{"id":"https://openalex.org/W4410831782","doi":"https://doi.org/10.3390/jcm14113763","title":"Teratozoospermia and Embryo Development: The Significance of Sperm Selection in In Vitro Fertilization Success","display_name":"Teratozoospermia and Embryo Development: The Significance of Sperm Selection in In Vitro Fertilization Success","publication_year":2025,"publication_date":"2025-05-27","ids":{"openalex":"https://openalex.org/W4410831782","doi":"https://doi.org/10.3390/jcm14113763","pmid":"https://pubmed.ncbi.nlm.nih.gov/40507525","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12156187"},"language":"en","primary_location":{"id":"doi:10.3390/jcm14113763","doi":"https://doi.org/10.3390/jcm14113763","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm14113763","pdf_url":"https://www.mdpi.com/2077-0383/14/11/3763/pdf?version=1748358977","source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2077-0383/14/11/3763/pdf?version=1748358977","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039270071","display_name":"Petronela Naghi","orcid":"https://orcid.org/0000-0002-1440-3965","observed_orcids":["https://orcid.org/0000-0002-1440-3965"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Petronela Naghi","raw_affiliation_strings":["Calla\u2014Infertility Diagnostic and Treatment Center, Constantin A. Rosetti Street, 410103 Oradea, Romania"],"raw_orcid":"https://orcid.org/0000-0002-1440-3965","affiliations":[{"raw_affiliation_string":"Calla\u2014Infertility Diagnostic and Treatment Center, Constantin A. Rosetti Street, 410103 Oradea, Romania","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037887104","display_name":"Ioana Alexandra Zaha","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I162871001","display_name":"University of Oradea","ror":"https://ror.org/00wzhv093","country_code":"RO","type":"education","lineage":["https://openalex.org/I162871001"]}],"countries":["RO"],"is_corresponding":false,"raw_author_name":"Ioana Alexandra Zaha","raw_affiliation_strings":["Calla\u2014Infertility Diagnostic and Treatment Center, Constantin A. Rosetti Street, 410103 Oradea, Romania","Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania","Pelican Clinical Hospital, Corneliu Coposu Street 2, 410450 Oradea, Romania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Calla\u2014Infertility Diagnostic and Treatment Center, Constantin A. Rosetti Street, 410103 Oradea, Romania","institution_ids":[]},{"raw_affiliation_string":"Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania","institution_ids":["https://openalex.org/I162871001"]},{"raw_affiliation_string":"Pelican Clinical Hospital, Corneliu Coposu Street 2, 410450 Oradea, Romania","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088795690","display_name":"Liana \u0218tefan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I162871001","display_name":"University of Oradea","ror":"https://ror.org/00wzhv093","country_code":"RO","type":"education","lineage":["https://openalex.org/I162871001"]}],"countries":["RO"],"is_corresponding":true,"raw_author_name":"Liana Stefan","raw_affiliation_strings":["Calla\u2014Infertility Diagnostic and Treatment Center, Constantin A. Rosetti Street, 410103 Oradea, Romania","Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania","Oradea County Hospital, Gheorghe Doja Street 65\u201367, 410169 Oradea, Romania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Calla\u2014Infertility Diagnostic and Treatment Center, Constantin A. Rosetti Street, 410103 Oradea, Romania","institution_ids":[]},{"raw_affiliation_string":"Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania","institution_ids":["https://openalex.org/I162871001"]},{"raw_affiliation_string":"Oradea County Hospital, Gheorghe Doja Street 65\u201367, 410169 Oradea, Romania","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006085640","display_name":"Andrea Sorian","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrea Sorian","raw_affiliation_strings":["Calla\u2014Infertility Diagnostic and Treatment Center, Constantin A. Rosetti Street, 410103 Oradea, Romania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Calla\u2014Infertility Diagnostic and Treatment Center, Constantin A. Rosetti Street, 410103 Oradea, Romania","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Adelin Marcu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Adelin Marcu","raw_affiliation_strings":["Calla\u2014Infertility Diagnostic and Treatment Center, Constantin A. Rosetti Street, 410103 Oradea, Romania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Calla\u2014Infertility Diagnostic and Treatment Center, Constantin A. Rosetti Street, 410103 Oradea, Romania","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059754867","display_name":"Liliana Sachelarie","orcid":"https://orcid.org/0000-0001-7701-2307","observed_orcids":["https://orcid.org/0000-0001-7701-2307"]},"institutions":[{"id":"https://openalex.org/I3129623846","display_name":"Apollonia University","ror":"https://ror.org/026mhap18","country_code":"RO","type":"education","lineage":["https://openalex.org/I3129623846"]}],"countries":["RO"],"is_corresponding":true,"raw_author_name":"Liliana