{"id":"https://openalex.org/W4411149122","doi":"https://doi.org/10.1016/j.toxicon.2025.108455","title":"Pain drawings in evaluating treatment benefit of botulin toxin in masticatory muscle pain","display_name":"Pain drawings in evaluating treatment benefit of botulin toxin in masticatory muscle pain","publication_year":2025,"publication_date":"2025-06-09","ids":{"openalex":"https://openalex.org/W4411149122","doi":"https://doi.org/10.1016/j.toxicon.2025.108455","pmid":"https://pubmed.ncbi.nlm.nih.gov/40499791"},"language":"en","primary_location":{"id":"doi:10.1016/j.toxicon.2025.108455","doi":"https://doi.org/10.1016/j.toxicon.2025.108455","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.toxicon.2025.108455","pdf_url":null,"source":{"id":"https://openalex.org/S42803210","display_name":"Toxicon","issn_l":"0041-0101","issn":["0041-0101","1879-3150"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicon","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.toxicon.2025.108455","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Alina Valli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I133731052","display_name":"University of Helsinki","ror":"https://ror.org/040af2s02","country_code":"FI","type":"education","lineage":["https://openalex.org/I133731052"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Alina Valli","raw_affiliation_strings":["Department of Oral and Maxillofacial Diseases, Faculty of Medicine, University of Helsinki, Helsinki, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral and Maxillofacial Diseases, Faculty of Medicine, University of Helsinki, Helsinki, Finland","institution_ids":["https://openalex.org/I133731052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062733663","display_name":"Victoria Sitnikova","orcid":"https://orcid.org/0000-0002-8742-1128","observed_orcids":["https://orcid.org/0000-0002-8742-1128"]},"institutions":[{"id":"https://openalex.org/I133731052","display_name":"University of Helsinki","ror":"https://ror.org/040af2s02","country_code":"FI","type":"education","lineage":["https://openalex.org/I133731052"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Victoria Sitnikova","raw_affiliation_strings":["Department of Oral and Maxillofacial Diseases, Faculty of Medicine, University of Helsinki, Helsinki, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral and Maxillofacial Diseases, Faculty of Medicine, University of Helsinki, Helsinki, Finland","institution_ids":["https://openalex.org/I133731052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013107553","display_name":"Pentti Kemppainen","orcid":"https://orcid.org/0000-0003-0555-4523","observed_orcids":["https://orcid.org/0000-0003-0555-4523"]},"institutions":[{"id":"https://openalex.org/I133731052","display_name":"University of Helsinki","ror":"https://ror.org/040af2s02","country_code":"FI","type":"education","lineage":["https://openalex.org/I133731052"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Pentti Kemppainen","raw_affiliation_strings":["Department of Oral and Maxillofacial Diseases, Faculty of Medicine, University of Helsinki, Helsinki, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oral and Maxillofacial Diseases, Faculty of Medicine, University of Helsinki, Helsinki, Finland","institution_ids":["https://openalex.org/I133731052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008340151","display_name":"Leena K\u00e4mppi","orcid":"https://orcid.org/0000-0001-5084-2159","observed_orcids":["https://orcid.org/0000-0001-5084-2159"]},"institutions":[{"id":"https://openalex.org/I133731052","display_name":"University of Helsinki","ror":"https://ror.org/040af2s02","country_code":"FI","type":"education","lineage":["https://openalex.org/I133731052"]},{"id":"https://openalex.org/I2800394112","display_name":"Helsinki University Hospital","ror":"https://ror.org/02e8hzf44","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I2800394112","https://openalex.org/I4210166427"]},{"id":"https://openalex.org/I4210166427","display_name":"Hospital District of Helsinki and Uusimaa","ror":"https://ror.org/020cpqb94","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I4210166427"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Leena K\u00e4mppi","raw_affiliation_strings":["Epilepsia Helsinki (Member of ERN EpiCARE), HUS Neurocenter, Helsinki, Finland; Department of Neuroscience, Faculty of Medicine, University of Helsinki, Helsinki, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epilepsia Helsinki (Member of ERN EpiCARE), HUS Neurocenter, Helsinki, Finland; Department of Neuroscience, Faculty of Medicine, University of Helsinki, Helsinki, Finland","institution_ids":["https://openalex.org/I133731052","https://openalex.org/I2800394112","https://openalex.org/I4210166427"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044773601","display_name":"Antti