{"id":"https://openalex.org/W4411998942","doi":"https://doi.org/10.1016/s0016-5085(25)04199-x","title":"Tu1520: ACCURATE EARLY HEPATOCELLULAR CARCINOMA (HCC) DETECTION WITH PLASMA DNA METHYLATION BIOMARKERS DERIVED FROM A WHOLE BODY ATLAS","display_name":"Tu1520: ACCURATE EARLY HEPATOCELLULAR CARCINOMA (HCC) DETECTION WITH PLASMA DNA METHYLATION BIOMARKERS DERIVED FROM A WHOLE BODY ATLAS","publication_year":2025,"publication_date":"2025-05-01","ids":{"openalex":"https://openalex.org/W4411998942","doi":"https://doi.org/10.1016/s0016-5085(25)04199-x"},"language":"en","primary_location":{"id":"doi:10.1016/s0016-5085(25)04199-x","doi":"https://doi.org/10.1016/s0016-5085(25)04199-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0016-5085(25)04199-x","pdf_url":null,"source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Aneesha Tewari","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aneesha Tewari","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102944998","display_name":"Sarah S. Yang","orcid":"https://orcid.org/0000-0003-3811-6378","observed_orcids":["https://orcid.org/0000-0003-3811-6378"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sarah Yang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Alvin Lau","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alvin Lau","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030446110","display_name":"Yao\u2010Chun Hsu","orcid":"https://orcid.org/0000-0001-8984-5103","observed_orcids":["https://orcid.org/0000-0001-8984-5103"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yao-Chun Hsu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071989098","display_name":"Ming\u2010Lung Yu","orcid":"https://orcid.org/0000-0001-8145-1900","observed_orcids":["https://orcid.org/0000-0001-8145-1900"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ming-Lung Yu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020095413","display_name":"Cheng\u2010Hao Tseng","orcid":"https://orcid.org/0000-0003-4507-2414","observed_orcids":["https://orcid.org/0000-0003-4507-2414"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Cheng-Hao Tseng","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057578521","display_name":"Ming\u2010Lun Yeh","orcid":"https://orcid.org/0000-0003-3728-7618","observed_orcids":["https://orcid.org/0000-0003-3728-7618"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ming-Lun Yeh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Po Yao Hsu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Po Yao Hsu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Ritish Patnaik","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ritish Patnaik","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037490912","display_name":"Peter Yigitcan Washington","orcid":"https://orcid.org/0000-0003-3276-4411","observed_orcids":["https://orcid.org/0000-0003-3276-4411"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Peter Washington","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059854140","display_name":"Chuba Oyolu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chuba Oyolu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035138091","display_name":"Shan Xiang Wang","orcid":"https://orcid.org/0000-0001-8420-9554","observed_orcids":["https://orcid.org/0000-0001-8420-9554"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shan X. Wang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091013365","display_name":"Nathan M. Hunkapiller","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nathan Hunkapiller","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5038740509","display_name":"Mindie H. Nguyen","orcid":"https://orcid.org/0000-0002-6275-4989","observed_orcids":["https://orcid.org/0000-0002-6275-4989","https://orcid.org/0000-0002-5538-0237"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mindie H. Nguyen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4180,"currency":"USD","value_usd":4180},"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"169","issue":"1","first_page":"S","last_page":"1439"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.3970000147819519,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.3970000147819519,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.295199990272522,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.21660000085830688,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hepatocellular-carcinoma","display_name":"hepatocellular carcinoma","score":0.9890000224113464},{"id":"https://openalex.org/keywords/early-cancer-detection","display_name":"early cancer detection","score":0.9639999866485596},{"id":"https://openalex.org/keywords/plasma-dna-methylation","display_name":"plasma DNA methylation","score":0.9739999771118164},{"id":"https://openalex.org/keywords/methylation-markers","display_name":"methylation biomarkers","score":0.8939999938011169},{"id":"https://openalex.org/keywords/liquid-biopsy","display_name":"liquid biopsy","score":0.7139999866485596}],"concepts":[{"id":"https://openalex.org/C2778019345","wikidata":"https://www.wikidata.org/wiki/Q1148337","display_name":"Hepatocellular carcinoma","level":2,"score":0.8570501208305359},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.7259955406188965},{"id":"https://openalex.org/C2776673561","wikidata":"https://www.wikidata.org/wiki/Q655357","display_name":"Atlas (anatomy)","level":2,"score":0.6971872448921204},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.43806272745132446},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4263456165790558},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4073997139930725},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.35181939601898193},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.34123149514198303},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3289644718170166},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.10765936970710754},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.08704543113708496},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.06980997323989868},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.05051127076148987}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s0016-5085(25)04199-x","doi":"https://doi.org/10.1016/s0016-5085(25)04199-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0016-5085(25)04199-x","pdf_url":null,"source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4411998744","https://openalex.org/W2031842191","https://openalex.org/W7218152534","https://openalex.org/W4246147147","https://openalex.org/W6967672557","https://openalex.org/W2889162157","https://openalex.org/W4320709211","https://openalex.org/W4415664212","https://openalex.org/W2323521477","https://openalex.org/W4382358409"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-17T09:40:24.721904","created_date":"2025-10-10T00:00:00"}