{"id":"https://openalex.org/W4411286744","doi":"https://doi.org/10.1142/s2737416525300019","title":"Unraveling Genetic Markers in Breast Cancer: Bioinformatics Perspectives","display_name":"Unraveling Genetic Markers in Breast Cancer: Bioinformatics Perspectives","publication_year":2025,"publication_date":"2025-06-13","ids":{"openalex":"https://openalex.org/W4411286744","doi":"https://doi.org/10.1142/s2737416525300019"},"language":"en","primary_location":{"id":"doi:10.1142/s2737416525300019","doi":"https://doi.org/10.1142/s2737416525300019","is_oa":false,"landing_page_url":"https://doi.org/10.1142/s2737416525300019","pdf_url":null,"source":{"id":"https://openalex.org/S4210170239","display_name":"Journal of Computational Biophysics and Chemistry","issn_l":"2737-4165","issn":["2737-4165","2737-4173"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","norway-1","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319815","host_organization_name":"World Scientific","host_organization_lineage":["https://openalex.org/P4310319815"],"host_organization_lineage_names":["World Scientific"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Computational Biophysics and Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101736187","display_name":"Ahmed Faisal","orcid":"https://orcid.org/0009-0005-5992-0041","observed_orcids":["https://orcid.org/0009-0005-5992-0041","https://orcid.org/0009-0002-5124-9730"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Ahmed Faisal Mutee","raw_affiliation_strings":["College of Pharmacy, Alnoor University, Mosul, Iraq"],"raw_orcid":"https://orcid.org/0009-0002-5124-9730","affiliations":[{"raw_affiliation_string":"College of Pharmacy, Alnoor University, Mosul, Iraq","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111053009","display_name":"Abdulkareem Shareef","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2955852263","display_name":"Ahl Al Bayt University","ror":"https://ror.org/01h3hm524","country_code":"IQ","type":"education","lineage":["https://openalex.org/I2955852263"]}],"countries":["IQ"],"is_corresponding":false,"raw_author_name":"Abdulkareem Shareef","raw_affiliation_strings":["Ahl Al Bayt University, Kerbala, Iraq"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ahl Al Bayt University, Kerbala, Iraq","institution_ids":["https://openalex.org/I2955852263"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092191519","display_name":"S RenukaJyothi","orcid":"https://orcid.org/0000-0003-3248-337X","observed_orcids":["https://orcid.org/0000-0003-3248-337X"]},"institutions":[{"id":"https://openalex.org/I106826634","display_name":"Jain University","ror":"https://ror.org/01cnqpt53","country_code":"IN","type":"education","lineage":["https://openalex.org/I106826634"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"S. RenukaJyothi","raw_affiliation_strings":["Department of Biotechnology and Genetics, School of Sciences, JAIN (Deemed to be University), Bangalore, Karnataka, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology and Genetics, School of Sciences, JAIN (Deemed to be University), Bangalore, Karnataka, India","institution_ids":["https://openalex.org/I106826634"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040483637","display_name":"Rajashree Panigrahi","orcid":"https://orcid.org/0009-0009-8606-3961","observed_orcids":["https://orcid.org/0009-0009-8606-3961"]},"institutions":[{"id":"https://openalex.org/I193073490","display_name":"Siksha O Anusandhan University","ror":"https://ror.org/056ep7w45","country_code":"IN","type":"education","lineage":["https://openalex.org/I193073490"]},{"id":"https://openalex.org/I4210133319","display_name":"Institute of Medical Sciences and Sum Hospital","ror":"https://ror.org/03ht2bz32","country_code":"IN","type":"education","lineage":["https://openalex.org/I4210133319"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Rajashree Panigrahi","raw_affiliation_strings":["Department of Microbiology, IMS and SUM Hospital, Siksha \u2018O\u2019 Anusandhan (Deemed to be University), Bhubaneswar 751003, Odisha, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, IMS and SUM Hospital, Siksha \u2018O\u2019 Anusandhan (Deemed to be University), Bhubaneswar 751003, Odisha, India","institution_ids":["https://openalex.org/I193073490","https://openalex.org/I4210133319"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050812296","display_name":"Vikrant Abbot","orcid":"https://orcid.org/0000-0003-3715-3329","observed_orcids":["https://orcid.org/0000-0003-3715-3329"]},"institutions":[{"id":"https://openalex.org/I1281160679","display_name":"Graphic Era Hill