{"id":"https://openalex.org/W4410855152","doi":"https://doi.org/10.1002/cncr.35922","title":"Randomized controlled trial reporting guidelines should be updated to include information on subsequent treatments","display_name":"Randomized controlled trial reporting guidelines should be updated to include information on subsequent treatments","publication_year":2025,"publication_date":"2025-05-29","ids":{"openalex":"https://openalex.org/W4410855152","doi":"https://doi.org/10.1002/cncr.35922","pmid":"https://pubmed.ncbi.nlm.nih.gov/40440214"},"language":"en","primary_location":{"id":"doi:10.1002/cncr.35922","doi":"https://doi.org/10.1002/cncr.35922","is_oa":true,"landing_page_url":"https://doi.org/10.1002/cncr.35922","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cncr.35922","source":{"id":"https://openalex.org/S126033908","display_name":"Cancer","issn_l":"0008-543X","issn":["0008-543X","1045-7410","1097-0142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cncr.35922","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100436339","display_name":"Dawn Lee","orcid":"https://orcid.org/0000-0003-4027-8456","observed_orcids":["https://orcid.org/0000-0003-4027-8456","https://orcid.org/0000-0002-6385-0278"]},"institutions":[{"id":"https://openalex.org/I23923803","display_name":"University of Exeter","ror":"https://ror.org/03yghzc09","country_code":"GB","type":"education","lineage":["https://openalex.org/I23923803"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Dawn Lee","raw_affiliation_strings":["PenTAG University of Exeter Medical School St Luke's Campus  Exeter UK","PenTAG, University of Exeter Medical School, St Luke's Campus, Exeter, UK"],"raw_orcid":"https://orcid.org/0000-0003-4027-8456","affiliations":[{"raw_affiliation_string":"PenTAG University of Exeter Medical School St Luke's Campus  Exeter UK","institution_ids":["https://openalex.org/I23923803"]},{"raw_affiliation_string":"PenTAG, University of Exeter Medical School, St Luke's Campus, Exeter, UK","institution_ids":["https://openalex.org/I23923803"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059338067","display_name":"G. J. Mel\u00e9ndez\u2010Torres","orcid":"https://orcid.org/0000-0002-9823-4790","observed_orcids":["https://orcid.org/0000-0002-9823-4790"]},"institutions":[{"id":"https://openalex.org/I23923803","display_name":"University of Exeter","ror":"https://ror.org/03yghzc09","country_code":"GB","type":"education","lineage":["https://openalex.org/I23923803"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"G. J. Melendez Torres","raw_affiliation_strings":["PenTAG University of Exeter Medical School St Luke's Campus  Exeter UK","PenTAG, University of Exeter Medical School, St Luke's Campus, Exeter, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"PenTAG University of Exeter Medical School St Luke's Campus  Exeter UK","institution_ids":["https://openalex.org/I23923803"]},{"raw_affiliation_string":"PenTAG, University of Exeter Medical School, St Luke's Campus, Exeter, UK","institution_ids":["https://openalex.org/I23923803"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5100436339"],"corresponding_institution_ids":["https://openalex.org/I23923803"],"apc_list":{"value":4790,"currency":"USD","value_usd":4790},"apc_paid":{"value":4790,"currency":"USD","value_usd":4790},"fwci":1.2328,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.82912173,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"131","issue":"11","first_page":"e35922","last_page":"e35922"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10206","display_name":"Meta-analysis and systematic reviews","score":0.9115999937057495,"subfield":{"id":"https://openalex.org/subfields/1804","display_name":"Statistics, Probability and Uncertainty"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10206","display_name":"Meta-analysis and systematic reviews","score":0.9115999937057495,"subfield":{"id":"https://openalex.org/subfields/1804","display_name":"Statistics, Probability and Uncertainty"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11235","display_name":"Statistical Methods in Clinical Trials","score":0.05460000038146973,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10449","display_name":"Renal cell carcinoma treatment","score":0.006000000052154064,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/reporting-guidelines","display_name":"reporting guidelines","score":0.8820000290870667},{"id":"https://openalex.org/keywords/subsequent-treatment","display_name":"subsequent treatment","score":0.6240000128746033},{"id":"https://openalex.org/keywords/randomized-controlled-trials","display_name":"randomized controlled trials","score":0.7450000047683716},{"id":"https://openalex.org/keywords/renal-cell-carcinoma","display_name":"renal cell carcinoma","score":0.8899999856948853},{"id":"https://openalex.org/keywords/health-technology-assessment","display_name":"health technology