{"id":"https://openalex.org/W4411368403","doi":"https://doi.org/10.2196/58204","title":"Evaluating a Mobile Digital Therapeutic for Vasomotor and Behavioral Health Symptoms Among Women in Midlife: Randomized Controlled Trial","display_name":"Evaluating a Mobile Digital Therapeutic for Vasomotor and Behavioral Health Symptoms Among Women in Midlife: Randomized Controlled Trial","publication_year":2025,"publication_date":"2025-06-17","ids":{"openalex":"https://openalex.org/W4411368403","doi":"https://doi.org/10.2196/58204","pmid":"https://pubmed.ncbi.nlm.nih.gov/40526898"},"language":"en","primary_location":{"id":"doi:10.2196/58204","doi":"https://doi.org/10.2196/58204","is_oa":true,"landing_page_url":"https://doi.org/10.2196/58204","pdf_url":"https://jmir.org/api/download?alt_name=mhealth_v13i1e58204_app1.pdf&filename=b91f37c1-4bb5-11f0-8172-7b8c76f76f3a.pdf","source":{"id":"https://openalex.org/S2764493120","display_name":"JMIR mhealth and uhealth","issn_l":"2291-5222","issn":["2291-5222"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320608","host_organization_name":"JMIR Publications","host_organization_lineage":["https://openalex.org/P4310320608"],"host_organization_lineage_names":["JMIR Publications"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JMIR mHealth and uHealth","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://jmir.org/api/download?alt_name=mhealth_v13i1e58204_app1.pdf&filename=b91f37c1-4bb5-11f0-8172-7b8c76f76f3a.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083918504","display_name":"Jennifer L. Duffecy","orcid":"https://orcid.org/0000-0002-4505-6820","observed_orcids":["https://orcid.org/0000-0002-4505-6820"]},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jennifer Duffecy","raw_affiliation_strings":["Department of Psychiatry, University of Illinois-Chicago, 912 S Wood, Chicago, IL, 60612, United States, 1 3124131225"],"raw_orcid":"https://orcid.org/0000-0002-4505-6820","affiliations":[{"raw_affiliation_string":"Department of Psychiatry, University of Illinois-Chicago, 912 S Wood, Chicago, IL, 60612, United States, 1 3124131225","institution_ids":["https://openalex.org/I39422238"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Arfa Rehman","orcid":"https://orcid.org/0009-0000-6340-5820","observed_orcids":["https://orcid.org/0009-0000-6340-5820"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Arfa Rehman","raw_affiliation_strings":["Chorus Health, San Francisco, CA, United States"],"raw_orcid":"https://orcid.org/0009-0000-6340-5820","affiliations":[{"raw_affiliation_string":"Chorus Health, San Francisco, CA, United States","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035847518","display_name":"Scott N. Gorman","orcid":"https://orcid.org/0009-0007-6572-8982","observed_orcids":["https://orcid.org/0009-0007-6572-8982"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Scott Gorman","raw_affiliation_strings":["Chorus Health, San Francisco, CA, United States"],"raw_orcid":"https://orcid.org/0009-0007-6572-8982","affiliations":[{"raw_affiliation_string":"Chorus Health, San Francisco, CA, United States","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029017504","display_name":"Yonglin Huang","orcid":"https://orcid.org/0000-0003-4186-7973","observed_orcids":["https://orcid.org/0000-0003-4186-7973"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yong Lin Huang","raw_affiliation_strings":["Chorus Health, San Francisco, CA, United States"],"raw_orcid":"https://orcid.org/0000-0003-4186-7973","affiliations":[{"raw_affiliation_string":"Chorus Health, San Francisco, CA, United States","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027645466","display_name":"Heide Klumpp","orcid":"https://orcid.org/0000-0003-2652-7479","observed_orcids":["https://orcid.org/0000-0003-2652-7479","https://orcid.org/0000-0003-3406-1373"]},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Heide Klumpp","raw_affiliation_strings":["Department of Psychiatry, University of Illinois-Chicago, 912 S Wood, Chicago, IL, 60612, United States, 1 3124131225"],"raw_orcid":"https://orcid.org/0000-0003-2652-7479","affiliations":[{"raw_affiliation_string":"Department of Psychiatry, University of Illinois-Chicago, 912 S Wood, Chicago, IL, 60612, United States, 1 3124131225","institution_ids":["https://openalex.org/I39422238"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2850,"currency":"USD","value_usd":2850},"apc_paid":{"value":2850,"currency":"USD","value_usd":2850},"fwci":12.4003,"has_fulltext":true,"cited_by_count":18,"citation_normalized_percentile":{"value":0.99014694,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"13","issue":null,"first_page":"e58204","last_page":"e58204"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.7734000086784363,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.7734000086784363,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11446","display_name":"Mobile