{"id":"https://openalex.org/W4411849219","doi":"https://doi.org/10.1007/s11239-025-03141-y","title":"Efficacy and safety of apixaban versus vitamin K antagonists in patients with heartmate 3 fully magnetically levitated left ventricular assist device: a comprehensive meta-analysis","display_name":"Efficacy and safety of apixaban versus vitamin K antagonists in patients with heartmate 3 fully magnetically levitated left ventricular assist device: a comprehensive meta-analysis","publication_year":2025,"publication_date":"2025-07-01","ids":{"openalex":"https://openalex.org/W4411849219","doi":"https://doi.org/10.1007/s11239-025-03141-y","pmid":"https://pubmed.ncbi.nlm.nih.gov/40593455"},"language":"en","primary_location":{"id":"doi:10.1007/s11239-025-03141-y","doi":"https://doi.org/10.1007/s11239-025-03141-y","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11239-025-03141-y","pdf_url":null,"source":{"id":"https://openalex.org/S108510729","display_name":"Journal of Thrombosis and Thrombolysis","issn_l":"0929-5305","issn":["0929-5305","1573-742X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Thrombosis and Thrombolysis","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Andrea Tripoli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154387261","display_name":"Vita-Salute San Raffaele University","ror":"https://ror.org/01gmqr298","country_code":"IT","type":"education","lineage":["https://openalex.org/I154387261"]},{"id":"https://openalex.org/I4210133214","display_name":"IRCCS Ospedale San Raffaele","ror":"https://ror.org/039zxt351","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210133214","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Andrea Tripoli","raw_affiliation_strings":["Cardiac Intensive Care Unit, San Raffaele Hospital, Universit\u00e0 Vita-Salute San Raffaele, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiac Intensive Care Unit, San Raffaele Hospital, Universit\u00e0 Vita-Salute San Raffaele, Milan, Italy","institution_ids":["https://openalex.org/I154387261","https://openalex.org/I4210133214"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112172825","display_name":"Miguel A. Samaniego-Laguna","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200362191","display_name":"Universidad Aut\u00f3noma Metropolitana","ror":"https://ror.org/02kta5139","country_code":"MX","type":"education","lineage":["https://openalex.org/I200362191"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Miguel A. Samaniego","raw_affiliation_strings":["Universidad Aut\u00f3noma Metropolitana, Ciudad de M\u00e9xico, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidad Aut\u00f3noma Metropolitana, Ciudad de M\u00e9xico, Mexico","institution_ids":["https://openalex.org/I200362191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069442260","display_name":"Norma Nicole Gamarra Valverde","orcid":"https://orcid.org/0000-0001-9299-8872","observed_orcids":["https://orcid.org/0000-0001-9299-8872"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Norma N. Gamarra-Valverde","raw_affiliation_strings":["Alberto Hurtado Faculty of Human Medicine, Lima, Peru"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alberto Hurtado Faculty of Human Medicine, Lima, Peru","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112613437","display_name":"Sindhu Selvam","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79510175","display_name":"Cardiff University","ror":"https://ror.org/03kk7td41","country_code":"GB","type":"education","lineage":["https://openalex.org/I79510175"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Shivraj Paneer Selvam","raw_affiliation_strings":["Cardiff University, Cardiff, Wales, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiff University, Cardiff, Wales, UK","institution_ids":["https://openalex.org/I79510175"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081929932","display_name":"Edgardo Kaplinsky","orcid":"https://orcid.org/0000-0002-6399-6736","observed_orcids":["https://orcid.org/0000-0002-6399-6736"]},"institutions":[{"id":"https://openalex.org/I4210153095","display_name":"Hospital Municipal de Badalona","ror":"https://ror.org/0495vrm88","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210153095"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Edgardo Kaplinsky","raw_affiliation_strings":["Badalona Municipal Hospital, Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Badalona Municipal Hospital, Barcelona, Spain","institution_ids":["https://openalex.org/I4210153095"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009771382","display_name":"Alejandro Barbagelata","orcid":"https://orcid.org/0000-0001-6803-2605","observed_orcids":["https://orcid.org/0000-0001-6803-2605"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I29406707","display_name":"Pontificia Universidad Cat\u00f3lica Argentina","ror":"https://ror.org/0422kzb24","country_code":"AR","type":"education","lineage":["https://openalex.org/I29406707"]}],"countries":["AR","US"],"is_corresponding":false,"raw_author_name":"Alejandro