assessment","score":0.8209999799728394},{"id":"https://openalex.org/keywords/cost-effectiveness","display_name":"cost-effectiveness","score":0.8259999752044678},{"id":"https://openalex.org/keywords/cancer-clinical-trials","display_name":"cancer clinical trials","score":0.6079999804496765},{"id":"https://openalex.org/keywords/trial-reporting-quality","display_name":"trial reporting quality","score":0.34599998593330383}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8748657703399658},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.7328325510025024},{"id":"https://openalex.org/C2777352838","wikidata":"https://www.wikidata.org/wiki/Q5419420","display_name":"Excellence","level":2,"score":0.5569514632225037},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.49554359912872314},{"id":"https://openalex.org/C160735492","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Health care","level":2,"score":0.4663723111152649},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.4138551354408264},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.4128660261631012},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.40625062584877014},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.3953402638435364},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3276328146457672},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.17295292019844055},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.09732481837272644},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C50522688","wikidata":"https://www.wikidata.org/wiki/Q189833","display_name":"Economic growth","level":1,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1002/cncr.35922","doi":"https://doi.org/10.1002/cncr.35922","is_oa":true,"landing_page_url":"https://doi.org/10.1002/cncr.35922","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cncr.35922","source":{"id":"https://openalex.org/S126033908","display_name":"Cancer","issn_l":"0008-543X","issn":["0008-543X","1045-7410","1097-0142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer","raw_type":"journal-article"},{"id":"pmid:40440214","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40440214","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12121698","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12121698","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cancer","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1002/cncr.35922","doi":"https://doi.org/10.1002/cncr.35922","is_oa":true,"landing_page_url":"https://doi.org/10.1002/cncr.35922","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cncr.35922","source":{"id":"https://openalex.org/S126033908","display_name":"Cancer","issn_l":"0008-543X","issn":["0008-543X","1045-7410","1097-0142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/16","display_name":"Peace, justice, and strong institutions","score":0.4699999988079071}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4410855152.pdf","grobid_xml":"https://content.openalex.org/works/W4410855152.grobid-xml"},"referenced_works_count":5,"referenced_works":["https://openalex.org/W2902350957","https://openalex.org/W3129780093","https://openalex.org/W3216105992","https://openalex.org/W4241454646","https://openalex.org/W4376875607"],"related_works":["https://openalex.org/W2154960005","https://openalex.org/W3012393071","https://openalex.org/W3125583970","https://openalex.org/W1508013896","https://openalex.org/W2080254889","https://openalex.org/W2028833986","https://openalex.org/W1996615648","https://openalex.org/W1970501475","https://openalex.org/W2038448004","https://openalex.org/W4285677568"],"abstract_inverted_index":{"This":[0],"paper":[1],"highlights":[2],"the":[3,80],"urgent":[4],"need":[5],"to":[6,13,78],"update":[7],"randomized":[8],"controlled":[9],"trial":[10],"reporting":[11,70],"guidelines":[12],"include":[14],"consistent":[15],"and":[16,32,44,49,62,76,86],"detailed":[17],"data":[18],"on":[19,36],"subsequent":[20,72],"treatments,":[21],"particularly":[22],"in":[23],"oncology,":[24],"where":[25],"postprogression":[26],"therapies":[27],"significantly":[28],"influence":[29],"overall":[30],"survival":[31],"cost\u2010effectiveness":[33],"assessments.":[34],"Drawing":[35],"our":[37],"experience":[38],"as":[39],"an":[40],"External":[41],"Assessment":[42],"Group":[43],"National":[45],"Institute":[46],"for":[47,68],"Health":[48],"Care":[50],"Excellence":[51],"Committee":[52],"members,":[53],"a":[54],"systematic":[55],"review":[56],"of":[57,71,82],"renal":[58],"cell":[59],"carcinoma":[60],"trials":[61],"broader":[63],"regulatory":[64],"guidance,":[65],"we":[66],"advocate":[67],"standardized":[69],"treatment":[73],"types,":[74],"timing,":[75],"durations":[77],"enhance":[79],"reliability":[81],"health":[83],"technology":[84],"assessments":[85],"support":[87],"more":[88],"informed":[89],"decision\u2010making.":[90]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2025-10-10T00:00:00"}