{"id":"https://openalex.org/W4411908121","doi":"https://doi.org/10.1158/1078-0432.29444365","title":"Supplementary Figure S3 from Quantitative Protein Expression of Antibody\u2013Drug Conjugate Targets in EGFR Mutated and Wild-type Non\u2013Small Cell Lung Cancer","display_name":"Supplementary Figure S3 from Quantitative Protein Expression of Antibody\u2013Drug Conjugate Targets in EGFR Mutated and Wild-type Non\u2013Small Cell Lung Cancer","publication_year":2025,"publication_date":"2025-07-01","ids":{"openalex":"https://openalex.org/W4411908121","doi":"https://doi.org/10.1158/1078-0432.29444365"},"language":"en","primary_location":{"id":"doi:10.1158/1078-0432.29444365","doi":"https://doi.org/10.1158/1078-0432.29444365","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.29444365","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/1078-0432.29444365","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008473824","display_name":"Ioannis Panagiotis Trontzas","orcid":"https://orcid.org/0000-0003-3706-9995","observed_orcids":["https://orcid.org/0000-0003-3706-9995"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ioannis P. Trontzas","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3706-9995","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104186042","display_name":"Mengni He","orcid":"https://orcid.org/0000-0003-4228-4462","observed_orcids":["https://orcid.org/0000-0003-4228-4462","https://orcid.org/0000-0003-4456-680X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mengni He","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4228-4462","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049906346","display_name":"Anna Wurtz","orcid":"https://orcid.org/0000-0002-9720-8427","observed_orcids":["https://orcid.org/0000-0002-9720-8427"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anna Wurtz","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9720-8427","affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Charles J. Robbins","orcid":"https://orcid.org/0000-0002-3130-7107","observed_orcids":["https://orcid.org/0000-0002-3130-7107"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Charles J. Robbins","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3130-7107","affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Nathaniel Robinson","orcid":"https://orcid.org/0000-0003-1238-0381","observed_orcids":["https://orcid.org/0000-0003-1238-0381"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nathaniel Robinson","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1238-0381","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086534064","display_name":"Katherine Bates","orcid":"https://orcid.org/0000-0001-8956-6331","observed_orcids":["https://orcid.org/0000-0001-8956-6331"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Katherine Bates","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8956-6331","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101791604","display_name":"Matthew Liu","orcid":"https://orcid.org/0000-0002-2229-5124","observed_orcids":["https://orcid.org/0000-0002-2229-5124"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Matthew Liu","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2229-5124","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011946828","display_name":"Thazin Nwe Aung","orcid":"https://orcid.org/0000-0003-4150-0426","observed_orcids":["https://orcid.org/0000-0003-4150-0426"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Thazin N. Aung","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4150-0426","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004278549","display_name":"Liam Scott","orcid":"https://orcid.org/0000-0002-6114-6324","observed_orcids":["https://orcid.org/0000-0002-6114-6324"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Liam Scott","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-6114-6324","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046787323","display_name":"Nay Nwe Nyein Chan","orcid":"https://orcid.org/0009-0006-1633-6125","observed_orcids":["https://orcid.org/0009-0006-1633-6125"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nay Chan","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0006-1633-6125","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009801511","display_name":"Sneha Burela","orcid":"https://orcid.org/0000-0003-0287-0336","observed_orcids":["https://orcid.org/0000-0003-0287-0336"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sneha Burela","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0287-0336","affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Jacob Schillo","orcid":"https://orcid.org/0000-0002-4897-3165","observed_orcids":["https://orcid.org/0000-0002-4897-3165"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jacob Schillo","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-4897-3165","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071022580","display_name":"Daniel C. Liebler","orcid":"https://orcid.org/0000-0002-7873-3031","observed_orcids":["https://orcid.org/0000-0002-7873-3031"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel C. Liebler","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-7873-3031","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043898530","display_name":"Salisha Hill","orcid":"https://orcid.org/0000-0002-4145-969X","observed_orcids":["https://orcid.org/0000-0002-4145-969X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Salisha Hill","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-4145-969X","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037110629","display_name":"Ryan D. Morrison","orcid":"https://orcid.org/0000-0003-4995-8001","observed_orcids":["https://orcid.org/0000-0003-4995-8001"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ryan D. Morrison","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4995-8001","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029208140","display_name":"Ioannis Athanasios