University","ror":"https://ror.org/01bb4h160","country_code":"IN","type":"education","lineage":["https://openalex.org/I1281160679"]},{"id":"https://openalex.org/I60054993","display_name":"Graphic Era University","ror":"https://ror.org/03wqgqd89","country_code":"IN","type":"education","lineage":["https://openalex.org/I60054993"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Vikrant Abbot","raw_affiliation_strings":["Centre for Promotion of Research, Graphic Era Deemed to be University, Dehradun 248002, Uttarakhand, India","Department of Pharmacy, Graphic Era Hill University, Dehradun, India"],"raw_orcid":"https://orcid.org/0000-0003-3715-3329","affiliations":[{"raw_affiliation_string":"Centre for Promotion of Research, Graphic Era Deemed to be University, Dehradun 248002, Uttarakhand, India","institution_ids":["https://openalex.org/I60054993"]},{"raw_affiliation_string":"Department of Pharmacy, Graphic Era Hill University, Dehradun, India","institution_ids":["https://openalex.org/I1281160679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032073074","display_name":"Ashish Singh Chauhan","orcid":"https://orcid.org/0009-0004-7154-2584","observed_orcids":["https://orcid.org/0009-0004-7154-2584"]},"institutions":[{"id":"https://openalex.org/I3132702812","display_name":"Uttaranchal University","ror":"https://ror.org/00ba6pg24","country_code":"IN","type":"education","lineage":["https://openalex.org/I3132702812"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Ashish Singh Chauhan","raw_affiliation_strings":["Uttaranchal Institute of Pharmaceutical Sciences, Division of Research and Innovation, Uttaranchal University, Dehradun, Uttarakhand, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Uttaranchal Institute of Pharmaceutical Sciences, Division of Research and Innovation, Uttaranchal University, Dehradun, Uttarakhand, India","institution_ids":["https://openalex.org/I3132702812"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Surbhi Singh","orcid":"https://orcid.org/0000-0001-7309-6777","observed_orcids":["https://orcid.org/0000-0001-7309-6777"]},"institutions":[{"id":"https://openalex.org/I74319210","display_name":"Chitkara University","ror":"https://ror.org/057d6z539","country_code":"IN","type":"education","lineage":["https://openalex.org/I74319210"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Surbhi Singh","raw_affiliation_strings":["Centre for Research Impact & Outcome, Chitkara University Institute of Engineering and Technology, Chitkara University, Rajpura 140401, Punjab, India"],"raw_orcid":"https://orcid.org/0000-0001-7309-6777","affiliations":[{"raw_affiliation_string":"Centre for Research Impact & Outcome, Chitkara University Institute of Engineering and Technology, Chitkara University, Rajpura 140401, Punjab, India","institution_ids":["https://openalex.org/I74319210"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058533758","display_name":"Djamila Polatova","orcid":"https://orcid.org/0000-0001-8128-2553","observed_orcids":["https://orcid.org/0000-0001-8128-2553"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Djamila Polatova","raw_affiliation_strings":["Scientific-Practical Medical Center for Pediatric Oncology, Hematology and Immunology, Tashkent, Uzbekistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Scientific-Practical Medical Center for Pediatric Oncology, Hematology and Immunology, Tashkent, Uzbekistan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114388965","display_name":"Hayder Naji Sameer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405254421","display_name":"National University of Science and Technology","ror":"https://ror.org/01ss3xk05","country_code":"IQ","type":"education","lineage":["https://openalex.org/I4405254421"]}],"countries":["IQ"],"is_corresponding":false,"raw_author_name":"Hayder Naji Sameer","raw_affiliation_strings":["Collage of Pharmacy, National University of Science and Technology, Dhi Qar 64001, Iraq"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Collage of Pharmacy, National University of Science and Technology, Dhi Qar 64001, Iraq","institution_ids":["https://openalex.org/I4405254421"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Ahmed Yaseen","orcid":"https://orcid.org/0000-0002-1471-4800","observed_orcids":["https://orcid.org/0000-0002-1471-4800"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ahmed Yaseen","raw_affiliation_strings":["Gilgamesh Ahliya University, Baghdad, Iraq"],"raw_orcid":"https://orcid.org/0000-0002-1471-4800","affiliations":[{"raw_affiliation_string":"Gilgamesh Ahliya University, Baghdad, Iraq","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093850410","display_name":"Zainab