Barbagelata","raw_affiliation_strings":["Duke University, Durham, North Carolina, USA","Universidad Catolica Argentina, Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke University, Durham, North Carolina, USA","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Universidad Catolica Argentina, Buenos Aires, Argentina","institution_ids":["https://openalex.org/I29406707"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016891339","display_name":"Anna Mara Scandroglio","orcid":"https://orcid.org/0000-0003-0639-8227","observed_orcids":["https://orcid.org/0000-0003-0639-8227"]},"institutions":[{"id":"https://openalex.org/I154387261","display_name":"Vita-Salute San Raffaele University","ror":"https://ror.org/01gmqr298","country_code":"IT","type":"education","lineage":["https://openalex.org/I154387261"]},{"id":"https://openalex.org/I4210133214","display_name":"IRCCS Ospedale San Raffaele","ror":"https://ror.org/039zxt351","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210133214","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Anna Mara Scandroglio","raw_affiliation_strings":["Cardiac Intensive Care Unit, San Raffaele Hospital, Universit\u00e0 Vita-Salute San Raffaele, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiac Intensive Care Unit, San Raffaele Hospital, Universit\u00e0 Vita-Salute San Raffaele, Milan, Italy","institution_ids":["https://openalex.org/I154387261","https://openalex.org/I4210133214"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006211635","display_name":"Juliana Martins Giorgi","orcid":"https://orcid.org/0009-0007-7271-4845","observed_orcids":["https://orcid.org/0009-0007-7271-4845"]},"institutions":[{"id":"https://openalex.org/I2800288331","display_name":"Hospital Israelita Albert Einstein","ror":"https://ror.org/04cwrbc27","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I2800288331"]},{"id":"https://openalex.org/I4210149843","display_name":"Hospital S\u00edrio-Liban\u00eas","ror":"https://ror.org/03r5mk904","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I4210149843"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Juliana Giorgi","raw_affiliation_strings":["Hospital Albert Einstein, S\u00e3o Paulo, Brazil. julianagiorgi@hotmail.com","Hospital S\u00edrio Liban\u00eas, S\u00e3o Paulo, Brazil. julianagiorgi@hotmail.com"],"raw_orcid":"https://orcid.org/0009-0007-7271-4845","affiliations":[{"raw_affiliation_string":"Hospital Albert Einstein, S\u00e3o Paulo, Brazil. julianagiorgi@hotmail.com","institution_ids":["https://openalex.org/I2800288331"]},{"raw_affiliation_string":"Hospital S\u00edrio Liban\u00eas, S\u00e3o Paulo, Brazil. julianagiorgi@hotmail.com","institution_ids":["https://openalex.org/I4210149843"]}]}],"institutions":[],"countries_distinct_count":7,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5006211635"],"corresponding_institution_ids":["https://openalex.org/I2800288331","https://openalex.org/I4210149843"],"apc_list":{"value":3890,"currency":"USD","value_usd":3890},"apc_paid":null,"fwci":4.1411,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.94232526,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"58","issue":"7","first_page":"750","last_page":"760"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10675","display_name":"Mechanical Circulatory Support Devices","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10675","display_name":"Mechanical Circulatory Support Devices","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/apixaban","display_name":"apixaban","score":0.9990000128746033},{"id":"https://openalex.org/keywords/vitamin-k-antagonists","display_name":"vitamin K antagonists","score":0.9750000238418579},{"id":"https://openalex.org/keywords/heartmate-3","display_name":"HeartMate 3","score":0.8379999995231628},{"id":"https://openalex.org/keywords/left-ventricular-assist-device","display_name":"left ventricular assist device","score":0.9850000143051147},{"id":"https://openalex.org/keywords/direct-oral-anticoagulants","display_name":"direct oral anticoagulants","score":0.8849999904632568},{"id":"https://openalex.org/keywords/factor-xa-inhibitors","display_name":"factor Xa inhibitors","score":0.9829999804496765},{"id":"https://openalex.org/keywords/anticoagulation","display_name":"anticoagulation","score":0.8669999837875366},{"id":"https://openalex.org/keywords/major-bleeding","display_name":"major bleeding","score":0.9490000009536743},{"id":"https://openalex.org/keywords/thromboembolic-events","display_name":"thromboembolic events","score":0.8220000267028809},{"id":"https://openalex.org/keywords/stroke-prevention","display_name":"stroke prevention","score":0.7329999804496765},{"id":"https://openalex.org/keywords/all-cause-mortality","display_name":"all-cause mortality","score":0.7950000166893005},{"id":"https://openalex.org/keywords/warfarin","display_name":"warfarin","score":0.8119999766349792},{"id":"https://openalex.org/keywords/mechanical-circulatory-support","display_name":"mechanical circulatory support","score":0.8429999947547913},{"id":"https://openalex.org/keywords/gastrointestinal-bleeding","display_name":"gastrointestinal