K\u00e4mppi","orcid":"https://orcid.org/0000-0003-4921-4045","observed_orcids":["https://orcid.org/0000-0003-4921-4045"]},"institutions":[{"id":"https://openalex.org/I133731052","display_name":"University of Helsinki","ror":"https://ror.org/040af2s02","country_code":"FI","type":"education","lineage":["https://openalex.org/I133731052"]},{"id":"https://openalex.org/I2800394112","display_name":"Helsinki University Hospital","ror":"https://ror.org/02e8hzf44","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I2800394112","https://openalex.org/I4210166427"]},{"id":"https://openalex.org/I4210166427","display_name":"Hospital District of Helsinki and Uusimaa","ror":"https://ror.org/020cpqb94","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I4210166427"]}],"countries":["FI"],"is_corresponding":true,"raw_author_name":"Leena K\u00e4mppi","raw_affiliation_strings":["Epilepsia Helsinki (Member of ERN EpiCARE), HUS Neurocenter, Helsinki, Finland; Department of Neuroscience, Faculty of Medicine, University of Helsinki, Helsinki, Finland","Department of Oral and Maxillofacial Diseases, Faculty of Medicine, University of Helsinki, Helsinki, Finland. Electronic address: Antti.Kamppi@helsinki.fi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Epilepsia Helsinki (Member of ERN EpiCARE), HUS Neurocenter, Helsinki, Finland; Department of Neuroscience, Faculty of Medicine, University of Helsinki, Helsinki, Finland","institution_ids":["https://openalex.org/I133731052","https://openalex.org/I2800394112","https://openalex.org/I4210166427"]},{"raw_affiliation_string":"Department of Oral and Maxillofacial Diseases, Faculty of Medicine, University of Helsinki, Helsinki, Finland. Electronic address: Antti.Kamppi@helsinki.fi","institution_ids":["https://openalex.org/I133731052"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044773601","display_name":"Antti K\u00e4mppi","orcid":"https://orcid.org/0000-0003-4921-4045","observed_orcids":["https://orcid.org/0000-0003-4921-4045"]},"institutions":[{"id":"https://openalex.org/I133731052","display_name":"University of Helsinki","ror":"https://ror.org/040af2s02","country_code":"FI","type":"education","lineage":["https://openalex.org/I133731052"]}],"countries":["FI"],"is_corresponding":true,"raw_author_name":"Antti K\u00e4mppi","raw_affiliation_strings":["Department of Oral and Maxillofacial Diseases, Faculty of Medicine, University of Helsinki, Helsinki, Finland. Electronic address: Antti.Kamppi@helsinki.fi"],"raw_orcid":"https://orcid.org/0000-0003-4921-4045","affiliations":[{"raw_affiliation_string":"Department of Oral and Maxillofacial Diseases, Faculty of Medicine, University of Helsinki, Helsinki, Finland. Electronic address: Antti.Kamppi@helsinki.fi","institution_ids":["https://openalex.org/I133731052"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5044773601"],"corresponding_institution_ids":["https://openalex.org/I133731052","https://openalex.org/I2800394112","https://openalex.org/I4210166427"],"apc_list":{"value":3340,"currency":"USD","value_usd":3340},"apc_paid":{"value":3340,"currency":"USD","value_usd":3340},"fwci":1.9768,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.84805435,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":97},"biblio":{"volume":"264","issue":null,"first_page":"108455","last_page":"108455"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10852","display_name":"Temporomandibular Joint Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3603","display_name":"Complementary and Manual Therapy"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10852","display_name":"Temporomandibular Joint Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3603","display_name":"Complementary and Manual Therapy"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11274","display_name":"Botulinum Toxin and Related Neurological Disorders","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12145","display_name":"Dental Anxiety and Anesthesia Techniques","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/botulinum-toxin-type-a","display_name":"botulinum toxin type A","score":0.9860000014305115},{"id":"https://openalex.org/keywords/temporomandibular-disorders","display_name":"temporomandibular disorders","score":0.8899999856948853},{"id":"https://openalex.org/keywords/masticatory-muscle-pain","display_name":"masticatory muscle pain","score":0.9169999957084656},{"id":"https://openalex.org/keywords/pain-drawings","display_name":"pain drawings","score":0.8190000057220459},{"id":"https://openalex.org/keywords/treatment-response","display_name":"treatment