{"id":"https://openalex.org/W4411098633","doi":"https://doi.org/10.1007/s11682-025-01021-w","title":"Diffusion basis spectrum imaging of white matter in schizophrenia and bipolar disorder","display_name":"Diffusion basis spectrum imaging of white matter in schizophrenia and bipolar disorder","publication_year":2025,"publication_date":"2025-06-06","ids":{"openalex":"https://openalex.org/W4411098633","doi":"https://doi.org/10.1007/s11682-025-01021-w","pmid":"https://pubmed.ncbi.nlm.nih.gov/39005300","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11245098"},"language":"en","primary_location":{"id":"doi:10.1007/s11682-025-01021-w","doi":"https://doi.org/10.1007/s11682-025-01021-w","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11682-025-01021-w","pdf_url":null,"source":{"id":"https://openalex.org/S51590970","display_name":"Brain Imaging and Behavior","issn_l":"1931-7557","issn":["1931-7557","1931-7565"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Imaging and Behavior","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.biorxiv.org/content/biorxiv/early/2024/07/07/2024.07.07.602402.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Daniel Mamah","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Daniel Mamah","raw_affiliation_strings":["Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid, Campus Box 8134, St. Louis, MO, 63110, USA. mamahd@wustl.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid, Campus Box 8134, St. Louis, MO, 63110, USA. mamahd@wustl.edu","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055942438","display_name":"Aakash Patel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aakash Patel","raw_affiliation_strings":["Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid, Campus Box 8134, St. Louis, MO, 63110, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid, Campus Box 8134, St. Louis, MO, 63110, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104237855","display_name":"ShingShiun Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"ShingShiun Chen","raw_affiliation_strings":["Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid, Campus Box 8134, St. Louis, MO, 63110, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid, Campus Box 8134, St. Louis, MO, 63110, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100424532","display_name":"Yong Wang","orcid":"https://orcid.org/0000-0003-2507-8333","observed_orcids":["https://orcid.org/0000-0003-2507-8333"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yong Wang","raw_affiliation_strings":["Department of Biomedical Engineering, Washington University School of Medicine, St. Louis, MO, USA","Department of Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA","Department of Mechanical Engineering and Materials Science, Washington University School of Medicine, St. Louis, MO, USA","Department of Obstetrics and Gynecology, Washington University School of Medicine, 4525 Scott Ave, Campus Box 8225, St. Louis, MO, 63110, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Washington University School of Medicine, St. Louis, MO, USA","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Department of Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Department of Mechanical Engineering and Materials Science, Washington University School of Medicine, St. Louis, MO, USA","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Washington University School of Medicine, 4525 Scott Ave, Campus Box 8225, St. Louis, MO, 63110, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100434806","display_name":"Qing Wang","orcid":"https://orcid.org/0000-0002-1296-7097","observed_orcids":["https://orcid.org/0000-0002-1296-7097"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Qing Wang","raw_affiliation_strings":["Department of Biomedical Engineering, Washington University School of Medicine, St. Louis, MO, USA. wangqing@wustl.edu","Department of Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA. wangqing@wustl.edu","Department of Mechanical Engineering and Materials Science, Washington University School of Medicine, St. Louis, MO, USA. wangqing@wustl.