Health and mHealth Applications","score":0.12300000339746475,"subfield":{"id":"https://openalex.org/subfields/3600","display_name":"General Health Professions"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11519","display_name":"Digital Mental Health Interventions","score":0.08810000121593475,"subfield":{"id":"https://openalex.org/subfields/3202","display_name":"Applied Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/menopause","display_name":"menopause","score":0.7580000162124634},{"id":"https://openalex.org/keywords/vasomotor-symptoms","display_name":"vasomotor symptoms","score":0.8939999938011169},{"id":"https://openalex.org/keywords/hot-flashes","display_name":"hot flashes","score":0.9700000286102295},{"id":"https://openalex.org/keywords/digital-therapeutics","display_name":"digital therapeutics","score":0.656000018119812},{"id":"https://openalex.org/keywords/mobile-health-apps","display_name":"mobile health apps","score":0.8790000081062317},{"id":"https://openalex.org/keywords/middle-aged-women","display_name":"middle-aged women","score":0.824999988079071},{"id":"https://openalex.org/keywords/perimenopause","display_name":"perimenopause","score":0.746999979019165},{"id":"https://openalex.org/keywords/depression","display_name":"depression","score":0.7860000133514404},{"id":"https://openalex.org/keywords/anxiety","display_name":"anxiety","score":0.9929999709129333},{"id":"https://openalex.org/keywords/sleep-quality","display_name":"sleep quality","score":0.8629999756813049},{"id":"https://openalex.org/keywords/behavioral-health","display_name":"behavioral health","score":0.6359999775886536},{"id":"https://openalex.org/keywords/self-management","display_name":"self-management","score":0.7120000123977661},{"id":"https://openalex.org/keywords/e-learning","display_name":"online learning","score":0.5040000081062317},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.6679999828338623},{"id":"https://openalex.org/keywords/smartphone-based-intervention","display_name":"smartphone-based intervention","score":0.37400001287460327},{"id":"https://openalex.org/keywords/web-based-intervention","display_name":"online intervention","score":0.32499998807907104},{"id":"https://openalex.org/keywords/anxiety-screening","display_name":"anxiety screening","score":0.7379999756813049}],"concepts":[{"id":"https://openalex.org/C2776128548","wikidata":"https://www.wikidata.org/wiki/Q1858291","display_name":"Hot flash","level":4,"score":0.8299174308776855},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7779759168624878},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.7041932940483093},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.5940564274787903},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.5828191637992859},{"id":"https://openalex.org/C2776245837","wikidata":"https://www.wikidata.org/wiki/Q25053505","display_name":"Pittsburgh Sleep Quality Index","level":4,"score":0.5812733769416809},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.5739582777023315},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.5304985046386719},{"id":"https://openalex.org/C2776214587","wikidata":"https://www.wikidata.org/wiki/Q3430227","display_name":"Vasomotor","level":2,"score":0.49891066551208496},{"id":"https://openalex.org/C102959455","wikidata":"https://www.wikidata.org/wiki/Q7313954","display_name":"Repeated measures design","level":2,"score":0.46242207288742065},{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.4560932219028473},{"id":"https://openalex.org/C2778562196","wikidata":"https://www.wikidata.org/wiki/Q177708","display_name":"Menopause","level":2,"score":0.4503442645072937},{"id":"https://openalex.org/C1513209611","wikidata":"https://www.wikidata.org/wiki/Q177190","display_name":"Sleep disorder","level":3,"score":0.4322054386138916},{"id":"https://openalex.org/C2778529449","wikidata":"https://www.wikidata.org/wiki/Q1778909","display_name":"Patient Health Questionnaire","level":4,"score":0.424521267414093},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.29717087745666504},{"id":"https://openalex.org/C2781210498","wikidata":"https://www.wikidata.org/wiki/Q1869874","display_name":"Insomnia","level":2,"score":0.2177402675151825},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.1559520661830902},{"id":"https://openalex.org/C3019858935","wikidata":"https://www.wikidata.org/wiki/Q4340209","display_name":"Depressive symptoms","level":3,"score":0.15529513359069824},{"id":"https://openalex.org/C2983189541","wikidata":"https://www.wikidata.org/wiki/Q35831","display_name":"Sleep