response","score":0.5929999947547913},{"id":"https://openalex.org/keywords/widespread-pain","display_name":"widespread pain","score":0.8190000057220459},{"id":"https://openalex.org/keywords/localized-pain","display_name":"localized pain","score":0.8709999918937683},{"id":"https://openalex.org/keywords/regional-pain","display_name":"regional pain","score":0.9300000071525574},{"id":"https://openalex.org/keywords/pain-intensity","display_name":"pain intensity","score":0.5139999985694885},{"id":"https://openalex.org/keywords/pain-related-disability","display_name":"pain-related disability","score":0.9599999785423279},{"id":"https://openalex.org/keywords/treatment-planning","display_name":"treatment planning","score":0.640999972820282}],"concepts":[{"id":"https://openalex.org/C193206974","wikidata":"https://www.wikidata.org/wiki/Q6785539","display_name":"Masticatory force","level":2,"score":0.7901400327682495},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5546311140060425},{"id":"https://openalex.org/C2777478456","wikidata":"https://www.wikidata.org/wiki/Q208413","display_name":"Botulinum toxin","level":2,"score":0.4527018070220947},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.3539344072341919},{"id":"https://openalex.org/C29694066","wikidata":"https://www.wikidata.org/wiki/Q118301","display_name":"Orthodontics","level":1,"score":0.2898271083831787},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2061208188533783}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008410","descriptor_name":"Masticatory Muscles","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008410","descriptor_name":"Masticatory Muscles","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008410","descriptor_name":"Masticatory Muscles","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009465","descriptor_name":"Neuromuscular Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D009465","descriptor_name":"Neuromuscular Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D009465","descriptor_name":"Neuromuscular Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D010147","descriptor_name":"Pain Measurement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010147","descriptor_name":"Pain Measurement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010147","descriptor_name":"Pain Measurement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013705","descriptor_name":"Temporomandibular Joint Disorders","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D013705","descriptor_name":"Temporomandibular Joint Disorders","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D013705","descriptor_name":"Temporomandibular Joint Disorders","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D018592","descriptor_name":"Cross-Over Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018592","descriptor_name":"Cross-Over Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018592","descriptor_name":"Cross-Over Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019274","descriptor_name":"Botulinum Toxins, Type A","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D019274","descriptor_name":"Botulinum Toxins, Type A","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D019274","descriptor_name":"Botulinum Toxins, Type A","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D063806","descriptor_name":"Myalgia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D063806","descriptor_name":"Myalgia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D063806","descriptor_name":"Myalgia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.toxicon.2025.108455","doi":"https://doi.org/10.1016/j.toxicon.2025.108455","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.toxicon.2025.108455","pdf_url":null,"source":{"id":"https://openalex.org/S42803210","display_name":"Toxicon","issn_l":"0041-0101","issn":["0041-0101","1879-3150"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicon","raw_type":"journal-article"},{"id":"pmid:40499791","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40499791","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicon : official journal of the International Society on Toxinology","raw_type":"Journal Article"},{"id":"pmh:oai:helda.helsinki.fi:10138/599880","doi":null,"is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.toxicon.2025.108455","pdf_url":null,"source":{"id":"https://openalex.org/S4210213322","display_name":"Ty\u00f6v\u00e4entutkimus Vuosikirja","issn_l":"0784-1272","issn":["0784-1272","1459-7780"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["jufo-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1016/j.toxicon.2025.108455","doi":"https://doi.org/10.1016/j.toxicon.2025.108455","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.toxicon.2025.108455","pdf_url":null,"source":{"id":"https://openalex.org/S42803210","display_name":"Toxicon","issn_l":"0041-0101","issn":["0041-0101","1879-3150"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicon","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.6100000143051147,"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320310086","display_name":"Helsingin