{"id":"https://openalex.org/W4411535974","doi":"https://doi.org/10.1093/oncolo/oyaf127","title":"Clinical outcome and deep learning imaging characteristics of patients treated by radio-chemotherapy for a \u201cmolecular\u201d glioblastoma","display_name":"Clinical outcome and deep learning imaging characteristics of patients treated by radio-chemotherapy for a \u201cmolecular\u201d glioblastoma","publication_year":2025,"publication_date":"2025-05-16","ids":{"openalex":"https://openalex.org/W4411535974","doi":"https://doi.org/10.1093/oncolo/oyaf127","pmid":"https://pubmed.ncbi.nlm.nih.gov/40542584","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12204753"},"language":"en","primary_location":{"id":"doi:10.1093/oncolo/oyaf127","doi":"https://doi.org/10.1093/oncolo/oyaf127","is_oa":true,"landing_page_url":"https://doi.org/10.1093/oncolo/oyaf127","pdf_url":null,"source":{"id":"https://openalex.org/S15523509","display_name":"The Oncologist","issn_l":"1083-7159","issn":["1083-7159","1549-490X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316295","host_organization_name":"AlphaMed Press","host_organization_lineage":["https://openalex.org/P4310316295"],"host_organization_lineage_names":["AlphaMed Press"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Oncologist","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1093/oncolo/oyaf127","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5116170331","display_name":"Caroline Zerbib","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210098740","display_name":"Institut universitaire du cancer de Toulouse Oncopole","ror":"https://ror.org/014hxhm89","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3019448017","https://openalex.org/I4210098740","https://openalex.org/I4210128666"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Caroline Zerbib","raw_affiliation_strings":["Department of Radiation Oncology, Institut Universitaire du Cancer de Toulouse Oncopole , Oncopole Claudius Regaud, 31059 Toulouse Cedex 1 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Institut Universitaire du Cancer de Toulouse Oncopole , Oncopole Claudius Regaud, 31059 Toulouse Cedex 1 ,","institution_ids":["https://openalex.org/I4210098740"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056030375","display_name":"Lucas Robinet","orcid":"https://orcid.org/0000-0001-8796-8361","observed_orcids":["https://orcid.org/0000-0001-8796-8361"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210087620","display_name":"Centre de Recherches en Canc\u00e9rologie de Toulouse","ror":"https://ror.org/003412r28","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210087620","https://openalex.org/I4405258862"]},{"id":"https://openalex.org/I4210098740","display_name":"Institut universitaire du cancer de Toulouse Oncopole","ror":"https://ror.org/014hxhm89","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3019448017","https://openalex.org/I4210098740","https://openalex.org/I4210128666"]},{"id":"https://openalex.org/I4394709072","display_name":"IRT Saint Exup\u00e9ry","ror":"https://ror.org/01qew1n19","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4394709072"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Lucas Robinet","raw_affiliation_strings":["Department of Radiation Oncology, Institut Universitaire du Cancer de Toulouse Oncopole , Oncopole Claudius Regaud, 31059 Toulouse Cedex 1 ,","INSERM UMR 1037, Cancer Research Center of Toulouse (CRCT) , 31037 Toulouse Cedex 1 ,","IRT Saint-Exup\u00e9ry , 31400 Toulouse ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Institut Universitaire du Cancer de Toulouse Oncopole , Oncopole Claudius Regaud, 31059 Toulouse Cedex 1 ,","institution_ids":["https://openalex.org/I4210098740"]},{"raw_affiliation_string":"INSERM UMR 1037, Cancer Research Center of Toulouse (CRCT) , 31037 Toulouse Cedex 1 ,","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210087620"]},{"raw_affiliation_string":"IRT Saint-Exup\u00e9ry , 31400 Toulouse ,","institution_ids":["https://openalex.org/I4394709072"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029499960","display_name":"Soleakhena Ken","orcid":"https://orcid.org/0000-0001-7904-5882","observed_orcids":["https://orcid.org/0000-0001-7904-5882"]},"institutions":[{"id":"https://openalex.org/I4210098740","display_name":"Institut universitaire du cancer de Toulouse Oncopole","ror":"https://ror.org/014hxhm89","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3019448017","https://openalex.org/I4210098740","https://openalex.org/I4210128666"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Soleakhena Ken","raw_affiliation_strings":["Department of Engineering and Medical Physics, Institut Universitaire du Cancer Toulouse Oncopole, Oncopole