quality","level":3,"score":0.14951041340827942},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.0},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011594","descriptor_name":"Psychometrics","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D011594","descriptor_name":"Psychometrics","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D011594","descriptor_name":"Psychometrics","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D011594","descriptor_name":"Psychometrics","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D011594","descriptor_name":"Psychometrics","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D011594","descriptor_name":"Psychometrics","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D011594","descriptor_name":"Psychometrics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D011594","descriptor_name":"Psychometrics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D011594","descriptor_name":"Psychometrics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D011594","descriptor_name":"Psychometrics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D011594","descriptor_name":"Psychometrics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D011594","descriptor_name":"Psychometrics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D011795","descriptor_name":"Surveys and Questionnaires","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011795","descriptor_name":"Surveys and Questionnaires","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011795","descriptor_name":"Surveys and Questionnaires","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011795","descriptor_name":"Surveys and Questionnaires","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011795","descriptor_name":"Surveys and Questionnaires","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011795","descriptor_name":"Surveys and Questionnaires","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019584","descriptor_name":"Hot Flashes","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D019584","descriptor_name":"Hot Flashes","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D019584","descriptor_name":"Hot Flashes","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D019584","descriptor_name":"Hot Flashes","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D019584","descriptor_name":"Hot Flashes","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D019584","descriptor_name":"Hot Flashes","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D019584","descriptor_name":"Hot Flashes","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D019584","descriptor_name":"Hot Flashes","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D019584","descriptor_name":"Hot Flashes","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D019584","descriptor_name":"Hot Flashes","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D019584","descriptor_name":"Hot Flashes","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D019584","descriptor_name":"Hot Flashes","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D057566","descriptor_name":"Self Report","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057566","descriptor_name":"Self Report","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057566","descriptor_name":"Self Report","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057566","descriptor_name":"Self Report","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057566","descriptor_name":"Self Report","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057566","descriptor_name":"Self Report","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063731","descriptor_name":"Mobile Applications","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D063731","descriptor_name":"Mobile Applications","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D063731","descriptor_name":"Mobile Applications","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D063731","descriptor_name":"Mobile Applications","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D063731","descriptor_name":"Mobile Applications","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D063731","descriptor_name":"Mobile Applications","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D063731","descriptor_name":"Mobile Applications","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D063731","descriptor_name":"Mobile Applications","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D063731","descriptor_name":"Mobile Applications","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D063731","descriptor_name":"Mobile Applications","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D063731","descriptor_name":"Mobile Applications","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D063731","descriptor_name":"Mobile Applications","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.2196/58204","doi":"https://doi.org/10.2196/58204","is_oa":true,"landing_page_url":"https://doi.org/10.2196/58204","pdf_url":"https://jmir.org/api/download?alt_name=mhealth_v13i1e58204_app1.pdf&filename=b91f37c1-4bb5-11f0-8172-7b8c76f76f3a.pdf","source":{"id":"https://openalex.org/S2764493120","display_name":"JMIR