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Washington University School of Medicine, St. Louis, MO, USA. wangqing@wustl.edu","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Department of Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO, USA. wangqing@wustl.edu","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Department of Mechanical Engineering and Materials Science, Washington University School of Medicine, St. Louis, MO, USA. wangqing@wustl.edu","institution_ids":["https://openalex.org/I204465549"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5100434806"],"corresponding_institution_ids":["https://openalex.org/I204465549"],"apc_list":{"value":3790,"currency":"USD","value_usd":3790},"apc_paid":null,"fwci":2.5916,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.89227442,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"19","issue":"5","first_page":"1002","last_page":"1017"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9711999893188477,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9711999893188477,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.023600000888109207,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diffusion-basis-spectrum-imaging","display_name":"diffusion basis spectrum imaging","score":0.9919999837875366},{"id":"https://openalex.org/keywords/white-matter","display_name":"white matter","score":0.7110000252723694},{"id":"https://openalex.org/keywords/schizophrenia","display_name":"schizophrenia","score":0.9120000004768372},{"id":"https://openalex.org/keywords/bipolar-disorder","display_name":"bipolar disorder","score":1.0},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":0.9980000257492065},{"id":"https://openalex.org/keywords/cellularity","display_name":"cellularity","score":0.8289999961853027},{"id":"https://openalex.org/keywords/vasogenic-edema","display_name":"vasogenic edema","score":0.9490000009536743},{"id":"https://openalex.org/keywords/demyelination","display_name":"demyelination","score":0.9330000281333923},{"id":"https://openalex.org/keywords/axonal-density","display_name":"axon density","score":0.7870000004768372},{"id":"https://openalex.org/keywords/corpus-callosum","display_name":"corpus callosum","score":0.9350000023841858},{"id":"https://openalex.org/keywords/psychotic-symptoms","display_name":"psychotic symptoms","score":0.5920000076293945},{"id":"https://openalex.org/keywords/mood-symptoms","display_name":"mood symptoms","score":0.8180000185966492},{"id":"https://openalex.org/keywords/tract-based-spatial-statistics","display_name":"tract-based spatial statistics","score":0.578000009059906}],"concepts":[{"id":"https://openalex.org/C3018432486","wikidata":"https://www.wikidata.org/wiki/Q7575316","display_name":"Schizophrenia spectrum","level":3,"score":0.7950904965400696},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.6623231172561646},{"id":"https://openalex.org/C2781192897","wikidata":"https://www.wikidata.org/wiki/Q822050","display_name":"White matter","level":3,"score":0.6547901630401611},{"id":"https://openalex.org/C149550507","wikidata":"https://www.wikidata.org/wiki/Q899360","display_name":"Diffusion MRI","level":3,"score":0.60561203956604},{"id":"https://openalex.org/C14216870","wikidata":"https://www.wikidata.org/wiki/Q3872","display_name":"Neuropsychology","level":3,"score":0.5876269936561584},{"id":"https://openalex.org/C2776174506","wikidata":"https://www.wikidata.org/wiki/Q131755","display_name":"Bipolar disorder","level":3,"score":0.5516598224639893},{"id":"https://openalex.org/C69357855","wikidata":"https://www.wikidata.org/wiki/Q163214","display_name":"Diffusion","level":2,"score":0.4525713622570038},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.43742990493774414},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.41031524538993835},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.363770067691803},{"id":"https://openalex.org/C46141821","wikidata":"https://www.wikidata.org/wiki/Q209402","display_name":"Nuclear magnetic resonance","level":1,"score":0.3581434488296509},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.2882841229438782},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.28141236305236816},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.22887155413627625},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.1794997751712799},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.16676810383796692},{"id":"https://openalex.org/C2779727114","wikidata":"https://www.wikidata.org/wiki/Q170082","display_name":"Psychosis","level":2,"score":0.1563102900981903},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.1007/s11682-025-01021-w","doi":"https://doi.org/10.1007/s11682-025-01021-w","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11682-025-01021-w","pdf_url":null,"source":{"id":"https://openalex.org/S51590970","display_name":"Brain