{"id":"https://openalex.org/W4411555993","doi":"https://doi.org/10.1016/j.molcel.2025.05.035","title":"BAG2 releases SAMD4B upon sensing of arginine deficiency to promote tumor cell survival","display_name":"BAG2 releases SAMD4B upon sensing of arginine deficiency to promote tumor cell survival","publication_year":2025,"publication_date":"2025-06-23","ids":{"openalex":"https://openalex.org/W4411555993","doi":"https://doi.org/10.1016/j.molcel.2025.05.035","pmid":"https://pubmed.ncbi.nlm.nih.gov/40555234"},"language":"en","primary_location":{"id":"doi:10.1016/j.molcel.2025.05.035","doi":"https://doi.org/10.1016/j.molcel.2025.05.035","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.molcel.2025.05.035","pdf_url":null,"source":{"id":"https://openalex.org/S156208185","display_name":"Molecular Cell","issn_l":"1097-2765","issn":["1097-2765","1097-4164"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Cell","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010790887","display_name":"Mengying Chen","orcid":"https://orcid.org/0000-0001-6856-2921","observed_orcids":["https://orcid.org/0000-0001-6856-2921"]},"institutions":[{"id":"https://openalex.org/I133868755","display_name":"Shanghai Medical College of Fudan University","ror":"https://ror.org/01zntxs11","country_code":"CN","type":"education","lineage":["https://openalex.org/I133868755","https://openalex.org/I24943067"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210093194","display_name":"Fudan University Shanghai Cancer Center","ror":"https://ror.org/00my25942","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093194"]},{"id":"https://openalex.org/I4391768195","display_name":"State Key Laboratory of Medical Neurobiology","ror":"https://ror.org/00nn53y54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I24943067","https://openalex.org/I4391768195"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Meng-Ying Chen","raw_affiliation_strings":["Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences and School of Basic Medical Sciences; Cancer Institutes, Key Laboratory of Breast Cancer in Shanghai; Shanghai Key Laboratory of Radiation Oncology; The Shanghai Key Laboratory of Medical Epigenetics, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences and School of Basic Medical Sciences; Cancer Institutes, Key Laboratory of Breast Cancer in Shanghai; Shanghai Key Laboratory of Radiation Oncology; The Shanghai Key Laboratory of Medical Epigenetics, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I133868755","https://openalex.org/I24943067","https://openalex.org/I4210093194","https://openalex.org/I4391768195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109578563","display_name":"Chunyu Sun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I133868755","display_name":"Shanghai Medical College of Fudan University","ror":"https://ror.org/01zntxs11","country_code":"CN","type":"education","lineage":["https://openalex.org/I133868755","https://openalex.org/I24943067"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210093194","display_name":"Fudan University Shanghai Cancer Center","ror":"https://ror.org/00my25942","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093194"]},{"id":"https://openalex.org/I4391768195","display_name":"State Key Laboratory of Medical Neurobiology","ror":"https://ror.org/00nn53y54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I24943067","https://openalex.org/I4391768195"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chun-Yu Sun","raw_affiliation_strings":["Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences and School of Basic Medical Sciences; Cancer Institutes, Key Laboratory of Breast Cancer in Shanghai; Shanghai Key Laboratory of Radiation Oncology; The Shanghai Key Laboratory of Medical Epigenetics, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences and School of Basic Medical Sciences; Cancer Institutes, Key Laboratory of Breast Cancer in Shanghai; Shanghai Key Laboratory of Radiation Oncology; The Shanghai Key Laboratory of Medical Epigenetics, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I133868755","https://openalex.org/I24943067","https://openalex.org/I4210093194","https://openalex.org/I4391768195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018564552","display_name":"Ru Zhao","orcid":"https://orcid.org/0000-0001-8475-6398","observed_orcids":["https://orcid.org/0000-0001-8475-6398"]},"institutions":[{"id":"https://openalex.org/I133868755","display_name":"Shanghai Medical College of Fudan University","ror":"https://ror.org/01zntxs11","country_code":"CN","type":"education","lineage":["https://openalex.org/I133868755","https://openalex.org/I24943067"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210093194","display_name":"Fudan University Shanghai