Yliopisto","ror":"https://ror.org/040af2s02"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W194975818","https://openalex.org/W382074634","https://openalex.org/W2040484651","https://openalex.org/W2092118491","https://openalex.org/W2111198528","https://openalex.org/W2118555930","https://openalex.org/W2132555288","https://openalex.org/W2132968602","https://openalex.org/W2136831026","https://openalex.org/W2154154208","https://openalex.org/W2154798479","https://openalex.org/W2306507320","https://openalex.org/W2406721297","https://openalex.org/W2540524624","https://openalex.org/W2565949583","https://openalex.org/W2590907870","https://openalex.org/W2944620429","https://openalex.org/W2971868680","https://openalex.org/W3036410631","https://openalex.org/W3116165005","https://openalex.org/W3144075976","https://openalex.org/W3197870402","https://openalex.org/W4220671494","https://openalex.org/W4283748306","https://openalex.org/W4283770707","https://openalex.org/W4292513173","https://openalex.org/W4318689315","https://openalex.org/W4382343834","https://openalex.org/W4387893325","https://openalex.org/W4400321700","https://openalex.org/W6676546944"],"related_works":["https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W3031052312","https://openalex.org/W4389568370","https://openalex.org/W3032375762","https://openalex.org/W1995515455","https://openalex.org/W2080531066","https://openalex.org/W3108674512","https://openalex.org/W1506200166","https://openalex.org/W1489783725"],"abstract_inverted_index":{"OBJECTIVES:":[0],"Studies":[1],"on":[2,117,125],"the":[3,19,42,58,105,118,121,153,167,179,185,190,199,209,229],"use":[4],"of":[5,23,73,95,120,219],"botulinum":[6],"toxin":[7],"A":[8,92],"(BoNT-A)":[9],"in":[10,51,62,77,104,161,166,178,192,198,208,228,240,254],"TMD-related":[11],"myalgia":[12],"suggest":[13],"that":[14],"some":[15],"patients":[16,48,61,76,97,241,255],"benefit":[17],"from":[18,41],"injections.":[20,43],"The":[21,86,217],"aim":[22],"this":[24],"study":[25],"was":[26,88,102,141,164,195,225],"to":[27],"assess":[28],"which":[29],"patient":[30],"group,":[31],"regarding":[32],"pain":[33,122,127,136,162,193,206,220],"sites":[34],"and":[35,75,111,171,211,222,244],"self-reported":[36],"comorbid":[37],"pains,":[38],"benefits":[39],"most":[40,196],"MATERIALS":[44],"AND":[45],"METHODS:":[46],"66":[47],"were":[49,68,109],"enrolled":[50],"a":[52,158,263],"randomized,":[53],"double-blind,":[54],"cross-over":[55,87],"study.":[56],"In":[57,152,184],"first":[59],"period,":[60],"group":[63,78,181,201],"1":[64],"(n":[65,80],"=":[66,81],"33)":[67,82],"injected":[69],"with":[70,83,98,204,242,256],"50":[71],"U":[72],"BoNT-A,":[74],"2":[79],"saline":[84],"solution.":[85],"at":[89],"16":[90],"weeks.":[91],"final":[93],"cohort":[94],"54":[96],"full":[99],"follow-up":[100],"data":[101],"included":[103],"statistical":[106],"analyses.":[107],"Patients":[108],"pooled":[110],"divided":[112],"into":[113],"three":[114],"groups":[115,173],"depending":[116],"extent":[119],"areas":[123,163,194,213],"based":[124],"their":[126],"drawings":[128],"(PD):":[129],"regional":[130,245],"(RP),":[131],"local":[132],"(LP)":[133],"widespread":[134,257],"(WP)":[135],"groups.":[137],"Treatment":[138],"response":[139],"assessment":[140],"performed":[142],"using":[143],"Diagnostic":[144],"Criteria":[145],"for":[146,238,267],"Temporomandibular":[147],"Disorders":[148],"(DC/TMD)":[149],"tools.":[150],"RESULTS:":[151],"short":[154],"term":[155,187],"(2":[156],"weeks),":[157,189],"clear":[159],"reduction":[160,191,207,218],"observed":[165],"LP":[168],"(84.2":[169],"%)":[170],"RP":[172,200],"(80.9":[174],"%),":[175,203],"but":[176],"not":[177],"WP":[180,230],"(64.3":[182],"%).":[183],"long":[186],"(16":[188],"evident":[197,227],"(71.4":[202],"significant":[205],"shoulder":[210],"back":[212],"(p":[214],"<":[215],"0.05).":[216],"intensity":[221],"pain-related":[223],"disability":[224],"least":[226],"group.":[231],"CONCLUSION:":[232],"BoNT-A":[233],"injections":[234],"might":[235],"be":[236,252,262],"considered":[237,253],"treatment":[239,249,268],"localized":[243],"pain,":[246],"however":[247],"other":[248],"modalities":[250],"should":[251],"pain.":[258],"Pain":[259],"drawing":[260],"could":[261],"useful":[264],"screening":[265],"tool":[266],"planning.":[269]},"counts_by_year":[{"year":2026,"cited_by_count":2}],"updated_date":"2026-10-17T09:40:24.721904","created_date":"2025-10-10T00:00:00"}