{"id":"https://openalex.org/W4412181513","doi":"https://doi.org/10.2210/pdb7kni/pdb","title":"Cryo-EM structure of Triple ACE2-bound SARS-CoV-2 Trimer Spike at pH 5.5","display_name":"Cryo-EM structure of Triple ACE2-bound SARS-CoV-2 Trimer Spike at pH 5.5","publication_year":2020,"publication_date":"2020-11-04","ids":{"openalex":"https://openalex.org/W4412181513","doi":"https://doi.org/10.2210/pdb7kni/pdb"},"language":"en","primary_location":{"id":"doi:10.2210/pdb7kni/pdb","doi":"https://doi.org/10.2210/pdb7kni/pdb","is_oa":false,"landing_page_url":"https://doi.org/10.2210/pdb7kni/pdb","pdf_url":null,"source":{"id":"https://openalex.org/S7407063902","display_name":"Worldwide Protein Data Bank","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Worldwide Protein Data Bank","raw_type":"dataset"},"volume":null,"type":"dataset","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018275034","display_name":"Jason Gorman","orcid":"https://orcid.org/0000-0002-3775-6560","observed_orcids":["https://orcid.org/0000-0002-3775-6560"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. Gorman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025760365","display_name":"Micah Rapp","orcid":"https://orcid.org/0000-0002-3088-1385","observed_orcids":["https://orcid.org/0000-0002-3088-1385"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Rapp","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043677118","display_name":"Peter D. Kwong","orcid":"https://orcid.org/0000-0003-3560-232X","observed_orcids":["https://orcid.org/0000-0003-3560-232X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P.D. Kwong","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5060205129","display_name":"Lawrence S. Shapiro","orcid":"https://orcid.org/0000-0001-9943-8819","observed_orcids":["https://orcid.org/0000-0001-9943-8819","https://orcid.org/0000-0001-5630-7181"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L. Shapiro","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10857","display_name":"Advanced Electron Microscopy Techniques and Applications","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sars-cov-2","display_name":"SARS-CoV-2","score":0.9200000166893005},{"id":"https://openalex.org/keywords/spike-trimer","display_name":"spike trimer","score":0.8019999861717224},{"id":"https://openalex.org/keywords/ace2-receptor","display_name":"ACE2 receptor","score":0.8579999804496765},{"id":"https://openalex.org/keywords/receptor-binding-domain","display_name":"receptor binding domain","score":0.6209999918937683},{"id":"https://openalex.org/keywords/low-ph","display_name":"low pH","score":0.7789999842643738},{"id":"https://openalex.org/keywords/spike-protein","display_name":"spike protein","score":0.5080000162124634},{"id":"https://openalex.org/keywords/virus-entry","display_name":"viral entry","score":0.34599998593330383}],"concepts":[{"id":"https://openalex.org/C2776403692","wikidata":"https://www.wikidata.org/wiki/Q898416","display_name":"Trimer","level":3,"score":0.8831160068511963},{"id":"https://openalex.org/C2781390188","wikidata":"https://www.wikidata.org/wiki/Q25203449","display_name":"Spike (software development)","level":2,"score":0.7653768062591553},{"id":"https://openalex.org/C2909509916","wikidata":"https://www.wikidata.org/wiki/Q22329850","display_name":"Spike Protein","level":5,"score":0.6273146271705627},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5450981855392456},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5330867767333984},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.5090979933738708},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.45653092861175537},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.35945266485214233},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.24508661031723022},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.18083643913269043},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.10582658648490906},{"id":"https://openalex.org/C2779546866","wikidata":"https://www.wikidata.org/wiki/Q531306","display_name":"Dimer","level":2,"score":0.09121844172477722},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.05710437893867493},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.0},{"id":"https://openalex.org/C115903868","wikidata":"https://www.wikidata.org/wiki/Q80993","display_name":"Software engineering","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.2210/pdb7kni/pdb","doi":"https://doi.org/10.2210/pdb7kni/pdb","is_oa":false,"landing_page_url":"https://doi.org/10.2210/pdb7kni/pdb","pdf_url":null,"source":{"id":"https://openalex.org/S7407063902","display_name":"Worldwide Protein Data Bank","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Worldwide Protein Data Bank","raw_type":"dataset"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4412138888","https://openalex.org/W4412163610","https://openalex.org/W4413573283"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}