Vathiotis","orcid":"https://orcid.org/0000-0002-1772-5986","observed_orcids":["https://orcid.org/0000-0002-1772-5986"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ioannis Vathiotis","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1772-5986","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049509860","display_name":"Konstantinos N. Syrigos","orcid":"https://orcid.org/0000-0002-3474-1363","observed_orcids":["https://orcid.org/0000-0002-3474-1363"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Konstantinos N. Syrigos","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3474-1363","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028192791","display_name":"Sarah B. Goldberg","orcid":"https://orcid.org/0000-0002-0920-1381","observed_orcids":["https://orcid.org/0000-0002-0920-1381"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sarah B. Goldberg","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-0920-1381","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067248479","display_name":"Katerina A. Politi","orcid":"https://orcid.org/0000-0001-6064-4527","observed_orcids":["https://orcid.org/0000-0001-6064-4527","https://orcid.org/0000-0002-6399-2735"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Katerina Politi","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6064-4527","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5027326018","display_name":"David L. Rimm","orcid":"https://orcid.org/0000-0001-5820-4397","observed_orcids":["https://orcid.org/0000-0001-5820-4397"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David L. Rimm","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5820-4397","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10417","display_name":"Lung Cancer Treatments and Mutations","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10417","display_name":"Lung Cancer Treatments and Mutations","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10755","display_name":"HER2/EGFR in Cancer Research","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12334","display_name":"Lung Cancer Research Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antibody-drug-conjugates","display_name":"antibody-drug conjugates","score":0.8859999775886536},{"id":"https://openalex.org/keywords/egfr","display_name":"EGFR","score":0.515999972820282},{"id":"https://openalex.org/keywords/non-small-cell-lung-cancer","display_name":"non-small cell lung cancer","score":0.8989999890327454},{"id":"https://openalex.org/keywords/her2","display_name":"HER2","score":0.921999990940094},{"id":"https://openalex.org/keywords/trop2","display_name":"TROP2","score":0.9990000128746033},{"id":"https://openalex.org/keywords/her3","display_name":"HER3","score":0.9990000128746033},{"id":"https://openalex.org/keywords/protein-expression","display_name":"protein expression","score":0.7210000157356262},{"id":"https://openalex.org/keywords/egfr-mutation","display_name":"EGFR mutation","score":0.7459999918937683}],"concepts":[{"id":"https://openalex.org/C197336794","wikidata":"https://www.wikidata.org/wiki/Q5161150","display_name":"Conjugate","level":2,"score":0.7558720111846924},{"id":"https://openalex.org/C2777325958","wikidata":"https://www.wikidata.org/wiki/Q1069596","display_name":"Antibody-drug conjugate","level":4,"score":0.7114686965942383},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5999928712844849},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.5580748915672302},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.5428888201713562},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.5339654088020325},{"id":"https://openalex.org/C6856738","wikidata":"https://www.wikidata.org/wiki/Q331672","display_name":"Protein expression","level":3,"score":0.5062236189842224},{"id":"https://openalex.org/C207583985","wikidata":"https://www.wikidata.org/wiki/Q128723","display_name":"Wild type","level":4,"score":0.4621674716472626},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.41803067922592163},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3984715938568115},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.37879183888435364},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3351166546344757},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.30083104968070984},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.2552335858345032},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.22583231329917908},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.21008703112602234},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.19432929158210754},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.1890919804573059},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.17599302530288696},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10192945599555969},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.05588880181312561},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/1078-0432.29444365","doi":"https://doi.org/10.1158/1078-0432.29444365","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.29444365","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1158/1078-0432.29444365","doi":"https://doi.org/10.1158/1078-0432.29444365","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.29444365","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4408191659","https://openalex.org/W4411908097","https://openalex.org/W4400236299","https://openalex.org/W1033399831","https://openalex.org/W574040538","https://openalex.org/W1996910715","https://openalex.org/W4412484841","https://openalex.org/W4410805137","https://openalex.org/W1195700501","https://openalex.org/W2146346695"],"abstract_inverted_index":{"Linear":[0],"correlation":[1],"between":[2],"HER2,":[3],"TROP2,":[4],"HER3,":[5],"and":[6,10],"EGFR":[7],"quantitative":[8],"expression":[9],"cases":[11],"above":[12],"lower":[13],"assay":[14],"limits":[15],"in":[16],"the":[17],"EGFRmut":[18],"non-small":[19],"cell":[20],"lung":[21],"cancer":[22],"cohort.":[23]},"counts_by_year":[],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2025-10-10T00:00:00"}