Imaging and Behavior","issn_l":"1931-7557","issn":["1931-7557","1931-7565"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Imaging and Behavior","raw_type":"journal-article"},{"id":"doi:10.1101/2024.07.07.602402","doi":"https://doi.org/10.1101/2024.07.07.602402","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1101/2024.07.07.602402","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2024/07/07/2024.07.07.602402.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"doi:10.21203/rs.3.rs-4940831/v1","doi":"https://doi.org/10.21203/rs.3.rs-4940831/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-4940831/v1","pdf_url":null,"source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},{"id":"pmid:39005300","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39005300","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"bioRxiv : the preprint server for biology","raw_type":"Journal Article"},{"id":"pmid:40478407","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40478407","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain imaging and behavior","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11245098","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11245098","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11245098/pdf/nihpp-2024.07.07.602402v1.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1101/2024.07.07.602402","doi":"https://doi.org/10.1101/2024.07.07.602402","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1101/2024.07.07.602402","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2024/07/07/2024.07.07.602402.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G3355011348","display_name":"Validation of Diffusion Basis Spectrum Imaging of Neuroinflammation in Schizophrenia","funder_award_id":"R21MH131962","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G596930740","display_name":"CONNECTOMICS IN PSYCHIATRIC CLASSIFICATION","funder_award_id":"R01MH104414","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G9000870155","display_name":"Quantitative Endogenous MRI Imaging of Neuroinflammation in AD","funder_award_id":"R01AG074909","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"}],"funders":[{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4411098633.pdf","grobid_xml":"https://content.openalex.org/works/W4411098633.grobid-xml"},"referenced_works_count":74,"referenced_works":["https://openalex.org/W836811641","https://openalex.org/W1596347442","https://openalex.org/W1967424170","https://openalex.org/W1974665574","https://openalex.org/W1977576092","https://openalex.org/W1983208069","https://openalex.org/W1984453610","https://openalex.org/W2000574253","https://openalex.org/W2017689077","https://openalex.org/W2019730036","https://openalex.org/W2027270401","https://openalex.org/W2028994155","https://openalex.org/W2029713109","https://openalex.org/W2040789766","https://openalex.org/W2048922260","https://openalex.org/W2049221816","https://openalex.org/W2067214598","https://openalex.org/W2080013202","https://openalex.org/W2081664670","https://openalex.org/W2089941999","https://openalex.org/W2102582359","https://openalex.org/W2104291482","https://openalex.org/W2104561062","https://openalex.org/W2106922481","https://openalex.org/W2118879132","https://openalex.org/W2121398326","https://openalex.org/W2122102786","https://openalex.org/W2126693856","https://openalex.org/W2127309075","https://openalex.org/W2127946463","https://openalex.org/W2146264275","https://openalex.org/W2149253331","https://openalex.org/W2150667092","https://openalex.org/W2158329357","https://openalex.org/W2162640984","https://openalex.org/W2166037226","https://openalex.org/W2168661252","https://openalex.org/W2213127880","https://openalex.org/W2305713069","https://openalex.org/W2399060753","https://openalex.org/W2412496260","https://openalex.org/W2470259419","https://openalex.org/W2507387536","https://openalex.org/W2530293556","https://openalex.org/W2581687280","https://openalex.org/W2587178939","https://openalex.org/W2588031085","https://openalex.org/W2594272198","https://openalex.org/W2743833068