Sachelarie","raw_affiliation_strings":["Department of Clinical Discipline, Apollonia University, 700511 Iasi, Romania"],"raw_orcid":"https://orcid.org/0000-0001-7701-2307","affiliations":[{"raw_affiliation_string":"Department of Clinical Discipline, Apollonia University, 700511 Iasi, Romania","institution_ids":["https://openalex.org/I3129623846"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076005023","display_name":"Anca Carmen Huniadi","orcid":"https://orcid.org/0000-0002-5998-9488","observed_orcids":["https://orcid.org/0000-0002-5998-9488"]},"institutions":[{"id":"https://openalex.org/I162871001","display_name":"University of Oradea","ror":"https://ror.org/00wzhv093","country_code":"RO","type":"education","lineage":["https://openalex.org/I162871001"]}],"countries":["RO"],"is_corresponding":false,"raw_author_name":"Anca Huniadi","raw_affiliation_strings":["Calla\u2014Infertility Diagnostic and Treatment Center, Constantin A. Rosetti Street, 410103 Oradea, Romania","Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania","Oradea County Hospital, Gheorghe Doja Street 65\u201367, 410169 Oradea, Romania","Pelican Clinical Hospital, Corneliu Coposu Street 2, 410450 Oradea, Romania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Calla\u2014Infertility Diagnostic and Treatment Center, Constantin A. Rosetti Street, 410103 Oradea, Romania","institution_ids":[]},{"raw_affiliation_string":"Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania","institution_ids":["https://openalex.org/I162871001"]},{"raw_affiliation_string":"Oradea County Hospital, Gheorghe Doja Street 65\u201367, 410169 Oradea, Romania","institution_ids":[]},{"raw_affiliation_string":"Pelican Clinical Hospital, Corneliu Coposu Street 2, 410450 Oradea, Romania","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5059754867","https://openalex.org/A5088795690"],"corresponding_institution_ids":["https://openalex.org/I162871001","https://openalex.org/I3129623846"],"apc_list":{"value":2600,"currency":"CHF","value_usd":3137},"apc_paid":{"value":2600,"currency":"CHF","value_usd":3137},"fwci":4.5213,"has_fulltext":true,"cited_by_count":8,"citation_normalized_percentile":{"value":0.95004555,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"14","issue":"11","first_page":"3763","last_page":"3763"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11156","display_name":"Reproductive Health and Technologies","score":0.0035000001080334187,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/teratozoospermia","display_name":"teratozoospermia","score":1.0},{"id":"https://openalex.org/keywords/sperm-selection","display_name":"sperm selection","score":0.8859999775886536},{"id":"https://openalex.org/keywords/microfluidic-sperm-sorting","display_name":"microfluidic sperm sorting","score":0.9229999780654907},{"id":"https://openalex.org/keywords/density-gradient-centrifugation","display_name":"density gradient centrifugation","score":0.9869999885559082},{"id":"https://openalex.org/keywords/fertilization-rate","display_name":"fertilization rate","score":0.9269999861717224},{"id":"https://openalex.org/keywords/blastocyst-development","display_name":"blastocyst development","score":0.9660000205039978},{"id":"https://openalex.org/keywords/embryo-quality","display_name":"embryo quality","score":0.9860000014305115},{"id":"https://openalex.org/keywords/in-vitro-fertilization","display_name":"in vitro fertilization","score":0.777999997138977},{"id":"https://openalex.org/keywords/embryo-viability-prediction","display_name":"embryo viability prediction","score":0.5519999861717224}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8649054765701294},{"id":"https://openalex.org/C512716672","wikidata":"https://www.wikidata.org/wiki/Q200117","display_name":"In vitro fertilisation","level":3,"score":0.7212418913841248},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.7153948545455933},{"id":"https://openalex.org/C88972607","wikidata":"https://www.wikidata.org/wiki/Q2666904","display_name":"Human fertilization","level":2,"score":0.6569615602493286},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.5953147411346436},{"id":"https://openalex.org/C2781087480","wikidata":"https://www.wikidata.org/wiki/Q17145","display_name":"Sperm","level":2,"score":0.5678055286407471},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.5566622614860535},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.15684381127357483},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.0899079442024231},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.06941905617713928},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.05065348744392395},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.3390/jcm14113763","doi":"https://doi.org/10.3390/jcm14113763","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm14113763","pdf_url":"https://www.mdpi.com/2077-0383/14/11/3763/pdf?version=1748358977","source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12156187","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12156187","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Clin Med","raw_type":"Text"},{"id":"pmid:40507525","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40507525","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical medicine","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.3390/jcm14113763","doi":"https://doi.org/10.3390/jcm14113763","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm14113763","pdf_url":"https://www.mdpi.com/2077-0383/14/11/3763/pdf?version=1748358977","source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4410831782.pdf","grobid_xml":"https://content.openalex.org/works/W4410831782.