mhealth and uhealth","issn_l":"2291-5222","issn":["2291-5222"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320608","host_organization_name":"JMIR Publications","host_organization_lineage":["https://openalex.org/P4310320608"],"host_organization_lineage_names":["JMIR Publications"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JMIR mHealth and uHealth","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:10996692","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12187029","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:12187029","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12187029","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JMIR Mhealth Uhealth","raw_type":"Text"},{"id":"pmid:40526898","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40526898","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JMIR mHealth and uHealth","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:9f146caed80f4c889a65640d9a1e0222","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/9f146caed80f4c889a65640d9a1e0222","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"JMIR mHealth and uHealth, Vol 13, Pp e58204-e58204 (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.2196/58204","doi":"https://doi.org/10.2196/58204","is_oa":true,"landing_page_url":"https://doi.org/10.2196/58204","pdf_url":"https://jmir.org/api/download?alt_name=mhealth_v13i1e58204_app1.pdf&filename=b91f37c1-4bb5-11f0-8172-7b8c76f76f3a.pdf","source":{"id":"https://openalex.org/S2764493120","display_name":"JMIR mhealth and uhealth","issn_l":"2291-5222","issn":["2291-5222"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320608","host_organization_name":"JMIR Publications","host_organization_lineage":["https://openalex.org/P4310320608"],"host_organization_lineage_names":["JMIR Publications"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JMIR mHealth and uHealth","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.4399999976158142,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4411368403.pdf","grobid_xml":"https://content.openalex.org/works/W4411368403.grobid-xml"},"referenced_works_count":65,"referenced_works":["https://openalex.org/W1970433269","https://openalex.org/W1976780483","https://openalex.org/W2033442056","https://openalex.org/W2036735145","https://openalex.org/W2043705607","https://openalex.org/W2048533792","https://openalex.org/W2054796954","https://openalex.org/W2057065276","https://openalex.org/W2066930284","https://openalex.org/W2067747263","https://openalex.org/W2087484885","https://openalex.org/W2090700268","https://openalex.org/W2091326208","https://openalex.org/W2097412703","https://openalex.org/W2098637512","https://openalex.org/W2142144461","https://openalex.org/W2151487996","https://openalex.org/W2170641360","https://openalex.org/W2287296023","https://openalex.org/W2346722537","https://openalex.org/W2424128792","https://openalex.org/W2531988106","https://openalex.org/W2592214867","https://openalex.org/W2609940642","https://openalex.org/W2615609848","https://openalex.org/W2754358908","https://openalex.org/W2760160110","https://openalex.org/W2783219414","https://openalex.org/W2805811183","https://openalex.org/W2806049570","https://openalex.org/W2811268537","https://openalex.org/W2883137451","https://openalex.org/W2891829472","https://openalex.org/W2912016527","https://openalex.org/W2918103210","https://openalex.org/W2929051243","https://openalex.org/W2942118272","https://openalex.org/W2946923322","https://openalex.org/W2947521926","https://openalex.org/W2963232155","https://openalex.org/W2969667859","https://openalex.org/W2972598474","https://openalex.org/W2984965653","https://openalex.org/W2990241465","https://openalex.org/W3025959868","https://openalex.org/W3090010769","https://openalex.org/W3092464865","https://openalex.org/W3095063659","https://openalex.org/W3123322472","https://openalex.org/W3126058080","https://openalex.org/W3126826193","https://openalex.org/W3166153785","https://openalex.org/W4206246986","https://openalex.org/W4250980862","https://openalex.org/W4254396244","https://openalex.org/W4281714291","https://openalex.org/W4283835704","https://openalex.org/W4291017016","https://openalex.org/W4299911404","https://openalex.org/W4313133615","https://openalex.org/W4313311761","https://openalex.org/W4367056304","https://openalex.org/W4378744965","https://openalex.org/W4386175712","https://openalex.org/W4396561824"],"related_works":["https://openalex.org/W1980592568","https://openalex.org/W2009548737","https://openalex.org/W4230651747","https://openalex.org/W3169214165","https://openalex.org/W2090516774","https://openalex.org/W2007547790","