H. Athab","orcid":"https://orcid.org/0009-0007-3736-5205","observed_orcids":["https://orcid.org/0009-0007-3736-5205"]},"institutions":[{"id":"https://openalex.org/I4405253933","display_name":"Al-Zahrawi University","ror":"https://ror.org/017jj3e32","country_code":"IQ","type":"education","lineage":["https://openalex.org/I4405253933"]}],"countries":["IQ"],"is_corresponding":false,"raw_author_name":"Zainab H. Athab","raw_affiliation_strings":["Department of Pharmacy, Al-Zahrawi University College, Karbala, Iraq"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, Al-Zahrawi University College, Karbala, Iraq","institution_ids":["https://openalex.org/I4405253933"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065673357","display_name":"Mohaned Adil","orcid":"https://orcid.org/0009-0000-9607-0684","observed_orcids":["https://orcid.org/0009-0000-9607-0684"]},"institutions":[{"id":"https://openalex.org/I4401200352","display_name":"Al-Farahidi University","ror":"https://ror.org/0409yxb12","country_code":"IQ","type":"education","lineage":["https://openalex.org/I4401200352"]}],"countries":["IQ"],"is_corresponding":false,"raw_author_name":"Mohaned Adil","raw_affiliation_strings":["Pharmacy College, Al-Farahidi University, Baghdad, Iraq"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pharmacy College, Al-Farahidi University, Baghdad, Iraq","institution_ids":["https://openalex.org/I4401200352"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5101736187"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.12672811,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"25","issue":"08","first_page":"1093","last_page":"1118"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.76419997215271,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.76419997215271,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.17599999904632568,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.03959999978542328,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.9990000128746033},{"id":"https://openalex.org/keywords/genetic-markers","display_name":"genetic markers","score":0.8870000243186951},{"id":"https://openalex.org/keywords/biomarker-discovery","display_name":"biomarker discovery","score":0.5899999737739563},{"id":"https://openalex.org/keywords/transcriptomics","display_name":"transcriptomics","score":0.6909999847412109},{"id":"https://openalex.org/keywords/differentially-expressed-genes","display_name":"differentially expressed genes","score":0.9409999847412109},{"id":"https://openalex.org/keywords/hub-genes","display_name":"hub genes","score":0.9890000224113464},{"id":"https://openalex.org/keywords/protein-protein-interaction-network","display_name":"protein-protein interaction network","score":0.9259999990463257},{"id":"https://openalex.org/keywords/breast-cancer-subtypes","display_name":"breast cancer subtypes","score":0.7210000157356262},{"id":"https://openalex.org/keywords/precision-oncology","display_name":"precision oncology","score":0.7179999947547913},{"id":"https://openalex.org/keywords/parp-inhibitors","display_name":"PARP inhibitors","score":0.8569999933242798},{"id":"https://openalex.org/keywords/trastuzumab","display_name":"trastuzumab","score":0.9980000257492065},{"id":"https://openalex.org/keywords/liquid-biopsy","display_name":"liquid biopsy","score":0.9950000047683716},{"id":"https://openalex.org/keywords/single-cell-multi-omics","display_name":"single-cell multi-omics","score":0.9929999709129333},{"id":"https://openalex.org/keywords/tumor-heterogeneity","display_name":"tumor heterogeneity","score":0.8309999704360962},{"id":"https://openalex.org/keywords/dataset-bias","display_name":"data bias","score":0.5419999957084656},{"id":"https://openalex.org/keywords/survival-analysis","display_name":"survival analysis","score":0.49799999594688416}],"concepts":[{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.6292049884796143},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.512665867805481},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.404910683631897},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3749431371688843},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3573969006538391},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3545297384262085},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2970609664916992}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1142/s2737416525300019","doi":"https://doi.org/10.1142/s2737416525300019","is_oa":false,"landing_page_url":"https://doi.org/10.1142/s2737416525300019","pdf_url":null,"source":{"id":"https://openalex.org/S4210170239","display_name":"Journal of Computational Biophysics and Chemistry","issn_l":"2737-4165","issn":["2737-4165","2737-4173"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","norway-1","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319815","host_organization_name":"World