","https://openalex.org/W2767050687","https://openalex.org/W2777526463","https://openalex.org/W2791758041","https://openalex.org/W2799733011","https://openalex.org/W2810839306","https://openalex.org/W2890155115","https://openalex.org/W2891409559","https://openalex.org/W2898554771","https://openalex.org/W2903139838","https://openalex.org/W2906988424","https://openalex.org/W2911701742","https://openalex.org/W2914151665","https://openalex.org/W2922178832","https://openalex.org/W2955471975","https://openalex.org/W2981547366","https://openalex.org/W3000703443","https://openalex.org/W3134867462","https://openalex.org/W3160983020","https://openalex.org/W3177601553","https://openalex.org/W4206525951","https://openalex.org/W4210858381","https://openalex.org/W4291899378","https://openalex.org/W4312067184","https://openalex.org/W4312088019","https://openalex.org/W4391445799"],"related_works":["https://openalex.org/W7141460878","https://openalex.org/W7211986395","https://openalex.org/W2728327150","https://openalex.org/W2888526713","https://openalex.org/W1941005804","https://openalex.org/W4405668766","https://openalex.org/W4384008603","https://openalex.org/W2842921401","https://openalex.org/W4402573039","https://openalex.org/W2979163295"],"abstract_inverted_index":{"Abstract":[0],"Background:":[1],"Multiple":[2],"studies":[3,224],"point":[4],"to":[5,40,46,89,227,241],"the":[6,11,178,243],"role":[7],"of":[8,13,106,134,145,158,177,245],"neuroinflammation":[9],"in":[10,21,128,138,152,172,175,182,220],"pathophysiology":[12],"schizophrenia":[14,70],"(SCZ),":[15],"however,":[16],"there":[17],"have":[18],"been":[19],"few":[20],"vivo":[22],"tools":[23],"for":[24],"imaging":[25,31],"brain":[26],"inflammation.":[27],"Diffusion":[28],"basis":[29],"spectrum":[30],"(DBSI)":[32],"is":[33,217],"an":[34,150],"advanced":[35],"diffusion-based":[36],"MRI":[37,62],"method":[38],"developed":[39],"quantitatively":[41],"assess":[42],"microstructural":[43],"alternations":[44],"relating":[45],"neuroinflammation,":[47,210],"axonal":[48,147],"fiber,":[49],"and":[50,74,94,98,116,149,185,196,214,247],"other":[51],"white":[52,208],"matter":[53,209],"(WM)":[54],"pathologies.":[55],"Methods:":[56],"We":[57,83],"acquired":[58],"one-hour-long":[59],"high-directional":[60],"diffusion":[61,100],"data":[63],"from":[64],"young":[65],"control":[66,117],"(CON,":[67],"n":[68,72,78],"=27),":[69],"(SCZ,":[71],"=21),":[73],"bipolar":[75,221],"disorder":[76],"(BPD,":[77],"=21)":[79],"participants":[80],"aged":[81],"18-30.":[82],"applied":[84],"Tract-based":[85],"Spatial":[86],"Statistics":[87],"(TBSS)":[88],"allow":[90],"whole-brain":[91],"WM":[92,163,169],"analyses":[93],"compare":[95],"DBSI-derived":[96,129],"isotropic":[97],"anisotropic":[99],"measures":[101],"between":[102],"groups.":[103,200],"Clinical":[104],"relationships":[105],"DBSI":[107,188,231],"metrics":[108,189,232],"with":[109,194],"clinical":[110],"symptoms":[111,198],"were":[112,166],"assessed":[113],"across":[114,161,199],"SCZ":[115,121,205],"participants.":[118],"Results:":[119],"In":[120],"participants,":[122],"we":[123],"found":[124],"a":[125,136],"generalized":[126,207],"increase":[127,151],"cellularity":[130],"(a":[131,142,155],"putative":[132,143,156],"marker":[133,144,157],"neuroinflammation),":[135],"decrease":[137],"restricted":[139],"fiber":[140,212],"fraction":[141],"apparent":[146],"density),":[148],"extra-axonal":[153,186],"water":[154],"vasogenic":[159],"edema)":[160],"several":[162],"tracts.":[164],"There":[165],"only":[167],"minimal":[168],"abnormalities":[170],"noted":[171],"BPD,":[173],"mainly":[174],"regions":[176],"corpus":[179],"callosum":[180],"(increase":[181],"DTI-derived":[183],"RD":[184],"water).":[187],"showed":[190],"significant":[191],"partial":[192],"correlations":[193],"psychosis":[195,246],"mood":[197],"Conclusion:":[201],"Ourfindings":[202],"suggest":[203],"that":[204],"involves":[206],"decreased":[211],"density,":[213],"demyelination,":[215],"which":[216],"not":[218],"seen":[219],"disorder.":[222],"Larger":[223],"are":[225],"needed":[226],"identify":[228,235],"medication-related":[229],"effects.":[230],"could":[233],"help":[234],"high-risk":[236],"groups":[237],"requiring":[238],"early":[239],"interventions":[240],"prevent":[242],"onset":[244],"improve":[248],"outcomes.":[249]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2025-10-10T00:00:00"}