{"id":"https://openalex.org/W4411285246","doi":"https://doi.org/10.1158/1078-0432.29313458","title":"Supplementary Table S4 from Safety and Efficacy of KN046 in Combination with KN026 in Patients with Advanced HER2-Positive Breast Cancer: A Phase II Trial","display_name":"Supplementary Table S4 from Safety and Efficacy of KN046 in Combination with KN026 in Patients with Advanced HER2-Positive Breast Cancer: A Phase II Trial","publication_year":2025,"publication_date":"2025-06-13","ids":{"openalex":"https://openalex.org/W4411285246","doi":"https://doi.org/10.1158/1078-0432.29313458"},"language":"en","primary_location":{"id":"doi:10.1158/1078-0432.29313458","doi":"https://doi.org/10.1158/1078-0432.29313458","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.29313458","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/1078-0432.29313458","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100772480","display_name":"Jieqiong Liu","orcid":"https://orcid.org/0000-0001-7859-3764","observed_orcids":["https://orcid.org/0000-0001-7859-3764"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jieqiong Liu","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7859-3764","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036547986","display_name":"Chengyang Song","orcid":"https://orcid.org/0009-0008-0749-568X","observed_orcids":["https://orcid.org/0009-0008-0749-568X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chuangui Song","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0008-0749-568X","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013478611","display_name":"Yaping Yang","orcid":"https://orcid.org/0000-0001-7158-8807","observed_orcids":["https://orcid.org/0000-0001-7158-8807"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yaping Yang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7158-8807","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085661325","display_name":"Xiangcai Wang","orcid":"https://orcid.org/0000-0002-7162-0552","observed_orcids":["https://orcid.org/0000-0002-7162-0552"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xiangcai Wang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-7162-0552","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109406653","display_name":"Mingli Ni","orcid":"https://orcid.org/0009-0009-9972-3754","observed_orcids":["https://orcid.org/0009-0009-9972-3754","https://orcid.org/0009-0006-3631-5110"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mingli Ni","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0009-9972-3754","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058934381","display_name":"Xujuan Wang","orcid":"https://orcid.org/0009-0003-9145-7902","observed_orcids":["https://orcid.org/0009-0003-9145-7902"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xujuan Wang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0003-9145-7902","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100333502","display_name":"Lei Chen","orcid":"https://orcid.org/0009-0008-0975-1464","observed_orcids":["https://orcid.org/0009-0008-0975-1464"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lei Chen","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0008-0975-1464","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073289796","display_name":"Hongwei Yang","orcid":"https://orcid.org/0009-0006-8788-3230","observed_orcids":["https://orcid.org/0009-0006-8788-3230"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hongwei Yang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0006-8788-3230","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031486647","display_name":"Rusen Zhao","orcid":"https://orcid.org/0009-0009-2151-0863","observed_orcids":["https://orcid.org/0009-0009-2151-0863"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rusen Zhao","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0009-2151-0863","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111109696","display_name":"Ting Xu","orcid":"https://orcid.org/0000-0002-0172-9683","observed_orcids":["https://orcid.org/0000-0002-0172-9683"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ting Xu","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-0172-9683","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5073838859","display_name":"Lin Shen","orcid":"https://orcid.org/0000-0002-8798-4756","observed_orcids":["https://orcid.org/0000-0002-8798-4756","https://orcid.org/0000-0003-1134-2922"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lin Shen","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-8798-4756","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10755","display_name":"HER2/EGFR in Cancer Research","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10755","display_name":"HER2/EGFR in Cancer Research","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.002899999963119626,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10417","display_name":"Lung Cancer Treatments and Mutations","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/her2-positive-breast-cancer","display_name":"HER2-positive breast cancer","score":0.8679999709129333},{"id":"https://openalex.org/keywords/immune-related-adverse-events","display_name":"immune-related adverse events","score":0.9089999794960022},{"id":"https://openalex.org/keywords/immune-checkpoint-inhibitors","display_name":"immune checkpoint inhibitors","score":0.6840000152587891},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.6489999890327454},{"id":"https://openalex.org/keywords/advanced-breast-cancer","display_name":"advanced breast cancer","score":0.656000018119812}],"concepts":[{"id":"https://openalex.org/C45235069","wikidata":"https://www.wikidata.org/wiki/Q278425","display_name":"Table (database)","level":2,"score":0.7040915489196777},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.6533536911010742},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.6366050839424133},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5811226963996887},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5599431991577148},{"id":"https://openalex.org/C44280652","wikidata":"https://www.wikidata.org/wiki/Q104837","display_name":"Phase (matter)","level":2,"score":0.44694918394088745},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.39515310525894165},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.1511515974998474},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.12283894419670105},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.06809988617897034},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1158/1078-0432.29313458","doi":"https://doi.org/10.1158/1078-0432.29313458","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.29313458","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/29313458","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Supplementary_Table_S4_from_Safety_and_Efficacy_of_KN046_in_Combination_with_KN026_in_Patients_with_Advanced_HER2-Positive_Breast_Cancer_A_Phase_II_Trial/29313458","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1158/1078-0432.29313458","doi":"https://doi.org/10.1158/1078-0432.29313458","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.29313458","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4409160227","https://openalex.org/W4411285776","https://openalex.org/W4408588786","https://openalex.org/W3099291860","https://openalex.org/W4282969316","https://openalex.org/W4379282390","https://openalex.org/W3181374137","https://openalex.org/W4221041750","https://openalex.org/W3203083241","https://openalex.org/W4322771093"],"abstract_inverted_index":{"Supplemental":[0],"table":[1],"4":[2],"Immune-related":[3],"adverse":[4],"events":[5],"(irAEs)":[6],"in":[7],"patients":[8]},"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2025-10-10T00:00:00"}