{"id":"https://openalex.org/W4411274226","doi":"https://doi.org/10.1016/j.jbc.2025.110082","title":"Abstract 1334 Structural Insights Into G Protein-Coupled Receptor Kinase 5 Phosphorylation of Neurotensin Receptor 1","display_name":"Abstract 1334 Structural Insights Into G Protein-Coupled Receptor Kinase 5 Phosphorylation of Neurotensin Receptor 1","publication_year":2025,"publication_date":"2025-05-01","ids":{"openalex":"https://openalex.org/W4411274226","doi":"https://doi.org/10.1016/j.jbc.2025.110082"},"language":"en","primary_location":{"id":"doi:10.1016/j.jbc.2025.110082","doi":"https://doi.org/10.1016/j.jbc.2025.110082","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jbc.2025.110082","pdf_url":"https://www.jbc.org/action/showPdf?pii=S0021925825019313","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.jbc.org/action/showPdf?pii=S0021925825019313","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101774245","display_name":"Jiaqi Xiao","orcid":"https://orcid.org/0000-0002-3253-9591","observed_orcids":["https://orcid.org/0000-0002-3253-9591"]},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jiaqi Xiao","raw_affiliation_strings":["Purdue University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Purdue University","institution_ids":["https://openalex.org/I219193219"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037144273","display_name":"John J. G. Tesmer","orcid":"https://orcid.org/0000-0003-1125-3727","observed_orcids":["https://orcid.org/0000-0003-1125-3727"]},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John Tesmer","raw_affiliation_strings":["Purdue University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Purdue University","institution_ids":["https://openalex.org/I219193219"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043435719","display_name":"Qiuyan Chen","orcid":"https://orcid.org/0000-0002-6263-6843","observed_orcids":["https://orcid.org/0000-0002-6263-6843","https://orcid.org/0000-0001-9637-4995"]},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Qiuyan Chen","raw_affiliation_strings":["Purdue University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Purdue University","institution_ids":["https://openalex.org/I219193219"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I219193219"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":3430,"currency":"USD","value_usd":3430},"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"301","issue":"5","first_page":"110082","last_page":"110082"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/grk5","display_name":"GRK5","score":0.9810000061988831},{"id":"https://openalex.org/keywords/neurotensin-receptor-1","display_name":"neurotensin receptor 1","score":0.984000027179718},{"id":"https://openalex.org/keywords/receptor-phosphorylation","display_name":"receptor phosphorylation","score":0.8949999809265137},{"id":"https://openalex.org/keywords/receptor-desensitization","display_name":"receptor desensitization","score":0.6650000214576721}],"concepts":[{"id":"https://openalex.org/C2778976297","wikidata":"https://www.wikidata.org/wiki/Q419576","display_name":"Neurotensin","level":4,"score":0.63702392578125},{"id":"https://openalex.org/C2777307743","wikidata":"https://www.wikidata.org/wiki/Q24782815","display_name":"Neurotensin receptor","level":5,"score":0.6229972839355469},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.5181537866592407},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.4845942258834839},{"id":"https://openalex.org/C135285700","wikidata":"https://www.wikidata.org/wiki/Q38173","display_name":"G protein-coupled receptor","level":3,"score":0.46489375829696655},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.44801801443099976},{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.4164777100086212},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.40360796451568604},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.39723262190818787},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31358110904693604},{"id":"https://openalex.org/C118303440","wikidata":"https://www.wikidata.org/wiki/Q419968","display_name":"Neuropeptide","level":3,"score":0.0853358805179596}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jbc.2025.110082","doi":"https://doi.org/10.1016/j.jbc.2025.110082","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jbc.2025.110082","pdf_url":"https://www.jbc.org/action/showPdf?pii=S0021925825019313","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.jbc.2025.110082","doi":"https://doi.org/10.1016/j.jbc.2025.110082","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jbc.2025.110082","pdf_url":"https://www.jbc.org/action/showPdf?pii=S0021925825019313","source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4411274226.pdf","grobid_xml":"https://content.openalex.org/works/W4411274226.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4237594065","https://openalex.org/W7099113631","https://openalex.org/W2016352601","https://openalex.org/W4396849833","https://openalex.org/W1245933497","https://openalex.org/W2575696687","https://openalex.org/W7161849166","https://openalex.org/W7095560067","https://openalex.org/W2167732765","https://openalex.org/W2081346925"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}