalex.org/W2577264591","https://openalex.org/W2153582783","https://openalex.org/W2114596262","https://openalex.org/W2891315930","https://openalex.org/W2104345585","https://openalex.org/W2929636164","https://openalex.org/W2922314136","https://openalex.org/W2808607039"],"abstract_inverted_index":{"Globally,":[0],"intensive":[1,100,103,113,118],"care":[2,101,104,109,114,119],"units":[3,98],"(ICUs)":[4],"are":[5,19],"encountering":[6],"the":[7,29,50,59,67,132,165,231,290,301,306,317],"emergence":[8],"and":[9,14,33,46,61,107,145,152,173,225,312],"spread":[10,318],"of":[11,36,53,64,70,99,160,164,171,240,289,292,319],"antibiotic-resistant":[12],"pathogens,":[13,17],"for":[15,137,234,308],"some":[16],"there":[18],"few":[20],"therapeutic":[21],"options":[22],"available.":[23],"This":[24,304],"study":[25,75,79,286,302],"tries":[26],"to":[27,57,78,149,298,315],"assess":[28,58],"prevalence,":[30],"susceptibility":[31],"pattern,":[32],"risk":[34],"factors":[35],"Carbapenem-Resistant":[37],"Enterobacteriaceae":[38,124,172,246],"(CRE)":[39],"infections":[40,294],"among":[41,295],"ICU":[42],"patients,":[43],"healthcare":[44],"workers,":[45],"surface":[47],"swabs":[48],"in":[49,66,300,321],"medical":[51,68],"center":[52,69],"Tobruk,":[54],"Libya.":[55],"Also,":[56],"incidence":[60],"prevalence":[62],"rate":[63],"CRE":[65,293,320],"Tobruk.":[71],"A":[72,158],"descriptive":[73],"cross-sectional":[74],"was":[76,154],"used":[77],"119":[80,85,166],"collected":[81,88,95],"samples.":[82],"Of":[83],"which,":[84],"samples":[86,93,167,233,239],"were":[87,94,102,125,135],"from":[89,96,177],"patients.":[90],"The":[91,122,147,285],"above":[92],"four":[97],"unit":[105,110,115,120],"(ICU)":[106],"cardiac":[108],"(CCU),":[111],"Pediatric":[112],"(PICU),":[116],"Neonatal":[117],"(NICU).":[121],"identified":[123],"first":[126],"confirmed":[127,133],"by":[128],"biochemical":[129],"methods,":[130],"while":[131],"isolates":[134,170],"tested":[136],"carbapenemase":[138],"production":[139],"using":[140],"three":[141],"discs":[142],"(EME,":[143],"IMP,":[144],"ETP).":[146],"resistance":[148,236],"(Ertapenem,":[150],"Imipenem,":[151],"Meropenem)":[153],"considered":[155],"as":[156,179,243,247],"CRE.":[157],"total":[159],"79":[161,241],"(66.4%)":[162],"out":[163],"yielded":[168],"clinical":[169],"gram":[174],"negative":[175],"bacteria":[176],"patients":[178,296],"follows:":[180,248],"23":[181],"(29.1%)":[182],"Klebsiella":[183,251],"pneumoniae,":[184],"15":[185],"(19%)":[186],"Acinetobacter":[187,255],"baumannii,":[188,256],"12":[189],"(15.2%)":[190],"Escherichia":[191,259],"coli,":[192,260],"7":[193],"(9%)":[194],"Pantoea":[195,271],"sp.,":[196,272],"5":[197,201],"(6.3%)":[198,202],"Pseudomonas":[199,267],"aeruginosa,":[200,268],"Citrobacter":[203,211,263],"freundii,":[204,212,264],"4":[205,261],"(5.1%)":[206,262],"Enterobacter":[207,275],"cloacae,":[208,276],"2":[209,217,221,273,277],"(2.6%)":[210],"3":[213,265,269],"(3.8%)":[214,266,270],"Chryseomonas":[215,279],"luteola,":[216,280],"(2.5%)":[218,222,274,278],"Proteus":[219],"vulgaris,":[220],"Flavimonas":[223],"oriyzihabitans,":[224],"1":[226,281],"(1.3%)":[227,282],"Serratia":[228,283],"marcecens.":[229,284],"Screening":[230],"Enterobacteriaceae-positive":[232],"carbapenem":[235,244],"showed":[237],"48":[238],"(60.8%)":[242],"resistant":[245],"18":[249],"(22.8%)":[250],"pneumonia,":[252],"9":[253],"(11.4%)":[254],"6":[257],"(7.6%)":[258],"provided":[287],"evidence":[288],"presence":[291],"admitted":[297],"ICUs":[299],"centers.":[303],"underscores":[305],"need":[307],"effective":[309],"infection":[310],"prevention":[311],"control":[313],"measures":[314],"avoid":[316],"a":[322],"hospital":[323],"setting.":[324]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2025-10-10T00:00:00"}