Claudius Regaud , 31059 Toulouse Cedex 1 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Engineering and Medical Physics, Institut Universitaire du Cancer Toulouse Oncopole, Oncopole Claudius Regaud , 31059 Toulouse Cedex 1 ,","institution_ids":["https://openalex.org/I4210098740"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072191467","display_name":"Ana Cavillon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210098740","display_name":"Institut universitaire du cancer de Toulouse Oncopole","ror":"https://ror.org/014hxhm89","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3019448017","https://openalex.org/I4210098740","https://openalex.org/I4210128666"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Ana Cavillon","raw_affiliation_strings":["Biostatistics & Health Data Science Unit, Oncopole Claudius Regaud, IUCT-Oncopole , 31059 Toulouse ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biostatistics & Health Data Science Unit, Oncopole Claudius Regaud, IUCT-Oncopole , 31059 Toulouse ,","institution_ids":["https://openalex.org/I4210098740"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045745156","display_name":"Margaux Roques","orcid":"https://orcid.org/0000-0001-9447-3092","observed_orcids":["https://orcid.org/0000-0001-9447-3092"]},"institutions":[{"id":"https://openalex.org/I4210138343","display_name":"H\u00f4pital Purpan","ror":"https://ror.org/03vcx3f97","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3019448017","https://openalex.org/I4210138343"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Margaux Roques","raw_affiliation_strings":["Department of Neuroradiology, Hopital Pierre Paul Riquet, CHU Purpan , 31300 Toulouse ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroradiology, Hopital Pierre Paul Riquet, CHU Purpan , 31300 Toulouse ,","institution_ids":["https://openalex.org/I4210138343"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065733313","display_name":"Delphine Larrieu Ciron","orcid":"https://orcid.org/0000-0002-0478-7774","observed_orcids":["https://orcid.org/0000-0002-0478-7774"]},"institutions":[{"id":"https://openalex.org/I4210098740","display_name":"Institut universitaire du cancer de Toulouse Oncopole","ror":"https://ror.org/014hxhm89","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3019448017","https://openalex.org/I4210098740","https://openalex.org/I4210128666"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Delphine Larrieu","raw_affiliation_strings":["Department of Medical Oncology & Clinical Research Unit, Institut Universitaire du Cancer de Toulouse-Oncopole , 31059 Toulouse Cedex 1 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology & Clinical Research Unit, Institut Universitaire du Cancer de Toulouse-Oncopole , 31059 Toulouse Cedex 1 ,","institution_ids":["https://openalex.org/I4210098740"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086050016","display_name":"Aurore Siegfried","orcid":"https://orcid.org/0000-0001-9152-4616","observed_orcids":["https://orcid.org/0000-0001-9152-4616"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I3019448017","display_name":"Centre Hospitalier Universitaire de Toulouse","ror":"https://ror.org/017h5q109","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3019448017"]},{"id":"https://openalex.org/I4210087620","display_name":"Centre de Recherches en Canc\u00e9rologie de Toulouse","ror":"https://ror.org/003412r28","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210087620","https://openalex.org/I4405258862"]},{"id":"https://openalex.org/I4210098740","display_name":"Institut universitaire du cancer de Toulouse Oncopole","ror":"https://ror.org/014hxhm89","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3019448017","https://openalex.org/I4210098740","https://openalex.org/I4210128666"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Aurore Siegfried","raw_affiliation_strings":["INSERM UMR 1037, Cancer Research Center of Toulouse (CRCT) , 31037 Toulouse Cedex 1 ,","Pathology and Cytology Department, CHU Toulouse, IUCT Oncopole , 31100 Toulouse ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM UMR 1037, Cancer Research Center of Toulouse (CRCT) , 31037 Toulouse Cedex 1 ,","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210087620"]},{"raw_affiliation_string":"Pathology and Cytology Department, CHU Toulouse, IUCT Oncopole , 31100 Toulouse ,","institution_ids":["https://openalex.org/I3019448017","https://openalex.org/I4210098740"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047909362","display_name":"Franck\u2013Emmanuel Roux","orcid":"https://orcid.org/0000-0002-4209-7117","observed_orcids":["https://orcid.org/0000-0002-4209-7117"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I134560555","display_name":"Universit\u00e9 