Cancer Center","ror":"https://ror.org/00my25942","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093194"]},{"id":"https://openalex.org/I4391768195","display_name":"State Key Laboratory of Medical Neurobiology","ror":"https://ror.org/00nn53y54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I24943067","https://openalex.org/I4391768195"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ru Zhao","raw_affiliation_strings":["Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences and School of Basic Medical Sciences; Cancer Institutes, Key Laboratory of Breast Cancer in Shanghai; Shanghai Key Laboratory of Radiation Oncology; The Shanghai Key Laboratory of Medical Epigenetics, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences and School of Basic Medical Sciences; Cancer Institutes, Key Laboratory of Breast Cancer in Shanghai; Shanghai Key Laboratory of Radiation Oncology; The Shanghai Key Laboratory of Medical Epigenetics, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I133868755","https://openalex.org/I24943067","https://openalex.org/I4210093194","https://openalex.org/I4391768195"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xiao-Lin Guan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I133868755","display_name":"Shanghai Medical College of Fudan University","ror":"https://ror.org/01zntxs11","country_code":"CN","type":"education","lineage":["https://openalex.org/I133868755","https://openalex.org/I24943067"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210093194","display_name":"Fudan University Shanghai Cancer Center","ror":"https://ror.org/00my25942","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093194"]},{"id":"https://openalex.org/I4391768195","display_name":"State Key Laboratory of Medical Neurobiology","ror":"https://ror.org/00nn53y54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I24943067","https://openalex.org/I4391768195"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiao-Lin Guan","raw_affiliation_strings":["Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences and School of Basic Medical Sciences; Cancer Institutes, Key Laboratory of Breast Cancer in Shanghai; Shanghai Key Laboratory of Radiation Oncology; The Shanghai Key Laboratory of Medical Epigenetics, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences and School of Basic Medical Sciences; Cancer Institutes, Key Laboratory of Breast Cancer in Shanghai; Shanghai Key Laboratory of Radiation Oncology; The Shanghai Key Laboratory of Medical Epigenetics, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I133868755","https://openalex.org/I24943067","https://openalex.org/I4210093194","https://openalex.org/I4391768195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050533328","display_name":"Miao-Lin Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I133868755","display_name":"Shanghai Medical College of Fudan University","ror":"https://ror.org/01zntxs11","country_code":"CN","type":"education","lineage":["https://openalex.org/I133868755","https://openalex.org/I24943067"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210093194","display_name":"Fudan University Shanghai Cancer Center","ror":"https://ror.org/00my25942","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093194"]},{"id":"https://openalex.org/I4391768195","display_name":"State Key Laboratory of Medical Neurobiology","ror":"https://ror.org/00nn53y54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I24943067","https://openalex.org/I4391768195"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Miao-Lin Li","raw_affiliation_strings":["Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences and School of Basic Medical Sciences; Cancer Institutes, Key Laboratory of Breast Cancer in Shanghai; Shanghai Key Laboratory of Radiation Oncology; The Shanghai Key Laboratory of Medical Epigenetics, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences and School of Basic Medical Sciences; Cancer Institutes, Key Laboratory of Breast Cancer in Shanghai; Shanghai Key Laboratory of Radiation Oncology; The Shanghai Key Laboratory of Medical Epigenetics, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I133868755","https://openalex.org/I24943067","https://openalex.org/I4210093194","https://openalex.org/I4391768195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065523443","display_name":"Fan Zhang","orcid":"https://orcid.org/0000-0002-6102-2970","observed_orcids":["https://orcid.org/0000-0002-6102-2970"]},"institutions":[{"id":"https://openalex.org/I133868755","display_name":"Shanghai Medical College of Fudan University","ror":"https://ror.org/01zntxs11","country_code":"CN","type":"education","lineage":["https://openalex.org/I133868755","https://openalex.org/I24943067"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210093194","display_name":"Fudan