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W1520265251","https://openalex.org/W1714560337","https://openalex.org/W1989070741","https://openalex.org/W1997381325","https://openalex.org/W2006693497","https://openalex.org/W2041482906","https://openalex.org/W2057733697","https://openalex.org/W2082995757","https://openalex.org/W2083055659","https://openalex.org/W2117637119","https://openalex.org/W2136339263","https://openalex.org/W2159005332","https://openalex.org/W2171354278","https://openalex.org/W2792883455","https://openalex.org/W2801707844","https://openalex.org/W2803274958","https://openalex.org/W2998014993","https://openalex.org/W2999139181","https://openalex.org/W3107120073","https://openalex.org/W3119074607","https://openalex.org/W3197184091","https://openalex.org/W3208498782","https://openalex.org/W4206643024","https://openalex.org/W4211005481","https://openalex.org/W4229876987","https://openalex.org/W4310951130","https://openalex.org/W4316038977","https://openalex.org/W4323349804","https://openalex.org/W4385381372","https://openalex.org/W4387457973","https://openalex.org/W4388822328","https://openalex.org/W4389407327","https://openalex.org/W4392194026","https://openalex.org/W4405330680","https://openalex.org/W6750897533"],"related_works":["https://openalex.org/W3129038534","https://openalex.org/W1992944887","https://openalex.org/W2101718668","https://openalex.org/W2117637119","https://openalex.org/W2394507495","https://openalex.org/W4400296439","https://openalex.org/W2058090314","https://openalex.org/W2138132783","https://openalex.org/W7096320227","https://openalex.org/W4402956875"],"abstract_inverted_index":{"Background:":[0],"Sperm":[1,64,82],"morphology":[2],"is":[3],"a":[4],"key":[5],"factor":[6],"influencing":[7],"fertilization":[8,95,125,146,209,231],"and":[9,25,41,46,90,99,114,130,139,150,155,161,176,187,198,214,232,238],"embryo":[10,42,100,193,245,255],"development":[11,157],"in":[12,261],"assisted":[13],"reproductive":[14],"technology":[15],"(ART).":[16],"However,":[17],"the":[18,33,81,167,185,236],"predictive":[19,242],"value":[20,243],"of":[21,35,192,249],"sperm":[22,48,75,205,251],"deformity":[23],"indices":[24],"selection":[26,49,65,206,252],"techniques":[27],"remains":[28],"debated.":[29],"This":[30],"study":[31],"evaluated":[32],"impact":[34],"teratozoospermia":[36,122,228],"on":[37,57],"fertilization,":[38],"blastocyst":[39,97,132,156,216,233],"formation,":[40,98,234],"quality,":[43,256],"comparing":[44],"conventional":[45],"microfluidic":[47,74,204,250],"methods.":[50],"Methods:":[51],"A":[52],"retrospective":[53],"analysis":[54,105,182],"was":[55,66],"conducted":[56],"ART":[58],"cycles":[59],"involving":[60],"patients":[61],"with":[62,94,120,145,224,235],"teratozoospermia.":[63],"performed":[67],"using":[68],"density":[69],"gradient":[70],"centrifugation":[71],"(DGC)":[72],"or":[73],"sorting":[76],"(MFSS).":[77],"The":[78,137,247],"correlations":[79,144],"between":[80],"Deformity":[83],"Index":[84,88,92],"(SDI),":[85],"Multiple":[86],"Anomalies":[87],"(MAI),":[89],"Teratozoopermia":[91],"(TZI)":[93],"rates,":[96],"quality":[101,217],"were":[102,189],"assessed.":[103],"Statistical":[104],"included":[106],"correlation":[107],"tests,":[108],"receiver":[109],"operating":[110],"characteristic":[111],"(ROC)":[112],"curves,":[113],"independent":[115],"samples":[116],"t-tests.":[117],"Results:":[118],"Patients":[119,201],"severe":[121],"exhibited":[123],"lower":[124],"rates":[126,210],"(p":[127,134,211,218],"<":[128],"0.01)":[129],"reduced":[131],"formation":[133],"=":[135,148,152,159,163,174,178,196,212,219],"0.02).":[136],"SDI":[138,186,237],"MAI":[140,188,239],"showed":[141],"moderate":[142,190,241],"negative":[143],"(r":[147,158,173],"\u22120.15":[149],"r":[151,162,177],"\u22120.25,":[153],"respectively)":[154],"\u22120.20":[160],"\u22120.30,":[164],"respectively),":[165],"while":[166],"TZI":[168],"had":[169,207],"only":[170],"weak":[171],"associations":[172],"\u22120.10":[175],"\u22120.15,":[179],"respectively).":[180,200],"ROC":[181],"demonstrated":[183],"that":[184],"predictors":[191],"viability":[194],"(AUC":[195],"0.70":[197],"0.75,":[199],"who":[202],"underwent":[203],"higher":[208],"0.03)":[213],"improved":[215,254],"0.04)":[220],"than":[221],"those":[222],"processed":[223],"DGC.":[225],"Conclusions:":[226],"Severe":[227],"negatively":[229],"affects":[230],"showing":[240],"for":[244],"development.":[246],"use":[248],"significantly":[253],"supporting":[257],"its":[258],"clinical":[259],"relevance":[260],"ART.":[262]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2025-10-10T00:00:00"}