{"id":"https://openalex.org/W4411200577","doi":"https://doi.org/10.1016/j.jogc.2025.102847","title":"Safety and Tolerability of E4/DRSP in Post-menarchal Female Adolescents","display_name":"Safety and Tolerability of E4/DRSP in Post-menarchal Female Adolescents","publication_year":2025,"publication_date":"2025-06-01","ids":{"openalex":"https://openalex.org/W4411200577","doi":"https://doi.org/10.1016/j.jogc.2025.102847"},"language":"en","primary_location":{"id":"doi:10.1016/j.jogc.2025.102847","doi":"https://doi.org/10.1016/j.jogc.2025.102847","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jogc.2025.102847","pdf_url":null,"source":{"id":"https://openalex.org/S2755151586","display_name":"Journal of Obstetrics and Gynaecology Canada","issn_l":"1701-2163","issn":["1701-2163","2665-9867"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Obstetrics and Gynaecology Canada","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064396212","display_name":"Amanda Black","orcid":"https://orcid.org/0000-0002-2245-3428","observed_orcids":["https://orcid.org/0000-0002-2245-3428"]},"institutions":[{"id":"https://openalex.org/I4388482656","display_name":"Ottawa Hospital Research Institute","ror":"https://ror.org/05jtef216","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I153718931","https://openalex.org/I2800722420","https://openalex.org/I4388482656"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Amanda Black","raw_affiliation_strings":["Ottawa Hospital Research Institute, 501 Smyth Box 511, Ottawa, ON K1H 8L6"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ottawa Hospital Research Institute, 501 Smyth Box 511, Ottawa, ON K1H 8L6","institution_ids":["https://openalex.org/I4388482656"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021933390","display_name":"Kristina Gemzell\u2010Danielsson","orcid":"https://orcid.org/0000-0001-6516-1444","observed_orcids":["https://orcid.org/0000-0001-6516-1444"]},"institutions":[{"id":"https://openalex.org/I4388482656","display_name":"Ottawa Hospital Research Institute","ror":"https://ror.org/05jtef216","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I153718931","https://openalex.org/I2800722420","https://openalex.org/I4388482656"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Kristina Gemzell-Danielsson","raw_affiliation_strings":["Ottawa Hospital Research Institute, 501 Smyth Box 511, Ottawa, ON K1H 8L6"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ottawa Hospital Research Institute, 501 Smyth Box 511, Ottawa, ON K1H 8L6","institution_ids":["https://openalex.org/I4388482656"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027747421","display_name":"Kai Haldre","orcid":"https://orcid.org/0000-0002-0260-986X","observed_orcids":["https://orcid.org/0000-0002-0260-986X"]},"institutions":[{"id":"https://openalex.org/I4388482656","display_name":"Ottawa Hospital Research Institute","ror":"https://ror.org/05jtef216","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I153718931","https://openalex.org/I2800722420","https://openalex.org/I4388482656"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Kai Haldre","raw_affiliation_strings":["Ottawa Hospital Research Institute, 501 Smyth Box 511, Ottawa, ON K1H 8L6"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ottawa Hospital Research Institute, 501 Smyth Box 511, Ottawa, ON K1H 8L6","institution_ids":["https://openalex.org/I4388482656"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018752041","display_name":"Guillaume Chatel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4388482656","display_name":"Ottawa Hospital Research Institute","ror":"https://ror.org/05jtef216","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I153718931","https://openalex.org/I2800722420","https://openalex.org/I4388482656"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Guillaume Chatel","raw_affiliation_strings":["Ottawa Hospital Research Institute, 501 Smyth Box 511, Ottawa, ON K1H 8L6"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ottawa Hospital Research Institute, 501 Smyth Box 511, Ottawa, ON K1H 8L6","institution_ids":["https://openalex.org/I4388482656"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003297593","display_name":"Dan L Apter","orcid":"https://orcid.org/0000-0002-5175-8845","observed_orcids":["https://orcid.org/0000-0002-5175-8845"]},"institutions":[{"id":"https://openalex.org/I4388482656","display_name":"Ottawa Hospital Research Institute","ror":"https://ror.org/05jtef216","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I153718931","https://openalex.org/I2800722420","https://openalex.org/I4388482656"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Dan Apter","raw_affiliation_strings":["Ottawa Hospital Research Institute, 501 Smyth Box 511, Ottawa, ON K1H 8L6"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ottawa Hospital Research Institute, 501 Smyth Box 511, Ottawa, ON K1H 8L6","institution_ids":["https://openalex.org/I4388482656"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4388482656"],"apc_list":{"value":3100,"currency":"USD","value_usd":3100},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"47","issue":"6","first_page":"102847","last_page":"102847"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10600","display_name":"Reproductive Health and Contraception","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10600","display_name":"Reproductive Health and Contraception","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12547","display_name":"Pharmaceutical studies and practices","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11943","display_name":"Pharmacovigilance and Adverse Drug Reactions","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/estetrol","display_name":"estetrol","score":0.8690000176429749},{"id":"https://openalex.org/keywords/drospirenone","display_name":"drospirenone","score":0.996999979019165},{"id":"https://openalex.org/keywords/combined-oral-contraceptives","display_name":"combined oral contraceptives","score":0.8679999709129333},{"id":"https://openalex.org/keywords/adolescent-girls","display_name":"adolescent girls","score":0.527999997138977},{"id":"https://openalex.org/keywords/drug-safety","display_name":"drug safety","score":0.9070000052452087},{"id":"https://openalex.org/keywords/tolerability","display_name":"tolerability","score":0.9409999847412109},{"id":"https://openalex.org/keywords/adverse-events","display_name":"adverse events","score":0.8679999709129333},{"id":"https://openalex.org/keywords/bleeding-patterns","display_name":"bleeding patterns","score":0.5419999957084656}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.968061625957489},{"id":"https://openalex.org/C2778375690","wikidata":"https://www.wikidata.org/wiki/Q7814214","display_name":"Tolerability","level":3,"score":0.857995867729187},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3337050676345825},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.2405579686164856},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1648380160331726}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jogc.2025.102847","doi":"https://doi.org/10.1016/j.jogc.2025.102847","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jogc.2025.102847","pdf_url":null,"source":{"id":"https://openalex.org/S2755151586","display_name":"Journal of Obstetrics and Gynaecology Canada","issn_l":"1701-2163","issn":["1701-2163","2665-9867"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Obstetrics and Gynaecology Canada","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7135076312","https://openalex.org/W4417359086","https://openalex.org/W4411376227","https://openalex.org/W4378190362","https://openalex.org/W4388532323","https://openalex.org/W3008002591","https://openalex.org/W4306697786","https://openalex.org/W4406867173","https://openalex.org/W7170523424","https://openalex.org/W4280629820"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-17T09:40:24.721904","created_date":"2025-10-10T00:00:00"}