University Shanghai Cancer Center","ror":"https://ror.org/00my25942","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093194"]},{"id":"https://openalex.org/I4391768195","display_name":"State Key Laboratory of Medical Neurobiology","ror":"https://ror.org/00nn53y54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I24943067","https://openalex.org/I4391768195"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fan Zhang","raw_affiliation_strings":["Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences and School of Basic Medical Sciences; Cancer Institutes, Key Laboratory of Breast Cancer in Shanghai; Shanghai Key Laboratory of Radiation Oncology; The Shanghai Key Laboratory of Medical Epigenetics, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences and School of Basic Medical Sciences; Cancer Institutes, Key Laboratory of Breast Cancer in Shanghai; Shanghai Key Laboratory of Radiation Oncology; The Shanghai Key Laboratory of Medical Epigenetics, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I133868755","https://openalex.org/I24943067","https://openalex.org/I4210093194","https://openalex.org/I4391768195"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Zhi-Han Wan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I133868755","display_name":"Shanghai Medical College of Fudan University","ror":"https://ror.org/01zntxs11","country_code":"CN","type":"education","lineage":["https://openalex.org/I133868755","https://openalex.org/I24943067"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210093194","display_name":"Fudan University Shanghai Cancer Center","ror":"https://ror.org/00my25942","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093194"]},{"id":"https://openalex.org/I4391768195","display_name":"State Key Laboratory of Medical Neurobiology","ror":"https://ror.org/00nn53y54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I24943067","https://openalex.org/I4391768195"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhi-Han Wan","raw_affiliation_strings":["Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences and School of Basic Medical Sciences; Cancer Institutes, Key Laboratory of Breast Cancer in Shanghai; Shanghai Key Laboratory of Radiation Oncology; The Shanghai Key Laboratory of Medical Epigenetics, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences and School of Basic Medical Sciences; Cancer Institutes, Key Laboratory of Breast Cancer in Shanghai; Shanghai Key Laboratory of Radiation Oncology; The Shanghai Key Laboratory of Medical Epigenetics, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I133868755","https://openalex.org/I24943067","https://openalex.org/I4210093194","https://openalex.org/I4391768195"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jing-Xuan Feng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I133868755","display_name":"Shanghai Medical College of Fudan University","ror":"https://ror.org/01zntxs11","country_code":"CN","type":"education","lineage":["https://openalex.org/I133868755","https://openalex.org/I24943067"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210093194","display_name":"Fudan University Shanghai Cancer Center","ror":"https://ror.org/00my25942","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093194"]},{"id":"https://openalex.org/I4391768195","display_name":"State Key Laboratory of Medical Neurobiology","ror":"https://ror.org/00nn53y54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I24943067","https://openalex.org/I4391768195"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing-Xuan Feng","raw_affiliation_strings":["Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences and School of Basic Medical Sciences; Cancer Institutes, Key Laboratory of Breast Cancer in Shanghai; Shanghai Key Laboratory of Radiation Oncology; The Shanghai Key Laboratory of Medical Epigenetics, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences and School of Basic Medical Sciences; Cancer Institutes, Key Laboratory of Breast Cancer in Shanghai; Shanghai Key Laboratory of Radiation Oncology; The Shanghai Key Laboratory of Medical Epigenetics, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China","institution_ids":["https://openalex.org/I133868755","https://openalex.org/I24943067","https://openalex.org/I4210093194","https://openalex.org/I4391768195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014700415","display_name":"Miao Yin","orcid":"https://orcid.org/0000-0001-7026-7067","observed_orcids":["https://orcid.org/0000-0001-7026-7067"]},"institutions":[{"id":"https://openalex.org/I133868755","display_name":"Shanghai Medical College of Fudan