bleeding","score":0.6100000143051147},{"id":"https://openalex.org/keywords/anticoagulation-adherence","display_name":"anticoagulation adherence","score":0.8489999771118164}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9245965480804443},{"id":"https://openalex.org/C2780638905","wikidata":"https://www.wikidata.org/wiki/Q414462","display_name":"Apixaban","level":5,"score":0.7553540468215942},{"id":"https://openalex.org/C2778774980","wikidata":"https://www.wikidata.org/wiki/Q2897721","display_name":"Ventricular assist device","level":3,"score":0.6176691651344299},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.6076099872589111},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5763314962387085},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5291025042533875},{"id":"https://openalex.org/C194409129","wikidata":"https://www.wikidata.org/wiki/Q103824","display_name":"Hematology","level":2,"score":0.4693238437175751},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.4020284414291382},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.14410024881362915},{"id":"https://openalex.org/C2776301958","wikidata":"https://www.wikidata.org/wiki/Q407431","display_name":"Warfarin","level":3,"score":0.13214540481567383},{"id":"https://openalex.org/C2778661090","wikidata":"https://www.wikidata.org/wiki/Q420262","display_name":"Rivaroxaban","level":4,"score":0.0871354341506958}],"mesh":[{"descriptor_ui":"D000925","descriptor_name":"Anticoagulants","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D000925","descriptor_name":"Anticoagulants","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D006353","descriptor_name":"Heart-Assist Devices","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D006470","descriptor_name":"Hemorrhage","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011720","descriptor_name":"Pyrazoles","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D011720","descriptor_name":"Pyrazoles","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D011728","descriptor_name":"Pyridones","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D011728","descriptor_name":"Pyridones","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D013923","descriptor_name":"Thromboembolism","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D014812","descriptor_name":"Vitamin K","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D065427","descriptor_name":"Factor Xa Inhibitors","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D065427","descriptor_name":"Factor Xa Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/s11239-025-03141-y","doi":"https://doi.org/10.1007/s11239-025-03141-y","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11239-025-03141-y","pdf_url":null,"source":{"id":"https://openalex.org/S108510729","display_name":"Journal of Thrombosis and Thrombolysis","issn_l":"0929-5305","issn":["0929-5305","1573-742X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Thrombosis and Thrombolysis","raw_type":"journal-article"},{"id":"pmid:40593455","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40593455","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of thrombosis and thrombolysis","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"},{"display_name":"Meta-Analysis","id":"https://openalex.org/study-designs/meta-analysis"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W2016875529","https://openalex.org/W2072726752","https://openalex.org/W2096246254","https://openalex.org/W2097854437","https://openalex.org/W2118092611","https://openalex.org/W2136489990","https://openalex.org/W2162508946","https://openalex.org/W2165719156","https://openalex.org/W2186240085","https://openalex.org/W2612305512","https://openalex.org/W2613429775","https://openalex.org/W2789655849","https://openalex.org/W2796496697","https://openalex.org/W2810340659","https://openalex.org/W2922229775","https://openalex.org/W3019483664","https://openalex.org/W3173282411","https://openalex.org/W3186595813","https://openalex.org/W3199088730","https://openalex.org/W3201403242","https://openalex.org/W4205709732","https://openalex.org/W4206066642","https://openalex.org/W4294958467","https://openalex.org/W4362583533","https://openalex.org/W4365136260","https://openalex.org/W4372311437","https://openalex.org/W4380785311","https://openalex.org/W4388590204","https://openalex.org/W4389209917","https://openalex.org/W4393995537","https://openalex.org/W4394684611","https://openalex.org/W4396708723","https://openalex.org/W4403586458"],"related_works":["https://openalex.org/W4409842671","https://openalex.org/W7118528849","https://openalex.org/W4206066642","https://openalex.org/W4414167440","https://openalex.org/W7123362500","https://openalex.org/W4405212307","https://openalex.org/W4406873576","https://openalex.org/W7154985707","https://openalex.org/W7154627470","https://openalex.org/W4396708723"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":3}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2025-10-10T00:00:00"}