Scientific","host_organization_lineage":["https://openalex.org/P4310319815"],"host_organization_lineage_names":["World Scientific"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Computational Biophysics and Chemistry","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"},{"score":0.7390999794006348,"id":"https://metadata.un.org/sdg/10","display_name":"Reduced inequalities"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":159,"referenced_works":["https://openalex.org/W92469554","https://openalex.org/W1757990252","https://openalex.org/W1792532087","https://openalex.org/W1917647701","https://openalex.org/W1964321121","https://openalex.org/W1966327575","https://openalex.org/W1971937094","https://openalex.org/W1973569665","https://openalex.org/W1977267072","https://openalex.org/W1977556410","https://openalex.org/W1998767819","https://openalex.org/W2004292826","https://openalex.org/W2005895632","https://openalex.org/W2017558877","https://openalex.org/W2023316892","https://openalex.org/W2030301791","https://openalex.org/W2030638637","https://openalex.org/W2032518018","https://openalex.org/W2033341544","https://openalex.org/W2036913140","https://openalex.org/W2045949302","https://openalex.org/W2062071674","https://openalex.org/W2070050178","https://openalex.org/W2076513103","https://openalex.org/W2083543572","https://openalex.org/W2085934079","https://openalex.org/W2089319616","https://openalex.org/W2103017472","https://openalex.org/W2103912979","https://openalex.org/W2105882193","https://openalex.org/W2106036365","https://openalex.org/W2107665951","https://openalex.org/W2108713158","https://openalex.org/W2114104545","https://openalex.org/W2116634113","https://openalex.org/W2128985829","https://openalex.org/W2129769331","https://openalex.org/W2130410032","https://openalex.org/W2131271579","https://openalex.org/W2132022337","https://openalex.org/W2132619562","https://openalex.org/W2134967712","https://openalex.org/W2135046866","https://openalex.org/W2136737404","https://openalex.org/W2136850043","https://openalex.org/W2140575188","https://openalex.org/W2146512944","https://openalex.org/W2154897810","https://openalex.org/W2156323704","https://openalex.org/W2158485828","https://openalex.org/W2159675211","https://openalex.org/W2163296115","https://openalex.org/W2163480486","https://openalex.org/W2167198989","https://openalex.org/W2169456326","https://openalex.org/W2170989872","https://openalex.org/W2179438025","https://openalex.org/W2187985754","https://openalex.org/W2190545194","https://openalex.org/W2214665719","https://openalex.org/W2233603983","https://openalex.org/W2318605753","https://openalex.org/W2406250479","https://openalex.org/W2461427403","https://openalex.org/W2471536144","https://openalex.org/W2475362987","https://openalex.org/W2518696212","https://openalex.org/W2552099557","https://openalex.org/W2608202513","https://openalex.org/W2612467560","https://openalex.org/W2620721366","https://openalex.org/W2621271973","https://openalex.org/W2735272571","https://openalex.org/W2735699461","https://openalex.org/W2736730167","https://openalex.org/W2769635882","https://openalex.org/W2782454362","https://openalex.org/W2786031287","https://openalex.org/W2788302995","https://openalex.org/W2794480084","https://openalex.org/W2794521141","https://openalex.org/W2795051895","https://openalex.org/W2800392236","https://openalex.org/W2803520432","https://openalex.org/W2810311882","https://openalex.org/W2811091623","https://openalex.org/W2822732030","https://openalex.org/W2887014156","https://openalex.org/W2889213939","https://openalex.org/W2895380444","https://openalex.org/W2896264577","https://openalex.org/W2900569176","https://openalex.org/W2905726353","https://openalex.org/W2908059055","https://openalex.org/W2908755714","https://openalex.org/W2921797260","https://openalex.org/W2938101988","https://openalex.org/W2942698526","https://openalex.org/W2946657092","https://openalex.org/W2949986034","https://openalex.org/W2954020426","https://openalex.org/W2969843874","https://openalex.org/W2972650179","https://openalex.org/W2974900542","https://openalex.org/W2981719747","https://openalex.org/W2987032426","https://openalex.org/W2991157178","https://openalex.org/W2992324722","https://openalex.org/W2995268793","https://openalex.org/W3012440210","https://openalex.org/W3027453227","https://openalex.org/W3043793790","https://openalex.org/W3044605555","https://openalex.org/W3092849554","https://openalex.org/W3093053585","https://openalex.org/W3102147110","https://openalex.org/W3107527779","https://openalex.org/W3122882833","https://openalex.org