University","ror":"https://ror.org/01zntxs11","country_code":"CN","type":"education","lineage":["https://openalex.org/I133868755","https://openalex.org/I24943067"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210093194","display_name":"Fudan University Shanghai Cancer Center","ror":"https://ror.org/00my25942","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093194"]},{"id":"https://openalex.org/I4391768195","display_name":"State Key Laboratory of Medical Neurobiology","ror":"https://ror.org/00nn53y54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I24943067","https://openalex.org/I4391768195"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Miao Yin","raw_affiliation_strings":["Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences and School of Basic Medical Sciences; Cancer Institutes, Key Laboratory of Breast Cancer in Shanghai; Shanghai Key Laboratory of Radiation Oncology; The Shanghai Key Laboratory of Medical Epigenetics, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address: miaoyin@fudan.edu.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences and School of Basic Medical Sciences; Cancer Institutes, Key Laboratory of Breast Cancer in Shanghai; Shanghai Key Laboratory of Radiation Oncology; The Shanghai Key Laboratory of Medical Epigenetics, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address: miaoyin@fudan.edu.cn","institution_ids":["https://openalex.org/I133868755","https://openalex.org/I24943067","https://openalex.org/I4210093194","https://openalex.org/I4391768195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086236254","display_name":"Qun\u2010Ying Lei","orcid":"https://orcid.org/0000-0002-8547-8518","observed_orcids":["https://orcid.org/0000-0002-8547-8518"]},"institutions":[{"id":"https://openalex.org/I133868755","display_name":"Shanghai Medical College of Fudan University","ror":"https://ror.org/01zntxs11","country_code":"CN","type":"education","lineage":["https://openalex.org/I133868755","https://openalex.org/I24943067"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210093194","display_name":"Fudan University Shanghai Cancer Center","ror":"https://ror.org/00my25942","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093194"]},{"id":"https://openalex.org/I4391768195","display_name":"State Key Laboratory of Medical Neurobiology","ror":"https://ror.org/00nn53y54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I24943067","https://openalex.org/I4391768195"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Qun-Ying Lei","raw_affiliation_strings":["Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences and School of Basic Medical Sciences; Cancer Institutes, Key Laboratory of Breast Cancer in Shanghai; Shanghai Key Laboratory of Radiation Oncology; The Shanghai Key Laboratory of Medical Epigenetics, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China; New Cornerstone Science Laboratory, School of Basic Medical Sciences, Fudan University, Shanghai, China. Electronic address: qlei@fudan.edu.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences and School of Basic Medical Sciences; Cancer Institutes, Key Laboratory of Breast Cancer in Shanghai; Shanghai Key Laboratory of Radiation Oncology; The Shanghai Key Laboratory of Medical Epigenetics, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China; New Cornerstone Science Laboratory, School of Basic Medical Sciences, Fudan University, Shanghai, China. Electronic address: qlei@fudan.edu.cn","institution_ids":["https://openalex.org/I133868755","https://openalex.org/I24943067","https://openalex.org/I4210093194","https://openalex.org/I4391768195"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091559422","display_name":"Qixiang Ma","orcid":"https://orcid.org/0000-0002-4760-5176","observed_orcids":["https://orcid.org/0000-0002-4760-5176"]},"institutions":[{"id":"https://openalex.org/I133868755","display_name":"Shanghai Medical College of Fudan University","ror":"https://ror.org/01zntxs11","country_code":"CN","type":"education","lineage":["https://openalex.org/I133868755","https://openalex.org/I24943067"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210093194","display_name":"Fudan University Shanghai Cancer Center","ror":"https://ror.org/00my25942","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093194"]},{"id":"https://openalex.org/I4391768195","display_name":"State Key Laboratory of Medical Neurobiology","ror":"https://ror.org/00nn53y54","country_code":"CN","type":"facility","lineage":["https://openalex.org/I24943067","https://openalex.org/I4391768195"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Qi-Xiang Ma","raw_affiliation_strings":["Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences and School of Basic Medical Sciences; Cancer Institutes, Key Laboratory of Breast Cancer in Shanghai; Shanghai Key Laboratory of Radiation Oncology; The Shanghai Key Laboratory