Toulouse III - Paul Sabatier","ror":"https://ror.org/02v6kpv12","country_code":"FR","type":"education","lineage":["https://openalex.org/I134560555","https://openalex.org/I4405258862"]},{"id":"https://openalex.org/I4210138343","display_name":"H\u00f4pital Purpan","ror":"https://ror.org/03vcx3f97","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3019448017","https://openalex.org/I4210138343"]},{"id":"https://openalex.org/I4210145991","display_name":"Centre de recherche cerveau et cognition","ror":"https://ror.org/04fhrs205","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4210096427","https://openalex.org/I4210145991","https://openalex.org/I4405258862"]},{"id":"https://openalex.org/I4405258862","display_name":"Universit\u00e9 de Toulouse","ror":"https://ror.org/01ahyrz84","country_code":"FR","type":"education","lineage":["https://openalex.org/I4405258862"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Franck Emmanuel Roux","raw_affiliation_strings":["CerCo, Universit\u00e9 de Toulouse, CNRS, UPS, CHU Purpan , Toulouse ,","Department of Neurosurgery, Hopital Pierre Paul Riquet, CHU Purpan , 31300 Toulouse ,","University Toulouse III Paul Sabatier , 31400 Toulouse ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CerCo, Universit\u00e9 de Toulouse, CNRS, UPS, CHU Purpan , Toulouse ,","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I134560555","https://openalex.org/I4210145991","https://openalex.org/I4405258862"]},{"raw_affiliation_string":"Department of Neurosurgery, Hopital Pierre Paul Riquet, CHU Purpan , 31300 Toulouse ,","institution_ids":["https://openalex.org/I4210138343"]},{"raw_affiliation_string":"University Toulouse III Paul Sabatier , 31400 Toulouse ,","institution_ids":["https://openalex.org/I134560555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058626947","display_name":"Ahmad Berjaoui","orcid":"https://orcid.org/0000-0002-3930-1543","observed_orcids":["https://orcid.org/0000-0002-3930-1543"]},"institutions":[{"id":"https://openalex.org/I4394709072","display_name":"IRT Saint Exup\u00e9ry","ror":"https://ror.org/01qew1n19","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I4394709072"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Ahmad Berjaoui","raw_affiliation_strings":["IRT Saint-Exup\u00e9ry , 31400 Toulouse ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IRT Saint-Exup\u00e9ry , 31400 Toulouse ,","institution_ids":["https://openalex.org/I4394709072"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041166804","display_name":"Elizabeth Cohen\u2010Jonathan Moyal","orcid":"https://orcid.org/0000-0002-6593-9276","observed_orcids":["https://orcid.org/0000-0002-6593-9276"]},"institutions":[{"id":"https://openalex.org/I134560555","display_name":"Universit\u00e9 Toulouse III - Paul Sabatier","ror":"https://ror.org/02v6kpv12","country_code":"FR","type":"education","lineage":["https://openalex.org/I134560555","https://openalex.org/I4405258862"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210087620","display_name":"Centre de Recherches en Canc\u00e9rologie de Toulouse","ror":"https://ror.org/003412r28","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I4210087620","https://openalex.org/I4405258862"]},{"id":"https://openalex.org/I4210098740","display_name":"Institut universitaire du cancer de Toulouse Oncopole","ror":"https://ror.org/014hxhm89","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I3019448017","https://openalex.org/I4210098740","https://openalex.org/I4210128666"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Elizabeth Cohen-Jonathan Moyal","raw_affiliation_strings":["Department of Radiation Oncology, Institut Universitaire du Cancer de Toulouse Oncopole , Oncopole Claudius Regaud, 31059 Toulouse Cedex 1 ,","INSERM UMR 1037, Cancer Research Center of Toulouse (CRCT) , 31037 Toulouse Cedex 1 ,","University Toulouse III Paul Sabatier , 31400 Toulouse ,"],"raw_orcid":"https://orcid.org/0000-0002-6593-9276","affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Institut Universitaire du Cancer de Toulouse Oncopole , Oncopole Claudius Regaud, 31059 Toulouse Cedex 1 ,","institution_ids":["https://openalex.org/I4210098740"]},{"raw_affiliation_string":"INSERM UMR 1037, Cancer Research Center of Toulouse (CRCT) , 31037 Toulouse Cedex 1 ,","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210087620"]},{"raw_affiliation_string":"University Toulouse III Paul Sabatier , 31400 Toulouse ,","institution_ids":["https://openalex.org/I134560555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5041166804"],"corresponding_institution_ids":["https://openalex.org/I134560555","https://openalex.org/I154526488","https://openalex.org/I4210087620","https://openalex.org/I4210098740"],"apc_list":{"value":3852,"currency":"USD","value_usd":3852},"apc_paid":{"value":3852,"currency":"USD","value_usd":3852},"fwci":1.6359,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.84568276,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":98},"biblio":{"volume":"30","issue":"6","first_page":"oyaf127","last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/contrast-enhancement","display_name":"contrast enhancement","score":0.6290000081062317},{"id":"https://openalex.org/keywords/low-grade-glioma","display_name":"low-grade glioma","score":0.7540000081062317},{"id":"https://openalex.org/keywords/deep-learning","display_name":"deep learning","score":0.5609999895095825},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"artificial intelligence","score":0.6179999709129333},{"id":"https://openalex.org/keywords/temozolomide","display_name":"temozolomide","score":0.8510000109672546},{"id":"https://openalex.org/keywords/radiotherapy","display_name":"radiotherapy","score":0.7559999823570251},{"id":"https://openalex.org/keywords/survival-outcomes","display_name":"survival outcomes","score":0.6959999799728394},{"id":"https://openalex.org/keywords/egfr-amplification","display_name":"EGFR amplification","score":0.8889999985694885},{"id":"https://openalex.org/keywords/tert-mutation","display_name":"TERT mutation","score":0.8519999980926514}],"concepts":[{"id":"https://openalex.org/C2776194525","wikidata":"https://www.wikidata.org/wiki/Q282142","display_name":"Glioblastoma","level":2,"score":0.7945839166641235},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.6119611859321594},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5367283821105957},{"id":"https://openalex.org/C148220186","wikidata":"https://www.wikidata.org/wiki/Q7111912","display_name":"Outcome (game theory)","level":2,"score":0.4795924723148346},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4487815499305725},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.41001370549201965},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.19467487931251526},{"id":"https://openalex.org/C144237770","wikidata":"https://www.wikidata.org/wiki/Q747534","display_name":"Mathematical economics","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000077204","descriptor_name":"Temozolomide","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005909","descriptor_name":"Glioblastoma","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D005909","descriptor_name":"Glioblastoma","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D005909","descriptor_name":"Glioblastoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005909","descriptor_name":"Glioblastoma","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D005909","descriptor_name":"Glioblastoma","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059248","descriptor_name":"Chemoradiotherapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1093/oncolo/oyaf127","doi":"https://doi.org/10.1093/oncolo/oyaf127","is_oa":true,"landing_page_url":"https://doi.org/10.1093/oncolo/oyaf127","pdf_url":null,"source":{"id":"https://openalex.org/S15523509","display_name":"The Oncologist","issn_l":"1083-7159","issn":["1083-7159","1549-490X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316295","host_organization_name":"AlphaMed Press","host_organization_lineage":["https://openalex.org/P4310316295"],"host_organization_lineage_names":["AlphaMed Press"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Oncologist","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12204753","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12204753","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncologist","raw_type":"Text"},{"id":"pmid:40542584","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40542584","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The oncologist","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-05551502v1","doi":null,"is_oa":true,"landing_page_url":"https://ut-toulouseinp.hal.science/hal-05551502","pdf_url":"https://ut3-toulouseinp.hal.science/hal-05551502v1/file/Zerbib_2025.pdf","source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The Oncologist, 2025, 30 (6), pp.oyaf127. ⟨10.1093/oncolo/oyaf127⟩","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1093/oncolo/oyaf127","doi":"https://doi.org/10.1093/oncolo/oyaf127","is_oa":true,"landing_page_url":"https://doi.org/10.1093/oncolo/oyaf127","pdf_url":null,"source":{"id":"https://openalex.org/S15523509","display_name":"The Oncologist","issn_l":"1083-7159","issn":["1083-7159","1549-490X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316295","host_organization_name":"AlphaMed Press","host_organization_lineage":["https://openalex.org/P4310316295"],"host_organization_lineage_names":["AlphaMed Press"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Oncologist","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4411535974.pdf","grobid_xml":"https://content.openalex.org/works/W4411535974.