https://openalex.org/W4244755943","https://openalex.org/W2094212531","https://openalex.org/W2885347398","https://openalex.org/W2368776154"],"abstract_inverted_index":{"Unlabelled:":[0],"Background:":[1],"Perimenopausal":[2],"and":[3,10,41,71,101,113,156,161,254,358,384,430],"menopausal":[4,22,382,422],"symptoms":[5,44,70,350,353],"affect":[6],"many":[7],"women's":[8],"well-being":[9],"quality":[11,264],"of":[12,45,220,298,377,403,408],"life.":[13],"Digital":[14],"technologies,":[15],"especially":[16],"smartphones,":[17],"allow":[18],"self-management":[19],"interventions":[20,379,419],"for":[21,52,152,380,428,433],"symptoms,":[23,423],"but":[24,228,306,336],"they":[25],"are":[26],"understudied.,":[27],"Objective:":[28],"We":[29,48],"evaluated":[30],"whether":[31],"a":[32,53,146,162,213,217,295,323,425],"novel":[33],"digital":[34,378,417],"care":[35],"app,":[36],"Caria,":[37],"effectively":[38],"reduced":[39],"vasomotor":[40,69,383],"behavioral":[42,76,385],"health":[43,77,386,418],"menopause.,":[46],"Methods:":[47],"enrolled":[49],"149":[50],"women":[51,434],"6-week":[54],"randomized":[55],"controlled":[56],"trial":[57],"(app":[58],"treatment:":[59],"n=112;":[60],"web-based":[61],"educational":[62],"control:":[63,134],"n=37).":[64],"Enrolled":[65],"participants":[66],"had":[67],"problematic":[68],"at":[72,109],"least":[73],"one":[74],"elevated":[75,348],"symptom":[78],"(depression,":[79],"anxiety,":[80],"or":[81],"sleep":[82,263,327],"issues).":[83],"Web-based":[84],"self-reported":[85],"assessments":[86],"(Hot":[87],"Flush":[88],"Rating":[89],"Scale":[90],"[HFRS],":[91],"Patient":[92],"Health":[93],"Questionnaire":[94],"Depression":[95],"Scale-8":[96],"[PHQ-8],":[97],"Generalized":[98],"Anxiety":[99],"Disorder-7,":[100],"Pittsburgh":[102],"Sleep":[103],"Quality":[104],"Index":[105],"[PSQI])":[106],"were":[107],"conducted":[108],"baseline,":[110],"3":[111,251,257,333,341],"weeks,":[112],"6":[114,259,343,368],"weeks.,":[115],"Results:":[116],"For":[117,185,262],"hot":[118,176],"flash":[119,177],"severity":[120,178],"(HFRS;":[121],"treatment":[122,157,166,172,189,224,242,267,302,320,357],"baseline":[123,135,190,202,248,268,280,330],"mean":[124,130,136,142,191,197,203,209,269,275,281,287],"16.4,":[125],"SD":[126,132,138,144,193,199,205,211,271,277,283,289],"6.7":[127],"to":[128,140,195,207,249,258,273,285,331,342,413],"6-wk":[129,141,196,208,274,286],"13.6,":[131],"6.6;":[133],"19.1,":[137],"7.3":[139],"17.8,":[143],"7.2),":[145],"repeated-measures":[147,214,292],"ANOVA":[148,215,293],"revealed":[149],"main":[150,218,296],"effects":[151],"time":[153,164,221,299],"(F2,262=9.82;":[154],"P<.001)":[155,227,335],"arm":[158,167,173,182,225,232,243,303,310,321],"(F1,131=6.08;":[159],"P=.01)":[160],"significant":[163,324],"\u00d7":[165],"interaction":[168],"(F2,262=3.23;":[169],"P=.04);":[170],"the":[171,180,223,230,241,291,301,308,319,356,375,391,395,404,414],"showed":[174,216,244,294,322,351],"lower":[175],"than":[179],"control":[181,201,231,279,309,359],"(t147=2.72;":[183],"P=.007).":[184],"depression":[186,245],"scores":[187,265],"(PHQ-8;":[188],"14.0,":[192],"3.8":[194],"11.2,":[198],"5.3;":[200],"15.0,":[204],"3.7":[206,284],"13.4,":[210],"4.1),":[212],"effect":[219,297],"in":[222,240,300,318,326,354,390,398,420,435],"(F2,96=15.2;":[226],"not":[229,307],"(F2,40=2.0;":[233],"P=.15).":[234],"Follow-up":[235,313],"2-tailed":[236,314],"paired":[237,315],"t":[238,316],"tests":[239,317],"decreased":[246,352],"from":[247,255,329,339,401],"week":[250,332],"(t49=3.3;":[252],"P=.002)":[253],"weeks":[256,340],"(t48=2.3;":[260],"P=.02).":[261],"(PSQI;":[266],"10.7,":[270],"3.1":[272],"10.0,":[276],"3.5;":[278],"11.5,":[282],"11.0,":[288],"3.7),":[290],"(F2,186=7.8;":[304],"P=.001)":[305],"(F2,62=1.3;":[311],"P=.28).":[312],"decrease":[325],"issues":[328],"(t95=3.9;":[334],"no":[337],"change":[338],"(t93=0.2;":[344],"P=.81).":[345],"Participants":[346],"with":[347],"anxiety":[349],"both":[355],"groups.":[360],"App":[361],"engagement":[362],"was":[363],"high":[364],"(average":[365],"logins":[366],"over":[367],"weeks:":[369],"53.2).,":[370],"Conclusions:":[371],"The":[372],"findings":[373],"highlight":[374],"potential":[376],"mitigating":[381],"symptoms.":[387],"Significant":[388],"improvements":[389],"intervention":[392],"group":[393],"underscore":[394],"app's":[396],"effectiveness":[397],"providing":[399],"relief":[400],"some":[402],"most":[405],"challenging":[406],"aspects":[407],"menopause.":[409],"This":[410],"study":[411],"contributes":[412],"evidence":[415],"supporting":[416],"managing":[421],"presenting":[424],"promising":[426],"avenue":[427],"accessible":[429],"scalable":[431],"solutions":[432],"midlife.":[436]},"counts_by_year":[{"year":2026,"cited_by_count":16},{"year":2025,"cited_by_count":2}],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2025-10-10T00:00:00"}