of Medical Epigenetics, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address: maqixiang@fudan.edu.cn"],"raw_orcid":"https://orcid.org/0000-0002-4760-5176","affiliations":[{"raw_affiliation_string":"Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences and School of Basic Medical Sciences; Cancer Institutes, Key Laboratory of Breast Cancer in Shanghai; Shanghai Key Laboratory of Radiation Oncology; The Shanghai Key Laboratory of Medical Epigenetics, State Key Laboratory of Medical Neurobiology, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address: maqixiang@fudan.edu.cn","institution_ids":["https://openalex.org/I133868755","https://openalex.org/I24943067","https://openalex.org/I4210093194","https://openalex.org/I4391768195"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5014700415","https://openalex.org/A5086236254","https://openalex.org/A5091559422"],"corresponding_institution_ids":["https://openalex.org/I133868755","https://openalex.org/I24943067","https://openalex.org/I4210093194","https://openalex.org/I4391768195"],"apc_list":{"value":10400,"currency":"USD","value_usd":10400},"apc_paid":null,"fwci":5.7416,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.97708435,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"85","issue":"13","first_page":"2581","last_page":"2596.e6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12770","display_name":"Amino Acid Enzymes and Metabolism","score":0.4560999870300293,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12770","display_name":"Amino Acid Enzymes and Metabolism","score":0.4560999870300293,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10631","display_name":"Cancer, Hypoxia, and Metabolism","score":0.06849999725818634,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10929","display_name":"Wnt/\u03b2-catenin signaling in development and cancer","score":0.051100000739097595,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bag2","display_name":"BAG2","score":0.9940000176429749},{"id":"https://openalex.org/keywords/arginine-sensing","display_name":"arginine sensing","score":0.8479999899864197},{"id":"https://openalex.org/keywords/arginine-deficiency","display_name":"arginine deficiency","score":0.9639999866485596},{"id":"https://openalex.org/keywords/nutrient-stress","display_name":"nutritional stress","score":0.5479999780654907},{"id":"https://openalex.org/keywords/beta-catenin-degradation","display_name":"\u03b2-catenin degradation","score":0.8339999914169312},{"id":"https://openalex.org/keywords/wnt-beta-catenin-signaling","display_name":"Wnt/\u03b2-catenin signaling","score":0.9309999942779541},{"id":"https://openalex.org/keywords/atf4","display_name":"ATF4","score":0.9359999895095825},{"id":"https://openalex.org/keywords/tumor-cell-survival","display_name":"tumor cell survival","score":0.7020000219345093},{"id":"https://openalex.org/keywords/molecular-chaperones","display_name":"molecular chaperones","score":0.6830000281333923},{"id":"https://openalex.org/keywords/tumor-cell-adaptation","display_name":"tumor cell adaptation","score":0.4959999918937683}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9363633990287781},{"id":"https://openalex.org/C2777468819","wikidata":"https://www.wikidata.org/wiki/Q173670","display_name":"Arginine","level":3,"score":0.6706680655479431},{"id":"https://openalex.org/C3019137385","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell survival","level":3,"score":0.46482613682746887},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.46428027749061584},{"id":"https://openalex.org/C3020616263","wikidata":"https://www.wikidata.org/wiki/Q1216998","display_name":"Tumor cells","level":2,"score":0.4162621796131134},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.37314608693122864},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.26534903049468994},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.1338220238685608},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.11001789569854736}],"mesh":[{"descriptor_ui":"D001120","descriptor_name":"Arginine","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":true},{"descriptor_ui":"D001120","descriptor_name":"Arginine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018832","descriptor_name":"Molecular Chaperones","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051176","descriptor_name":"beta Catenin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051176","descriptor_name":"beta Catenin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051701","descriptor_name":"Activating Transcription Factor 4","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D051701","descriptor_name":"Activating Transcription Factor 4","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D057809","descriptor_name":"HEK293 