/W3128646645","https://openalex.org/W3145969289","https://openalex.org/W3147894994","https://openalex.org/W3164332865","https://openalex.org/W3164692211","https://openalex.org/W3177828909","https://openalex.org/W3203777534","https://openalex.org/W3207670652","https://openalex.org/W3210575985","https://openalex.org/W4206700689","https://openalex.org/W4206965224","https://openalex.org/W4214911184","https://openalex.org/W4220831425","https://openalex.org/W4224942755","https://openalex.org/W4229446553","https://openalex.org/W4242743062","https://openalex.org/W4289536142","https://openalex.org/W4289950901","https://openalex.org/W4294107304","https://openalex.org/W4294189863","https://openalex.org/W4301159569","https://openalex.org/W4303621840","https://openalex.org/W4306768310","https://openalex.org/W4307328165","https://openalex.org/W4315754639","https://openalex.org/W4321500249","https://openalex.org/W4361276321","https://openalex.org/W4389040545","https://openalex.org/W4389992195","https://openalex.org/W4392756650","https://openalex.org/W4393935425","https://openalex.org/W4396229173","https://openalex.org/W4398151996","https://openalex.org/W4398316468","https://openalex.org/W4402673179","https://openalex.org/W4403897697","https://openalex.org/W4404436738","https://openalex.org/W4404536322","https://openalex.org/W4408498562","https://openalex.org/W4408690953","https://openalex.org/W4410264223"],"related_works":["https://openalex.org/W4414756797","https://openalex.org/W4412392637","https://openalex.org/W7131069385","https://openalex.org/W4416412042","https://openalex.org/W7220052196","https://openalex.org/W4408399707","https://openalex.org/W4295077828","https://openalex.org/W4412984257","https://openalex.org/W4413273379","https://openalex.org/W4281705810"],"abstract_inverted_index":{"Breast":[0],"cancer,":[1,44],"the":[2,19,159,203],"most":[3],"prevalent":[4],"malignancy":[5],"in":[6,42,154],"women":[7],"globally,":[8],"is":[9],"a":[10,198],"formidable":[11],"challenge":[12],"due":[13],"to":[14,38,118,201],"its":[15],"molecular":[16,192],"heterogeneity":[17,142],"and":[18,29,55,65,78,80,89,103,112,125,133,143,158,176,194],"disparate":[20],"clinical":[21,195],"outcomes":[22],"of":[23,162],"luminal":[24,26],"A,":[25],"B,":[27],"HER2-enriched":[28],"triple-negative":[30],"subtypes.":[31],"The":[32],"current":[33],"review":[34],"integrates":[35],"bioinformatics":[36,189],"approaches":[37],"decipher":[39],"genetic":[40],"markers":[41],"breast":[43,205],"focusing":[45],"on":[46],"transcriptomics-based":[47],"pipelines":[48,68],"for":[49,93,108,167,182],"discovering":[50],"differentially":[51],"expressed":[52],"genes":[53],"(DEGs)":[54],"key":[56],"hub":[57],"genes.":[58],"Leveraging":[59],"datasets":[60,175],"from":[61],"databases":[62],"like":[63],"TCGA":[64],"GEO,":[66],"these":[67],"cover":[69],"data":[70],"acquisition,":[71],"preprocessing":[72],"with":[73,115,179],"packages":[74],"such":[75,121,129,151],"as":[76,122,130,152],"DESeq2":[77],"Scanpy,":[79],"advanced":[81],"analyses":[82],"including":[83],"functional":[84],"enrichment,":[85],"protein\u2013protein":[86],"interaction":[87],"network":[88],"machine":[90],"learning":[91],"algorithms":[92],"biomarker":[94],"prioritization.":[95],"Clinically":[96],"relevant":[97],"markers,":[98],"validated":[99],"through":[100],"survival":[101],"analysis":[102],"experimental":[104],"validation,":[105],"are":[106],"used":[107],"informing":[109],"diagnosis,":[110],"prognosis":[111],"treatment":[113],"strategies,":[114],"special":[116],"reference":[117],"precision":[119,138,185],"therapies":[120],"PARP":[123],"inhibitors":[124],"trastuzumab.":[126],"Emerging":[127],"technologies,":[128],"liquid":[131],"biopsy":[132],"single-cell":[134],"multi-omics,":[135],"enhance":[136],"diagnostic":[137],"by":[139],"alleviating":[140],"tumor":[141],"enabling":[144],"noninvasive":[145],"monitoring.":[146],"However,":[147],"unresolved":[148],"issues":[149],"persist,":[150],"disparities":[153],"healthcare,":[155],"dataset":[156],"biases":[157],"high":[160],"cost":[161],"genomic":[163],"profiling.":[164],"Future":[165],"directions":[166],"development":[168],"include":[169],"developing":[170],"cost-effective":[171],"tools,":[172],"enhancing":[173],"diverse":[174],"integrating":[177],"multi-omics":[178],"artificial":[180],"intelligence":[181],"advancing":[183],"equitable":[184],"oncology.":[186],"This":[187],"comprehensive":[188],"pipeline":[190],"bridges":[191],"findings":[193],"relevance,":[196],"offering":[197],"promising":[199],"strategy":[200],"alleviate":[202],"global":[204],"cancer":[206],"burden.":[207]},"counts_by_year":[],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2025-10-10T00:00:00"}