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W564708804","https://openalex.org/W2096287682","https://openalex.org/W2098812986","https://openalex.org/W2106235379","https://openalex.org/W2107007091","https://openalex.org/W2151140401","https://openalex.org/W2559580777","https://openalex.org/W2608192684","https://openalex.org/W2746507800","https://openalex.org/W2755791336","https://openalex.org/W2767128594","https://openalex.org/W2778283729","https://openalex.org/W2806986802","https://openalex.org/W2887482411","https://openalex.org/W2891763428","https://openalex.org/W2894102714","https://openalex.org/W2901381629","https://openalex.org/W2958189178","https://openalex.org/W2968446587","https://openalex.org/W2970963176","https://openalex.org/W2981544544","https://openalex.org/W2995455068","https://openalex.org/W3013214688","https://openalex.org/W3017712284","https://openalex.org/W3023290769","https://openalex.org/W3122182813","https://openalex.org/W3133559404","https://openalex.org/W3167188261","https://openalex.org/W3174246647","https://openalex.org/W3185961698","https://openalex.org/W4280648692","https://openalex.org/W4303969137","https://openalex.org/W4320817853","https://openalex.org/W4365452787","https://openalex.org/W4381683526"],"related_works":["https://openalex.org/W4391308593","https://openalex.org/W7201855129","https://openalex.org/W4413048304","https://openalex.org/W7221609934","https://openalex.org/W7118896582","https://openalex.org/W3207581335","https://openalex.org/W4386537768","https://openalex.org/W4212813351","https://openalex.org/W4410548973","https://openalex.org/W2953738303"],"abstract_inverted_index":{"BACKGROUND:":[0],"Since":[1],"2021,":[2],"glioblastomas":[3,11,33],"have":[4,208,219],"been":[5],"classified":[6],"into":[7],"two":[8],"subgroups:":[9],"classic":[10],"(histGB),":[12],"defined":[13],"as":[14],"IDH":[15],"wild-type":[16],"grade":[17],"4":[18],"astrocytomas":[19],"with":[20,106,204,213],"necrosis":[21],"and":[22,31,53,79,86,108,116,168,206],"vascular":[23],"proliferation,":[24],"showing":[25],"contrast":[26],"enhancement":[27],"(CE)":[28],"on":[29,96],"MRI;":[30],"molecular":[32],"(molGB),":[34],"characterized":[35],"by":[36],"specific":[37],"alterations":[38],"(7+/10-,":[39],"EGFR":[40],"amplification,":[41],"TERT":[42],"mutation).":[43],"Although":[44],"not":[45],"always":[46],"the":[47,61,72,81,111],"case,":[48],"molGB":[49,75,91,133,167,171,189,205,214,227],"often":[50],"lack":[51],"CE":[52,93,135,173,191,216],"may":[54],"mimic":[55],"low-grade":[56],"gliomas":[57],"(LGG),":[58],"hence":[59],"complicating":[60],"diagnosis.":[62],"Survival":[63],"outcomes":[64,113],"remain":[65],"debated.":[66],"This":[67],"study":[68],"aimed":[69],"to":[70,76,89,131,218],"evaluate":[71],"response":[73],"of":[74,83,114,199],"standard":[77],"treatment":[78],"assess":[80],"ability":[82],"machine":[84],"learning":[85,88],"deep":[87],"differentiate":[90,226],"without":[92,134,172,190,215],"from":[94,126,136,192,228],"LGG":[95],"MRI.":[97],"METHODS:":[98],"We":[99],"retrospectively":[100],"studied":[101],"132":[102],"glioblastoma":[103],"patients":[104,203,212],"treated":[105],"radiotherapy":[107],"temozolomide,":[109],"comparing":[110],"survival":[112,145,156],"histGB":[115,207],"molGB.":[117],"Artificial":[118,185,222],"intelligence":[119,186,223],"(AI)":[120],"models":[121,187,224],"were":[122],"trained":[123],"using":[124],"features":[125],"MRI":[127],"FLAIR":[128],"hypersignal":[129],"segmentation":[130],"distinguish":[132],"LGG.":[137],"RESULTS:":[138],"No":[139],"significant":[140],"difference":[141],"in":[142],"median":[143,176],"overall":[144,210],"(OS)":[146],"(20.6":[147],"vs":[148,158,179],"18.4":[149],"months,":[150,160,181],"P":[151,161],"=":[152,162],".2)":[153],"or":[154],"progression-free":[155],"(10.1":[157],"9.3":[159],".183)":[163],"was":[164],"observed":[165],"between":[166],"histGB.":[169],"However,":[170],"demonstrated":[174],"improved":[175],"OS":[177],"(31.2":[178],"18":[180],"hazard":[182],"ratios":[183],"0.45).":[184],"distinguished":[188],"LGG,":[193,229],"achieving":[194],"a":[195],"best-performing":[196],"ROC":[197],"AUC":[198],"0.85.":[200],"CONCLUSIONS:":[201],"While":[202],"similar":[209],"survival,":[211],"appear":[217],"better":[220],"outcomes.":[221],"effectively":[225],"supporting":[230],"their":[231],"potential":[232],"diagnostic":[233],"utility.":[234]},"counts_by_year":[{"year":2026,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2025-10-10T00:00:00"}