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059748","descriptor_name":"Proteolysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060449","descriptor_name":"Wnt Signaling Pathway","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.molcel.2025.05.035","doi":"https://doi.org/10.1016/j.molcel.2025.05.035","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.molcel.2025.05.035","pdf_url":null,"source":{"id":"https://openalex.org/S156208185","display_name":"Molecular Cell","issn_l":"1097-2765","issn":["1097-2765","1097-4164"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Cell","raw_type":"journal-article"},{"id":"pmid:40555234","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40555234","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular cell","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8048999905586243}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1462067747","display_name":null,"funder_award_id":"82472873","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G1526153549","display_name":null,"funder_award_id":"82372827","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3793235242","display_name":null,"funder_award_id":"82330092","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G478382699","display_name":null,"funder_award_id":"2020YFA0803402","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5537129584","display_name":null,"funder_award_id":"82121004","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G755278505","display_name":null,"funder_award_id":"2020YFA0803402","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G8703454352","display_name":null,"funder_award_id":"2023ZKZD11","funder_id":"https://openalex.org/F4320321881","funder_display_name":"Shanghai Municipal Education Commission"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321851","display_name":"Fudan University","ror":"https://ror.org/013q1eq08"},{"id":"https://openalex.org/F4320321881","display_name":"Shanghai Municipal Education Commission","ror":"https://ror.org/05tewj457"},{"id":"https://openalex.org/F4320321885","display_name":"Science and Technology Commission of Shanghai Municipality","ror":"https://ror.org/03kt66j61"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":57,"referenced_works":["https://openalex.org/W1969717239","https://openalex.org/W2006419043","https://openalex.org/W2009578813","https://openalex.org/W2014177895","https://openalex.org/W2027169351","https://openalex.org/W2027409371","https://openalex.org/W2029569943","https://openalex.org/W2040942754","https://openalex.org/W2041076445","https://openalex.org/W2062934426","https://openalex.org/W2067924267","https://openalex.org/W2071146934","https://openalex.org/W2084952088","https://openalex.org/W2105668062","https://openalex.org/W2113709638","https://openalex.org/W2127848114","https://openalex.org/W2136452399","https://openalex.org/W2166063624","https://openalex.org/W2169344296","https://openalex.org/W2252568502","https://openalex.org/W2262414037","https://openalex.org/W2293646973","https://openalex.org/W2512678052","https://openalex.org/W2518959324","https://openalex.org/W2555868191","https://openalex.org/W2580528384","https://openalex.org/W2582453508","https://openalex.org/W2765934351","https://openalex.org/W2772417595","https://openalex.org/W2801733864","https://openalex.org/W2808082897","https://openalex.org/W2890204638","https://openalex.org/W2896968374","https://openalex.org/W2911986456","https://openalex.org/W2970045605","https://openalex.org/W3045735973","https://openalex.org/W3128335178","https://openalex.org/W3142100769","https://openalex.org/W3156827665","https://openalex.org/W3160345772","https://openalex.org/W3195892274","https://openalex.org/W4220798004","https://openalex.org/W4281687889","https://openalex.org/W4285405627","https://openalex.org/W4313706713","https://openalex.org/W4319030306","https://openalex.org/W4321014279","https://openalex.org/W4360609580","https://openalex.org/W4387408542","https://openalex.org/W4390937511","https://openalex.org/W4391839962","https://openalex.org/W4392624455","https://openalex.org/W4392971016","https://openalex.org/W4393109136","https://openalex.org/W6790544456","https://openalex.org/W6794468620","https://openalex.org/W6850482386"],"related_works":["https://openalex.org/W4411986376","https://openalex.org/W4323038012","https://openalex.org/W2221373272","https://openalex.org/W4406646517","https://openalex.org/W3123704882","https://openalex.org/W2810450902","https://openalex.org/W2342912708","https://openalex.org/W7167790516","https://openalex.org/W4409591659","https://openalex.org/W4284698831"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":11},{"year":2025,"cited_by_count":7}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2025-10-10T00:00:00"}