{"id":"https://openalex.org/W4412392824","doi":"https://doi.org/10.58347/tml.2025.1733b","title":"Upadacitinib (Rinvoq) for Giant Cell Arteritis","display_name":"Upadacitinib (Rinvoq) for Giant Cell Arteritis","publication_year":2025,"publication_date":"2025-07-21","ids":{"openalex":"https://openalex.org/W4412392824","doi":"https://doi.org/10.58347/tml.2025.1733b","pmid":"https://pubmed.ncbi.nlm.nih.gov/40651014"},"language":"en","primary_location":{"id":"doi:10.58347/tml.2025.1733b","doi":"https://doi.org/10.58347/tml.2025.1733b","is_oa":false,"landing_page_url":"https://doi.org/10.58347/tml.2025.1733b","pdf_url":null,"source":{"id":"https://openalex.org/S977536218","display_name":"\u0098The \u009cmedical letter on drugs and therapeutics/\u0098The \u009cmedical letter","issn_l":"0025-2859","issn":["0025-2859","0025-732X","1523-2859"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["jufo-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310321063","host_organization_name":"The Medical Letter, Inc.","host_organization_lineage":["https://openalex.org/P4310321063"],"host_organization_lineage_names":["The Medical Letter, Inc."],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Medical Letter on Drugs and Therapeutics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6075,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.68466034,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"67","issue":"1733","first_page":"114","last_page":"115"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11616","display_name":"Autoimmune and Inflammatory Disorders Research","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/upadacitinib","display_name":"upadacitinib","score":1.0},{"id":"https://openalex.org/keywords/giant-cell-arteritis","display_name":"giant cell arteritis","score":0.8579999804496765},{"id":"https://openalex.org/keywords/jak-inhibitors","display_name":"JAK inhibitors","score":0.7450000047683716},{"id":"https://openalex.org/keywords/oral-therapy","display_name":"oral therapy","score":0.6579999923706055},{"id":"https://openalex.org/keywords/drug-approval","display_name":"drug approval","score":0.8090000152587891},{"id":"https://openalex.org/keywords/rheumatoid-arthritis","display_name":"rheumatoid arthritis","score":0.921999990940094},{"id":"https://openalex.org/keywords/psoriatic-arthritis","display_name":"psoriatic arthritis","score":0.9120000004768372},{"id":"https://openalex.org/keywords/ankylosing-spondylitis","display_name":"ankylosing spondylitis","score":0.9570000171661377},{"id":"https://openalex.org/keywords/atopic-dermatitis","display_name":"atopic dermatitis","score":0.8479999899864197},{"id":"https://openalex.org/keywords/ulcerative-colitis","display_name":"ulcerative colitis","score":0.9169999957084656},{"id":"https://openalex.org/keywords/crohn-s-disease","display_name":"Crohn's disease","score":0.9980000257492065}],"concepts":[{"id":"https://openalex.org/C2776712624","wikidata":"https://www.wikidata.org/wiki/Q707816","display_name":"Giant cell arteritis","level":4,"score":0.7533658742904663},{"id":"https://openalex.org/C2781343717","wikidata":"https://www.wikidata.org/wiki/Q1751810","display_name":"Arteritis","level":2,"score":0.47176769375801086},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3310055136680603},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.16726037859916687},{"id":"https://openalex.org/C2776015282","wikidata":"https://www.wikidata.org/wiki/Q644318","display_name":"Vasculitis","level":3,"score":0.12480524182319641},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.58347/tml.2025.1733b","doi":"https://doi.org/10.58347/tml.2025.1733b","is_oa":false,"landing_page_url":"https://doi.org/10.58347/tml.2025.1733b","pdf_url":null,"source":{"id":"https://openalex.org/S977536218","display_name":"\u0098The \u009cmedical letter on drugs and therapeutics/\u0098The \u009cmedical letter","issn_l":"0025-2859","issn":["0025-2859","0025-732X","1523-2859"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["jufo-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310321063","host_organization_name":"The Medical Letter, Inc.","host_organization_lineage":["https://openalex.org/P4310321063"],"host_organization_lineage_names":["The Medical Letter, Inc."],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Medical Letter on Drugs and Therapeutics","raw_type":"journal-article"},{"id":"pmid:40651014","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40651014","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Medical letter on drugs and therapeutics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2088451200","https://openalex.org/W2042636846","https://openalex.org/W2009103220","https://openalex.org/W2784609481","https://openalex.org/W4290128960","https://openalex.org/W2443870276","https://openalex.org/W2417507891","https://openalex.org/W2321565791","https://openalex.org/W2012072279","https://openalex.org/W2924526404"],"abstract_inverted_index":{"The":[0],"oral":[1],"Janus":[2],"kinase":[3],"(JAK)":[4],"inhibitor":[5],"upadacitinib":[6],"(Rinvoq":[7],"\u2013":[8],"Abbvie)":[9],"has":[10],"been":[11],"approved":[12,24],"by":[13],"the":[14],"FDA":[15],"for":[16,26],"treatment":[17,27],"of":[18,28],"giant":[19],"cell":[20],"arteritis.":[21],"Upadacitinib":[22],"was":[23],"earlier":[25],"rheumatoid":[29],"arthritis,":[30,32],"psoriatic":[31],"ankylosing":[33],"spondylitis,":[34],"nonradiographic":[35],"axial":[36],"spondyloarthritis,":[37],"atopic":[38],"dermatitis,":[39],"ulcerative":[40],"colitis,":[41],"and":[42],"Crohn's":[43],"disease.":[44]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2025-10-10T00:00:00"}